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The map label for this gene is argC

Identifier: 18978055

GI number: 18978055

Start: 1564705

End: 1565697

Strand: Direct

Name: argC

Synonym: PF1683

Alternate gene names: 18978055

Gene position: 1564705-1565697 (Clockwise)

Preceding gene: 18978054

Following gene: 18978056

Centisome position: 82.0

GC content: 42.3

Gene sequence:

>993_bases
ATGATCAAGGCTGCTGTTGTTGGGGCTAGTGGATATATCGGAGGGGAATTAGTTAGGTTACTCGCAATGCATCCAGAAGT
TGAGATTACTGCAATAACCTCAAGACAATATGCCGGAAAGAAAGTGCATAAAGTTCATCCAAACCTTAGAGGACTTGACT
TAAGATTCACAAACGACTACAATTTCGATGCAGATGTGATATTCTTGGCAGTCCCACATGGGACATCTATGAAAATCATA
GAGGAGTTCTTGGGAAGTGCTAAGATAATAGACATGAGCGCTGATTTCAGGATAAAGAAAGAGTTGTACGAAAAGTATTA
TGGTCCGCACGAGAAACCCGAACTCATAGACAGATTTACTTACGGCTTACCAGAGCTTCACAGAAAAGAAATAAAAAAGG
CCGAACTTGTTGCCAATCCAGGGTGTAATGCCACAGCAACGATCCTTGGACTCTATCCCTTCAAGGACTTAACTCAGGAG
GCCATAGTTGACCTAAAAGTCAGCTCCTCTGCAGGAGGAAGAAGAGAGAACATTGCAAGTATTCATCCAGAAAGAAGCAA
CGTGGTTAGGGTATACAAGCCCTATCACCACAGGCACGAGGCAGAGGTTCTGCAGGAAACTAGAGTAAAGGCCATGTTCA
CAGTCCATTCTGTAGACTTAGTGAGAGGATTGTTAGCTACAATTTACTTCCGCTATGAGGGCAATGAAAGAGAACTGCTG
AGAAAGCTCTTGATGTATAAAGACGAGCCCTTTGTAAGAATCGTAACTGATAAAGGAGGATTACAAAGGTATCCTGATCC
AAAGTACGTCATTGGAAGCAATTTTATCGATATAGGATTCGCATACGACTCCGAAAACTCAAGGGTGATGGTATTCTCGG
CAATAGATAACTTGATCAAGGGAGGAGCTGGACAGGCTGTTCAAAACATGAACATAATGTTTGGACTTAAAGAAACGACT
GGATTAGAGTATTATCCTGTTTATCCCGTGTGA

Upstream 100 bases:

>100_bases
ACGAAGTTAATCCAAATATGGAGTTTAAGAACGCAGCCAGAGTTACTGGAGTTGATATTGCTCGAAAACTCGTTGAATAT
GCAGTGGAGGTGGCAAAGAG

Downstream 100 bases:

>100_bases
GGTGGTAACAATGAGAGTCGTGAAGATTGGAGGTTCCGTTATATCAATGCTAGAAAATCTATGGAGAGAAAACGGAATCT
CAGAAATTCTGGGAAATTCA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde/N-acetyl-aminoadipate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIKAAVVGASGYIGGELVRLLAMHPEVEITAITSRQYAGKKVHKVHPNLRGLDLRFTNDYNFDADVIFLAVPHGTSMKII
EEFLGSAKIIDMSADFRIKKELYEKYYGPHEKPELIDRFTYGLPELHRKEIKKAELVANPGCNATATILGLYPFKDLTQE
AIVDLKVSSSAGGRRENIASIHPERSNVVRVYKPYHHRHEAEVLQETRVKAMFTVHSVDLVRGLLATIYFRYEGNERELL
RKLLMYKDEPFVRIVTDKGGLQRYPDPKYVIGSNFIDIGFAYDSENSRVMVFSAIDNLIKGGAGQAVQNMNIMFGLKETT
GLEYYPVYPV

Sequences:

>Translated_330_residues
MIKAAVVGASGYIGGELVRLLAMHPEVEITAITSRQYAGKKVHKVHPNLRGLDLRFTNDYNFDADVIFLAVPHGTSMKII
EEFLGSAKIIDMSADFRIKKELYEKYYGPHEKPELIDRFTYGLPELHRKEIKKAELVANPGCNATATILGLYPFKDLTQE
AIVDLKVSSSAGGRRENIASIHPERSNVVRVYKPYHHRHEAEVLQETRVKAMFTVHSVDLVRGLLATIYFRYEGNERELL
RKLLMYKDEPFVRIVTDKGGLQRYPDPKYVIGSNFIDIGFAYDSENSRVMVFSAIDNLIKGGAGQAVQNMNIMFGLKETT
GLEYYPVYPV
>Mature_330_residues
MIKAAVVGASGYIGGELVRLLAMHPEVEITAITSRQYAGKKVHKVHPNLRGLDLRFTNDYNFDADVIFLAVPHGTSMKII
EEFLGSAKIIDMSADFRIKKELYEKYYGPHEKPELIDRFTYGLPELHRKEIKKAELVANPGCNATATILGLYPFKDLTQE
AIVDLKVSSSAGGRRENIASIHPERSNVVRVYKPYHHRHEAEVLQETRVKAMFTVHSVDLVRGLLATIYFRYEGNERELL
RKLLMYKDEPFVRIVTDKGGLQRYPDPKYVIGSNFIDIGFAYDSENSRVMVFSAIDNLIKGGAGQAVQNMNIMFGLKETT
GLEYYPVYPV

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=342, Percent_Identity=36.5497076023392, Blast_Score=182, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6320913, Length=336, Percent_Identity=28.8690476190476, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_PYRFU (Q8U0B6)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579412.1
- ProteinModelPortal:   Q8U0B6
- SMR:   Q8U0B6
- EnsemblBacteria:   EBPYRT00000004963
- GeneID:   1469560
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1683
- NMPDR:   fig|186497.1.peg.1731
- GeneTree:   EBGT00050000022773
- HOGENOM:   HBG294213
- OMA:   GCMATAS
- ProtClustDB:   PRK00436
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37350; Mature: 37350

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAAVVGASGYIGGELVRLLAMHPEVEITAITSRQYAGKKVHKVHPNLRGLDLRFTNDY
CCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEECCCCCCEEEEEECCCC
NFDADVIFLAVPHGTSMKIIEEFLGSAKIIDMSADFRIKKELYEKYYGPHEKPELIDRFT
CCCCCEEEEEECCCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHH
YGLPELHRKEIKKAELVANPGCNATATILGLYPFKDLTQEAIVDLKVSSSAGGRRENIAS
CCCCHHHHHHHHHHHEECCCCCCCEEEEEEECCCHHHHHHHHEEEEECCCCCCCCCCCCC
IHPERSNVVRVYKPYHHRHEAEVLQETRVKAMFTVHSVDLVRGLLATIYFRYEGNERELL
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHEEEEEECCHHHHH
RKLLMYKDEPFVRIVTDKGGLQRYPDPKYVIGSNFIDIGFAYDSENSRVMVFSAIDNLIK
HHHHHCCCCCEEEEEECCCCCCCCCCCCEEECCCEEEEEEEEECCCCEEEEEHHHHHHHC
GGAGQAVQNMNIMFGLKETTGLEYYPVYPV
CCCCCHHHCCEEEEEEHHCCCCEEEECCCC
>Mature Secondary Structure
MIKAAVVGASGYIGGELVRLLAMHPEVEITAITSRQYAGKKVHKVHPNLRGLDLRFTNDY
CCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEECCCCCCEEEEEECCCC
NFDADVIFLAVPHGTSMKIIEEFLGSAKIIDMSADFRIKKELYEKYYGPHEKPELIDRFT
CCCCCEEEEEECCCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHH
YGLPELHRKEIKKAELVANPGCNATATILGLYPFKDLTQEAIVDLKVSSSAGGRRENIAS
CCCCHHHHHHHHHHHEECCCCCCCEEEEEEECCCHHHHHHHHEEEEECCCCCCCCCCCCC
IHPERSNVVRVYKPYHHRHEAEVLQETRVKAMFTVHSVDLVRGLLATIYFRYEGNERELL
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHEEEEEECCHHHHH
RKLLMYKDEPFVRIVTDKGGLQRYPDPKYVIGSNFIDIGFAYDSENSRVMVFSAIDNLIK
HHHHHCCCCCEEEEEECCCCCCCCCCCCEEECCCEEEEEEEEECCCCEEEEEHHHHHHHC
GGAGQAVQNMNIMFGLKETTGLEYYPVYPV
CCCCCHHHCCEEEEEEHHCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA