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The map label for this gene is argB

Identifier: 18978056

GI number: 18978056

Start: 1565708

End: 1566457

Strand: Direct

Name: argB

Synonym: PF1684

Alternate gene names: 18978056

Gene position: 1565708-1566457 (Clockwise)

Preceding gene: 18978055

Following gene: 18978057

Centisome position: 82.05

GC content: 39.6

Gene sequence:

>750_bases
ATGAGAGTCGTGAAGATTGGAGGTTCCGTTATATCAATGCTAGAAAATCTATGGAGAGAAAACGGAATCTCAGAAATTCT
GGGAAATTCAGTTATTGTTCATGGAGGATCAAGACATGTTGATGAACTTTCCAGGAAAATGGGAGTTAAAATAGAGAAGC
TAACAAGCCCCTCTGGGGTAACCTTTAGAAGAACAACAAAGGAAGTGCTTAAGGTTTATGTAGCCGCAATGATAAGGGCC
AATAAAGAAATTGTTGAATTCTTGAGAAATCAAGGAATAAACGCAATAGGCCTCACAGGACTTGACAGGGAGCTGATTAT
TGGAGAGAGGAAAAAGCTAATCAAAGCAGTTATCAATGGAAGAGTTGTTGCCATTAGGGATGATTATTCTGGAGTAATAA
AGAAAGTGAACACTCAAATCCTAAGAGAGTATCTCAAGATTGGAACTCCAGTTATAGCTTCCATTGCCTATGACCCAATT
GAGAACACTCCCCTCAACGTAGATGGTGATAAAGTTGCTTATCATGTGGCCCTCGCCATGGATGCAAAGGAGCTCTACTT
CCTCTCAGACACAGCATTTATGGCTGGAGGAAAAGTAGTTTCAGAGCTCCCTGCAGATGAAATAGAGAAATACTTAATTT
TTGCAAAGGGAGGAATGAAAAAGAAGCTTCTTATGGCCAAAGAAGCGATAAACAGTGGTATTAAGAACGTTGTAATTGAA
GGATTAAACGGAAGGACGGTGATATATTGA

Upstream 100 bases:

>100_bases
GGAGCTGGACAGGCTGTTCAAAACATGAACATAATGTTTGGACTTAAAGAAACGACTGGATTAGAGTATTATCCTGTTTA
TCCCGTGTGAGGTGGTAACA

Downstream 100 bases:

>100_bases
GGGAAATGAGCTTGTACAGGAAGAGACTAAGGCTCGTAAAAGGAGAAGGAATTTACGTATGGGATTCCCAGGGAAAGAAG
TACATAGACTTAATAGCAGG

Product: acetylglutamate/acetylaminoadipate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate/N-acetyl-L-aminoadipate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MRVVKIGGSVISMLENLWRENGISEILGNSVIVHGGSRHVDELSRKMGVKIEKLTSPSGVTFRRTTKEVLKVYVAAMIRA
NKEIVEFLRNQGINAIGLTGLDRELIIGERKKLIKAVINGRVVAIRDDYSGVIKKVNTQILREYLKIGTPVIASIAYDPI
ENTPLNVDGDKVAYHVALAMDAKELYFLSDTAFMAGGKVVSELPADEIEKYLIFAKGGMKKKLLMAKEAINSGIKNVVIE
GLNGRTVIY

Sequences:

>Translated_249_residues
MRVVKIGGSVISMLENLWRENGISEILGNSVIVHGGSRHVDELSRKMGVKIEKLTSPSGVTFRRTTKEVLKVYVAAMIRA
NKEIVEFLRNQGINAIGLTGLDRELIIGERKKLIKAVINGRVVAIRDDYSGVIKKVNTQILREYLKIGTPVIASIAYDPI
ENTPLNVDGDKVAYHVALAMDAKELYFLSDTAFMAGGKVVSELPADEIEKYLIFAKGGMKKKLLMAKEAINSGIKNVVIE
GLNGRTVIY
>Mature_249_residues
MRVVKIGGSVISMLENLWRENGISEILGNSVIVHGGSRHVDELSRKMGVKIEKLTSPSGVTFRRTTKEVLKVYVAAMIRA
NKEIVEFLRNQGINAIGLTGLDRELIIGERKKLIKAVINGRVVAIRDDYSGVIKKVNTQILREYLKIGTPVIASIAYDPI
ENTPLNVDGDKVAYHVALAMDAKELYFLSDTAFMAGGKVVSELPADEIEKYLIFAKGGMKKKLLMAKEAINSGIKNVVIE
GLNGRTVIY

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_PYRFU (Q8U0B5)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579413.1
- ProteinModelPortal:   Q8U0B5
- EnsemblBacteria:   EBPYRT00000004768
- GeneID:   1469561
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1684
- NMPDR:   fig|186497.1.peg.1732
- GeneTree:   EBGT00050000022350
- HOGENOM:   HBG497643
- OMA:   YLPVLTP
- ProtClustDB:   PRK14058
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_A
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 27399; Mature: 27399

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: BINDING 63-63 BINDING 166-166

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVKIGGSVISMLENLWRENGISEILGNSVIVHGGSRHVDELSRKMGVKIEKLTSPSGV
CEEEEECCHHHHHHHHHHHHCCHHHHHCCCEEEECCCCCHHHHHHHHCCEEEEECCCCCC
TFRRTTKEVLKVYVAAMIRANKEIVEFLRNQGINAIGLTGLDRELIIGERKKLIKAVING
EEHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
RVVAIRDDYSGVIKKVNTQILREYLKIGTPVIASIAYDPIENTPLNVDGDKVAYHVALAM
CEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEE
DAKELYFLSDTAFMAGGKVVSELPADEIEKYLIFAKGGMKKKLLMAKEAINSGIKNVVIE
CHHHEEEEECCHHHHCCHHHHHCCHHHHHHEEEEECCCCHHHHHHHHHHHHCCHHHHEEE
GLNGRTVIY
CCCCCEEEC
>Mature Secondary Structure
MRVVKIGGSVISMLENLWRENGISEILGNSVIVHGGSRHVDELSRKMGVKIEKLTSPSGV
CEEEEECCHHHHHHHHHHHHCCHHHHHCCCEEEECCCCCHHHHHHHHCCEEEEECCCCCC
TFRRTTKEVLKVYVAAMIRANKEIVEFLRNQGINAIGLTGLDRELIIGERKKLIKAVING
EEHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
RVVAIRDDYSGVIKKVNTQILREYLKIGTPVIASIAYDPIENTPLNVDGDKVAYHVALAM
CEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEE
DAKELYFLSDTAFMAGGKVVSELPADEIEKYLIFAKGGMKKKLLMAKEAINSGIKNVVIE
CHHHEEEEECCHHHHCCHHHHHCCHHHHHHEEEEECCCCHHHHHHHHHHHHCCHHHHEEE
GLNGRTVIY
CCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA