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The map label for this gene is cutA [H]

Identifier: 18977403

GI number: 18977403

Start: 987709

End: 988020

Strand: Reverse

Name: cutA [H]

Synonym: PF1031

Alternate gene names: 18977403

Gene position: 988020-987709 (Counterclockwise)

Preceding gene: 18977404

Following gene: 18977399

Centisome position: 51.78

GC content: 35.9

Gene sequence:

>312_bases
ATGATAATTATATATACAACTTTTCCTACCTGGGAAAGTGCAGAAAAAGTTACAAAGGCTCTTTTAGAAGAGAGGCTTGT
TGCATGTGCTAATCTGAGAGAACATAAGGCTTTTTACTGGTGGCAAGGTAAGATCGAAGAAGATAACGAGATTGGAGTGA
TTTTAAAGACTAGGGAAGATCTTTGGGAGGAAGTCAAAAAGAGAATAAAAGAGCTCCATCCATACACTGTCCCAGCAATA
ATAAAAATTAATGTAGAGGATGTAAACGAGGAATACTTAAAATGGTTATTGGAGGAAACGAAATCTACCTAA

Upstream 100 bases:

>100_bases
TAAAACCAGGGGTTAATCTAGAAGAAGGACAATTGTATAGGCTCGTTAAAGTTAAGGGGAGATTTTACATAAAGGAAAAG
GAGGGTGAAGAATGAGTAAG

Downstream 100 bases:

>100_bases
CTTTTGCTCCCAGCTTTACTTCCTTATCTGGCATTAACAGTGCAACTTTCTCACCATCATCCGCGGCTAGTAGCATTCCT
TGGCTCTCAACTCCTCTTAG

Product: divalent cation tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 103; Mature: 103

Protein sequence:

>103_residues
MIIIYTTFPTWESAEKVTKALLEERLVACANLREHKAFYWWQGKIEEDNEIGVILKTREDLWEEVKKRIKELHPYTVPAI
IKINVEDVNEEYLKWLLEETKST

Sequences:

>Translated_103_residues
MIIIYTTFPTWESAEKVTKALLEERLVACANLREHKAFYWWQGKIEEDNEIGVILKTREDLWEEVKKRIKELHPYTVPAI
IKINVEDVNEEYLKWLLEETKST
>Mature_103_residues
MIIIYTTFPTWESAEKVTKALLEERLVACANLREHKAFYWWQGKIEEDNEIGVILKTREDLWEEVKKRIKELHPYTVPAI
IKINVEDVNEEYLKWLLEETKST

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526026, Length=99, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=5e-15,
Organism=Homo sapiens, GI62526024, Length=99, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=6e-15,
Organism=Homo sapiens, GI62526022, Length=99, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=6e-15,
Organism=Homo sapiens, GI7706244, Length=99, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=6e-15,
Organism=Homo sapiens, GI62198241, Length=99, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790579, Length=96, Percent_Identity=31.25, Blast_Score=64, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32565476, Length=104, Percent_Identity=38.4615384615385, Blast_Score=82, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641937, Length=97, Percent_Identity=34.020618556701, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 12336; Mature: 12336

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIIYTTFPTWESAEKVTKALLEERLVACANLREHKAFYWWQGKIEEDNEIGVILKTRED
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHCCEEEEEECEECCCCCEEEEEECHHH
LWEEVKKRIKELHPYTVPAIIKINVEDVNEEYLKWLLEETKST
HHHHHHHHHHHCCCCCCCEEEEEEHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIIYTTFPTWESAEKVTKALLEERLVACANLREHKAFYWWQGKIEEDNEIGVILKTRED
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHCCEEEEEECEECCCCCEEEEEECHHH
LWEEVKKRIKELHPYTVPAIIKINVEDVNEEYLKWLLEETKST
HHHHHHHHHHHCCCCCCCEEEEEEHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]