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The map label for this gene is rmlB [C]

Identifier: 190894627

GI number: 190894627

Start: 311950

End: 312996

Strand: Reverse

Name: rmlB [C]

Synonym: RHECIAT_PC0000290

Alternate gene names: 190894627

Gene position: 312996-311950 (Counterclockwise)

Preceding gene: 190894628

Following gene: 190894626

Centisome position: 28.68

GC content: 61.32

Gene sequence:

>1047_bases
ATGCTTCACGTCAATCATCGCCGGAAAGGAAAGACTGCTCTGGTTGCAGGGGGCGCCGGCTTTGTCGGCTCGCATCTCTG
TGATGCTCTTCTCGGCCGCGGCGATACGGTCATCTGCGTCGACAGCTACATTACCGGGTCGCGGGACAATGTGAGGCCGC
TGATGAATCATCCGGGTTTCCGGCTTATCGAAGAGGATATTTGTGCAGTCCTGAAGATCGACGAGCCTCTTGATCAGATC
TACAATCTGGCCTGCGCTGCATCGCCGCCGCAATATCAGGCGGATCCGGTTCATACGATGATGACTTGTGTCGCCGGCAC
GGGCAACCTTCTCGCGTTGGCCGAACAGCACGGGGCATCCTTCCTCCAGGCCTCGACAAGCGAGGTCTATGGCGACCCGG
CCGAGCATCCGCAGCGAGAGGATTATCGCGGCAACGTCAGCTGCACGGGGCCACGCGCCTGCTACGACGAGGGAAAGCGC
GCCGCCGAAGCTCTCTGCTTCGACATGCTGCGGGTCAGGCGCGTCGACGCACGGGTCGCCCGCATCTTCAACACCTATGG
ACCGCGCATGCAGGCCAATGACGGCCGGATCGTCTCAAACCTGATCGCGCAGGCCCTGTCCGGGAAGCCTCTGACCATCT
ATGGAAGCGGCACACAGACGCGATCCTTCTGCTATGTCAGCGATCTTGTCGGTGGTCTCATAGCCCTGATGAACGTGCGG
CCAAACCCCGGCATGCCTGTCAACCTCGGCAATCCTGGGGAGTTCACCATCAATGAGCTTGCCGAGATGGTTCGTTCAAT
GATGGCGGTTCGGACCGTGCTCGCCTACAAGGCGCTGCCGAAGGACGATCCCCAGCGTCGCCGGCCTGATATTTCCCGCG
CGATGGAGCTTCTCGATTGGCAGCCGACGGTACCGCTTGCCGAAGGGCTGCGATATACAATCGACTGGTTTGCCGCCAAT
CTGGACGATCGCCCACGCAAGCGAACAGGAGCGCCTCGCTCTCGTCGCAGAATGGCGGCCTCGCAGGCCGCCTCCCTGGA
GAGCTGA

Upstream 100 bases:

>100_bases
GTCATACGGGGGCTGCGCGTGCTCGCGAATTCGCCCGCGCTCTTTCGCAACTGCCCGCTAATCCAGCTTTGGACCGTATC
TCAGCGTAAGGAGAGTATCG

Downstream 100 bases:

>100_bases
TCGAAAGGCGGATGCACGATGATGAACCCGTCTTTGAAACGGCGTATCAAAGAATTGGGCCCCTGGTTCCATAATATGCG
GCTGGGGGAGACCGAGACCG

Product: dTDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MLHVNHRRKGKTALVAGGAGFVGSHLCDALLGRGDTVICVDSYITGSRDNVRPLMNHPGFRLIEEDICAVLKIDEPLDQI
YNLACAASPPQYQADPVHTMMTCVAGTGNLLALAEQHGASFLQASTSEVYGDPAEHPQREDYRGNVSCTGPRACYDEGKR
AAEALCFDMLRVRRVDARVARIFNTYGPRMQANDGRIVSNLIAQALSGKPLTIYGSGTQTRSFCYVSDLVGGLIALMNVR
PNPGMPVNLGNPGEFTINELAEMVRSMMAVRTVLAYKALPKDDPQRRRPDISRAMELLDWQPTVPLAEGLRYTIDWFAAN
LDDRPRKRTGAPRSRRRMAASQAASLES

Sequences:

>Translated_348_residues
MLHVNHRRKGKTALVAGGAGFVGSHLCDALLGRGDTVICVDSYITGSRDNVRPLMNHPGFRLIEEDICAVLKIDEPLDQI
YNLACAASPPQYQADPVHTMMTCVAGTGNLLALAEQHGASFLQASTSEVYGDPAEHPQREDYRGNVSCTGPRACYDEGKR
AAEALCFDMLRVRRVDARVARIFNTYGPRMQANDGRIVSNLIAQALSGKPLTIYGSGTQTRSFCYVSDLVGGLIALMNVR
PNPGMPVNLGNPGEFTINELAEMVRSMMAVRTVLAYKALPKDDPQRRRPDISRAMELLDWQPTVPLAEGLRYTIDWFAAN
LDDRPRKRTGAPRSRRRMAASQAASLES
>Mature_348_residues
MLHVNHRRKGKTALVAGGAGFVGSHLCDALLGRGDTVICVDSYITGSRDNVRPLMNHPGFRLIEEDICAVLKIDEPLDQI
YNLACAASPPQYQADPVHTMMTCVAGTGNLLALAEQHGASFLQASTSEVYGDPAEHPQREDYRGNVSCTGPRACYDEGKR
AAEALCFDMLRVRRVDARVARIFNTYGPRMQANDGRIVSNLIAQALSGKPLTIYGSGTQTRSFCYVSDLVGGLIALMNVR
PNPGMPVNLGNPGEFTINELAEMVRSMMAVRTVLAYKALPKDDPQRRRPDISRAMELLDWQPTVPLAEGLRYTIDWFAAN
LDDRPRKRTGAPRSRRRMAASQAASLES

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=312, Percent_Identity=53.2051282051282, Blast_Score=348, Evalue=6e-96,
Organism=Homo sapiens, GI7657641, Length=329, Percent_Identity=25.8358662613982, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788589, Length=355, Percent_Identity=26.4788732394366, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788353, Length=352, Percent_Identity=25.8522727272727, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI48994969, Length=352, Percent_Identity=25.8522727272727, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=27.027027027027, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788365, Length=330, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=323, Percent_Identity=51.3931888544892, Blast_Score=330, Evalue=9e-91,
Organism=Caenorhabditis elegans, GI17568069, Length=328, Percent_Identity=25, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=323, Percent_Identity=26.3157894736842, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356223, Length=319, Percent_Identity=52.6645768025078, Blast_Score=335, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38148; Mature: 38148

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHVNHRRKGKTALVAGGAGFVGSHLCDALLGRGDTVICVDSYITGSRDNVRPLMNHPGF
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHCCCCC
RLIEEDICAVLKIDEPLDQIYNLACAASPPQYQADPVHTMMTCVAGTGNLLALAEQHGAS
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHCHH
FLQASTSEVYGDPAEHPQREDYRGNVSCTGPRACYDEGKRAAEALCFDMLRVRRVDARVA
HHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIFNTYGPRMQANDGRIVSNLIAQALSGKPLTIYGSGTQTRSFCYVSDLVGGLIALMNVR
HHHHHCCCCEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
PNPGMPVNLGNPGEFTINELAEMVRSMMAVRTVLAYKALPKDDPQRRRPDISRAMELLDW
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHCC
QPTVPLAEGLRYTIDWFAANLDDRPRKRTGAPRSRRRMAASQAASLES
CCCCCHHHCCCEEHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLHVNHRRKGKTALVAGGAGFVGSHLCDALLGRGDTVICVDSYITGSRDNVRPLMNHPGF
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHCCCCC
RLIEEDICAVLKIDEPLDQIYNLACAASPPQYQADPVHTMMTCVAGTGNLLALAEQHGAS
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHCHH
FLQASTSEVYGDPAEHPQREDYRGNVSCTGPRACYDEGKRAAEALCFDMLRVRRVDARVA
HHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIFNTYGPRMQANDGRIVSNLIAQALSGKPLTIYGSGTQTRSFCYVSDLVGGLIALMNVR
HHHHHCCCCEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
PNPGMPVNLGNPGEFTINELAEMVRSMMAVRTVLAYKALPKDDPQRRRPDISRAMELLDW
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHCC
QPTVPLAEGLRYTIDWFAANLDDRPRKRTGAPRSRRRMAASQAASLES
CCCCCHHHCCCEEHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]