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The map label for this gene is chiA [H]

Identifier: 18977605

GI number: 18977605

Start: 1166614

End: 1168767

Strand: Reverse

Name: chiA [H]

Synonym: PF1233

Alternate gene names: 18977605

Gene position: 1168767-1166614 (Counterclockwise)

Preceding gene: 18977606

Following gene: 18977603

Centisome position: 61.25

GC content: 44.38

Gene sequence:

>2154_bases
ATGAAATATCTCGACTTCATCAATGTAATGACATATGATTATCATGGAGCCTGGGATCCAATTACCGGACACTTAGCTCC
ATTGTATGCCGATCCGAATGCTCCTTATGAGGATCCAAATATAAAGTGGAACTTCAATGTAAACGCCTCCATTCAATGGT
ACCTAAAGCATGGAGTCAATCCAAAACAGTTAGGCTTGGGACTCCCATTCTATGGAAGAAGCTTTGCAAATGTTCCCCCA
GAGAACAATGGATTATACCAGCCTTTCAGTGGAACACCAGCCGGAACTTGGGGGCCTGCATATGAAACCCATGGAGTTAT
GGACTATTGGGATATTGAAGAGAAGAGGGCAAGCGGACAATACAACTACTACTGGGATCCAGTTGCAATGGTTCCCTGGT
TATATTCTCCAAGCCTTAAGATCTTCATAAGTTATGATGATAAGAAGAGCATTGGAATAAAAGTAGACTATGCCCTCAAG
TATAACCTGGGAGGAGTAATGGTTTGGGAGATAACTGCAGACAGAAAGCCTGGAACGAACTCTCACCCATTGCTGGATAC
AATATTAGAGCATATAGCCCAGGGAGGAGGAGTTGTTCCAACACCATCACCAACTCCAACCCCAACTCCCACACCCACTC
CAACACCAACAACCACGACAACCACTTCCACACCAACTCCTACAACTACCACCACACCATCACCAACAACTACTACAACC
ACAACGACTACCACGACAACAACATCCACAACCACAACGCCAACCACTACAACTACCCCTGTCCCAGTCTCAGGATCTCT
AGAGGTAAAGGTAAACGATTGGGGTAGTGGTGCTGAGTATGATGTGACTCTTAATTTGGATGGACAGTATGACTGGACTG
TGAAGGTTAAACTAGCCCCAGGAGCCACTGTAGGAAGCTTCTGGAGCGCTAACAAACAAGAGGGGAATGGCTATGTCATC
TTCACTCCAGTAAGCTGGAATAAAGGGCCGACAGCAACATTTGGATTCATAGTAAACGGACCACAAGGAGACAAAGTAGA
AGAAATAACCCTAGAAATAAACGGACAAGTAATTGACATATGGACACCAACCGGAGGGACAACTCCCACACCCACTACCA
CAACCACATCTACCCCAACTCCCTCACAAACTCCAACGCCAACTCCCACACCCACCCCAACTCCTACTCCTACCCCGACT
CTAACTCCTACGCCACTTCCTGGGAATGCAAATCCAATACCAGAACACTTCTTTGCTCCCTATATCGATATGAGTCTATC
AGTACACAAGCCCTTAGTAGAATATGCAAAGTTAACTGGAACTAAGTACTTTACCTTGGCATTCATTCTCTATAGTTCAG
TTTACAACGGTCCAGCTTGGGCAGGCTCAATTCCTCTAGAGAAATTTGTTGATGAGGTAAGAGAACTCAGAGAAATTGGT
GGAGAAGTAATAATAGCGTTTGGTGGGGCTGTAGGACCATATCTTTGCCAACAGGCCAGCACGCCAGAACAATTGGCTGA
ATGGTACATAAAGGTAATTGATACATATAATGCCACTTACTTGGACTTTGACATAGAAGCCGGTATCGATGCAGATAAAC
TTGCAGATGCCCTACTCATAGTCCAAAGAGAAAGACCTTGGGTAAAATTCAGCTTTACCTTACCCAGCGATCCGGGGATA
GGACTAGCAGGAGGATACGGTATAATAGAAACGATGGCCAAGAAGGGGGTAAGAGTAGATAGAGTCAATCCAATGACGAT
GGATTACTACTGGACTCCTTCTAACGCAGAAAATGCAATCAAGGTAGCTGAAAATGTGTTCAGACAATTAAAGCAGATTT
ATCCCGAAAAAAGTGATGAAGAAATTTGGAAGATGATAGGATTAACTCCAATGATAGGAGTAAATGATGACAAGAGTGTG
TTTACATTAGAAGATGCTCAGCAACTTGTTGACTGGGCAATTCAACATAAAATAGGATCACTAGCCTTCTGGAGTGTAGA
CAGAGACCACCCAGGACCAACAGGAGAAGTTTCACCACTCCACAGAGGAACAAATGACCCAGATTGGGCGTTTAGCCACG
TATTCGTAAAATTCATGGAGGCATTTGGATACACATTCTCCGCTCAAACTAGCGAAGCTAGTGTTCCAACATAA

Upstream 100 bases:

>100_bases
TTTGATCAAGCCGAATTAGAAGATAAAAAAAGAGTATCTCCTAACTGCAGCAGTTCCAGCTGATCCAGTTAAAGCTGCAA
GAATAAATTGGACTGAGGCT

Downstream 100 bases:

>100_bases
TTTTTCCACCCTCTCTATAATTATTTTATTTATTTTTGTTGTTCTCGAAACTCACAGCAGGAATAATTGAATGAGGTACA
GTAAACCTCACATGAAGTCA

Product: putative chitinase

Products: NA

Alternate protein names: Chitinase; Lysozyme [H]

Number of amino acids: Translated: 717; Mature: 717

Protein sequence:

>717_residues
MKYLDFINVMTYDYHGAWDPITGHLAPLYADPNAPYEDPNIKWNFNVNASIQWYLKHGVNPKQLGLGLPFYGRSFANVPP
ENNGLYQPFSGTPAGTWGPAYETHGVMDYWDIEEKRASGQYNYYWDPVAMVPWLYSPSLKIFISYDDKKSIGIKVDYALK
YNLGGVMVWEITADRKPGTNSHPLLDTILEHIAQGGGVVPTPSPTPTPTPTPTPTPTTTTTTSTPTPTTTTTPSPTTTTT
TTTTTTTTSTTTTPTTTTTPVPVSGSLEVKVNDWGSGAEYDVTLNLDGQYDWTVKVKLAPGATVGSFWSANKQEGNGYVI
FTPVSWNKGPTATFGFIVNGPQGDKVEEITLEINGQVIDIWTPTGGTTPTPTTTTTSTPTPSQTPTPTPTPTPTPTPTPT
LTPTPLPGNANPIPEHFFAPYIDMSLSVHKPLVEYAKLTGTKYFTLAFILYSSVYNGPAWAGSIPLEKFVDEVRELREIG
GEVIIAFGGAVGPYLCQQASTPEQLAEWYIKVIDTYNATYLDFDIEAGIDADKLADALLIVQRERPWVKFSFTLPSDPGI
GLAGGYGIIETMAKKGVRVDRVNPMTMDYYWTPSNAENAIKVAENVFRQLKQIYPEKSDEEIWKMIGLTPMIGVNDDKSV
FTLEDAQQLVDWAIQHKIGSLAFWSVDRDHPGPTGEVSPLHRGTNDPDWAFSHVFVKFMEAFGYTFSAQTSEASVPT

Sequences:

>Translated_717_residues
MKYLDFINVMTYDYHGAWDPITGHLAPLYADPNAPYEDPNIKWNFNVNASIQWYLKHGVNPKQLGLGLPFYGRSFANVPP
ENNGLYQPFSGTPAGTWGPAYETHGVMDYWDIEEKRASGQYNYYWDPVAMVPWLYSPSLKIFISYDDKKSIGIKVDYALK
YNLGGVMVWEITADRKPGTNSHPLLDTILEHIAQGGGVVPTPSPTPTPTPTPTPTPTTTTTTSTPTPTTTTTPSPTTTTT
TTTTTTTTSTTTTPTTTTTPVPVSGSLEVKVNDWGSGAEYDVTLNLDGQYDWTVKVKLAPGATVGSFWSANKQEGNGYVI
FTPVSWNKGPTATFGFIVNGPQGDKVEEITLEINGQVIDIWTPTGGTTPTPTTTTTSTPTPSQTPTPTPTPTPTPTPTPT
LTPTPLPGNANPIPEHFFAPYIDMSLSVHKPLVEYAKLTGTKYFTLAFILYSSVYNGPAWAGSIPLEKFVDEVRELREIG
GEVIIAFGGAVGPYLCQQASTPEQLAEWYIKVIDTYNATYLDFDIEAGIDADKLADALLIVQRERPWVKFSFTLPSDPGI
GLAGGYGIIETMAKKGVRVDRVNPMTMDYYWTPSNAENAIKVAENVFRQLKQIYPEKSDEEIWKMIGLTPMIGVNDDKSV
FTLEDAQQLVDWAIQHKIGSLAFWSVDRDHPGPTGEVSPLHRGTNDPDWAFSHVFVKFMEAFGYTFSAQTSEASVPT
>Mature_717_residues
MKYLDFINVMTYDYHGAWDPITGHLAPLYADPNAPYEDPNIKWNFNVNASIQWYLKHGVNPKQLGLGLPFYGRSFANVPP
ENNGLYQPFSGTPAGTWGPAYETHGVMDYWDIEEKRASGQYNYYWDPVAMVPWLYSPSLKIFISYDDKKSIGIKVDYALK
YNLGGVMVWEITADRKPGTNSHPLLDTILEHIAQGGGVVPTPSPTPTPTPTPTPTPTTTTTTSTPTPTTTTTPSPTTTTT
TTTTTTTTSTTTTPTTTTTPVPVSGSLEVKVNDWGSGAEYDVTLNLDGQYDWTVKVKLAPGATVGSFWSANKQEGNGYVI
FTPVSWNKGPTATFGFIVNGPQGDKVEEITLEINGQVIDIWTPTGGTTPTPTTTTTSTPTPSQTPTPTPTPTPTPTPTPT
LTPTPLPGNANPIPEHFFAPYIDMSLSVHKPLVEYAKLTGTKYFTLAFILYSSVYNGPAWAGSIPLEKFVDEVRELREIG
GEVIIAFGGAVGPYLCQQASTPEQLAEWYIKVIDTYNATYLDFDIEAGIDADKLADALLIVQRERPWVKFSFTLPSDPGI
GLAGGYGIIETMAKKGVRVDRVNPMTMDYYWTPSNAENAIKVAENVFRQLKQIYPEKSDEEIWKMIGLTPMIGVNDDKSV
FTLEDAQQLVDWAIQHKIGSLAFWSVDRDHPGPTGEVSPLHRGTNDPDWAFSHVFVKFMEAFGYTFSAQTSEASVPT

Specific function: Bifunctional enzyme with lysozyme/chitinase activity [H]

COG id: COG3325

COG function: function code G; Chitinase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 chitin-binding type-3 domains [H]

Homologues:

Organism=Homo sapiens, GI4502809, Length=226, Percent_Identity=29.2035398230088, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI42542398, Length=206, Percent_Identity=32.0388349514563, Blast_Score=93, Evalue=8e-19,
Organism=Homo sapiens, GI133893286, Length=206, Percent_Identity=32.0388349514563, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI68533255, Length=196, Percent_Identity=30.1020408163265, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI68533253, Length=196, Percent_Identity=30.1020408163265, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI68533260, Length=196, Percent_Identity=30.1020408163265, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI58386720, Length=178, Percent_Identity=31.4606741573034, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI144226251, Length=185, Percent_Identity=31.8918918918919, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI1789736, Length=312, Percent_Identity=31.7307692307692, Blast_Score=151, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17563680, Length=177, Percent_Identity=31.0734463276836, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559362, Length=177, Percent_Identity=31.0734463276836, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17551250, Length=204, Percent_Identity=32.843137254902, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71995504, Length=183, Percent_Identity=31.1475409836066, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17531695, Length=197, Percent_Identity=26.9035532994924, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71993650, Length=183, Percent_Identity=28.4153005464481, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17535567, Length=175, Percent_Identity=31.4285714285714, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17539198, Length=183, Percent_Identity=26.775956284153, Blast_Score=67, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32564156, Length=257, Percent_Identity=24.9027237354086, Blast_Score=66, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320579, Length=186, Percent_Identity=29.0322580645161, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550474, Length=227, Percent_Identity=32.5991189427313, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI221329807, Length=201, Percent_Identity=32.3383084577114, Blast_Score=106, Evalue=7e-23,
Organism=Drosophila melanogaster, GI161077700, Length=201, Percent_Identity=32.3383084577114, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI221330815, Length=194, Percent_Identity=31.9587628865979, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI116007452, Length=321, Percent_Identity=29.595015576324, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655584, Length=244, Percent_Identity=31.1475409836066, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24640248, Length=178, Percent_Identity=34.2696629213483, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI22024049, Length=231, Percent_Identity=30.7359307359307, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21358195, Length=280, Percent_Identity=28.2142857142857, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573679, Length=187, Percent_Identity=32.620320855615, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003610
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF02839 CBM_5_12 [H]

EC number: =3.2.1.14; =3.2.1.17 [H]

Molecular weight: Translated: 78636; Mature: 78636

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLDFINVMTYDYHGAWDPITGHLAPLYADPNAPYEDPNIKWNFNVNASIQWYLKHGVN
CCHHHEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCEEEEEEECCCC
PKQLGLGLPFYGRSFANVPPENNGLYQPFSGTPAGTWGPAYETHGVMDYWDIEEKRASGQ
HHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEECCHHHHCCCC
YNYYWDPVAMVPWLYSPSLKIFISYDDKKSIGIKVDYALKYNLGGVMVWEITADRKPGTN
CCEEECHHHHCCEEECCCEEEEEEECCCCCCEEEEEEEEEECCCCEEEEEEEECCCCCCC
SHPLLDTILEHIAQGGGVVPTPSPTPTPTPTPTPTPTTTTTTSTPTPTTTTTPSPTTTTT
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCEEE
TTTTTTTTSTTTTPTTTTTPVPVSGSLEVKVNDWGSGAEYDVTLNLDGQYDWTVKVKLAP
EEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCEEEEEEEEECC
GATVGSFWSANKQEGNGYVIFTPVSWNKGPTATFGFIVNGPQGDKVEEITLEINGQVIDI
CCCCCHHCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCEEEEEEEECCEEEEE
WTPTGGTTPTPTTTTTSTPTPSQTPTPTPTPTPTPTPTPTLTPTPLPGNANPIPEHFFAP
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
YIDMSLSVHKPLVEYAKLTGTKYFTLAFILYSSVYNGPAWAGSIPLEKFVDEVRELREIG
EECCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCC
GEVIIAFGGAVGPYLCQQASTPEQLAEWYIKVIDTYNATYLDFDIEAGIDADKLADALLI
CEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHCEEEE
VQRERPWVKFSFTLPSDPGIGLAGGYGIIETMAKKGVRVDRVNPMTMDYYWTPSNAENAI
EECCCCEEEEEEECCCCCCCEEECCHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCHHH
KVAENVFRQLKQIYPEKSDEEIWKMIGLTPMIGVNDDKSVFTLEDAQQLVDWAIQHKIGS
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHCCC
LAFWSVDRDHPGPTGEVSPLHRGTNDPDWAFSHVFVKFMEAFGYTFSAQTSEASVPT
EEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCCCCCC
>Mature Secondary Structure
MKYLDFINVMTYDYHGAWDPITGHLAPLYADPNAPYEDPNIKWNFNVNASIQWYLKHGVN
CCHHHEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCEEEEEEECCCC
PKQLGLGLPFYGRSFANVPPENNGLYQPFSGTPAGTWGPAYETHGVMDYWDIEEKRASGQ
HHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEECCHHHHCCCC
YNYYWDPVAMVPWLYSPSLKIFISYDDKKSIGIKVDYALKYNLGGVMVWEITADRKPGTN
CCEEECHHHHCCEEECCCEEEEEEECCCCCCEEEEEEEEEECCCCEEEEEEEECCCCCCC
SHPLLDTILEHIAQGGGVVPTPSPTPTPTPTPTPTPTTTTTTSTPTPTTTTTPSPTTTTT
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCEEE
TTTTTTTTSTTTTPTTTTTPVPVSGSLEVKVNDWGSGAEYDVTLNLDGQYDWTVKVKLAP
EEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCEEEEEEEEECC
GATVGSFWSANKQEGNGYVIFTPVSWNKGPTATFGFIVNGPQGDKVEEITLEINGQVIDI
CCCCCHHCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCEEEEEEEECCEEEEE
WTPTGGTTPTPTTTTTSTPTPSQTPTPTPTPTPTPTPTPTLTPTPLPGNANPIPEHFFAP
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
YIDMSLSVHKPLVEYAKLTGTKYFTLAFILYSSVYNGPAWAGSIPLEKFVDEVRELREIG
EECCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCC
GEVIIAFGGAVGPYLCQQASTPEQLAEWYIKVIDTYNATYLDFDIEAGIDADKLADALLI
CEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHCEEEE
VQRERPWVKFSFTLPSDPGIGLAGGYGIIETMAKKGVRVDRVNPMTMDYYWTPSNAENAI
EECCCCEEEEEEECCCCCCCEEECCHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCHHH
KVAENVFRQLKQIYPEKSDEEIWKMIGLTPMIGVNDDKSVFTLEDAQQLVDWAIQHKIGS
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHCCC
LAFWSVDRDHPGPTGEVSPLHRGTNDPDWAFSHVFVKFMEAFGYTFSAQTSEASVPT
EEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 2661540; 10419961; 10760150 [H]