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The map label for this gene is nuoC [H]

Identifier: 190571253

GI number: 190571253

Start: 928305

End: 928880

Strand: Direct

Name: nuoC [H]

Synonym: WPa_0854

Alternate gene names: 190571253

Gene position: 928305-928880 (Clockwise)

Preceding gene: 190571252

Following gene: 190571254

Centisome position: 62.62

GC content: 34.2

Gene sequence:

>576_bases
ATGGATAAAACTGCAAAATACATACAAAAAAAGACTAAATGTGAATGTATTCAGAAAAATGATGGCACTATTGTAATATA
TTCAGCTTTGAATGACATTGAAAATCACTTACTCTTTCTACGTGATGATGAAAAGTGTAGGCTTGAATTATTAGTTGACG
TTTTTGGAGTTGATTACCCAGATAGAGAAAAACGTTTCGAGCTAATATACAATTTGCTCAGCGTTGTACACAATATCAGA
GTGCACATAAAGCTTCAGTTATGTGAAGGTGATATACCTCTAAGTGTAGCAAAGATATTTAACGCAGCTTCGTGGTTTGA
GCGTGAAGTATTTGATATGTATGGAATAGAGTTTTCTGATCACCCAGATTTACGTAGGATTTTAACGGATTATGGATTCA
AAGGTCATCCAATGTTAAAAGATTTTCCTCTCACTGGCTACGAGGAAGTAAGATACGATATAGAGGCAAAAAAGGTTGTA
TATAATCCTATAGACTTACCACAAGATTTTCGTATGTTTGACAGCTTATCCCCTTGGGAAGTTAGTAAAGCCACAAAAGT
AAATATAAAGGAGTAG

Upstream 100 bases:

>100_bases
GTTGATGTGTATGTTCCTGGATGCCCTCCAACTGCTGAGGCGTTGCTATATGGAATGCTATGTCTACAAAATAAAATAAA
ACGAACTAAAAATATATAGC

Downstream 100 bases:

>100_bases
AAAATGACAGCACAAAGAAAAAAAATATCTTTGATTGGTGCAGGAAATATCGGTGGGACTCTTGCCCATATGATTGCACT
AAGAGAGCTAGGAGATGTTA

Product: NADH dehydrogenase I, C subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MDKTAKYIQKKTKCECIQKNDGTIVIYSALNDIENHLLFLRDDEKCRLELLVDVFGVDYPDREKRFELIYNLLSVVHNIR
VHIKLQLCEGDIPLSVAKIFNAASWFEREVFDMYGIEFSDHPDLRRILTDYGFKGHPMLKDFPLTGYEEVRYDIEAKKVV
YNPIDLPQDFRMFDSLSPWEVSKATKVNIKE

Sequences:

>Translated_191_residues
MDKTAKYIQKKTKCECIQKNDGTIVIYSALNDIENHLLFLRDDEKCRLELLVDVFGVDYPDREKRFELIYNLLSVVHNIR
VHIKLQLCEGDIPLSVAKIFNAASWFEREVFDMYGIEFSDHPDLRRILTDYGFKGHPMLKDFPLTGYEEVRYDIEAKKVV
YNPIDLPQDFRMFDSLSPWEVSKATKVNIKE
>Mature_191_residues
MDKTAKYIQKKTKCECIQKNDGTIVIYSALNDIENHLLFLRDDEKCRLELLVDVFGVDYPDREKRFELIYNLLSVVHNIR
VHIKLQLCEGDIPLSVAKIFNAASWFEREVFDMYGIEFSDHPDLRRILTDYGFKGHPMLKDFPLTGYEEVRYDIEAKKVV
YNPIDLPQDFRMFDSLSPWEVSKATKVNIKE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=181, Percent_Identity=47.5138121546961, Blast_Score=169, Evalue=2e-42,
Organism=Escherichia coli, GI145693162, Length=129, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71990788, Length=148, Percent_Identity=51.3513513513513, Blast_Score=161, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI32563621, Length=148, Percent_Identity=51.3513513513513, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24656494, Length=176, Percent_Identity=47.1590909090909, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22488; Mature: 22488

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTAKYIQKKTKCECIQKNDGTIVIYSALNDIENHLLFLRDDEKCRLELLVDVFGVDYP
CCHHHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHCEEEEECCCHHHHHHHHHHHCCCCC
DREKRFELIYNLLSVVHNIRVHIKLQLCEGDIPLSVAKIFNAASWFEREVFDMYGIEFSD
CHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
HPDLRRILTDYGFKGHPMLKDFPLTGYEEVRYDIEAKKVVYNPIDLPQDFRMFDSLSPWE
CHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEECCCCCEEEECCCCCCHHHHHHCCCCCCC
VSKATKVNIKE
CCCCCEEECCC
>Mature Secondary Structure
MDKTAKYIQKKTKCECIQKNDGTIVIYSALNDIENHLLFLRDDEKCRLELLVDVFGVDYP
CCHHHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHCEEEEECCCHHHHHHHHHHHCCCCC
DREKRFELIYNLLSVVHNIRVHIKLQLCEGDIPLSVAKIFNAASWFEREVFDMYGIEFSD
CHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
HPDLRRILTDYGFKGHPMLKDFPLTGYEEVRYDIEAKKVVYNPIDLPQDFRMFDSLSPWE
CHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEECCCCCEEEECCCCCCHHHHHHCCCCCCC
VSKATKVNIKE
CCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA