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The map label for this gene is mtnA [H]

Identifier: 193214358

GI number: 193214358

Start: 751394

End: 752494

Strand: Direct

Name: mtnA [H]

Synonym: Ctha_0640

Alternate gene names: 193214358

Gene position: 751394-752494 (Clockwise)

Preceding gene: 193214349

Following gene: 193214359

Centisome position: 22.81

GC content: 47.05

Gene sequence:

>1101_bases
ATGATTGACGCAATATCCTTCGGAAATAACAAGCTGAGATATCTCGATCAGAGATTTCTTCCATTACAAGAAAATTATGT
AGAAACCGCTGACTACTTACAGGCGATTGAAGCCATTAAAACGCTCGCCGTGCGCGGTGCACCGCTGATCGGTGTTGCTG
CTGGCTACACGGTTGTTTTGGCAGTGCAATGCTTCGATGGCGAAAAAGATAGCTTCAAAGCGTACTTCGATAAAATTATT
GCTGAAGTTGAAGCCTCAAGACCGACTGCGGTGAACTTGTTTTTTGCAACCGCAAAAATGAACGAAGTTGTTGCCAAACG
CTTTGCGGAATCCAGCATGGCCGAGCTCAAAGAGCACATTCTGAACGAAGCGATTTGCATCCACAACGAGGAAATCGCAA
ACTGCGAAAATATGGCTCGTCATGGCGTGGCACTTATCCAAAAAGATCTTGGCCACATTTTGGAAAAGCGCAAGCTAAAT
GTTTTAACCCACTGCAACACGGGCACGCTTGCCACTGGCGGACTTGGCACCGCACTTGGCGTTATCAAACAAGCTTACAA
AGACGGCCTAATTGAAAAAGTTTATACTTCTGAAAGTCGCCCACTTTTGCAAGGCCTTCGCCTAACGGCTTGGGAACTTG
AAAAAGAAGGCATACCATTCTTTTCACATGCCGATTCATCTTCTGGCATTTTGATGCAGCGCGGCATGGTCGATTTTGGC
ATTGTTGGCGCTGATCGCATCGCAGCCAATGGCGACACGGCAAACAAAATCGGAACATTCAACCACGCCGTGCTTTGCCA
CGAGCATGGATTGCCGTTCTATATCGCTGCTCCGATTTCTACCGTTGATATTACCATTCCTGATGGCACTTATATTCCAA
TTGAAGAAAGAAACGCCGATGAACTTCGCGCGATTCATGGAACCAAAGTTGCCACAGACACCACGCCAGTTGTGAATTTC
GCGTTCGACATGACACCAGCCAAATACATCAATGGCATTATTACCGATAAAGCCGCACTGACTGGCGACTATGTCAAAGC
GCTAAAAGAAGTTGTTCCAGCCGCTGCAGCTTCCGACAAAGGCCTTTCCAGCGTTTGCTAA

Upstream 100 bases:

>100_bases
GGTTTTTCGCCCTCATGTTGCTTTTGTAAATTCCTCCCCGACTTTCAGTTTAAGTCTCAGTTACCAAATTTTTTAACGGC
TTTGAAACAAAAAACCGATA

Downstream 100 bases:

>100_bases
TTCCATAGCCGATTCTCATTTTTTTGAAGCACAATCGACATAGGGCGAGAAATGTTCTCGCCCTATTTTTTTACTTGCAA
GACGTGCAAGTTCCTCAATC

Product: translation initiation factor, aIF-2BI family

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MIDAISFGNNKLRYLDQRFLPLQENYVETADYLQAIEAIKTLAVRGAPLIGVAAGYTVVLAVQCFDGEKDSFKAYFDKII
AEVEASRPTAVNLFFATAKMNEVVAKRFAESSMAELKEHILNEAICIHNEEIANCENMARHGVALIQKDLGHILEKRKLN
VLTHCNTGTLATGGLGTALGVIKQAYKDGLIEKVYTSESRPLLQGLRLTAWELEKEGIPFFSHADSSSGILMQRGMVDFG
IVGADRIAANGDTANKIGTFNHAVLCHEHGLPFYIAAPISTVDITIPDGTYIPIEERNADELRAIHGTKVATDTTPVVNF
AFDMTPAKYINGIITDKAALTGDYVKALKEVVPAAAASDKGLSSVC

Sequences:

>Translated_366_residues
MIDAISFGNNKLRYLDQRFLPLQENYVETADYLQAIEAIKTLAVRGAPLIGVAAGYTVVLAVQCFDGEKDSFKAYFDKII
AEVEASRPTAVNLFFATAKMNEVVAKRFAESSMAELKEHILNEAICIHNEEIANCENMARHGVALIQKDLGHILEKRKLN
VLTHCNTGTLATGGLGTALGVIKQAYKDGLIEKVYTSESRPLLQGLRLTAWELEKEGIPFFSHADSSSGILMQRGMVDFG
IVGADRIAANGDTANKIGTFNHAVLCHEHGLPFYIAAPISTVDITIPDGTYIPIEERNADELRAIHGTKVATDTTPVVNF
AFDMTPAKYINGIITDKAALTGDYVKALKEVVPAAAASDKGLSSVC
>Mature_366_residues
MIDAISFGNNKLRYLDQRFLPLQENYVETADYLQAIEAIKTLAVRGAPLIGVAAGYTVVLAVQCFDGEKDSFKAYFDKII
AEVEASRPTAVNLFFATAKMNEVVAKRFAESSMAELKEHILNEAICIHNEEIANCENMARHGVALIQKDLGHILEKRKLN
VLTHCNTGTLATGGLGTALGVIKQAYKDGLIEKVYTSESRPLLQGLRLTAWELEKEGIPFFSHADSSSGILMQRGMVDFG
IVGADRIAANGDTANKIGTFNHAVLCHEHGLPFYIAAPISTVDITIPDGTYIPIEERNADELRAIHGTKVATDTTPVVNF
AFDMTPAKYINGIITDKAALTGDYVKALKEVVPAAAASDKGLSSVC

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=345, Percent_Identity=38.5507246376812, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI23943880, Length=338, Percent_Identity=34.3195266272189, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17557462, Length=340, Percent_Identity=35.8823529411765, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6325375, Length=391, Percent_Identity=32.2250639386189, Blast_Score=176, Evalue=5e-45,
Organism=Drosophila melanogaster, GI21357667, Length=344, Percent_Identity=35.4651162790698, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24651647, Length=344, Percent_Identity=35.4651162790698, Blast_Score=207, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 39663; Mature: 39663

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDAISFGNNKLRYLDQRFLPLQENYVETADYLQAIEAIKTLAVRGAPLIGVAAGYTVVL
CCCCEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEE
AVQCFDGEKDSFKAYFDKIIAEVEASRPTAVNLFFATAKMNEVVAKRFAESSMAELKEHI
EEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
LNEAICIHNEEIANCENMARHGVALIQKDLGHILEKRKLNVLTHCNTGTLATGGLGTALG
HHHHHEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCHHHHHH
VIKQAYKDGLIEKVYTSESRPLLQGLRLTAWELEKEGIPFFSHADSSSGILMQRGMVDFG
HHHHHHHHHHHHHHHCCCCCHHHHCCHHHEEEHHHCCCCEEECCCCCCCEEEECCCCCEE
IVGADRIAANGDTANKIGTFNHAVLCHEHGLPFYIAAPISTVDITIPDGTYIPIEERNAD
ECCCCCEECCCCCCCCCCCCCEEEEEECCCCCEEEECCCCEEEEECCCCCEEECCCCCHH
ELRAIHGTKVATDTTPVVNFAFDMTPAKYINGIITDKAALTGDYVKALKEVVPAAAASDK
HHHHHCCCEEECCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
GLSSVC
CCCCCC
>Mature Secondary Structure
MIDAISFGNNKLRYLDQRFLPLQENYVETADYLQAIEAIKTLAVRGAPLIGVAAGYTVVL
CCCCEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEE
AVQCFDGEKDSFKAYFDKIIAEVEASRPTAVNLFFATAKMNEVVAKRFAESSMAELKEHI
EEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
LNEAICIHNEEIANCENMARHGVALIQKDLGHILEKRKLNVLTHCNTGTLATGGLGTALG
HHHHHEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCHHHHHH
VIKQAYKDGLIEKVYTSESRPLLQGLRLTAWELEKEGIPFFSHADSSSGILMQRGMVDFG
HHHHHHHHHHHHHHHCCCCCHHHHCCHHHEEEHHHCCCCEEECCCCCCCEEEECCCCCEE
IVGADRIAANGDTANKIGTFNHAVLCHEHGLPFYIAAPISTVDITIPDGTYIPIEERNAD
ECCCCCEECCCCCCCCCCCCCEEEEEECCCCCEEEECCCCEEEEECCCCCEEECCCCCHH
ELRAIHGTKVATDTTPVVNFAFDMTPAKYINGIITDKAALTGDYVKALKEVVPAAAASDK
HHHHHCCCEEECCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
GLSSVC
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]