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The map label for this gene is thuBc [H]

Identifier: 190894733

GI number: 190894733

Start: 422964

End: 424001

Strand: Reverse

Name: thuBc [H]

Synonym: RHECIAT_PC0000398

Alternate gene names: 190894733

Gene position: 424001-422964 (Counterclockwise)

Preceding gene: 190894734

Following gene: 190894727

Centisome position: 38.84

GC content: 60.79

Gene sequence:

>1038_bases
ATGCGCTTGATCATTCTCGGTACCGGAGGATGGGCAAATACCCATGCCATGCATTTTTCGGAGATCGCCGACGTCAAAAT
TGTTGCTGCCGTCGATACGGACGAGGTTCGGCTGCGGGCCTTCGCGCTCAGGCATACTATCCCGCTGACGTTCACGTCGC
TTGATGACGCCCTTGCCTGGGGAGAGTTTGACGCCGTCACCAATGTCACGCCGGATCGCGCGCACTATGCCACGACGATG
AAGTTACTTGCCGCGGGCAAGCATGTCCTCTGCGAGAAGCCGCTGGCGGTCAACTACCGCGAAGCCAAGGAAATGGCCGA
TGCGGCCGCGGCATCCGGCAAGGTCACGATGGTCAACCTGACCTATCGGAACGTGGCCCCGCTGCAAGCCGCGCGCAAGA
TGGTGCTGGACGGGCGCCTCGGCGCGATCCGCCACTTCGAAGCGTCCTATCTGCAGAGCTGGCTGGTTTCGAAGGCCTGG
GGCGACTGGACCAAGGAATCGCAATGGCTCTGGCGACTGTCGACGAAGCACGGCTCCAATGGCGTGCTGGGCGATGTCGG
TATCCACATTCTCGATTTCGCGGTATTTGCCGCGGGAAGCGATGTCAAGGCGGCGGCATCGCATCTCAAGGTGTTCGACA
AGAGCCCCGGAAACCGAATCGGCGAATATGAGCTCGACGCAAACGACAGTTTCCTGATGATGGCCGAACTCGAAAACGGT
GCAGCCGGCGTCATCCATGCGACGCGCTGGGCGACCGGCCATCTGAACGAACTGCGCCTGCGCCTGCATGGAGACAAGGG
TGCCCTGGAGGTGGTGCACACGCCTGAAGGCTCCACCCTCAGGACCTGTGAAGGCGCCGATGCCGACAAGGCGATCTGGC
GCACGATCGAGGTCGAACCGGTCATGACGAATTTCCAGCGATTTGCAAAGGCCGTGCAAAAGGGGCAGCCGGATGAGCCA
GGTTTTGGCCACGCCGCCAAGCTGCAATTTGTTCTCGACCACGCCGTAAAGACCGCTGGCGCTTTGACTGAGCTTTAG

Upstream 100 bases:

>100_bases
ATAGATGAGATGCCGTGGGCAGGGCCCGTTTGGCCCCGCAAGACGCCGCGATGATCTCGCGGCCGCTCACGCTTTGATGG
ATAACGATGAGGATAAAAGA

Downstream 100 bases:

>100_bases
ACGAAAAAGTTCAGACGGGTTCCTCGGCGGTCTTGCGGGAGGTCACCGCGCGGCGCGGCCAACCTCGTCAAACTCGCCTG
CTCAGTTCATCTTCGCTCAC

Product: myo-inositol 2-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MRLIILGTGGWANTHAMHFSEIADVKIVAAVDTDEVRLRAFALRHTIPLTFTSLDDALAWGEFDAVTNVTPDRAHYATTM
KLLAAGKHVLCEKPLAVNYREAKEMADAAAASGKVTMVNLTYRNVAPLQAARKMVLDGRLGAIRHFEASYLQSWLVSKAW
GDWTKESQWLWRLSTKHGSNGVLGDVGIHILDFAVFAAGSDVKAAASHLKVFDKSPGNRIGEYELDANDSFLMMAELENG
AAGVIHATRWATGHLNELRLRLHGDKGALEVVHTPEGSTLRTCEGADADKAIWRTIEVEPVMTNFQRFAKAVQKGQPDEP
GFGHAAKLQFVLDHAVKTAGALTEL

Sequences:

>Translated_345_residues
MRLIILGTGGWANTHAMHFSEIADVKIVAAVDTDEVRLRAFALRHTIPLTFTSLDDALAWGEFDAVTNVTPDRAHYATTM
KLLAAGKHVLCEKPLAVNYREAKEMADAAAASGKVTMVNLTYRNVAPLQAARKMVLDGRLGAIRHFEASYLQSWLVSKAW
GDWTKESQWLWRLSTKHGSNGVLGDVGIHILDFAVFAAGSDVKAAASHLKVFDKSPGNRIGEYELDANDSFLMMAELENG
AAGVIHATRWATGHLNELRLRLHGDKGALEVVHTPEGSTLRTCEGADADKAIWRTIEVEPVMTNFQRFAKAVQKGQPDEP
GFGHAAKLQFVLDHAVKTAGALTEL
>Mature_345_residues
MRLIILGTGGWANTHAMHFSEIADVKIVAAVDTDEVRLRAFALRHTIPLTFTSLDDALAWGEFDAVTNVTPDRAHYATTM
KLLAAGKHVLCEKPLAVNYREAKEMADAAAASGKVTMVNLTYRNVAPLQAARKMVLDGRLGAIRHFEASYLQSWLVSKAW
GDWTKESQWLWRLSTKHGSNGVLGDVGIHILDFAVFAAGSDVKAAASHLKVFDKSPGNRIGEYELDANDSFLMMAELENG
AAGVIHATRWATGHLNELRLRLHGDKGALEVVHTPEGSTLRTCEGADADKAIWRTIEVEPVMTNFQRFAKAVQKGQPDEP
GFGHAAKLQFVLDHAVKTAGALTEL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=248, Percent_Identity=31.0483870967742, Blast_Score=95, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24581117, Length=126, Percent_Identity=31.7460317460317, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37674; Mature: 37674

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIILGTGGWANTHAMHFSEIADVKIVAAVDTDEVRLRAFALRHTIPLTFTSLDDALAW
CEEEEEECCCCCCCCHHHHHHHCCEEEEEEECCCHHHHHEEHHHHCCCEEEECCHHHHHC
GEFDAVTNVTPDRAHYATTMKLLAAGKHVLCEKPLAVNYREAKEMADAAAASGKVTMVNL
CCCCHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEE
TYRNVAPLQAARKMVLDGRLGAIRHFEASYLQSWLVSKAWGDWTKESQWLWRLSTKHGSN
EECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
GVLGDVGIHILDFAVFAAGSDVKAAASHLKVFDKSPGNRIGEYELDANDSFLMMAELENG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCC
AAGVIHATRWATGHLNELRLRLHGDKGALEVVHTPEGSTLRTCEGADADKAIWRTIEVEP
CEEEEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCEEEECCCCCCCCHHEEEEEECH
VMTNFQRFAKAVQKGQPDEPGFGHAAKLQFVLDHAVKTAGALTEL
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLIILGTGGWANTHAMHFSEIADVKIVAAVDTDEVRLRAFALRHTIPLTFTSLDDALAW
CEEEEEECCCCCCCCHHHHHHHCCEEEEEEECCCHHHHHEEHHHHCCCEEEECCHHHHHC
GEFDAVTNVTPDRAHYATTMKLLAAGKHVLCEKPLAVNYREAKEMADAAAASGKVTMVNL
CCCCHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEE
TYRNVAPLQAARKMVLDGRLGAIRHFEASYLQSWLVSKAWGDWTKESQWLWRLSTKHGSN
EECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
GVLGDVGIHILDFAVFAAGSDVKAAASHLKVFDKSPGNRIGEYELDANDSFLMMAELENG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCC
AAGVIHATRWATGHLNELRLRLHGDKGALEVVHTPEGSTLRTCEGADADKAIWRTIEVEP
CEEEEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCEEEECCCCCCCCHHEEEEEECH
VMTNFQRFAKAVQKGQPDEPGFGHAAKLQFVLDHAVKTAGALTEL
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]