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The map label for this gene is eutB [C]

Identifier: 190894711

GI number: 190894711

Start: 400077

End: 401078

Strand: Reverse

Name: eutB [C]

Synonym: RHECIAT_PC0000376

Alternate gene names: 190894711

Gene position: 401078-400077 (Counterclockwise)

Preceding gene: 190894712

Following gene: 190894710

Centisome position: 36.74

GC content: 67.96

Gene sequence:

>1002_bases
ATGGTGGCCACCTTGCCCGTTTCACTGCAGGACATTCGCGCGGCCGCGAGGCGGATCGCCGGCCGGGTTCTCGCAACGCC
GATGGTGCAATCCGCAGCGCTTGGCGACATTGCCGGCGTTCCCGTTTGGCTGAAGCTCGAACACCATCAGACGACCGGCA
GTTTCAAGCTGCGCGGGGCGACCAACGCAGTGCTCTCGCTGTCGCCGGCAGAACGTGCGCGCGGCGTTGTCGCCGCCTCG
ACAGGAAATCACGGCCGGGCGCTTGCCTATGCGGCCAAGGCTGAAGGCACCGTCGCGACGATCTGCATGTCGCGGCTGGT
GCCGGAGAACAAGGTTGCGGAAATCCGCCGCCTCGGCGCCGAGATCCGCATCGTCGGGCGATCGCAGGACGAGGCGCAGC
AGGAGGTGGACCGGCTGGTGCGCGAGGACGGGCTGGTGATGGTCCCGCCCTTCGACCATCCCGATGTCGTCGCCGGGCAG
GGGACGCTGGGGCTCGAGATCATCGACGCCTTGCCGGAAGCGGCGATGGTGCTGGTGCCTCTGTCGGGCGGCGGCCTTGC
GGCGGGCGTCGCAGCCGCGGTCAAGGGTGTCAATCCCAACACGAAGGTGATCGGCCTGACGATGGAACGGGGGGCCGCGA
TGAAGGCAAGCCTCGATGCCGGCCGGCCGGTGCAGGTCGAGGAAGTGAGCAGCCTTGCCGACTCGCTCGGCGGCGGCATC
GGCCTCGACAACCGCGTGACCTTTGCCATGTGCCGCGACCTTCTCGATGACGTGGTCCTGCTGACGGAGGCGGAGATCGC
CGCCGGCATGCGCCATGCCTGTGCCTGTGAGGGCGAGATTATCGAGGGGGCGGGCGCAGTCGGCATCGCAGCCTTGCTGG
CGGGGAAAATCAGGCCGGCCGGCCCCATCGTTGCGGTCCTTTCCGGCTGCAATGTCGACATGGAACAGCATCGTCGGGTG
ACGGACGGCGAGACTGCAATCTGCGCGGAGGATGGCCCATGA

Upstream 100 bases:

>100_bases
CTCGCAACCGCCTGGGCCTGTCTGAGGCTTTGCGGCGATGATCGGCCGCAGCCCGAACTCGGTCAGCTGATGGCCAGGCC
CTATCGGGAAGGCTGAGATC

Downstream 100 bases:

>100_bases
GCCGGATGATCATTCTGACGGAGGCGGAATTGCGAGAGATTGTCGTGCTCGACCGCGATGCGGTCGCCTGCGTCGAAGAG
GCTTTCGCAGCGCTCGCGAC

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MVATLPVSLQDIRAAARRIAGRVLATPMVQSAALGDIAGVPVWLKLEHHQTTGSFKLRGATNAVLSLSPAERARGVVAAS
TGNHGRALAYAAKAEGTVATICMSRLVPENKVAEIRRLGAEIRIVGRSQDEAQQEVDRLVREDGLVMVPPFDHPDVVAGQ
GTLGLEIIDALPEAAMVLVPLSGGGLAAGVAAAVKGVNPNTKVIGLTMERGAAMKASLDAGRPVQVEEVSSLADSLGGGI
GLDNRVTFAMCRDLLDDVVLLTEAEIAAGMRHACACEGEIIEGAGAVGIAALLAGKIRPAGPIVAVLSGCNVDMEQHRRV
TDGETAICAEDGP

Sequences:

>Translated_333_residues
MVATLPVSLQDIRAAARRIAGRVLATPMVQSAALGDIAGVPVWLKLEHHQTTGSFKLRGATNAVLSLSPAERARGVVAAS
TGNHGRALAYAAKAEGTVATICMSRLVPENKVAEIRRLGAEIRIVGRSQDEAQQEVDRLVREDGLVMVPPFDHPDVVAGQ
GTLGLEIIDALPEAAMVLVPLSGGGLAAGVAAAVKGVNPNTKVIGLTMERGAAMKASLDAGRPVQVEEVSSLADSLGGGI
GLDNRVTFAMCRDLLDDVVLLTEAEIAAGMRHACACEGEIIEGAGAVGIAALLAGKIRPAGPIVAVLSGCNVDMEQHRRV
TDGETAICAEDGP
>Mature_333_residues
MVATLPVSLQDIRAAARRIAGRVLATPMVQSAALGDIAGVPVWLKLEHHQTTGSFKLRGATNAVLSLSPAERARGVVAAS
TGNHGRALAYAAKAEGTVATICMSRLVPENKVAEIRRLGAEIRIVGRSQDEAQQEVDRLVREDGLVMVPPFDHPDVVAGQ
GTLGLEIIDALPEAAMVLVPLSGGGLAAGVAAAVKGVNPNTKVIGLTMERGAAMKASLDAGRPVQVEEVSSLADSLGGGI
GLDNRVTFAMCRDLLDDVVLLTEAEIAAGMRHACACEGEIIEGAGAVGIAALLAGKIRPAGPIVAVLSGCNVDMEQHRRV
TDGETAICAEDGP

Specific function: Acts On Both Serine And Threonine, And Properly Considered As A Hydroxy Amino Acid Deaminase. [C]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=323, Percent_Identity=35.6037151702786, Blast_Score=174, Evalue=8e-44,
Organism=Homo sapiens, GI19923959, Length=275, Percent_Identity=32, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI33469958, Length=314, Percent_Identity=27.3885350318471, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1789505, Length=320, Percent_Identity=37.1875, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1790207, Length=301, Percent_Identity=35.2159468438538, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71991565, Length=313, Percent_Identity=35.7827476038339, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17537387, Length=315, Percent_Identity=36.1904761904762, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17508781, Length=321, Percent_Identity=28.0373831775701, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322631, Length=324, Percent_Identity=35.1851851851852, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6320930, Length=307, Percent_Identity=34.5276872964169, Blast_Score=154, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6319788, Length=263, Percent_Identity=26.615969581749, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355833, Length=265, Percent_Identity=37.3584905660377, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24645328, Length=169, Percent_Identity=36.094674556213, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014333
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 34227; Mature: 34227

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVATLPVSLQDIRAAARRIAGRVLATPMVQSAALGDIAGVPVWLKLEHHQTTGSFKLRGA
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEECCC
TNAVLSLSPAERARGVVAASTGNHGRALAYAAKAEGTVATICMSRLVPENKVAEIRRLGA
CCEEEEECHHHHHCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCC
EIRIVGRSQDEAQQEVDRLVREDGLVMVPPFDHPDVVAGQGTLGLEIIDALPEAAMVLVP
EEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCCCCEECCCCCCHHHHHHCCCCEEEEEE
LSGGGLAAGVAAAVKGVNPNTKVIGLTMERGAAMKASLDAGRPVQVEEVSSLADSLGGGI
ECCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHCCCC
GLDNRVTFAMCRDLLDDVVLLTEAEIAAGMRHACACEGEIIEGAGAVGIAALLAGKIRPA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCHHHHHHHHHCCCCCC
GPIVAVLSGCNVDMEQHRRVTDGETAICAEDGP
CCEEEEEECCCCCHHHCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MVATLPVSLQDIRAAARRIAGRVLATPMVQSAALGDIAGVPVWLKLEHHQTTGSFKLRGA
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEECCC
TNAVLSLSPAERARGVVAASTGNHGRALAYAAKAEGTVATICMSRLVPENKVAEIRRLGA
CCEEEEECHHHHHCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCC
EIRIVGRSQDEAQQEVDRLVREDGLVMVPPFDHPDVVAGQGTLGLEIIDALPEAAMVLVP
EEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCCCCEECCCCCCHHHHHHCCCCEEEEEE
LSGGGLAAGVAAAVKGVNPNTKVIGLTMERGAAMKASLDAGRPVQVEEVSSLADSLGGGI
ECCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHCCCC
GLDNRVTFAMCRDLLDDVVLLTEAEIAAGMRHACACEGEIIEGAGAVGIAALLAGKIRPA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCHHHHHHHHHCCCCCC
GPIVAVLSGCNVDMEQHRRVTDGETAICAEDGP
CCEEEEEECCCCCHHHCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]