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The map label for this gene is coaX [H]

Identifier: 193214349

GI number: 193214349

Start: 739648

End: 740469

Strand: Direct

Name: coaX [H]

Synonym: Ctha_0631

Alternate gene names: 193214349

Gene position: 739648-740469 (Clockwise)

Preceding gene: 193214348

Following gene: 193214358

Centisome position: 22.46

GC content: 45.01

Gene sequence:

>822_bases
ATGACGCCACGCAACCATTTAGTCAAACAACCCAATTTATCTTCGATCGCAACAGTTGATATTGGAAATACCCAAACATC
GATTGCCATTTTCGAAGGCGATGAATTAAAAGAATTTGAGCGATTTTCCTCCAAAAATTTAGAGAGTAAAAGTGCGCTGC
CAGATTTTTGTCAAAAATGCCAGTCGCTTGTGGGATCTGCGCCGCTGATTGCCATGTCGAGCGTTGTTCCCAATGTGGCC
TCTGCGCTGAAAACCATGTTTCATCAGCAATTTAGCGAAAAGCCAATTTTTGAAATCACTTATCAAACAAAACTGCCGTT
CCATATTCGCTATCAAACACCCGAAACGCTCGGCAACGATCGGCTGGCGCTTTGCGCAGCTGCTTGCGAGCGATTTCCAA
ACCAAGCTGTGATGATCATTGATTTTGGAACAGCCATCACTTACGACGTTTTAAATTCAAAGCATGAATATTTAGGCGGG
CTCATTTTAGCCGGAACGTCTCTTTCAGCGCGGGCGCTCAACGAGCATACAGCGCAGCTTCCTGCAATTGGGCTGCAAAA
AGAATCCGGCATTATTGGCAGAAATACTCGTGATTGCCTTTCAAAAGGACTTTTTTGGGGCACAGTCGCCCAAACTGAAG
GCTTGATTTTAAAACTGAAAAGCGAGTTAGCAGAAGAACATGGAGAACCAGAAGTAAAAGTGCTGATAACAGGTGGAAAT
AGCGTCACGCTGGCCGGCGCGATGCCGCACATTGACATTCGGGATGAATTTGCCATTCATAAAGGCATTCGGTTCATTGC
GGCACTAAACACAAATAGATGA

Upstream 100 bases:

>100_bases
CGCCATCGATATTGATGATTATGGCTATTTGAGGGTGAGAGTTGGCGCAACGGCTCTCATGCTCTCTCATGCGGAGATTT
CTAACGTTAGATTTTAAGCA

Downstream 100 bases:

>100_bases
AAATCTACACTTACTAACTTCGTAAAATATGCGCCGGGGAAACGTAAAGAGGCCACTTGAAAAAGTGGCCTCTTTCATTT
TATCAACATGATCCGTTTGC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MTPRNHLVKQPNLSSIATVDIGNTQTSIAIFEGDELKEFERFSSKNLESKSALPDFCQKCQSLVGSAPLIAMSSVVPNVA
SALKTMFHQQFSEKPIFEITYQTKLPFHIRYQTPETLGNDRLALCAAACERFPNQAVMIIDFGTAITYDVLNSKHEYLGG
LILAGTSLSARALNEHTAQLPAIGLQKESGIIGRNTRDCLSKGLFWGTVAQTEGLILKLKSELAEEHGEPEVKVLITGGN
SVTLAGAMPHIDIRDEFAIHKGIRFIAALNTNR

Sequences:

>Translated_273_residues
MTPRNHLVKQPNLSSIATVDIGNTQTSIAIFEGDELKEFERFSSKNLESKSALPDFCQKCQSLVGSAPLIAMSSVVPNVA
SALKTMFHQQFSEKPIFEITYQTKLPFHIRYQTPETLGNDRLALCAAACERFPNQAVMIIDFGTAITYDVLNSKHEYLGG
LILAGTSLSARALNEHTAQLPAIGLQKESGIIGRNTRDCLSKGLFWGTVAQTEGLILKLKSELAEEHGEPEVKVLITGGN
SVTLAGAMPHIDIRDEFAIHKGIRFIAALNTNR
>Mature_272_residues
TPRNHLVKQPNLSSIATVDIGNTQTSIAIFEGDELKEFERFSSKNLESKSALPDFCQKCQSLVGSAPLIAMSSVVPNVAS
ALKTMFHQQFSEKPIFEITYQTKLPFHIRYQTPETLGNDRLALCAAACERFPNQAVMIIDFGTAITYDVLNSKHEYLGGL
ILAGTSLSARALNEHTAQLPAIGLQKESGIIGRNTRDCLSKGLFWGTVAQTEGLILKLKSELAEEHGEPEVKVLITGGNS
VTLAGAMPHIDIRDEFAIHKGIRFIAALNTNR

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 29840; Mature: 29708

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRNHLVKQPNLSSIATVDIGNTQTSIAIFEGDELKEFERFSSKNLESKSALPDFCQKC
CCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCHHHHHHH
QSLVGSAPLIAMSSVVPNVASALKTMFHQQFSEKPIFEITYQTKLPFHIRYQTPETLGND
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEECCHHHCCCC
RLALCAAACERFPNQAVMIIDFGTAITYDVLNSKHEYLGGLILAGTSLSARALNEHTAQL
HHHHHHHHHHHCCCCEEEEEECCCEEEHHHHCCCHHHHCEEEEECCCCHHHHHHHHHHHC
PAIGLQKESGIIGRNTRDCLSKGLFWGTVAQTEGLILKLKSELAEEHGEPEVKVLITGGN
CCCCCCCCCCCCCCCHHHHHHCCCEEEEHHCCCCEEEEEHHHHHHHCCCCEEEEEEECCC
SVTLAGAMPHIDIRDEFAIHKGIRFIAALNTNR
EEEEECCCCCCCCCHHHHHHHCEEEEEEECCCC
>Mature Secondary Structure 
TPRNHLVKQPNLSSIATVDIGNTQTSIAIFEGDELKEFERFSSKNLESKSALPDFCQKC
CCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCHHHHHHH
QSLVGSAPLIAMSSVVPNVASALKTMFHQQFSEKPIFEITYQTKLPFHIRYQTPETLGND
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEECCHHHCCCC
RLALCAAACERFPNQAVMIIDFGTAITYDVLNSKHEYLGGLILAGTSLSARALNEHTAQL
HHHHHHHHHHHCCCCEEEEEECCCEEEHHHHCCCHHHHCEEEEECCCCHHHHHHHHHHHC
PAIGLQKESGIIGRNTRDCLSKGLFWGTVAQTEGLILKLKSELAEEHGEPEVKVLITGGN
CCCCCCCCCCCCCCCHHHHHHCCCEEEEHHCCCCEEEEEHHHHHHHCCCCEEEEEEECCC
SVTLAGAMPHIDIRDEFAIHKGIRFIAALNTNR
EEEEECCCCCCCCCHHHHHHHCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]