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The map label for this gene is yieH [H]

Identifier: 192288884

GI number: 192288884

Start: 488867

End: 489526

Strand: Reverse

Name: yieH [H]

Synonym: Rpal_0453

Alternate gene names: 192288884

Gene position: 489526-488867 (Counterclockwise)

Preceding gene: 192288885

Following gene: 192288883

Centisome position: 8.52

GC content: 64.55

Gene sequence:

>660_bases
GTGACTCCCGAACTTGTTATTTTCGATTGTGACGGTGTCCTGGTCGACAGTGAGCTGATCTCCTGTCGGATTCACGCCGA
GACGCTGACCCGCTACGGCTATCCGATCACGCCGGACCAAGTCGCGGCGCGCTTCCTCGGCCGTTCGGGCCGCGAAGCCC
GGCGCGAGATCGAAGCCGAGATTGGCCGGCGCTTCGCCGACGACATCGAAGCAAACCTGCTCGACGCGCTGCTGCGCGCT
TTCGCCGAAACGTTGCAGCCGATCCCATTCGTCACCGACGCTCTCGACACGCTTGGACGACCGTTCTGCGTCGCCTCGAG
CGGCACGCTCGATCGCATCGGGGTGGCGCTGACCCATGCCGGCCTGCATGCCCGGTTCGCCCCGCATCTGTTTTCGGCCC
AGCAGGTCGCGCACGGCAAACCGGCGCCCGACCTGTTCCTGTTCGCGGCGGCCCAGATGGGCGCAGCCCCGGAGCGCTGC
GTGGTGATCGAAGACAGCGTGCCCGGGGTGCTGGGTGCGAAAGCGGCCGGCATGACCGTGCTCGGTTTTCACGGCGGCAG
TCATTGCACCGATGCTACTGCCGCCGCACTGGCCGCTGCCGGGGCCGACCGCTGTTTTGACGACATGAGACAATTAACTG
AAATAATTGAAGAAATTTAG

Upstream 100 bases:

>100_bases
CGATAAGTCCTGAGCTGCAGCGCGAACTGACGCATCTGCCGATCCGCCGCGAGCTCACCGGCTCGCGGCGTATTAGTTTA
AACTGCAGCCGGCCGCAGAT

Downstream 100 bases:

>100_bases
ACGTCCGGCGGAGCGGACGCGGCAAATCGCCGGTCGCGGCTGGATTTCGTCGGGTTTCGCCTATAAGTGACGGTAACGCG
CTGGAACACGCGCGTTTTTT

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTPELVIFDCDGVLVDSELISCRIHAETLTRYGYPITPDQVAARFLGRSGREARREIEAEIGRRFADDIEANLLDALLRA
FAETLQPIPFVTDALDTLGRPFCVASSGTLDRIGVALTHAGLHARFAPHLFSAQQVAHGKPAPDLFLFAAAQMGAAPERC
VVIEDSVPGVLGAKAAGMTVLGFHGGSHCTDATAAALAAAGADRCFDDMRQLTEIIEEI

Sequences:

>Translated_219_residues
MTPELVIFDCDGVLVDSELISCRIHAETLTRYGYPITPDQVAARFLGRSGREARREIEAEIGRRFADDIEANLLDALLRA
FAETLQPIPFVTDALDTLGRPFCVASSGTLDRIGVALTHAGLHARFAPHLFSAQQVAHGKPAPDLFLFAAAQMGAAPERC
VVIEDSVPGVLGAKAAGMTVLGFHGGSHCTDATAAALAAAGADRCFDDMRQLTEIIEEI
>Mature_218_residues
TPELVIFDCDGVLVDSELISCRIHAETLTRYGYPITPDQVAARFLGRSGREARREIEAEIGRRFADDIEANLLDALLRAF
AETLQPIPFVTDALDTLGRPFCVASSGTLDRIGVALTHAGLHARFAPHLFSAQQVAHGKPAPDLFLFAAAQMGAAPERCV
VIEDSVPGVLGAKAAGMTVLGFHGGSHCTDATAAALAAAGADRCFDDMRQLTEIIEEI

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=186, Percent_Identity=31.1827956989247, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789046, Length=174, Percent_Identity=31.6091954022989, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082080, Length=183, Percent_Identity=32.2404371584699, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116008157, Length=186, Percent_Identity=30.6451612903226, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 23345; Mature: 23214

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPELVIFDCDGVLVDSELISCRIHAETLTRYGYPITPDQVAARFLGRSGREARREIEAE
CCCCEEEEECCCEEECHHHHHEEHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
IGRRFADDIEANLLDALLRAFAETLQPIPFVTDALDTLGRPFCVASSGTLDRIGVALTHA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHC
GLHARFAPHLFSAQQVAHGKPAPDLFLFAAAQMGAAPERCVVIEDSVPGVLGAKAAGMTV
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCEEE
LGFHGGSHCTDATAAALAAAGADRCFDDMRQLTEIIEEI
EEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TPELVIFDCDGVLVDSELISCRIHAETLTRYGYPITPDQVAARFLGRSGREARREIEAE
CCCEEEEECCCEEECHHHHHEEHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
IGRRFADDIEANLLDALLRAFAETLQPIPFVTDALDTLGRPFCVASSGTLDRIGVALTHA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHC
GLHARFAPHLFSAQQVAHGKPAPDLFLFAAAQMGAAPERCVVIEDSVPGVLGAKAAGMTV
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCEEE
LGFHGGSHCTDATAAALAAAGADRCFDDMRQLTEIIEEI
EEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]