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The map label for this gene is ahpC [C]

Identifier: 194334393

GI number: 194334393

Start: 1730166

End: 1730756

Strand: Reverse

Name: ahpC [C]

Synonym: Paes_1588

Alternate gene names: 194334393

Gene position: 1730756-1730166 (Counterclockwise)

Preceding gene: 194334396

Following gene: 194334390

Centisome position: 68.87

GC content: 48.9

Gene sequence:

>591_bases
ATGGGCGTTCTGGTTGGTCGCGAAGCACCTGATTTTAGTCTCGATGCCGTCGTGGATGGCGGAAAAATGGTCGATTCGTG
CAAGTTGTCGGATTACAGGGGCAAATATGTTGTTCTGTTTTTCTATCCTCTTGATTTTACTTTTGTCTGTCCAACGGAGC
TTCACGCCTTTCAGGACAGGATTGATGAGTTTCGGCATAAAAATGTTGAGGTGATGGCCTGTTCGGTGGACTCGAAGTTT
TCTCACCACGCCTGGTTGAATACTCCGCGCAGTCAGGGGGGAATTCAGGGTGTGACCTATACGCTGCTCTCCGATATCAA
CAAGGAAGCTGCGAAGGCTTATGATGTTCTTGCTGAAGCAGAGGGGGTTTCATATAGAGGACTTTTCCTGATCGATCGTG
AAGGTATTGTTCGTTACCAGGTTGTCAACGATCTCGGTCTTGGTCGAAATGTCGATGAGGTGCTCCGGATGGTCGAAGCG
CTGCAGTTTACAGAAGAGTTCGGTGAGGTATGCCCGGCTAACTGGCATAAAGGCGCCAGGACCATGAAGCCGACAGATGA
AGGACTCAAAGAGTATTTCAAGTCAGAATAG

Upstream 100 bases:

>100_bases
TTGTGTGTTTTGTATATTGGATACAAATAGTCCTATTTATAAGGGGCGTATTGAGAATTCTTGAATTTTATCAAATTTCA
TTCAATAGAAGGAGATCGTT

Downstream 100 bases:

>100_bases
GTCTGCCGTGTCTGTTTGATGCACATGGTGCGTGCAAAAACGCTAAAGCCTGTTTCCCTCTGAAGGAAACGGGCTTTAGC
GTTTTGAGCGGTCAGTAGGC

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MGVLVGREAPDFSLDAVVDGGKMVDSCKLSDYRGKYVVLFFYPLDFTFVCPTELHAFQDRIDEFRHKNVEVMACSVDSKF
SHHAWLNTPRSQGGIQGVTYTLLSDINKEAAKAYDVLAEAEGVSYRGLFLIDREGIVRYQVVNDLGLGRNVDEVLRMVEA
LQFTEEFGEVCPANWHKGARTMKPTDEGLKEYFKSE

Sequences:

>Translated_196_residues
MGVLVGREAPDFSLDAVVDGGKMVDSCKLSDYRGKYVVLFFYPLDFTFVCPTELHAFQDRIDEFRHKNVEVMACSVDSKF
SHHAWLNTPRSQGGIQGVTYTLLSDINKEAAKAYDVLAEAEGVSYRGLFLIDREGIVRYQVVNDLGLGRNVDEVLRMVEA
LQFTEEFGEVCPANWHKGARTMKPTDEGLKEYFKSE
>Mature_195_residues
GVLVGREAPDFSLDAVVDGGKMVDSCKLSDYRGKYVVLFFYPLDFTFVCPTELHAFQDRIDEFRHKNVEVMACSVDSKFS
HHAWLNTPRSQGGIQGVTYTLLSDINKEAAKAYDVLAEAEGVSYRGLFLIDREGIVRYQVVNDLGLGRNVDEVLRMVEAL
QFTEEFGEVCPANWHKGARTMKPTDEGLKEYFKSE

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=189, Percent_Identity=55.026455026455, Blast_Score=224, Evalue=4e-59,
Organism=Homo sapiens, GI4505591, Length=192, Percent_Identity=53.6458333333333, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI32455266, Length=192, Percent_Identity=53.6458333333333, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI32455264, Length=192, Percent_Identity=53.6458333333333, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI5453549, Length=189, Percent_Identity=53.4391534391534, Blast_Score=213, Evalue=8e-56,
Organism=Homo sapiens, GI5802974, Length=190, Percent_Identity=52.1052631578947, Blast_Score=210, Evalue=5e-55,
Organism=Homo sapiens, GI32483377, Length=187, Percent_Identity=52.4064171122995, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=61.7283950617284, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI4758638, Length=191, Percent_Identity=30.8900523560209, Blast_Score=87, Evalue=7e-18,
Organism=Escherichia coli, GI1786822, Length=156, Percent_Identity=37.1794871794872, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32565831, Length=191, Percent_Identity=53.9267015706806, Blast_Score=214, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI193204376, Length=191, Percent_Identity=53.9267015706806, Blast_Score=214, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17554494, Length=184, Percent_Identity=54.8913043478261, Blast_Score=208, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI25153706, Length=185, Percent_Identity=25.9459459459459, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=195, Percent_Identity=49.2307692307692, Blast_Score=197, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6320661, Length=191, Percent_Identity=48.1675392670157, Blast_Score=189, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6319407, Length=190, Percent_Identity=32.6315789473684, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357347, Length=190, Percent_Identity=54.2105263157895, Blast_Score=218, Evalue=2e-57,
Organism=Drosophila melanogaster, GI17738015, Length=194, Percent_Identity=54.639175257732, Blast_Score=213, Evalue=8e-56,
Organism=Drosophila melanogaster, GI17157991, Length=189, Percent_Identity=52.3809523809524, Blast_Score=210, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24641739, Length=189, Percent_Identity=52.3809523809524, Blast_Score=210, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24656348, Length=190, Percent_Identity=51.0526315789474, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17864676, Length=190, Percent_Identity=51.0526315789474, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24581278, Length=153, Percent_Identity=32.6797385620915, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17975518, Length=188, Percent_Identity=34.0425531914894, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24652436, Length=188, Percent_Identity=34.0425531914894, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24652434, Length=188, Percent_Identity=34.0425531914894, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22132; Mature: 22001

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVLVGREAPDFSLDAVVDGGKMVDSCKLSDYRGKYVVLFFYPLDFTFVCPTELHAFQDR
CCEECCCCCCCCCEEEEECCCCCHHHCCCCCCCCCEEEEEEECCCEEEECCHHHHHHHHH
IDEFRHKNVEVMACSVDSKFSHHAWLNTPRSQGGIQGVTYTLLSDINKEAAKAYDVLAEA
HHHHHCCCEEEEEEECCCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHC
EGVSYRGLFLIDREGIVRYQVVNDLGLGRNVDEVLRMVEALQFTEEFGEVCPANWHKGAR
CCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TMKPTDEGLKEYFKSE
CCCCCHHHHHHHHCCC
>Mature Secondary Structure 
GVLVGREAPDFSLDAVVDGGKMVDSCKLSDYRGKYVVLFFYPLDFTFVCPTELHAFQDR
CEECCCCCCCCCEEEEECCCCCHHHCCCCCCCCCEEEEEEECCCEEEECCHHHHHHHHH
IDEFRHKNVEVMACSVDSKFSHHAWLNTPRSQGGIQGVTYTLLSDINKEAAKAYDVLAEA
HHHHHCCCEEEEEEECCCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHC
EGVSYRGLFLIDREGIVRYQVVNDLGLGRNVDEVLRMVEALQFTEEFGEVCPANWHKGAR
CCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TMKPTDEGLKEYFKSE
CCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]