Click here to switch to the map view.

The map label for this gene is bglA [H]

Identifier: 192290329

GI number: 192290329

Start: 2087851

End: 2089227

Strand: Reverse

Name: bglA [H]

Synonym: Rpal_1936

Alternate gene names: 192290329

Gene position: 2089227-2087851 (Counterclockwise)

Preceding gene: 192290330

Following gene: 192290327

Centisome position: 36.37

GC content: 63.62

Gene sequence:

>1377_bases
ATGGCCTCATCGCTCATCCCTCCCGCCTCTGAGCCCGTGGCCGGTTTGCCGGTGTTGTCGCACATCCGCAAAGACTTCAT
CTGGGGCGTGTCGACCGCGAGCTTCCAGATCGAAGGCGCCGCCAACGAGGACGGCCGCGGCCAGAGCATCTGGGACGTGT
ATTGCCGCTCCGGCTATGTCGCCAACAACGACACCGGCGATGTCGCTTGCGATCACTATCATCGCTACCAGGAAGACGTC
GCGCTGATGAAGACGCTCGGCATTCAGGCGTATCGATTCTCGATCGCCTGGCCGCGGATCTTCCCGCAAGGCACCGGCGC
GATCAACGAGCCCGGCCTCGCCTTCTATGATCGCCTGATTGATGCGCTGGAGGCCGCCGGCATCGAGCCGTGGATCTGCC
TGTATCATTGGGATCTGCCGCAAGCGATGGAAGAGCGCGGCGGCTGGATGAATCGCGATATCGTCGGCTGGTTCGCCGAC
TACGCGCGGGTGATCGGCGAGCGTTACGGCAAGCGCGTGAAGCGGTTTGCCACCTTCAATGAGCCCGGCATCTTCAGCCT
GTTCAGCCGCTCGTTCGGCGCGCGCGACCGCAGCGCCGACGAGAAGCTGCACCGCTGGATTCACCACGTCAATCTGGCGC
ACGGCGCCGCCGTCGACGTGCTGCGCGAGACCGTGGCGGATGCAAAGATCGGATTGGTCACCAACTATCAGCCGGTGTAC
CCGTCGAGCGACAAGCCGGAAGACGTCGCTGAGGCCAAGCTGATCAGCGACTACTGGAATCGCGCTTTCGCCGATCCGCA
ATATCGCGGTGAGTATCCAGGCCTGATCCGCGACGCCGTCAAGCCGTATATCCAGCCCGGCGACATGGAGCGCATCCACC
GGCCGCTCGACTGGTTCGGCCTGAACCATTACAGCCCCGTCTATATCAACTCCGATCCGAACGCGATCGTCGGACTCGGC
TGGGGGCCGAAGCCCGAGGGTATTCCGCGCTCGCCGATCGACTGGACGATCGAGCCGGATGCCTTCCGCGATACGCTGAT
CGAGATCAGCCGCCGCTACGGCAAGCCGGTTTACGTCACCGAGAACGGTTACGGCAGCAATATCGAGAAGCCAGACGCCA
ACGGCGAAGTGGTCGATCCTGGCAGGATCGGCTTCCTGCGCGACTACATCACCGCCCTCGACCAGGCGGTCGCAGCCGGC
GCCGATGTGCGCGGCTACATGGTGTGGTCGCTGCTCGACAATTTCGAGTGGGAGTCCGGCTACAGCGTGCGCTTTGGGCT
GATCTACATCGACTATGCGACGCTGCGCCGGATTCCGAAGGCGTCGTTCAAGTGGTTCGCCGACGTGATCCGTCACGCCC
GCGGCGCGAGCGCCTAA

Upstream 100 bases:

>100_bases
TCAACCGCACGGGCGTCACAACGTCGCTGTTTGATTCAACGCAAGCGGCGCCGTCTGCGCCGCGGCGTATCAAATGACAC
CTGCAATCGGAGATTTCGCC

Downstream 100 bases:

>100_bases
GCAGAGGGGCGCAGTCTACGGCGACGCCAGCTCGCGCGACGGCTCGGCTGGCGTTGCCGGCGTGCGGTCCGGCATCGCAT
CGATCGCGGCCAGCAGGGCC

Product: beta-galactosidase

Products: NA

Alternate protein names: Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MASSLIPPASEPVAGLPVLSHIRKDFIWGVSTASFQIEGAANEDGRGQSIWDVYCRSGYVANNDTGDVACDHYHRYQEDV
ALMKTLGIQAYRFSIAWPRIFPQGTGAINEPGLAFYDRLIDALEAAGIEPWICLYHWDLPQAMEERGGWMNRDIVGWFAD
YARVIGERYGKRVKRFATFNEPGIFSLFSRSFGARDRSADEKLHRWIHHVNLAHGAAVDVLRETVADAKIGLVTNYQPVY
PSSDKPEDVAEAKLISDYWNRAFADPQYRGEYPGLIRDAVKPYIQPGDMERIHRPLDWFGLNHYSPVYINSDPNAIVGLG
WGPKPEGIPRSPIDWTIEPDAFRDTLIEISRRYGKPVYVTENGYGSNIEKPDANGEVVDPGRIGFLRDYITALDQAVAAG
ADVRGYMVWSLLDNFEWESGYSVRFGLIYIDYATLRRIPKASFKWFADVIRHARGASA

Sequences:

>Translated_458_residues
MASSLIPPASEPVAGLPVLSHIRKDFIWGVSTASFQIEGAANEDGRGQSIWDVYCRSGYVANNDTGDVACDHYHRYQEDV
ALMKTLGIQAYRFSIAWPRIFPQGTGAINEPGLAFYDRLIDALEAAGIEPWICLYHWDLPQAMEERGGWMNRDIVGWFAD
YARVIGERYGKRVKRFATFNEPGIFSLFSRSFGARDRSADEKLHRWIHHVNLAHGAAVDVLRETVADAKIGLVTNYQPVY
PSSDKPEDVAEAKLISDYWNRAFADPQYRGEYPGLIRDAVKPYIQPGDMERIHRPLDWFGLNHYSPVYINSDPNAIVGLG
WGPKPEGIPRSPIDWTIEPDAFRDTLIEISRRYGKPVYVTENGYGSNIEKPDANGEVVDPGRIGFLRDYITALDQAVAAG
ADVRGYMVWSLLDNFEWESGYSVRFGLIYIDYATLRRIPKASFKWFADVIRHARGASA
>Mature_457_residues
ASSLIPPASEPVAGLPVLSHIRKDFIWGVSTASFQIEGAANEDGRGQSIWDVYCRSGYVANNDTGDVACDHYHRYQEDVA
LMKTLGIQAYRFSIAWPRIFPQGTGAINEPGLAFYDRLIDALEAAGIEPWICLYHWDLPQAMEERGGWMNRDIVGWFADY
ARVIGERYGKRVKRFATFNEPGIFSLFSRSFGARDRSADEKLHRWIHHVNLAHGAAVDVLRETVADAKIGLVTNYQPVYP
SSDKPEDVAEAKLISDYWNRAFADPQYRGEYPGLIRDAVKPYIQPGDMERIHRPLDWFGLNHYSPVYINSDPNAIVGLGW
GPKPEGIPRSPIDWTIEPDAFRDTLIEISRRYGKPVYVTENGYGSNIEKPDANGEVVDPGRIGFLRDYITALDQAVAAGA
DVRGYMVWSLLDNFEWESGYSVRFGLIYIDYATLRRIPKASFKWFADVIRHARGASA

Specific function: Can Hydrolyze Salicin And Arbutin. [C]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=464, Percent_Identity=36.6379310344828, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI110681710, Length=471, Percent_Identity=34.1825902335456, Blast_Score=242, Evalue=4e-64,
Organism=Homo sapiens, GI13273313, Length=463, Percent_Identity=30.2375809935205, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI28376633, Length=451, Percent_Identity=28.3813747228381, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI24497614, Length=481, Percent_Identity=27.6507276507277, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI190360571, Length=141, Percent_Identity=35.4609929078014, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI2367270, Length=461, Percent_Identity=34.2733188720174, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI2367174, Length=468, Percent_Identity=32.9059829059829, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1789070, Length=469, Percent_Identity=32.409381663113, Blast_Score=210, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17539390, Length=467, Percent_Identity=28.4796573875803, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17552856, Length=482, Percent_Identity=28.0082987551867, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21356577, Length=475, Percent_Identity=31.3684210526316, Blast_Score=223, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 51653; Mature: 51521

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSLIPPASEPVAGLPVLSHIRKDFIWGVSTASFQIEGAANEDGRGQSIWDVYCRSGYV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCCEE
ANNDTGDVACDHYHRYQEDVALMKTLGIQAYRFSIAWPRIFPQGTGAINEPGLAFYDRLI
CCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
DALEAAGIEPWICLYHWDLPQAMEERGGWMNRDIVGWFADYARVIGERYGKRVKRFATFN
HHHHHCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EPGIFSLFSRSFGARDRSADEKLHRWIHHVNLAHGAAVDVLRETVADAKIGLVTNYQPVY
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
PSSDKPEDVAEAKLISDYWNRAFADPQYRGEYPGLIRDAVKPYIQPGDMERIHRPLDWFG
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHCCHHHHC
LNHYSPVYINSDPNAIVGLGWGPKPEGIPRSPIDWTIEPDAFRDTLIEISRRYGKPVYVT
CCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCEEEE
ENGYGSNIEKPDANGEVVDPGRIGFLRDYITALDQAVAAGADVRGYMVWSLLDNFEWESG
CCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
YSVRFGLIYIDYATLRRIPKASFKWFADVIRHARGASA
CEEEEEEEEEEHHHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASSLIPPASEPVAGLPVLSHIRKDFIWGVSTASFQIEGAANEDGRGQSIWDVYCRSGYV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCCEE
ANNDTGDVACDHYHRYQEDVALMKTLGIQAYRFSIAWPRIFPQGTGAINEPGLAFYDRLI
CCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
DALEAAGIEPWICLYHWDLPQAMEERGGWMNRDIVGWFADYARVIGERYGKRVKRFATFN
HHHHHCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EPGIFSLFSRSFGARDRSADEKLHRWIHHVNLAHGAAVDVLRETVADAKIGLVTNYQPVY
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
PSSDKPEDVAEAKLISDYWNRAFADPQYRGEYPGLIRDAVKPYIQPGDMERIHRPLDWFG
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHCCHHHHC
LNHYSPVYINSDPNAIVGLGWGPKPEGIPRSPIDWTIEPDAFRDTLIEISRRYGKPVYVT
CCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCEEEE
ENGYGSNIEKPDANGEVVDPGRIGFLRDYITALDQAVAAGADVRGYMVWSLLDNFEWESG
CCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
YSVRFGLIYIDYATLRRIPKASFKWFADVIRHARGASA
CEEEEEEEEEEHHHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1909624 [H]