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The map label for this gene is accD [H]

Identifier: 189424302

GI number: 189424302

Start: 1284753

End: 1285601

Strand: Reverse

Name: accD [H]

Synonym: Glov_1237

Alternate gene names: 189424302

Gene position: 1285601-1284753 (Counterclockwise)

Preceding gene: 189424303

Following gene: 189424301

Centisome position: 32.81

GC content: 57.36

Gene sequence:

>849_bases
ATGAGCTGGTTCAAGCGTGACAAGACAGGGATAGAAAAAAGCAGCACCAAACATGTCAAGGTGCCGGAAGGGCTCTGGAC
AAAGTGCCCGGGCTGCAGCGAATCCCTGCTCACCAAGGAGATTGAGGACAACCTGCAGGTCTGCCCCAAATGCGGGCACC
ACTTCAGAATCGCCACCCGCAAGCGGCTGCAGGCGTTGCTGGACAACGGCAGCTGGCAGGAATTCGATGCAGAAATGACT
TCGATCGACTTCCTGAACTTCAAAGACACCAAGAGCTATCAGGAACGGATCAATGCCACGGTTGCCAAGGGCGGTTCCCG
CGATGCCGTAATCTGTGTCGAAGGCAGCATTGAAGGTATTGCCACCCAGGTTGCCATCTTTGATTTTGCCTTTATGGGTG
GCAGTATGGGCAGTGTGGTGGGAGAAAAAATCACCCGCTCTATCGAGCGAGGCCTTGAAAAAAAACAACCGGTAATCGTG
ATCTCCGCCTCCGGCGGGGCCCGGATGCAGGAGTCAATCCTGTCGCTGATGCAAATGGCCAAGACCTCTGCCGCCCTGGC
CAAGCTGAAGGCCGCCGGCCTGCCGTTCATCTCGATCCTGACCGATCCCACCACCGGCGGCGTCACCGCCAGCTTTGCCA
TGCTGGGCGATCTGAACATTGCCGAGCCCAAGGCATTAATCGGTTTTGCCGGACCGCGGGTCATTGAGCAGACCATTCGC
CAGAAGCTGCCGGCCGGATTCCAGCGTTCCGAGTACCTGCTTGACCACGGCATGGTTGACATGATTGTCTCACGGCTTGA
GATGCGCAGCACCCTGGGCCAGATTCTGGCCATGCTCACCAAGCAGTAG

Upstream 100 bases:

>100_bases
ACAGTACCAGGGAGAGCCGTTGCAAACCGAAGTAACCGGATTGATCAGATCATTAAAACGTGCCATTACGCCGTAAGATT
TTTTCCCGAGAGGATATTCC

Downstream 100 bases:

>100_bases
GCGTGCCCGCTTCACAGCAGCTTTCCCGGCTTTTTGGCCGGCGACGTTTCAACATCAAGCCGGGACTTGAACGGATCACG
GCCCTGCTGGAGCGCCACGG

Product: acetyl-CoA carboxylase, carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSWFKRDKTGIEKSSTKHVKVPEGLWTKCPGCSESLLTKEIEDNLQVCPKCGHHFRIATRKRLQALLDNGSWQEFDAEMT
SIDFLNFKDTKSYQERINATVAKGGSRDAVICVEGSIEGIATQVAIFDFAFMGGSMGSVVGEKITRSIERGLEKKQPVIV
ISASGGARMQESILSLMQMAKTSAALAKLKAAGLPFISILTDPTTGGVTASFAMLGDLNIAEPKALIGFAGPRVIEQTIR
QKLPAGFQRSEYLLDHGMVDMIVSRLEMRSTLGQILAMLTKQ

Sequences:

>Translated_282_residues
MSWFKRDKTGIEKSSTKHVKVPEGLWTKCPGCSESLLTKEIEDNLQVCPKCGHHFRIATRKRLQALLDNGSWQEFDAEMT
SIDFLNFKDTKSYQERINATVAKGGSRDAVICVEGSIEGIATQVAIFDFAFMGGSMGSVVGEKITRSIERGLEKKQPVIV
ISASGGARMQESILSLMQMAKTSAALAKLKAAGLPFISILTDPTTGGVTASFAMLGDLNIAEPKALIGFAGPRVIEQTIR
QKLPAGFQRSEYLLDHGMVDMIVSRLEMRSTLGQILAMLTKQ
>Mature_281_residues
SWFKRDKTGIEKSSTKHVKVPEGLWTKCPGCSESLLTKEIEDNLQVCPKCGHHFRIATRKRLQALLDNGSWQEFDAEMTS
IDFLNFKDTKSYQERINATVAKGGSRDAVICVEGSIEGIATQVAIFDFAFMGGSMGSVVGEKITRSIERGLEKKQPVIVI
SASGGARMQESILSLMQMAKTSAALAKLKAAGLPFISILTDPTTGGVTASFAMLGDLNIAEPKALIGFAGPRVIEQTIRQ
KLPAGFQRSEYLLDHGMVDMIVSRLEMRSTLGQILAMLTKQ

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788655, Length=279, Percent_Identity=58.0645161290323, Blast_Score=348, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI25147362, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25147359, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 30762; Mature: 30631

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWFKRDKTGIEKSSTKHVKVPEGLWTKCPGCSESLLTKEIEDNLQVCPKCGHHFRIATR
CCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHH
KRLQALLDNGSWQEFDAEMTSIDFLNFKDTKSYQERINATVAKGGSRDAVICVEGSIEGI
HHHHHHHCCCCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHH
ATQVAIFDFAFMGGSMGSVVGEKITRSIERGLEKKQPVIVISASGGARMQESILSLMQMA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
KTSAALAKLKAAGLPFISILTDPTTGGVTASFAMLGDLNIAEPKALIGFAGPRVIEQTIR
HHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHH
QKLPAGFQRSEYLLDHGMVDMIVSRLEMRSTLGQILAMLTKQ
HHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SWFKRDKTGIEKSSTKHVKVPEGLWTKCPGCSESLLTKEIEDNLQVCPKCGHHFRIATR
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHH
KRLQALLDNGSWQEFDAEMTSIDFLNFKDTKSYQERINATVAKGGSRDAVICVEGSIEGI
HHHHHHHCCCCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHH
ATQVAIFDFAFMGGSMGSVVGEKITRSIERGLEKKQPVIVISASGGARMQESILSLMQMA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
KTSAALAKLKAAGLPFISILTDPTTGGVTASFAMLGDLNIAEPKALIGFAGPRVIEQTIR
HHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHH
QKLPAGFQRSEYLLDHGMVDMIVSRLEMRSTLGQILAMLTKQ
HHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA