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The map label for this gene is pyrK [H]

Identifier: 193214014

GI number: 193214014

Start: 335899

End: 336717

Strand: Direct

Name: pyrK [H]

Synonym: Ctha_0295

Alternate gene names: 193214014

Gene position: 335899-336717 (Clockwise)

Preceding gene: 193214013

Following gene: 193214018

Centisome position: 10.2

GC content: 48.84

Gene sequence:

>819_bases
ATGACACACATGACTGAAGCCACGACCAAAGCTGATGATATTTTTGACCTCTCACTAACCGTTCAAGAAACCACCCAACT
CAATGCAACAACTGCCGTTCTTGCATTCAAATCTGAGTTAATTGCGCCGCTCATCAAGCCGGGGCAGTTTGTAAATATTA
AAGTGAACGATACGCTTGCGCCACTTTTGCGAAGGCCGCTCAGTGTGCATCGCGTAGAAGGCGACATTTTTGAAGTCATG
GTAAAAGTGGTGGGTTCTGGCACAAAACTGCTCTACAATGCGCTGCCCGGCTCAACCGTACAGGTTTTGGGGCCGCTTGG
CAATTCGTTTGATTACGCTCGCCAGGATTACGATACAGCCATTTTGGTTTCCGGCGGCGTTGGGGTTGCGCCCATGACCA
TTCTCGACGATTGCTTGCGCCAAGCAGGAAAAGAAATTTTCAATTATGTGGGCGGTCGCACGGCTTCCGACATCATCGCC
AGAAAACTTACGAACCTGCGCATCGCAACCGATGATGGCTCACAAGGTTTTAAAGGAACGGTGGTCGCGCTGCTCGAACA
GGACTTTCCAGAATTTGCTAAAAAACGGGTTCGGATTTTTTCCTGTGGCCCAAATAGAATGCTTCAAGCTCTCGCTGATT
TTAGCATGAAAAAAAATATCCCATGCGAGGTTTCTTTAGAATCCGTGATGGGTTGCGGCATTGGCATTTGTTACGGCTGC
CCCGTTCATGTCAAAAATGAACAAGGCGAACCCGACGGCCACAAACTGCTTTGCCAACACGGCCCAGTTATGGACGCCAA
GCAAGTTGTGTTTGAGTAA

Upstream 100 bases:

>100_bases
CAAAGGCAAATGGAGTGCAACCAGAATTACAAAAAATGATTAAATTCGCCGGCAATCGAGCCGATTCTGTGCAACACAAT
CCCGAAAAGCAAAATTTAGA

Downstream 100 bases:

>100_bases
AACGCTGAAGGAAAAGCGCTTGTCACTCAGCAGAAAGTAAGTCTTCCCCCAAAGACGCATTTATCCAACAGGCGTCGTTT
CAGCTAATCGCTCTGCGATG

Product: oxidoreductase FAD/NAD(P)-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTHMTEATTKADDIFDLSLTVQETTQLNATTAVLAFKSELIAPLIKPGQFVNIKVNDTLAPLLRRPLSVHRVEGDIFEVM
VKVVGSGTKLLYNALPGSTVQVLGPLGNSFDYARQDYDTAILVSGGVGVAPMTILDDCLRQAGKEIFNYVGGRTASDIIA
RKLTNLRIATDDGSQGFKGTVVALLEQDFPEFAKKRVRIFSCGPNRMLQALADFSMKKNIPCEVSLESVMGCGIGICYGC
PVHVKNEQGEPDGHKLLCQHGPVMDAKQVVFE

Sequences:

>Translated_272_residues
MTHMTEATTKADDIFDLSLTVQETTQLNATTAVLAFKSELIAPLIKPGQFVNIKVNDTLAPLLRRPLSVHRVEGDIFEVM
VKVVGSGTKLLYNALPGSTVQVLGPLGNSFDYARQDYDTAILVSGGVGVAPMTILDDCLRQAGKEIFNYVGGRTASDIIA
RKLTNLRIATDDGSQGFKGTVVALLEQDFPEFAKKRVRIFSCGPNRMLQALADFSMKKNIPCEVSLESVMGCGIGICYGC
PVHVKNEQGEPDGHKLLCQHGPVMDAKQVVFE
>Mature_271_residues
THMTEATTKADDIFDLSLTVQETTQLNATTAVLAFKSELIAPLIKPGQFVNIKVNDTLAPLLRRPLSVHRVEGDIFEVMV
KVVGSGTKLLYNALPGSTVQVLGPLGNSFDYARQDYDTAILVSGGVGVAPMTILDDCLRQAGKEIFNYVGGRTASDIIAR
KLTNLRIATDDGSQGFKGTVVALLEQDFPEFAKKRVRIFSCGPNRMLQALADFSMKKNIPCEVSLESVMGCGIGICYGCP
VHVKNEQGEPDGHKLLCQHGPVMDAKQVVFE

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 29475; Mature: 29344

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHMTEATTKADDIFDLSLTVQETTQLNATTAVLAFKSELIAPLIKPGQFVNIKVNDTLA
CCCCCCCCCCCCCEEEEEEEEEHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHH
PLLRRPLSVHRVEGDIFEVMVKVVGSGTKLLYNALPGSTVQVLGPLGNSFDYARQDYDTA
HHHHCCCHHHHCCHHHHHHHHHHHCCCHHEEEECCCCCEEEEEECCCCCHHHHHHCCCEE
ILVSGGVGVAPMTILDDCLRQAGKEIFNYVGGRTASDIIARKLTNLRIATDDGSQGFKGT
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEECCCCCCCCHH
VVALLEQDFPEFAKKRVRIFSCGPNRMLQALADFSMKKNIPCEVSLESVMGCGIGICYGC
HHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCEEECC
PVHVKNEQGEPDGHKLLCQHGPVMDAKQVVFE
EEEEECCCCCCCCCEEEECCCCCCCHHHHHCC
>Mature Secondary Structure 
THMTEATTKADDIFDLSLTVQETTQLNATTAVLAFKSELIAPLIKPGQFVNIKVNDTLA
CCCCCCCCCCCCEEEEEEEEEHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHH
PLLRRPLSVHRVEGDIFEVMVKVVGSGTKLLYNALPGSTVQVLGPLGNSFDYARQDYDTA
HHHHCCCHHHHCCHHHHHHHHHHHCCCHHEEEECCCCCEEEEEECCCCCHHHHHHCCCEE
ILVSGGVGVAPMTILDDCLRQAGKEIFNYVGGRTASDIIARKLTNLRIATDDGSQGFKGT
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEECCCCCCCCHH
VVALLEQDFPEFAKKRVRIFSCGPNRMLQALADFSMKKNIPCEVSLESVMGCGIGICYGC
HHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCEEECC
PVHVKNEQGEPDGHKLLCQHGPVMDAKQVVFE
EEEEECCCCCCCCCEEEECCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA