BacMap

Definition	Rhodopseudomonas palustris TIE-1 chromosome, complete genome.
Accession	NC_011004
Length	5,744,041

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The map label for this gene is xecD [H]

Identifier: 192289896

GI number: 192289896

Start: 1571029

End: 1571880

Strand: Reverse

Name: xecD [H]

Synonym: Rpal_1488

Alternate gene names: 192289896

Gene position: 1571880-1571029 (Counterclockwise)

Preceding gene: 192289897

Following gene: 192289894

Centisome position: 27.37

GC content: 68.66

Gene sequence:

>852_bases
ATGCCGCATCCCGCCATTGCCAAGGATCAGGTCGCCGTGGTCACCGGCGGCGCATCGGGGATCGGCTTTGCGGCCGCCAA
GCGGTTTCTGCAGGCCGGCATGAAGGTGGCGATCGCGGATCTGAACGCCGATCATCTCGCCCGCGCCGCGGAGCTGCTGG
CGCATGTCGCCAGCAGCGGAGCCGACGACGTGCTGGCGAAGGAAACTGACGTCGCCAAACCCGACCAGCTCGAGGCGCTG
CGCGCCGCCGTCACCGCGCGGTTCGGCGACGTCGACGTGGTGATGAACAATGCCGGCATCGAGCCGCCGAGCACCGCGCT
CGGCCCGCGCGAGGCCTATGAGCGCATCCTCAGCGTCAATCTGTGGGGGGTGATCCACGGCTCGCAGATCTTCGCGCCGG
ACATGATCGCGCGCGGCCGGCCGGGGCTGATCATCAACACCGGCTCCAAGCAGGGCATTACCACGCCGCCGGGCAATCCG
GCCTACAATGTCTCCAAGGCCGGTGTGAAAGCCTATACCGAAGCGTTGGCGCATGAGCTGCGCACCACCGAGGGCTGCGC
GGTGACGGCGCATCTGCTCATCCCCGGCTTCGTCTTCACCGCGCTGACCGCGCGCGGGCGCAGCGAGAAGCCGGCCGGCG
CCTGGACCGCCGAGCAGACCGTGGACTTCATGCTGGCGCGGCTTGAGGACAGCGACTTCTACATCCTGTGCCCGGACAAT
GACGTGCCCCGAAGCCTCGACGAACGCCGCATCGCCTGGGCCGCCGGCGACATCATCGACAACCGCCCCGCGCTGTCGCG
CTGGCACCCGGCCTGGGTCGACCGCTTCAGGGCGTTCGTCGAAGGGAAGTAA

Upstream 100 bases:

>100_bases
CGCTCGCAATGACGATCAAAGTCCGCACGTCCCCTCGGCTTGCGTCCTCCGCCGCTGCGCTTATCTCCCGGGCATCGCCA
TCCGCCTCGAGGAGACCGCC

Downstream 100 bases:

>100_bases
CAAGCCACGGCGCCAGCGTCTTCGTGAGAGCCTGACCGGAAATGCGGGCAGCTAATTGAAAGGCTTTGATAAGCCGTTCA
ATTGACGATTAGTTTCGTCA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: R-HPCDH; Aliphatic epoxide carboxylation component III [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MPHPAIAKDQVAVVTGGASGIGFAAAKRFLQAGMKVAIADLNADHLARAAELLAHVASSGADDVLAKETDVAKPDQLEAL
RAAVTARFGDVDVVMNNAGIEPPSTALGPREAYERILSVNLWGVIHGSQIFAPDMIARGRPGLIINTGSKQGITTPPGNP
AYNVSKAGVKAYTEALAHELRTTEGCAVTAHLLIPGFVFTALTARGRSEKPAGAWTAEQTVDFMLARLEDSDFYILCPDN
DVPRSLDERRIAWAAGDIIDNRPALSRWHPAWVDRFRAFVEGK

Sequences:

>Translated_283_residues
MPHPAIAKDQVAVVTGGASGIGFAAAKRFLQAGMKVAIADLNADHLARAAELLAHVASSGADDVLAKETDVAKPDQLEAL
RAAVTARFGDVDVVMNNAGIEPPSTALGPREAYERILSVNLWGVIHGSQIFAPDMIARGRPGLIINTGSKQGITTPPGNP
AYNVSKAGVKAYTEALAHELRTTEGCAVTAHLLIPGFVFTALTARGRSEKPAGAWTAEQTVDFMLARLEDSDFYILCPDN
DVPRSLDERRIAWAAGDIIDNRPALSRWHPAWVDRFRAFVEGK
>Mature_282_residues
PHPAIAKDQVAVVTGGASGIGFAAAKRFLQAGMKVAIADLNADHLARAAELLAHVASSGADDVLAKETDVAKPDQLEALR
AAVTARFGDVDVVMNNAGIEPPSTALGPREAYERILSVNLWGVIHGSQIFAPDMIARGRPGLIINTGSKQGITTPPGNPA
YNVSKAGVKAYTEALAHELRTTEGCAVTAHLLIPGFVFTALTARGRSEKPAGAWTAEQTVDFMLARLEDSDFYILCPDND
VPRSLDERRIAWAAGDIIDNRPALSRWHPAWVDRFRAFVEGK

Specific function: Catalyzes the oxidation of 2-(R)-hydroxyalkyl thioesters of CoM to 2-oxoalkyl thioesters of CoM. The enzyme highly specific for the R enantiomers [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=218, Percent_Identity=32.5688073394495, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI20149619, Length=205, Percent_Identity=29.2682926829268, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=26.984126984127, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI83715985, Length=186, Percent_Identity=31.7204301075269, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4758504, Length=186, Percent_Identity=31.7204301075269, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI109715829, Length=235, Percent_Identity=28.0851063829787, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI25282469, Length=223, Percent_Identity=26.457399103139, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254992, Length=202, Percent_Identity=28.7128712871287, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI32483357, Length=197, Percent_Identity=27.4111675126904, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789208, Length=217, Percent_Identity=29.4930875576037, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787335, Length=195, Percent_Identity=29.7435897435897, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=28.6458333333333, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787905, Length=130, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789057, Length=192, Percent_Identity=30.2083333333333, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790717, Length=210, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082160, Length=203, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=197, Percent_Identity=31.9796954314721, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=201, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=219, Percent_Identity=26.9406392694064, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=226, Percent_Identity=29.2035398230088, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=223, Percent_Identity=29.1479820627803, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=230, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=216, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=215, Percent_Identity=29.3023255813954, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=184, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=229, Percent_Identity=30.1310043668122, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=213, Percent_Identity=24.4131455399061, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=179, Percent_Identity=31.8435754189944, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=203, Percent_Identity=32.0197044334975, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323882, Length=215, Percent_Identity=26.9767441860465, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=28.9772727272727, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=202, Percent_Identity=25.7425742574257, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24644339, Length=198, Percent_Identity=32.3232323232323, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21357041, Length=206, Percent_Identity=32.0388349514563, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21355631, Length=176, Percent_Identity=31.8181818181818, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28571526, Length=200, Percent_Identity=32, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221331218, Length=171, Percent_Identity=36.2573099415205, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24665243, Length=171, Percent_Identity=36.2573099415205, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221331216, Length=172, Percent_Identity=36.6279069767442, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24665247, Length=172, Percent_Identity=36.6279069767442, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24665264, Length=195, Percent_Identity=31.7948717948718, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=26.7676767676768, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=31.6062176165803, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=26.5625, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737361, Length=209, Percent_Identity=28.7081339712919, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584752, Length=208, Percent_Identity=29.8076923076923, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI116007232, Length=181, Percent_Identity=31.4917127071823, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI116007234, Length=181, Percent_Identity=31.4917127071823, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.268 [H]

Molecular weight: Translated: 30183; Mature: 30051

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHPAIAKDQVAVVTGGASGIGFAAAKRFLQAGMKVAIADLNADHLARAAELLAHVASSG
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCC
ADDVLAKETDVAKPDQLEALRAAVTARFGDVDVVMNNAGIEPPSTALGPREAYERILSVN
CCHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
LWGVIHGSQIFAPDMIARGRPGLIINTGSKQGITTPPGNPAYNVSKAGVKAYTEALAHEL
EEEEEECCEECCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RTTEGCAVTAHLLIPGFVFTALTARGRSEKPAGAWTAEQTVDFMLARLEDSDFYILCPDN
HCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCC
DVPRSLDERRIAWAAGDIIDNRPALSRWHPAWVDRFRAFVEGK
CCCCCHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PHPAIAKDQVAVVTGGASGIGFAAAKRFLQAGMKVAIADLNADHLARAAELLAHVASSG
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCC
ADDVLAKETDVAKPDQLEALRAAVTARFGDVDVVMNNAGIEPPSTALGPREAYERILSVN
CCHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
LWGVIHGSQIFAPDMIARGRPGLIINTGSKQGITTPPGNPAYNVSKAGVKAYTEALAHEL
EEEEEECCEECCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RTTEGCAVTAHLLIPGFVFTALTARGRSEKPAGAWTAEQTVDFMLARLEDSDFYILCPDN
HCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCC
DVPRSLDERRIAWAAGDIIDNRPALSRWHPAWVDRFRAFVEGK
CCCCCHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704278; 9405410; 12524213 [H]