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The map label for this gene is murB [H]

Identifier: 193212594

GI number: 193212594

Start: 1028197

End: 1029786

Strand: Direct

Name: murB [H]

Synonym: Cpar_0937

Alternate gene names: 193212594

Gene position: 1028197-1029786 (Clockwise)

Preceding gene: 193212593

Following gene: 193212607

Centisome position: 44.91

GC content: 60.31

Gene sequence:

>1590_bases
ATGAACACCGCTCCATTTGCCTGCCCGTTCCGTGAACATGTTGATCTTTCGACGGTAGGCTACTACGCGATCGGCGGAGA
GGCCAGATGGCTGCTTTTGCCTCGAACCGTTGCGGAACTTGCCGCCGCTCTTGCGCAGTGCCGTCAGCATGCGATTCCGG
TGATCATTGCAGGAAAGGGCACCAACATGCTTTTTTCGGATGAGCATTTTCCGGGAGCGGTGATTTTGCTTGAATCGATG
AAGCGCATCATCCAGCTTTCAGAAAGCCTCTTTTTCTGCGAAGCGGGGGCTGAGAATAGTGATGTCGCCCTGCGGCTCCA
GCAGGCGGGGAGAACAGATGGAGAGTGGCTTTACCGGCTTCCAGGCACCATTGGCGCCACGGTGCGCATGAACGGGCGTT
GCTACGGTCAAGAAGTTTCTGCTGTAACCCGGAGTGTGGTGACGGTCGGGCTTGACGGTACGGTTTGCTTTCGGGAAGGC
TGCGAGGTGTTTCTCGGTTACAAGCACACCAGCCTGATGCAGAGTCCCGAGATCGTCGTCGGAGCGCTGCTCGAATTCGA
CAGCGAGGACGATCCAGAGGCGATCGGAAGGCGAATGCAGGAGTATTCGGATGACCGCGAGGCGAAGCACCAGTTTGATT
ATCCAAGCTGCGGCTCGACCTTCAAGAACAGCTATGAAGCCGGACAGCCGAGCGGGCAGATTTTCGACGCTCTCGGCTTC
AGGCGGCGGCGCGAGGCTGGGGCGCAGGTTAGCGAGCACCACGCCAACTTCATCTTCAACACCGGCGGCGCGAAAGCTGT
CGATGTACTTCGCCTTGCCGCAGCCATGCGCACCGCCGCCAGGGAGCAGGTTGGAGCTAATCTCGACCTCGAATTGCACT
GCGCCGGCCTTTTCGAGATGGCGTTGCTCGACCAGTGCGGCATCGCCTCGACGCCAGAGCCATCACGCCCCGGTTACGGC
TGGACTGGCCTCTTGCGCTTTCCGGATTTCGGGGCGGCGGTGTTCCCCCGAACGCTCCTCCACGGTCCGATGCTCGGTTA
CGCTTGTACCGATGCGGAATTTCCGTTCGGCATCACAGTGAGGGTCGAGCAGCTTGCGTCGCTCGAAGAGGCTCGGCGTG
CGCCCGAAAAACCCTTTATCCGCTGGACGACTCGCGACGAGAGCGGCACAGCTTTTCCGCTTCGACCCGATGCTCCGGCA
GGCGCATTCGTTGATCGCTTGTGGGCATTCAGCGTCTCGGAGCTTTTCATTGGTGGTAGAGATGGGGAAGGCTATCTCGA
ATTCGAGTTAACGCCCGAAGGCCACTGGGTAGCGCTTCGTTTCGACGCCCCGCGCCACCGCGCCGCCGGGCACGAAACGC
CTTCGGAAGCGCTGTGGCTAGGCAAGGTGCAGCCGTTTGCTGGTGACCAAGGCTTCGGCATGGAGCTCAGTTACGAAATG
CTCGAACCCTTTATTCGTGATGGTTCCTTGCACCTGCAATGCGCTGCTAGCCTCGGAGGCGGGCGCTACGGCCTGTTCCC
GTGGTGGTGCGACGAAGGCAAGCCCGATTTCCACCAGCCAGGCCGGTTCTGCGAGTTGGCGTTGGCGTGA

Upstream 100 bases:

>100_bases
TCCTTCTGTTGGTTCCGGCGTCCTTTTCCTTTTTGTCTGAATCGTTCCTACCTTTGACTTTGTTGTCGATTGCGCCAATC
CTCCCAAGTATTCAGGCCTT

Downstream 100 bases:

>100_bases
GTTCGTAGGGGCGGGTTTTACACCCGCCCATCAAATACAACAAATTCGCTCATGCGCAGAATATGAAGCGGCTTGTTTGC
TTTCAGACCAGCACCATTCC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MNTAPFACPFREHVDLSTVGYYAIGGEARWLLLPRTVAELAAALAQCRQHAIPVIIAGKGTNMLFSDEHFPGAVILLESM
KRIIQLSESLFFCEAGAENSDVALRLQQAGRTDGEWLYRLPGTIGATVRMNGRCYGQEVSAVTRSVVTVGLDGTVCFREG
CEVFLGYKHTSLMQSPEIVVGALLEFDSEDDPEAIGRRMQEYSDDREAKHQFDYPSCGSTFKNSYEAGQPSGQIFDALGF
RRRREAGAQVSEHHANFIFNTGGAKAVDVLRLAAAMRTAAREQVGANLDLELHCAGLFEMALLDQCGIASTPEPSRPGYG
WTGLLRFPDFGAAVFPRTLLHGPMLGYACTDAEFPFGITVRVEQLASLEEARRAPEKPFIRWTTRDESGTAFPLRPDAPA
GAFVDRLWAFSVSELFIGGRDGEGYLEFELTPEGHWVALRFDAPRHRAAGHETPSEALWLGKVQPFAGDQGFGMELSYEM
LEPFIRDGSLHLQCAASLGGGRYGLFPWWCDEGKPDFHQPGRFCELALA

Sequences:

>Translated_529_residues
MNTAPFACPFREHVDLSTVGYYAIGGEARWLLLPRTVAELAAALAQCRQHAIPVIIAGKGTNMLFSDEHFPGAVILLESM
KRIIQLSESLFFCEAGAENSDVALRLQQAGRTDGEWLYRLPGTIGATVRMNGRCYGQEVSAVTRSVVTVGLDGTVCFREG
CEVFLGYKHTSLMQSPEIVVGALLEFDSEDDPEAIGRRMQEYSDDREAKHQFDYPSCGSTFKNSYEAGQPSGQIFDALGF
RRRREAGAQVSEHHANFIFNTGGAKAVDVLRLAAAMRTAAREQVGANLDLELHCAGLFEMALLDQCGIASTPEPSRPGYG
WTGLLRFPDFGAAVFPRTLLHGPMLGYACTDAEFPFGITVRVEQLASLEEARRAPEKPFIRWTTRDESGTAFPLRPDAPA
GAFVDRLWAFSVSELFIGGRDGEGYLEFELTPEGHWVALRFDAPRHRAAGHETPSEALWLGKVQPFAGDQGFGMELSYEM
LEPFIRDGSLHLQCAASLGGGRYGLFPWWCDEGKPDFHQPGRFCELALA
>Mature_529_residues
MNTAPFACPFREHVDLSTVGYYAIGGEARWLLLPRTVAELAAALAQCRQHAIPVIIAGKGTNMLFSDEHFPGAVILLESM
KRIIQLSESLFFCEAGAENSDVALRLQQAGRTDGEWLYRLPGTIGATVRMNGRCYGQEVSAVTRSVVTVGLDGTVCFREG
CEVFLGYKHTSLMQSPEIVVGALLEFDSEDDPEAIGRRMQEYSDDREAKHQFDYPSCGSTFKNSYEAGQPSGQIFDALGF
RRRREAGAQVSEHHANFIFNTGGAKAVDVLRLAAAMRTAAREQVGANLDLELHCAGLFEMALLDQCGIASTPEPSRPGYG
WTGLLRFPDFGAAVFPRTLLHGPMLGYACTDAEFPFGITVRVEQLASLEEARRAPEKPFIRWTTRDESGTAFPLRPDAPA
GAFVDRLWAFSVSELFIGGRDGEGYLEFELTPEGHWVALRFDAPRHRAAGHETPSEALWLGKVQPFAGDQGFGMELSYEM
LEPFIRDGSLHLQCAASLGGGRYGLFPWWCDEGKPDFHQPGRFCELALA

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 58167; Mature: 58167

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAPFACPFREHVDLSTVGYYAIGGEARWLLLPRTVAELAAALAQCRQHAIPVIIAGKG
CCCCCCCCCHHHCCCEECCEEEEECCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCC
TNMLFSDEHFPGAVILLESMKRIIQLSESLFFCEAGAENSDVALRLQQAGRTDGEWLYRL
CCEEECCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEEEHHCCCCCCCEEEEC
PGTIGATVRMNGRCYGQEVSAVTRSVVTVGLDGTVCFREGCEVFLGYKHTSLMQSPEIVV
CCCEEEEEEECCEECCHHHHHHHHHHEEECCCCEEEHHCCCEEEECCCHHHHHCCCHHHH
GALLEFDSEDDPEAIGRRMQEYSDDREAKHQFDYPSCGSTFKNSYEAGQPSGQIFDALGF
HHHHHCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHCCCCCCCCCCHHHHHHHH
RRRREAGAQVSEHHANFIFNTGGAKAVDVLRLAAAMRTAAREQVGANLDLELHCAGLFEM
HHHHHHCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
ALLDQCGIASTPEPSRPGYGWTGLLRFPDFGAAVFPRTLLHGPMLGYACTDAEFPFGITV
HHHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEECCCCCCCEEEE
RVEQLASLEEARRAPEKPFIRWTTRDESGTAFPLRPDAPAGAFVDRLWAFSVSELFIGGR
EHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCHHHHHHHHHHHHHHHEEECC
DGEGYLEFELTPEGHWVALRFDAPRHRAAGHETPSEALWLGKVQPFAGDQGFGMELSYEM
CCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEHHH
LEPFIRDGSLHLQCAASLGGGRYGLFPWWCDEGKPDFHQPGRFCELALA
HHHHHHCCCEEEEEEEECCCCEECCCEEECCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MNTAPFACPFREHVDLSTVGYYAIGGEARWLLLPRTVAELAAALAQCRQHAIPVIIAGKG
CCCCCCCCCHHHCCCEECCEEEEECCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCC
TNMLFSDEHFPGAVILLESMKRIIQLSESLFFCEAGAENSDVALRLQQAGRTDGEWLYRL
CCEEECCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEEEHHCCCCCCCEEEEC
PGTIGATVRMNGRCYGQEVSAVTRSVVTVGLDGTVCFREGCEVFLGYKHTSLMQSPEIVV
CCCEEEEEEECCEECCHHHHHHHHHHEEECCCCEEEHHCCCEEEECCCHHHHHCCCHHHH
GALLEFDSEDDPEAIGRRMQEYSDDREAKHQFDYPSCGSTFKNSYEAGQPSGQIFDALGF
HHHHHCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHCCCCCCCCCCHHHHHHHH
RRRREAGAQVSEHHANFIFNTGGAKAVDVLRLAAAMRTAAREQVGANLDLELHCAGLFEM
HHHHHHCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
ALLDQCGIASTPEPSRPGYGWTGLLRFPDFGAAVFPRTLLHGPMLGYACTDAEFPFGITV
HHHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEECCCCCCCEEEE
RVEQLASLEEARRAPEKPFIRWTTRDESGTAFPLRPDAPAGAFVDRLWAFSVSELFIGGR
EHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCHHHHHHHHHHHHHHHEEECC
DGEGYLEFELTPEGHWVALRFDAPRHRAAGHETPSEALWLGKVQPFAGDQGFGMELSYEM
CCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEHHH
LEPFIRDGSLHLQCAASLGGGRYGLFPWWCDEGKPDFHQPGRFCELALA
HHHHHHCCCEEEEEEEECCCCEECCCEEECCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA