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The map label for this gene is fur [H]

Identifier: 192288885

GI number: 192288885

Start: 489614

End: 490045

Strand: Reverse

Name: fur [H]

Synonym: Rpal_0454

Alternate gene names: 192288885

Gene position: 490045-489614 (Counterclockwise)

Preceding gene: 192288886

Following gene: 192288884

Centisome position: 8.53

GC content: 60.19

Gene sequence:

>432_bases
ATGTCCGAACCCAAGGCAACTGAAATCGAAGCCCGCTGTGCCGCCACCGGCATGCGCATGACGGAGCAGCGCCGCGTGAT
CGCACGAGTTCTGGCGGAGTCGGAAGACCATCCCGACGTCGAAGAACTGTACACCCGCTGCGTTGCGATCGACGACAAGA
TCTCGATCTCGACGGTGTACCGTACCGTCAAGCTGTTCGAAGATGCCGGCATCATCGAACGTCACGACTTCCGTGAAGGC
CGCGCCCGCTACGAGCAGATGCGTGACAGCCATCATGACCACCTGATCAACCTGCGCGACGGCACGGTGATCGAGTTCAC
CAACGAAGAGATCGAGAAGCTGCAGGCCGAGATCGCCCGCCGCCTCGGTTACAAGCTGGTCGATCATCGGCTCGAGCTGT
ATTGCGTGCCGCTCGAAGACGATAAGTCCTGA

Upstream 100 bases:

>100_bases
AATTGAACGCATTGATAATGCGTCGCGACTTGTCCTGATCGCCCTGCAGTGGCAGAACAATGACCAAGATAACCATTCAC
CCGCAACCACGTTGACGCCG

Downstream 100 bases:

>100_bases
GCTGCAGCGCGAACTGACGCATCTGCCGATCCGCCGCGAGCTCACCGGCTCGCGGCGTATTAGTTTAAACTGCAGCCGGC
CGCAGATGTGACTCCCGAAC

Product: Fur family ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MSEPKATEIEARCAATGMRMTEQRRVIARVLAESEDHPDVEELYTRCVAIDDKISISTVYRTVKLFEDAGIIERHDFREG
RARYEQMRDSHHDHLINLRDGTVIEFTNEEIEKLQAEIARRLGYKLVDHRLELYCVPLEDDKS

Sequences:

>Translated_143_residues
MSEPKATEIEARCAATGMRMTEQRRVIARVLAESEDHPDVEELYTRCVAIDDKISISTVYRTVKLFEDAGIIERHDFREG
RARYEQMRDSHHDHLINLRDGTVIEFTNEEIEKLQAEIARRLGYKLVDHRLELYCVPLEDDKS
>Mature_142_residues
SEPKATEIEARCAATGMRMTEQRRVIARVLAESEDHPDVEELYTRCVAIDDKISISTVYRTVKLFEDAGIIERHDFREGR
ARYEQMRDSHHDHLINLRDGTVIEFTNEEIEKLQAEIARRLGYKLVDHRLELYCVPLEDDKS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=127, Percent_Identity=41.7322834645669, Blast_Score=100, Evalue=5e-23,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16719; Mature: 16588

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPKATEIEARCAATGMRMTEQRRVIARVLAESEDHPDVEELYTRCVAIDDKISISTVY
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHH
RTVKLFEDAGIIERHDFREGRARYEQMRDSHHDHLINLRDGTVIEFTNEEIEKLQAEIAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECHHHHHHHHHHHHH
RLGYKLVDHRLELYCVPLEDDKS
HHHHHHHCCCEEEEEEECCCCCC
>Mature Secondary Structure 
SEPKATEIEARCAATGMRMTEQRRVIARVLAESEDHPDVEELYTRCVAIDDKISISTVY
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHH
RTVKLFEDAGIIERHDFREGRARYEQMRDSHHDHLINLRDGTVIEFTNEEIEKLQAEIAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECHHHHHHHHHHHHH
RLGYKLVDHRLELYCVPLEDDKS
HHHHHHHCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9835040 [H]