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The map label for this gene is pilQ [H]

Identifier: 189424531

GI number: 189424531

Start: 1534288

End: 1536666

Strand: Reverse

Name: pilQ [H]

Synonym: Glov_1469

Alternate gene names: 189424531

Gene position: 1536666-1534288 (Counterclockwise)

Preceding gene: 189424532

Following gene: 189424530

Centisome position: 39.22

GC content: 58.68

Gene sequence:

>2379_bases
ATGATGCCTACAATACAGCACGCGCTCCGGCTCCTGAGCGGGATACTGCTTGCGGCTGCACTCTGCCTGCCGGGCTGTTC
CGCAGCCCAAAAGGCGTTTAGCAAAGGAGAAGAGCTGGAGCAGGAAGGCAACTTTGAGGCTGCCATGTATCGCTACGCCG
AGGCCTTCAGCAAAAATGCTGCGGAGAGCAGCTACCGCCTCAGCTTTTTCAGGGCCCGTGAGGCAGCAGCCAAACAACGC
TTCAAGGCCGGTACCGAGCTGATGTCCAAAGCGCTGTATGCCGCTGCTGAGGAACAGTTTCAGACGGCAGCGAGTCTTGA
CCCGACCCAGGAACGGTTCAGACAGCTGGCTGACCAGGCCGCACGCCTCAACCAGGCAGACAAAATCTATCGCGAAGGGC
TTGATTTTGAAAAGGCCAACAAGCCGCAGTATGCCCGCAGTGCCTTTCAACAGGCTTTTGAGCTCCGGCCCGATGCCAAA
CTGTATCAGGAAGCGTTGCAACGGGTAGCAGGCAGCCCCGCGACCAGTCTGGCCGGTCGGGATCTGCAGCTTACATCGGT
GAAGCCGTTGACGCTGAAGGCCAACGGCACCAGACTGAAAGAGTTATTCAGCACCATCACCCGGCATTCCGGCATCAACT
TTGTCTTTGATCCTGACTTCAAGGATCAACCCGCAACCCTCACCCTGGAAAACAGCGGTTTCCGCCAGGCACTCGATCTG
CTGGCCGCCCTGCACAGGATTGACTATGCCGTTATCAACGAGAGCACGGTATTGATCTACCCGCAGAGTGCGGAGAAGAC
CAAGCAGTACCAGGACATGCAGCTGCGCACCTTCCACCTGAACCACCTGGATGCCAAGAAGGCGGCCAACCTGATCAGGA
CCATGCTGCAGGTCAGGCGGCTGTATATCAACGAGGATGCCAATGCCCTGGTGGTACGGGATACCAGTGATGTCACCGAT
GTGATCGAAAAGATCCTGGAGGCCCATGACCTGCCGGAGGCAGAGGTGGTGCTGGATGTCGAGGTGATCGAGATCAGTGA
CAAGAACGCCCACAACGTCGGTCTGCTGCTGAGCAACTACGATGTGCAGCTGGGGGCGTTCTCCCCCAGCAACGAACTGC
TGGCAACCACGCTCAAGGACACCACCTCCACGACATCCACCACGGTCACCACCGATGCCACCATCAAGAACCTGGTCAAG
GCCTTCAGCATCAACAGCTTCGGCGGTTATGTCACCGTGCCCAATGCCCAGTACAACTTCGGCAAGACCCTGGCCAACGG
CGAGGTACTCTCCAATCCCAAGATCAGGGTCAAGAACAAGGAAAAGGCCAAGTTCAATGTCGGCACCAGGGTACCGATCA
CCACCACCACCATGGCCACCACCGGCACCACCTCGCAGGTCAACGTGCAGTACGTGGATGTGGGGGTCAAGGTCAATGCC
GAGCCCACCATCCAGCTCAACAACGAGGTTTCCATCAAGCTGGGACTTGAGGTCAGCTCGATCATCTCCCGCGAGACCGT
GGGGGGCAAGGACAGTGCCACCACGGTGGTCACCATTGGCACCCGCAACCTGGATACGGTCCTAAGCCTCAAAGACGGTG
AGACCAGTGTCATCGGCGGTCTGATCTCCCACAGCAACAGCGACAGCAAACAGAAGATCTTCCTGCTGGGTGACATCCCG
CTGATCGGACCGCTCTTGTCAAACAGCAAGACCGACAACGACAAGACCGAGCTGATCCTGGCCATTACACCCAGGCTCGT
CAGGGGCGTGACCGTCCCCCGAGGCAACCTGACATCCTTCTCAAGCAGTAAGGAGGACCGCCCTGCAGTGCAGCCGCTGC
CCGCAATTCAACCGTCAGCCCCACCTGCGGTTCCGGCTGCCGCCAGACCGGCAGTTCCGGTTGTTTCCCCGGCAGCCCCT
TCAGTACCCCCGCCCGTCAGCAGTGCTCCCGTTGCTCCTGCTGCCATCCCGAATACCCTCACCATCAATGCTCCCAGTTC
AACTGTACCCGGTCAGTCATTCAAGGTGCTGGTCAGCGCAGAAGGGGTATCCGATATGAAGGGCGGCAGTTTCTCACTGA
ACTACACACCGGCACTACTGGAACTGCTCTCAACCGCACAAGGGACGCTACTCGGCAAGGATAACGGCCCGGACGCCTTT
ACCACCACGGACGACCCGGTCAAAGGCAATGTCACCGTCACCCTGCAACAAGCCGATACCGCAACCGGGGCCACCGGCAG
CGGTACGCTGGCCGGTTTTATCTTCAGGTCCAAAGGCAAAGGCACCGCCAATCTCACCATCGGCCAGACACGTATCCTGT
CAGCCACAGGGCAATTCCTCCCCCTGAAAGCCACCTCCAAGAGCATTACCATCCAGTAA

Upstream 100 bases:

>100_bases
GCCTTATATCCGGCCTTCCTCATAACGTTCTTAAAAGCCCTGTTCATCTTTCGCTTGTTACTTGGCAACCGGAAACGCTA
TAGATAGCCCCATGCCCAGA

Downstream 100 bases:

>100_bases
CACGGCATGCAACGTTGCACATGCAACTTTTTCTTGACAAGTTTGATACGCGTATCTTAGTGTAAAGATAAGATTGTCAG
TAAACAGACCACAACTGAAT

Product: type II and III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 792; Mature: 792

Protein sequence:

>792_residues
MMPTIQHALRLLSGILLAAALCLPGCSAAQKAFSKGEELEQEGNFEAAMYRYAEAFSKNAAESSYRLSFFRAREAAAKQR
FKAGTELMSKALYAAAEEQFQTAASLDPTQERFRQLADQAARLNQADKIYREGLDFEKANKPQYARSAFQQAFELRPDAK
LYQEALQRVAGSPATSLAGRDLQLTSVKPLTLKANGTRLKELFSTITRHSGINFVFDPDFKDQPATLTLENSGFRQALDL
LAALHRIDYAVINESTVLIYPQSAEKTKQYQDMQLRTFHLNHLDAKKAANLIRTMLQVRRLYINEDANALVVRDTSDVTD
VIEKILEAHDLPEAEVVLDVEVIEISDKNAHNVGLLLSNYDVQLGAFSPSNELLATTLKDTTSTTSTTVTTDATIKNLVK
AFSINSFGGYVTVPNAQYNFGKTLANGEVLSNPKIRVKNKEKAKFNVGTRVPITTTTMATTGTTSQVNVQYVDVGVKVNA
EPTIQLNNEVSIKLGLEVSSIISRETVGGKDSATTVVTIGTRNLDTVLSLKDGETSVIGGLISHSNSDSKQKIFLLGDIP
LIGPLLSNSKTDNDKTELILAITPRLVRGVTVPRGNLTSFSSSKEDRPAVQPLPAIQPSAPPAVPAAARPAVPVVSPAAP
SVPPPVSSAPVAPAAIPNTLTINAPSSTVPGQSFKVLVSAEGVSDMKGGSFSLNYTPALLELLSTAQGTLLGKDNGPDAF
TTTDDPVKGNVTVTLQQADTATGATGSGTLAGFIFRSKGKGTANLTIGQTRILSATGQFLPLKATSKSITIQ

Sequences:

>Translated_792_residues
MMPTIQHALRLLSGILLAAALCLPGCSAAQKAFSKGEELEQEGNFEAAMYRYAEAFSKNAAESSYRLSFFRAREAAAKQR
FKAGTELMSKALYAAAEEQFQTAASLDPTQERFRQLADQAARLNQADKIYREGLDFEKANKPQYARSAFQQAFELRPDAK
LYQEALQRVAGSPATSLAGRDLQLTSVKPLTLKANGTRLKELFSTITRHSGINFVFDPDFKDQPATLTLENSGFRQALDL
LAALHRIDYAVINESTVLIYPQSAEKTKQYQDMQLRTFHLNHLDAKKAANLIRTMLQVRRLYINEDANALVVRDTSDVTD
VIEKILEAHDLPEAEVVLDVEVIEISDKNAHNVGLLLSNYDVQLGAFSPSNELLATTLKDTTSTTSTTVTTDATIKNLVK
AFSINSFGGYVTVPNAQYNFGKTLANGEVLSNPKIRVKNKEKAKFNVGTRVPITTTTMATTGTTSQVNVQYVDVGVKVNA
EPTIQLNNEVSIKLGLEVSSIISRETVGGKDSATTVVTIGTRNLDTVLSLKDGETSVIGGLISHSNSDSKQKIFLLGDIP
LIGPLLSNSKTDNDKTELILAITPRLVRGVTVPRGNLTSFSSSKEDRPAVQPLPAIQPSAPPAVPAAARPAVPVVSPAAP
SVPPPVSSAPVAPAAIPNTLTINAPSSTVPGQSFKVLVSAEGVSDMKGGSFSLNYTPALLELLSTAQGTLLGKDNGPDAF
TTTDDPVKGNVTVTLQQADTATGATGSGTLAGFIFRSKGKGTANLTIGQTRILSATGQFLPLKATSKSITIQ
>Mature_792_residues
MMPTIQHALRLLSGILLAAALCLPGCSAAQKAFSKGEELEQEGNFEAAMYRYAEAFSKNAAESSYRLSFFRAREAAAKQR
FKAGTELMSKALYAAAEEQFQTAASLDPTQERFRQLADQAARLNQADKIYREGLDFEKANKPQYARSAFQQAFELRPDAK
LYQEALQRVAGSPATSLAGRDLQLTSVKPLTLKANGTRLKELFSTITRHSGINFVFDPDFKDQPATLTLENSGFRQALDL
LAALHRIDYAVINESTVLIYPQSAEKTKQYQDMQLRTFHLNHLDAKKAANLIRTMLQVRRLYINEDANALVVRDTSDVTD
VIEKILEAHDLPEAEVVLDVEVIEISDKNAHNVGLLLSNYDVQLGAFSPSNELLATTLKDTTSTTSTTVTTDATIKNLVK
AFSINSFGGYVTVPNAQYNFGKTLANGEVLSNPKIRVKNKEKAKFNVGTRVPITTTTMATTGTTSQVNVQYVDVGVKVNA
EPTIQLNNEVSIKLGLEVSSIISRETVGGKDSATTVVTIGTRNLDTVLSLKDGETSVIGGLISHSNSDSKQKIFLLGDIP
LIGPLLSNSKTDNDKTELILAITPRLVRGVTVPRGNLTSFSSSKEDRPAVQPLPAIQPSAPPAVPAAARPAVPVVSPAAP
SVPPPVSSAPVAPAAIPNTLTINAPSSTVPGQSFKVLVSAEGVSDMKGGSFSLNYTPALLELLSTAQGTLLGKDNGPDAF
TTTDDPVKGNVTVTLQQADTATGATGSGTLAGFIFRSKGKGTANLTIGQTRILSATGQFLPLKATSKSITIQ

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=417, Percent_Identity=21.3429256594724, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082242, Length=311, Percent_Identity=26.3665594855305, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 84828; Mature: 84828

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS50005 TPR L=RR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPTIQHALRLLSGILLAAALCLPGCSAAQKAFSKGEELEQEGNFEAAMYRYAEAFSKNA
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCC
AESSYRLSFFRAREAAAKQRFKAGTELMSKALYAAAEEQFQTAASLDPTQERFRQLADQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ARLNQADKIYREGLDFEKANKPQYARSAFQQAFELRPDAKLYQEALQRVAGSPATSLAGR
HHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHCCC
DLQLTSVKPLTLKANGTRLKELFSTITRHSGINFVFDPDFKDQPATLTLENSGFRQALDL
CEEEEECCEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEECCCCHHHHHHH
LAALHRIDYAVINESTVLIYPQSAEKTKQYQDMQLRTFHLNHLDAKKAANLIRTMLQVRR
HHHHHHCCEEEECCCEEEEECCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHH
LYINEDANALVVRDTSDVTDVIEKILEAHDLPEAEVVLDVEVIEISDKNAHNVGLLLSNY
HHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCEEEEEEECC
DVQLGAFSPSNELLATTLKDTTSTTSTTVTTDATIKNLVKAFSINSFGGYVTVPNAQYNF
EEEEECCCCCCCEEEEEECCCCCCCCEEEECHHHHHHHHHHHCCCCCCCEEEECCCCCCC
GKTLANGEVLSNPKIRVKNKEKAKFNVGTRVPITTTTMATTGTTSQVNVQYVDVGVKVNA
CCEECCCCEECCCCEEECCCCCCEEECCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECC
EPTIQLNNEVSIKLGLEVSSIISRETVGGKDSATTVVTIGTRNLDTVLSLKDGETSVIGG
CCEEEECCEEEEEECCCHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHH
LISHSNSDSKQKIFLLGDIPLIGPLLSNSKTDNDKTELILAITPRLVRGVTVPRGNLTSF
HHHCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCCC
SSSKEDRPAVQPLPAIQPSAPPAVPAAARPAVPVVSPAAPSVPPPVSSAPVAPAAIPNTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEE
TINAPSSTVPGQSFKVLVSAEGVSDMKGGSFSLNYTPALLELLSTAQGTLLGKDNGPDAF
EEECCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHCCCEEEECCCCCCCC
TTTDDPVKGNVTVTLQQADTATGATGSGTLAGFIFRSKGKGTANLTIGQTRILSATGQFL
CCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEECCEEEEECCCCEE
PLKATSKSITIQ
EEEECCCCEEEC
>Mature Secondary Structure
MMPTIQHALRLLSGILLAAALCLPGCSAAQKAFSKGEELEQEGNFEAAMYRYAEAFSKNA
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCC
AESSYRLSFFRAREAAAKQRFKAGTELMSKALYAAAEEQFQTAASLDPTQERFRQLADQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ARLNQADKIYREGLDFEKANKPQYARSAFQQAFELRPDAKLYQEALQRVAGSPATSLAGR
HHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHCCC
DLQLTSVKPLTLKANGTRLKELFSTITRHSGINFVFDPDFKDQPATLTLENSGFRQALDL
CEEEEECCEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEECCCCHHHHHHH
LAALHRIDYAVINESTVLIYPQSAEKTKQYQDMQLRTFHLNHLDAKKAANLIRTMLQVRR
HHHHHHCCEEEECCCEEEEECCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHH
LYINEDANALVVRDTSDVTDVIEKILEAHDLPEAEVVLDVEVIEISDKNAHNVGLLLSNY
HHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCEEEEEEECC
DVQLGAFSPSNELLATTLKDTTSTTSTTVTTDATIKNLVKAFSINSFGGYVTVPNAQYNF
EEEEECCCCCCCEEEEEECCCCCCCCEEEECHHHHHHHHHHHCCCCCCCEEEECCCCCCC
GKTLANGEVLSNPKIRVKNKEKAKFNVGTRVPITTTTMATTGTTSQVNVQYVDVGVKVNA
CCEECCCCEECCCCEEECCCCCCEEECCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECC
EPTIQLNNEVSIKLGLEVSSIISRETVGGKDSATTVVTIGTRNLDTVLSLKDGETSVIGG
CCEEEECCEEEEEECCCHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHH
LISHSNSDSKQKIFLLGDIPLIGPLLSNSKTDNDKTELILAITPRLVRGVTVPRGNLTSF
HHHCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCCC
SSSKEDRPAVQPLPAIQPSAPPAVPAAARPAVPVVSPAAPSVPPPVSSAPVAPAAIPNTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEE
TINAPSSTVPGQSFKVLVSAEGVSDMKGGSFSLNYTPALLELLSTAQGTLLGKDNGPDAF
EEECCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHCCCEEEECCCCCCCC
TTTDDPVKGNVTVTLQQADTATGATGSGTLAGFIFRSKGKGTANLTIGQTRILSATGQFL
CCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEECCEEEEECCCCEE
PLKATSKSITIQ
EEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]