Click here to switch to the map view.

The map label for this gene is ygbD [C]

Identifier: 18977904

GI number: 18977904

Start: 1429318

End: 1430634

Strand: Direct

Name: ygbD [C]

Synonym: PF1532

Alternate gene names: 18977904

Gene position: 1429318-1430634 (Clockwise)

Preceding gene: 18977903

Following gene: 18977905

Centisome position: 74.9

GC content: 41.69

Gene sequence:

>1317_bases
ATGAGAATAGTTGTTATAGGTTCGGGAACTGCAGGAAGCAACTTTGCACTTTTTATGAGGAAATTGGACAGAAAAGCCGA
GATAACAGTAATTGGAAAAGAAGAAACAATGCAATATTCTCCCTGCGCTTTGCCTCACGTCATAAGCGGAGTTATAGAAA
AGCCCGAAGATGTAATAGTTTTCCCCAATGAATTTTATGAAAAGCAGAGAATTAAGCTCCTCCTAAACACTGAAGCTAAG
AAAATAGACAGGGAAAGGAAAGTCGTTGTCACTGATAAGGGTGAAATTCCATACGACAAGCTTGTTATAGCAACAGGTTC
TAAGGCTTTTGTCCCTCCAATAAAGGGAGTAGAAAATGAGGGAGTTTTCACACTGAAGAGCCTAGAAGATGTCCGAAAGA
TAAAGGAGTTTATTAAAAAGAGAAATCCAAAGAACGCCGTTGTGATCGGCGCGGGTTTAATTGGGCTGGAAGGAGCCGAA
GCTTTCGCAAAGCTAGGAATGAAGGTTACAGTTGTTGAGCTTTTAGAGCACCTCTTGCCCACCATGCTGGACAAAGATAT
TGCTAAAATAGTCGAAGAAAACATGAGAAAGTACGGAGTAGACTTCAAATTTGGAGTTGGAGTGGATGAAATAATAGGAG
ATCCAGTGGAAAAAGTAAAAGTGGGAGAGGAGGAAATCGACGCTGATATAGTTCTTGTAGCTACTGGTGTTAGGGCGAAT
GTAGAGTTAGCCAAAGAGGCAGGACTTGAGGTCAACAGGGGAATAGTCGTAAATGAATACCTCCAAACTAGTGACCCAGA
TATCTATGCAATAGGAGACTGTGCTGAGGTTATAGATGCAGTCACTGGAAAAAGAACTCTCAGCCAACTTGGAACTTCAG
CAGTTAGAATGGCAAAAGTTGCTGCAGAGAACATAGCTGGGAGAAATGTGAAGTTTAGACCAGTATTCAACACTGCCATA
ACTGAGATCTTTGATCTTGAAATTGGAGCCTTTGGTATTACAGAGGAGAGGGCCAAGAAGGAGGAAATCGAAGTGGTTGT
AGGAAAATTCAGAGGTTCAACGAAACCTGAATACTACCCAGGAGGAAAGCCGATAGTTGTTAAGTTAATCTTTAGGAAAG
AAGACAGAAGACTAATAGGTGCTCAAATAGTGGGCGGAGAAAGAGTTTGGGGGAGAATAATGACACTTTCTGCATTAGCC
CAGAAAGGAGCTACCGTTGAAGATGTTGTCTATCTTGAAACTGCCTATGCTCCTCCAATAAGCCCAACTATAGATCCAAT
TACGATAGCAGCTGAGATGGCTATGAGAAAGTTATGA

Upstream 100 bases:

>100_bases
AACAAATGCTAATTTTTCACCTCCAATACTGTGATTTTTTGGATTTTTTAAAGATTAAATATTTAATGTCACTCAAACTT
TATTATCTCTTGGTGGTCGA

Downstream 100 bases:

>100_bases
TAACCTGGGCTTCTTTTGTATTATTTTTTTGGTGATTTTTATGGAGGATTGATTAACCTCTCAAGGTTATGAAGGTCAAA
ACTTAAATACCTGTATTACT

Product: NADH oxidase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MRIVVIGSGTAGSNFALFMRKLDRKAEITVIGKEETMQYSPCALPHVISGVIEKPEDVIVFPNEFYEKQRIKLLLNTEAK
KIDRERKVVVTDKGEIPYDKLVIATGSKAFVPPIKGVENEGVFTLKSLEDVRKIKEFIKKRNPKNAVVIGAGLIGLEGAE
AFAKLGMKVTVVELLEHLLPTMLDKDIAKIVEENMRKYGVDFKFGVGVDEIIGDPVEKVKVGEEEIDADIVLVATGVRAN
VELAKEAGLEVNRGIVVNEYLQTSDPDIYAIGDCAEVIDAVTGKRTLSQLGTSAVRMAKVAAENIAGRNVKFRPVFNTAI
TEIFDLEIGAFGITEERAKKEEIEVVVGKFRGSTKPEYYPGGKPIVVKLIFRKEDRRLIGAQIVGGERVWGRIMTLSALA
QKGATVEDVVYLETAYAPPISPTIDPITIAAEMAMRKL

Sequences:

>Translated_438_residues
MRIVVIGSGTAGSNFALFMRKLDRKAEITVIGKEETMQYSPCALPHVISGVIEKPEDVIVFPNEFYEKQRIKLLLNTEAK
KIDRERKVVVTDKGEIPYDKLVIATGSKAFVPPIKGVENEGVFTLKSLEDVRKIKEFIKKRNPKNAVVIGAGLIGLEGAE
AFAKLGMKVTVVELLEHLLPTMLDKDIAKIVEENMRKYGVDFKFGVGVDEIIGDPVEKVKVGEEEIDADIVLVATGVRAN
VELAKEAGLEVNRGIVVNEYLQTSDPDIYAIGDCAEVIDAVTGKRTLSQLGTSAVRMAKVAAENIAGRNVKFRPVFNTAI
TEIFDLEIGAFGITEERAKKEEIEVVVGKFRGSTKPEYYPGGKPIVVKLIFRKEDRRLIGAQIVGGERVWGRIMTLSALA
QKGATVEDVVYLETAYAPPISPTIDPITIAAEMAMRKL
>Mature_438_residues
MRIVVIGSGTAGSNFALFMRKLDRKAEITVIGKEETMQYSPCALPHVISGVIEKPEDVIVFPNEFYEKQRIKLLLNTEAK
KIDRERKVVVTDKGEIPYDKLVIATGSKAFVPPIKGVENEGVFTLKSLEDVRKIKEFIKKRNPKNAVVIGAGLIGLEGAE
AFAKLGMKVTVVELLEHLLPTMLDKDIAKIVEENMRKYGVDFKFGVGVDEIIGDPVEKVKVGEEEIDADIVLVATGVRAN
VELAKEAGLEVNRGIVVNEYLQTSDPDIYAIGDCAEVIDAVTGKRTLSQLGTSAVRMAKVAAENIAGRNVKFRPVFNTAI
TEIFDLEIGAFGITEERAKKEEIEVVVGKFRGSTKPEYYPGGKPIVVKLIFRKEDRRLIGAQIVGGERVWGRIMTLSALA
QKGATVEDVVYLETAYAPPISPTIDPITIAAEMAMRKL

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=327, Percent_Identity=26.2996941896024, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI65787454, Length=327, Percent_Identity=26.2996941896024, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI21389617, Length=327, Percent_Identity=26.2996941896024, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI91199540, Length=379, Percent_Identity=31.3984168865435, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI291045266, Length=339, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789065, Length=318, Percent_Identity=33.0188679245283, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1789765, Length=405, Percent_Identity=30.6172839506173, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1788892, Length=275, Percent_Identity=28.3636363636364, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786307, Length=358, Percent_Identity=31.0055865921788, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787352, Length=330, Percent_Identity=28.4848484848485, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082354, Length=334, Percent_Identity=25.4491017964072, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081717, Length=299, Percent_Identity=29.0969899665552, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32565766, Length=351, Percent_Identity=28.7749287749288, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17559934, Length=391, Percent_Identity=26.8542199488491, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32564386, Length=388, Percent_Identity=27.319587628866, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321091, Length=360, Percent_Identity=27.5, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281359715, Length=330, Percent_Identity=27.5757575757576, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281359713, Length=330, Percent_Identity=27.5757575757576, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24639250, Length=330, Percent_Identity=27.5757575757576, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI18543267, Length=330, Percent_Identity=27.5757575757576, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24639252, Length=330, Percent_Identity=27.5757575757576, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24639257, Length=330, Percent_Identity=27.5757575757576, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24585130, Length=334, Percent_Identity=24.5508982035928, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21358499, Length=395, Percent_Identity=30.126582278481, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 48072; Mature: 48072

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVVIGSGTAGSNFALFMRKLDRKAEITVIGKEETMQYSPCALPHVISGVIEKPEDVIV
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECHHCCCCCCCCHHHHHHHHHCCCCCEEE
FPNEFYEKQRIKLLLNTEAKKIDRERKVVVTDKGEIPYDKLVIATGSKAFVPPIKGVENE
CCHHHHCCCCEEEEECCCHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCC
GVFTLKSLEDVRKIKEFIKKRNPKNAVVIGAGLIGLEGAEAFAKLGMKVTVVELLEHLLP
CEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECEECCCCHHHHHHCCCEEEHHHHHHHHHH
TMLDKDIAKIVEENMRKYGVDFKFGVGVDEIIGDPVEKVKVGEEEIDADIVLVATGVRAN
HHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHCCCHHHHCCCHHHCCCCEEEEEECCCCC
VELAKEAGLEVNRGIVVNEYLQTSDPDIYAIGDCAEVIDAVTGKRTLSQLGTSAVRMAKV
CHHHHHCCCEECCCEEEEHHHCCCCCCEEEECCHHHHHHHHHCHHHHHHHCHHHHHHHHH
AAENIAGRNVKFRPVFNTAITEIFDLEIGAFGITEERAKKEEIEVVVGKFRGSTKPEYYP
HHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEHHCCCCCCCCCC
GGKPIVVKLIFRKEDRRLIGAQIVGGERVWGRIMTLSALAQKGATVEDVVYLETAYAPPI
CCCEEEEEEEEECCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCC
SPTIDPITIAAEMAMRKL
CCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRIVVIGSGTAGSNFALFMRKLDRKAEITVIGKEETMQYSPCALPHVISGVIEKPEDVIV
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECHHCCCCCCCCHHHHHHHHHCCCCCEEE
FPNEFYEKQRIKLLLNTEAKKIDRERKVVVTDKGEIPYDKLVIATGSKAFVPPIKGVENE
CCHHHHCCCCEEEEECCCHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCC
GVFTLKSLEDVRKIKEFIKKRNPKNAVVIGAGLIGLEGAEAFAKLGMKVTVVELLEHLLP
CEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECEECCCCHHHHHHCCCEEEHHHHHHHHHH
TMLDKDIAKIVEENMRKYGVDFKFGVGVDEIIGDPVEKVKVGEEEIDADIVLVATGVRAN
HHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHCCCHHHHCCCHHHCCCCEEEEEECCCCC
VELAKEAGLEVNRGIVVNEYLQTSDPDIYAIGDCAEVIDAVTGKRTLSQLGTSAVRMAKV
CHHHHHCCCEECCCEEEEHHHCCCCCCEEEECCHHHHHHHHHCHHHHHHHCHHHHHHHHH
AAENIAGRNVKFRPVFNTAITEIFDLEIGAFGITEERAKKEEIEVVVGKFRGSTKPEYYP
HHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEHHCCCCCCCCCC
GGKPIVVKLIFRKEDRRLIGAQIVGGERVWGRIMTLSALAQKGATVEDVVYLETAYAPPI
CCCEEEEEEEEECCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCC
SPTIDPITIAAEMAMRKL
CCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]