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The map label for this gene is chiA1 [H]

Identifier: 18977606

GI number: 18977606

Start: 1168805

End: 1169842

Strand: Reverse

Name: chiA1 [H]

Synonym: PF1234

Alternate gene names: 18977606

Gene position: 1169842-1168805 (Counterclockwise)

Preceding gene: 18977611

Following gene: 18977605

Centisome position: 61.3

GC content: 40.94

Gene sequence:

>1038_bases
ATGAAGACTAGAATGCTCGGTATTGTGCTTGCATGGTTGGTTGTGTTGAGTCTAGTGTCTCCCACCATATCTCTATTCTA
TCCAGTATCGGCCCAACAAACAGTGCAGCTAGATGGCTATGCAATCTCATGGGACGTTGTCAATTTAACTTGGACCCCAG
TAGAAAACGTAAATGGATATGAAATTTACAGAAGCACTTCAATGGAAAACCTAGTCTCTCTTCAAAACCTCCTGGTCTAT
GTAAACTGGAGCAGTTATCCAAAGTATGAGCCAGGTAAAGAATATAACCAAGGAGATATCGTTGAATATAACGGCAAACT
TTACAAAGCGAAATACTGGACAACCTCTCCACCAAGCGACGATCCCTATGGATCCTGGGAATATTTGGGTGAGGCAGAGC
CAACTACAAACTACTTGGATCAATTTAGACTAAAACCAGAAACTACGTACTACTATGCAGTAGTCCCAGTATTTAAGGAT
GGATCAAGAGGAGAGCCTTCTAACATAATTAGGATAACCACCCCAAAGGAACCCTTCAGAGTTGTTGTCTACTATATATC
ATGGGGAATTTATGCAAGAAAGTTTTTCCCTGAGGACATTCCATTTGAGAAGGTAACTCATGTGAACTATGCATTCCTCA
ATCCAAAGGAAGATGGAACTGTCGACTTTTATGACACCTGGGCTGATCCTCAGAACCTTGAGAAGTTCAAAGAGTTAAAG
AAGAAGTATCCTCAAGTTAAAATTTTAATTTCAGTAGGAGGATGGACATTAAGTAAGTACTTTTCAGTAATTGCTGCAGA
TCCAGCAAAGAGAGAAAGGTTTGCAAGAACTGCCCTAGAAATAATTAGGAAATACAACTTGGATGGCCTTGACATTGACT
GGGAGTACCCAGGCGGAGGAGGAATGGAAGGAAACTACGTGAGCCCAGACGATGGAAAGAACTTCGTGCTGTTAGTTAAG
ACTGTAAGAGAGATATTTGATCAAGCCGAATTAGAAGATAAAAAAAGAGTATCTCCTAACTGCAGCAGTTCCAGCTGA

Upstream 100 bases:

>100_bases
TTGTATAATTGCAAAAAGGTATAAATTTATATAGATCACCTGCATTATACCACCATGAAATTCCTTATTCCATAGAGAAC
ATTAGATGGGAGGGGAAGTT

Downstream 100 bases:

>100_bases
TCCAGTTAAAGCTGCAAGAATAAATTGGACTGAGGCTATGAAATATCTCGACTTCATCAATGTAATGACATATGATTATC
ATGGAGCCTGGGATCCAATT

Product: putative chitinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKTRMLGIVLAWLVVLSLVSPTISLFYPVSAQQTVQLDGYAISWDVVNLTWTPVENVNGYEIYRSTSMENLVSLQNLLVY
VNWSSYPKYEPGKEYNQGDIVEYNGKLYKAKYWTTSPPSDDPYGSWEYLGEAEPTTNYLDQFRLKPETTYYYAVVPVFKD
GSRGEPSNIIRITTPKEPFRVVVYYISWGIYARKFFPEDIPFEKVTHVNYAFLNPKEDGTVDFYDTWADPQNLEKFKELK
KKYPQVKILISVGGWTLSKYFSVIAADPAKRERFARTALEIIRKYNLDGLDIDWEYPGGGGMEGNYVSPDDGKNFVLLVK
TVREIFDQAELEDKKRVSPNCSSSS

Sequences:

>Translated_345_residues
MKTRMLGIVLAWLVVLSLVSPTISLFYPVSAQQTVQLDGYAISWDVVNLTWTPVENVNGYEIYRSTSMENLVSLQNLLVY
VNWSSYPKYEPGKEYNQGDIVEYNGKLYKAKYWTTSPPSDDPYGSWEYLGEAEPTTNYLDQFRLKPETTYYYAVVPVFKD
GSRGEPSNIIRITTPKEPFRVVVYYISWGIYARKFFPEDIPFEKVTHVNYAFLNPKEDGTVDFYDTWADPQNLEKFKELK
KKYPQVKILISVGGWTLSKYFSVIAADPAKRERFARTALEIIRKYNLDGLDIDWEYPGGGGMEGNYVSPDDGKNFVLLVK
TVREIFDQAELEDKKRVSPNCSSSS
>Mature_345_residues
MKTRMLGIVLAWLVVLSLVSPTISLFYPVSAQQTVQLDGYAISWDVVNLTWTPVENVNGYEIYRSTSMENLVSLQNLLVY
VNWSSYPKYEPGKEYNQGDIVEYNGKLYKAKYWTTSPPSDDPYGSWEYLGEAEPTTNYLDQFRLKPETTYYYAVVPVFKD
GSRGEPSNIIRITTPKEPFRVVVYYISWGIYARKFFPEDIPFEKVTHVNYAFLNPKEDGTVDFYDTWADPQNLEKFKELK
KKYPQVKILISVGGWTLSKYFSVIAADPAKRERFARTALEIIRKYNLDGLDIDWEYPGGGGMEGNYVSPDDGKNFVLLVK
TVREIFDQAELEDKKRVSPNCSSSS

Specific function: Unknown

COG id: COG3325

COG function: function code G; Chitinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 fibronectin type-III domains [H]

Homologues:

Organism=Homo sapiens, GI133893286, Length=164, Percent_Identity=31.7073170731707, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4502809, Length=166, Percent_Identity=33.1325301204819, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI144226251, Length=173, Percent_Identity=28.9017341040462, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71995504, Length=157, Percent_Identity=38.2165605095541, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559362, Length=171, Percent_Identity=37.4269005847953, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17563680, Length=174, Percent_Identity=35.632183908046, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551250, Length=167, Percent_Identity=32.3353293413174, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564165, Length=94, Percent_Identity=34.0425531914894, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17535579, Length=96, Percent_Identity=30.2083333333333, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI22024049, Length=170, Percent_Identity=39.4117647058824, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221330815, Length=164, Percent_Identity=37.8048780487805, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI45550474, Length=154, Percent_Identity=37.012987012987, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21358195, Length=157, Percent_Identity=35.031847133758, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI116007452, Length=179, Percent_Identity=32.9608938547486, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24655584, Length=176, Percent_Identity=33.5227272727273, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573679, Length=156, Percent_Identity=34.6153846153846, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161077700, Length=165, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI221329807, Length=165, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003610
- InterPro:   IPR011583
- InterPro:   IPR008957
- InterPro:   IPR003961
- InterPro:   IPR001223
- InterPro:   IPR001579
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783 [H]

Pfam domain/function: PF02839 CBM_5_12; PF00041 fn3; PF00704 Glyco_hydro_18 [H]

EC number: =3.2.1.14 [H]

Molecular weight: Translated: 39702; Mature: 39702

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS01095 CHITINASE_18

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRMLGIVLAWLVVLSLVSPTISLFYPVSAQQTVQLDGYAISWDVVNLTWTPVENVNGY
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCEEEEEEEEEEEECCCCCCCCE
EIYRSTSMENLVSLQNLLVYVNWSSYPKYEPGKEYNQGDIVEYNGKLYKAKYWTTSPPSD
EEEECCCHHHHHHHEEEEEEEECCCCCCCCCCCCCCCCCEEEECCEEEEEEEECCCCCCC
DPYGSWEYLGEAEPTTNYLDQFRLKPETTYYYAVVPVFKDGSRGEPSNIIRITTPKEPFR
CCCCCHHCCCCCCCCHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCEEEEECCCCCEE
VVVYYISWGIYARKFFPEDIPFEKVTHVNYAFLNPKEDGTVDFYDTWADPQNLEKFKELK
EEEEEEECCHHHHHCCCCCCCHHHEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHH
KKYPQVKILISVGGWTLSKYFSVIAADPAKRERFARTALEIIRKYNLDGLDIDWEYPGGG
HHCCEEEEEEEECCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
GMEGNYVSPDDGKNFVLLVKTVREIFDQAELEDKKRVSPNCSSSS
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MKTRMLGIVLAWLVVLSLVSPTISLFYPVSAQQTVQLDGYAISWDVVNLTWTPVENVNGY
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCEEEEEEEEEEEECCCCCCCCE
EIYRSTSMENLVSLQNLLVYVNWSSYPKYEPGKEYNQGDIVEYNGKLYKAKYWTTSPPSD
EEEECCCHHHHHHHEEEEEEEECCCCCCCCCCCCCCCCCEEEECCEEEEEEEECCCCCCC
DPYGSWEYLGEAEPTTNYLDQFRLKPETTYYYAVVPVFKDGSRGEPSNIIRITTPKEPFR
CCCCCHHCCCCCCCCHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCEEEEECCCCCEE
VVVYYISWGIYARKFFPEDIPFEKVTHVNYAFLNPKEDGTVDFYDTWADPQNLEKFKELK
EEEEEEECCHHHHHCCCCCCCHHHEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHH
KKYPQVKILISVGGWTLSKYFSVIAADPAKRERFARTALEIIRKYNLDGLDIDWEYPGGG
HHCCEEEEEEEECCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
GMEGNYVSPDDGKNFVLLVKTVREIFDQAELEDKKRVSPNCSSSS
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2203782; 8103047 [H]