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The map label for this gene is mocR [H]

Identifier: 192291512

GI number: 192291512

Start: 3382677

End: 3384167

Strand: Reverse

Name: mocR [H]

Synonym: Rpal_3136

Alternate gene names: 192291512

Gene position: 3384167-3382677 (Counterclockwise)

Preceding gene: 192291515

Following gene: 192291511

Centisome position: 58.92

GC content: 66.13

Gene sequence:

>1491_bases
TTGTTCAAGCACTCGCAGCTCGAATCCGTCAAAGCCTGGGTGGCGCATCCGGCGCACGCGGCGATGCCGTTACACGCACG
GGTTCAGCGTGCCATCCGCCAACTGATCGTCGACGGTGCGCTGGGTGCAGGCAAGCCGCTGCCCGCCTCGCGTGCGCTTG
CTCAATCGCTTGGCGTGTCGCGCGATACGATCGAGGTCGCCTATGGTCAGCTCCATGCTGAGGGCTTCATCGAGCGGCGT
GTGGGCAGCGGTAGCTTCGTCGCGGAGATGACGGAATTCGCGCCGGGCCGCCGCCTGTCGCAGCGCGACGCGCTGCTCCG
CAGCCAGGCGCCGAAGCTCAGCAAGCGCGGGACCGCGATGTTCGGCAGCGGCGGCATTCGCGAGCAGTTGTTGCCGAGGC
CGTTCGTCCACGGTGTGCCGGAAACGCGGACGTTTCCGCTTCCGCTGTGGGAGCGACTGGAACGCCAAGTCCGCAAGGAG
CTTGGCGCGCAGACCCTGCTACACTGCGATCCGCAGGGCACCGAGCCGCTACGCCGCGCCATTGCCGACTACGTCAACCT
CGAACGCGGCGCCCGCGCCGCGGCGGACCGGGTTCTGGTGCTCACCAGTTCGCAGCAGGCGCTGTCGCTGTGCGCGAATA
TGCTGCTCGATCCCGGCGATCGTGTCTTCATCGAAGATCCAGCCTATTACGGCGCGCGCAAAGCGTTCGATGCCGCAGGT
CTGGAGTGCGTTCCGATTCCGGTCGACCGTCAGGGCCTCGTCGTCGACCAGATCACGGCCCAGCCGCGCCGGGCCAAGGC
GGTGTTCCTCACGCCCTCTCACCAGTTTCCGACCGGCGCGACGCTGGCGCTGGATCGCCGCCTCGCATTGATCGAATGGG
CGGCGCGACATCAGACCTGGATCATCGAAGACGATTACGACAGCGAATTCCACTACGCCGGCAAGCCGACGGCTTGCGTG
CAAGGTCTCGATCCGCACGACCGGACCGTCTACATTGGGACCTTCACCAAATCGCTGTTTCCGGGCTTGAGGATCGGCTA
CGTCGTCTTGCCGCCGCAGCTCGTGAAGCCGATGACGGTCGCGCGCACGCTGCTGGATGGTCACAGCGCCTCGATGGCGC
AACTGACGCTGGCCCGGTTCATGGAGGGCGGACATTTCGGCGCGCATGTTCGCACGATGCGCGGCGTCTATGCGCAGCGC
CTGGATGTCCTCGTCCGCCTCGTCCGCAAATATCTGTCTGGATTGGTCGAGCCGCGCGTTCCGGTCGGCGGCCTGCAACT
GCCCTGCGTACTGACCTGCGACCTTGCGGAGCGTACCGCCGTCGACGCCGCGCAGCGTGTCGGGATCGAGTTGCTCGGTC
TGTCTGGATTGCAGCACGCGCGCCACGGGGAGGCCGGCTTCCTGATGGGCTTTGCTGCGTACACGCCGCTCGAGATCGAA
GGCGCCGTGAAGAAGCTGGCCAAAGCGCTTCGGGCGGCTGCGAAATCATAA

Upstream 100 bases:

>100_bases
ACAATCTTCTGCTGGGGCGAGGCGAGAGATGGATGGATTGACATTTAGCCGCCCGGTGGCCTGATATGCCCCTCCATTAT
CCGCCCCAAAGGCAGACCAT

Downstream 100 bases:

>100_bases
GCCGGCGCCGCGTCTAGCTGCGATCAATTGGTTGGGTATTGGTGCCGGAAGTGGAGGGGATAACCAGACCACGCCCGTGC
TAGATCCTGGTGACCGACGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MFKHSQLESVKAWVAHPAHAAMPLHARVQRAIRQLIVDGALGAGKPLPASRALAQSLGVSRDTIEVAYGQLHAEGFIERR
VGSGSFVAEMTEFAPGRRLSQRDALLRSQAPKLSKRGTAMFGSGGIREQLLPRPFVHGVPETRTFPLPLWERLERQVRKE
LGAQTLLHCDPQGTEPLRRAIADYVNLERGARAAADRVLVLTSSQQALSLCANMLLDPGDRVFIEDPAYYGARKAFDAAG
LECVPIPVDRQGLVVDQITAQPRRAKAVFLTPSHQFPTGATLALDRRLALIEWAARHQTWIIEDDYDSEFHYAGKPTACV
QGLDPHDRTVYIGTFTKSLFPGLRIGYVVLPPQLVKPMTVARTLLDGHSASMAQLTLARFMEGGHFGAHVRTMRGVYAQR
LDVLVRLVRKYLSGLVEPRVPVGGLQLPCVLTCDLAERTAVDAAQRVGIELLGLSGLQHARHGEAGFLMGFAAYTPLEIE
GAVKKLAKALRAAAKS

Sequences:

>Translated_496_residues
MFKHSQLESVKAWVAHPAHAAMPLHARVQRAIRQLIVDGALGAGKPLPASRALAQSLGVSRDTIEVAYGQLHAEGFIERR
VGSGSFVAEMTEFAPGRRLSQRDALLRSQAPKLSKRGTAMFGSGGIREQLLPRPFVHGVPETRTFPLPLWERLERQVRKE
LGAQTLLHCDPQGTEPLRRAIADYVNLERGARAAADRVLVLTSSQQALSLCANMLLDPGDRVFIEDPAYYGARKAFDAAG
LECVPIPVDRQGLVVDQITAQPRRAKAVFLTPSHQFPTGATLALDRRLALIEWAARHQTWIIEDDYDSEFHYAGKPTACV
QGLDPHDRTVYIGTFTKSLFPGLRIGYVVLPPQLVKPMTVARTLLDGHSASMAQLTLARFMEGGHFGAHVRTMRGVYAQR
LDVLVRLVRKYLSGLVEPRVPVGGLQLPCVLTCDLAERTAVDAAQRVGIELLGLSGLQHARHGEAGFLMGFAAYTPLEIE
GAVKKLAKALRAAAKS
>Mature_496_residues
MFKHSQLESVKAWVAHPAHAAMPLHARVQRAIRQLIVDGALGAGKPLPASRALAQSLGVSRDTIEVAYGQLHAEGFIERR
VGSGSFVAEMTEFAPGRRLSQRDALLRSQAPKLSKRGTAMFGSGGIREQLLPRPFVHGVPETRTFPLPLWERLERQVRKE
LGAQTLLHCDPQGTEPLRRAIADYVNLERGARAAADRVLVLTSSQQALSLCANMLLDPGDRVFIEDPAYYGARKAFDAAG
LECVPIPVDRQGLVVDQITAQPRRAKAVFLTPSHQFPTGATLALDRRLALIEWAARHQTWIIEDDYDSEFHYAGKPTACV
QGLDPHDRTVYIGTFTKSLFPGLRIGYVVLPPQLVKPMTVARTLLDGHSASMAQLTLARFMEGGHFGAHVRTMRGVYAQR
LDVLVRLVRKYLSGLVEPRVPVGGLQLPCVLTCDLAERTAVDAAQRVGIELLGLSGLQHARHGEAGFLMGFAAYTPLEIE
GAVKKLAKALRAAAKS

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=314, Percent_Identity=25.1592356687898, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI33469970, Length=314, Percent_Identity=25.1592356687898, Blast_Score=106, Evalue=6e-23,
Organism=Escherichia coli, GI1790797, Length=400, Percent_Identity=28, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1787710, Length=401, Percent_Identity=26.6832917705736, Blast_Score=131, Evalue=8e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54213; Mature: 54213

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKHSQLESVKAWVAHPAHAAMPLHARVQRAIRQLIVDGALGAGKPLPASRALAQSLGVS
CCCCHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
RDTIEVAYGQLHAEGFIERRVGSGSFVAEMTEFAPGRRLSQRDALLRSQAPKLSKRGTAM
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHCCCEE
FGSGGIREQLLPRPFVHGVPETRTFPLPLWERLERQVRKELGAQTLLHCDPQGTEPLRRA
ECCCCCHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHH
IADYVNLERGARAAADRVLVLTSSQQALSLCANMLLDPGDRVFIEDPAYYGARKAFDAAG
HHHHHHHHHCCHHHHCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHCHHHHHHCCC
LECVPIPVDRQGLVVDQITAQPRRAKAVFLTPSHQFPTGATLALDRRLALIEWAARHQTW
CEEEECCCCCCCCEEHHHCCCCCCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHCCEE
IIEDDYDSEFHYAGKPTACVQGLDPHDRTVYIGTFTKSLFPGLRIGYVVLPPQLVKPMTV
EEECCCCCCCEECCCCHHHHCCCCCCCCEEEEEECHHHHCCCCEEEEEEECHHHHHHHHH
ARTLLDGHSASMAQLTLARFMEGGHFGAHVRTMRGVYAQRLDVLVRLVRKYLSGLVEPRV
HHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVGGLQLPCVLTCDLAERTAVDAAQRVGIELLGLSGLQHARHGEAGFLMGFAAYTPLEIE
CCCCCCCCEEEEECCHHHHHHHHHHHCCEEEECCCCHHHHCCCCCCEEEHHHHCCCEEHH
GAVKKLAKALRAAAKS
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFKHSQLESVKAWVAHPAHAAMPLHARVQRAIRQLIVDGALGAGKPLPASRALAQSLGVS
CCCCHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
RDTIEVAYGQLHAEGFIERRVGSGSFVAEMTEFAPGRRLSQRDALLRSQAPKLSKRGTAM
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHCCCEE
FGSGGIREQLLPRPFVHGVPETRTFPLPLWERLERQVRKELGAQTLLHCDPQGTEPLRRA
ECCCCCHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHH
IADYVNLERGARAAADRVLVLTSSQQALSLCANMLLDPGDRVFIEDPAYYGARKAFDAAG
HHHHHHHHHCCHHHHCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHCHHHHHHCCC
LECVPIPVDRQGLVVDQITAQPRRAKAVFLTPSHQFPTGATLALDRRLALIEWAARHQTW
CEEEECCCCCCCCEEHHHCCCCCCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHCCEE
IIEDDYDSEFHYAGKPTACVQGLDPHDRTVYIGTFTKSLFPGLRIGYVVLPPQLVKPMTV
EEECCCCCCCEECCCCHHHHCCCCCCCCEEEEEECHHHHCCCCEEEEEEECHHHHHHHHH
ARTLLDGHSASMAQLTLARFMEGGHFGAHVRTMRGVYAQRLDVLVRLVRKYLSGLVEPRV
HHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVGGLQLPCVLTCDLAERTAVDAAQRVGIELLGLSGLQHARHGEAGFLMGFAAYTPLEIE
CCCCCCCCEEEEECCHHHHHHHHHHHCCEEEECCCCHHHHCCCCCCEEEHHHHCCCEEHH
GAVKKLAKALRAAAKS
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]