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The map label for this gene is yisS [H]

Identifier: 18977138

GI number: 18977138

Start: 758735

End: 759685

Strand: Reverse

Name: yisS [H]

Synonym: PF0766

Alternate gene names: 18977138

Gene position: 759685-758735 (Counterclockwise)

Preceding gene: 18977139

Following gene: 18977137

Centisome position: 39.81

GC content: 47.21

Gene sequence:

>951_bases
ATGCTCAGGGTGGGCGTTGTAGGCGTTGGAAACATGGGGTTTCATCACGCAAGGGTCTACTCTGAATTGGCCAGAGAGGG
GAAAGTAGAGCTCGTGGGAGTTGCTGATGTGAACTTTGAAAGGGCTAGAGAGGTTGCAAAGAAGTTCAACACAATCCCGT
ACGCTGACTACAAGGAGCTCGCAAAGGAGGATCTAGATGCCGTTAGTATAGCGGTTCCAACGTCCCTCCACAAGCAGGTG
GCCATAGAATTCATGGAGAGGGGAATAAACGTCCTGGTAGAGAAGCCGATAGCTGAGAGCATCGAGAGCGCTAGGGAAAT
GATTAGGGTAGCAAAAGAGAATAAAGTTATTCTAATGGTTGGCCACATAGAGAGGTTCAATCCAGCCGTCATCAAGCTCA
AGGAGAGCATAGAGAAGGGCCTCCTAGGAGAAGTTATCTCCATTAGTGCTAAGAGAGTGGGCCCAATGGCAATTAGGATC
AGGGATGTTGGGATAATAATAGATTTGGGGGTTCACGATATAGATGTAATAAGTTACCTCTTCAATGATAGGGTTAGGAA
GGTATACGCCAGGGCTGGAAACGTGAAGCATCCTGCTGGAGTGGAAGATCACGCGCTCATAATGCTCGGTTTTTCAAACG
GAAAGAGTGGGATAATAGAGACGAACTGGTTAACTCCACATAAGACGAGAACGTTGACGGCCGTTGGAACGGAGGGGATA
GCGTACCTAGACTACATCCAGCAGAAGCTCGTAATATACAACGATGAATGGGAGAAAATAGCGAAGATCGAGAGAAGGGA
ACCCTTAAAGAACGAGATCGAGCACTTCATAGAGTGCATCAAGGAAAACAAGGAACCCTTGATATCTGGTGAAGATGGAT
TGCACGTTCTTAAGGTTGCCCTGAAGGCTTTGGAGAGCTCAAAAAGAGATGAGGTCTTGGAGGTGGAATAA

Upstream 100 bases:

>100_bases
AGGCCAGCAAGAGAGTTCTAAGCTTGCCAGTGCATCCAGCTGTCAGTAAGGAGGACATAAATTACATAATTAGGACGCTT
GAAGAGCTTGGGTGATCCTA

Downstream 100 bases:

>100_bases
TTGAAGCTCCTGGGATTAAGTAGGGAAGAGGTTAAACAGGCCTTAAGGGATGGGAAGGTGACGATAGCGGTTTATGGACT
AGGTAAGATGGGGCTTCCCC

Product: putative dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLRVGVVGVGNMGFHHARVYSELAREGKVELVGVADVNFERAREVAKKFNTIPYADYKELAKEDLDAVSIAVPTSLHKQV
AIEFMERGINVLVEKPIAESIESAREMIRVAKENKVILMVGHIERFNPAVIKLKESIEKGLLGEVISISAKRVGPMAIRI
RDVGIIIDLGVHDIDVISYLFNDRVRKVYARAGNVKHPAGVEDHALIMLGFSNGKSGIIETNWLTPHKTRTLTAVGTEGI
AYLDYIQQKLVIYNDEWEKIAKIERREPLKNEIEHFIECIKENKEPLISGEDGLHVLKVALKALESSKRDEVLEVE

Sequences:

>Translated_316_residues
MLRVGVVGVGNMGFHHARVYSELAREGKVELVGVADVNFERAREVAKKFNTIPYADYKELAKEDLDAVSIAVPTSLHKQV
AIEFMERGINVLVEKPIAESIESAREMIRVAKENKVILMVGHIERFNPAVIKLKESIEKGLLGEVISISAKRVGPMAIRI
RDVGIIIDLGVHDIDVISYLFNDRVRKVYARAGNVKHPAGVEDHALIMLGFSNGKSGIIETNWLTPHKTRTLTAVGTEGI
AYLDYIQQKLVIYNDEWEKIAKIERREPLKNEIEHFIECIKENKEPLISGEDGLHVLKVALKALESSKRDEVLEVE
>Mature_316_residues
MLRVGVVGVGNMGFHHARVYSELAREGKVELVGVADVNFERAREVAKKFNTIPYADYKELAKEDLDAVSIAVPTSLHKQV
AIEFMERGINVLVEKPIAESIESAREMIRVAKENKVILMVGHIERFNPAVIKLKESIEKGLLGEVISISAKRVGPMAIRI
RDVGIIIDLGVHDIDVISYLFNDRVRKVYARAGNVKHPAGVEDHALIMLGFSNGKSGIIETNWLTPHKTRTLTAVGTEGI
AYLDYIQQKLVIYNDEWEKIAKIERREPLKNEIEHFIECIKENKEPLISGEDGLHVLKVALKALESSKRDEVLEVE

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=302, Percent_Identity=25.8278145695364, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87082405, Length=240, Percent_Identity=30, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787574, Length=192, Percent_Identity=27.6041666666667, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787307, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581117, Length=226, Percent_Identity=29.646017699115, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24581115, Length=151, Percent_Identity=29.1390728476821, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35433; Mature: 35433

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRVGVVGVGNMGFHHARVYSELAREGKVELVGVADVNFERAREVAKKFNTIPYADYKEL
CEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHH
AKEDLDAVSIAVPTSLHKQVAIEFMERGINVLVEKPIAESIESAREMIRVAKENKVILMV
HHHCCCCEEEECCHHHHHHHHHHHHHCCHHEEECCHHHHHHHHHHHHHHHHCCCCEEEEE
GHIERFNPAVIKLKESIEKGLLGEVISISAKRVGPMAIRIRDVGIIIDLGVHDIDVISYL
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCHHHHHHHH
FNDRVRKVYARAGNVKHPAGVEDHALIMLGFSNGKSGIIETNWLTPHKTRTLTAVGTEGI
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCEEEEEECCCCH
AYLDYIQQKLVIYNDEWEKIAKIERREPLKNEIEHFIECIKENKEPLISGEDGLHVLKVA
HHHHHHHHHHEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LKALESSKRDEVLEVE
HHHHHCCCCCCCEECC
>Mature Secondary Structure
MLRVGVVGVGNMGFHHARVYSELAREGKVELVGVADVNFERAREVAKKFNTIPYADYKEL
CEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHH
AKEDLDAVSIAVPTSLHKQVAIEFMERGINVLVEKPIAESIESAREMIRVAKENKVILMV
HHHCCCCEEEECCHHHHHHHHHHHHHCCHHEEECCHHHHHHHHHHHHHHHHCCCCEEEEE
GHIERFNPAVIKLKESIEKGLLGEVISISAKRVGPMAIRIRDVGIIIDLGVHDIDVISYL
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCHHHHHHHH
FNDRVRKVYARAGNVKHPAGVEDHALIMLGFSNGKSGIIETNWLTPHKTRTLTAVGTEGI
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCEEEEEECCCCH
AYLDYIQQKLVIYNDEWEKIAKIERREPLKNEIEHFIECIKENKEPLISGEDGLHVLKVA
HHHHHHHHHHEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LKALESSKRDEVLEVE
HHHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377; 8407808 [H]