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The map label for this gene is dnaK [H]

Identifier: 189424145

GI number: 189424145

Start: 1125934

End: 1127211

Strand: Reverse

Name: dnaK [H]

Synonym: Glov_1079

Alternate gene names: 189424145

Gene position: 1127211-1125934 (Counterclockwise)

Preceding gene: 189424146

Following gene: 189424144

Centisome position: 28.77

GC content: 56.81

Gene sequence:

>1278_bases
ATGCAACCCGTATTCGGTATCGATTTTGGTACCACCAATTCAGCACTGTCGATCTATCACAACGGCACGGTCGAGGTGGT
GGCCGTTGACGGCACGGACCGTTCCGGAGAGCTGATGCGCTCAGTGCTCTATTTTAACGAAGACAACGAGATCTTTGCCG
GAAATGAAGCGGTCCGCCAGTACGTCGGTGATGGCGCTGCAGGACGTTTTATGCAGTCGATCAAGACATTTTTACCCAAT
ACCAGCTTCGACAGCACCGAGATTTTTGGAAAGCGCTACGCTATCGATGACCTGGTGGCCATCATCCTGAGGCAGATCAA
GGCACGGGGAGAGACGCATCTGGGCTGCCCTGTGGAGCGTGTGGTGCTGGGGCGGCCGGTTCTGTTTTCAACCGATCCTG
CCAAAGACGCCGTGGCTGAGCAGCGTCTGGAAAAGGCTGCCCGCAAGGCAGGTTTTAAACAGATCCGGTTTCAGTATGAA
CCGGTGGCAGCGGCGCTGGCCTTTGAAGAGACATTGCAGCCCGGACAGGAACGGATCGTGTTTATCGGTGATTTCGGCGG
GGGGACTTCGGATTTCTCGGTAATACGCGTTAAAGGGGGCGCCTTTGCCCGCTCCGACCGCCGCAGTGACGTGCTCTCAC
TGGGGGGCGTTTATGTGGCCGGAGACAAGTTCGACTCGCAGATCATGTGGGACAAGGTGGCCCACTATTTTGGCCGCACT
GCCCGCTATAAGACCCTGGGCAAGGATGACTGGGTCACGGTGCCCCGCAGCATCATCTACACCCTCTGCCAGTGGCATCG
CATCCCGCTTTTACGGGCCCGGAAGACCAGAGAGCATATCCGCGTGATCAAAGGCAGTACCGACAATCGCCAGGCGATTC
AGCACCTGGAAAACATCATTGATGACAACTTCGGCTACTTCCTGTTTCAGGCCATAGAAAGCGCCAAGTGCCGGCTTTCC
GACCAGGAACAGGCCAGGATCAGCTTTACGGAGCGGGATCTATGCATCAGCGAGCAGCTCAGCAAGCTGGAGTTCGAGAG
CATCAACCGTGAAAATTTCCGGCAGATTGCCGACTGCATCGATGACGTGCTGGCACGATCCGGTCTGCTACCGGACCGGA
TCGATTCGGTCTTTCTCACCGGAGGCACCTCCCGTATCCCCCATATCCAGGCCCTGTTTGCCGAGCGGTTTGGTAGAGAA
AAACTACATACCAGACAGGCCTTTACCAGCGTTGTCCATGGGCTTGGCGCCAGCGTCCCCCTGTTTACCTGGAGCTGA

Upstream 100 bases:

>100_bases
GGGCCACTTTTCATTCGGGAAAGGGGCCTTCTTTTCTTGCAACCTTAGATCGTGCGATGCCCCGCCAGGCTGCACGCATT
TCCCCGGAGGTATTCAGTAG

Downstream 100 bases:

>100_bases
CCCGGCGGCGTCAGCCTGTGCTCTGTTCTCACCGCTTGACCTGCCGGACGTTGAACTATATGTATAGCTGACTCGCTCAA
ACCAAACCTGTCCCAAGGAG

Product: molecular chaperone-like protein

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MQPVFGIDFGTTNSALSIYHNGTVEVVAVDGTDRSGELMRSVLYFNEDNEIFAGNEAVRQYVGDGAAGRFMQSIKTFLPN
TSFDSTEIFGKRYAIDDLVAIILRQIKARGETHLGCPVERVVLGRPVLFSTDPAKDAVAEQRLEKAARKAGFKQIRFQYE
PVAAALAFEETLQPGQERIVFIGDFGGGTSDFSVIRVKGGAFARSDRRSDVLSLGGVYVAGDKFDSQIMWDKVAHYFGRT
ARYKTLGKDDWVTVPRSIIYTLCQWHRIPLLRARKTREHIRVIKGSTDNRQAIQHLENIIDDNFGYFLFQAIESAKCRLS
DQEQARISFTERDLCISEQLSKLEFESINRENFRQIADCIDDVLARSGLLPDRIDSVFLTGGTSRIPHIQALFAERFGRE
KLHTRQAFTSVVHGLGASVPLFTWS

Sequences:

>Translated_425_residues
MQPVFGIDFGTTNSALSIYHNGTVEVVAVDGTDRSGELMRSVLYFNEDNEIFAGNEAVRQYVGDGAAGRFMQSIKTFLPN
TSFDSTEIFGKRYAIDDLVAIILRQIKARGETHLGCPVERVVLGRPVLFSTDPAKDAVAEQRLEKAARKAGFKQIRFQYE
PVAAALAFEETLQPGQERIVFIGDFGGGTSDFSVIRVKGGAFARSDRRSDVLSLGGVYVAGDKFDSQIMWDKVAHYFGRT
ARYKTLGKDDWVTVPRSIIYTLCQWHRIPLLRARKTREHIRVIKGSTDNRQAIQHLENIIDDNFGYFLFQAIESAKCRLS
DQEQARISFTERDLCISEQLSKLEFESINRENFRQIADCIDDVLARSGLLPDRIDSVFLTGGTSRIPHIQALFAERFGRE
KLHTRQAFTSVVHGLGASVPLFTWS
>Mature_425_residues
MQPVFGIDFGTTNSALSIYHNGTVEVVAVDGTDRSGELMRSVLYFNEDNEIFAGNEAVRQYVGDGAAGRFMQSIKTFLPN
TSFDSTEIFGKRYAIDDLVAIILRQIKARGETHLGCPVERVVLGRPVLFSTDPAKDAVAEQRLEKAARKAGFKQIRFQYE
PVAAALAFEETLQPGQERIVFIGDFGGGTSDFSVIRVKGGAFARSDRRSDVLSLGGVYVAGDKFDSQIMWDKVAHYFGRT
ARYKTLGKDDWVTVPRSIIYTLCQWHRIPLLRARKTREHIRVIKGSTDNRQAIQHLENIIDDNFGYFLFQAIESAKCRLS
DQEQARISFTERDLCISEQLSKLEFESINRENFRQIADCIDDVLARSGLLPDRIDSVFLTGGTSRIPHIQALFAERFGRE
KLHTRQAFTSVVHGLGASVPLFTWS

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI16507237, Length=426, Percent_Identity=29.3427230046948, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI24234686, Length=422, Percent_Identity=23.9336492890995, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5729877, Length=422, Percent_Identity=24.1706161137441, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI34419635, Length=428, Percent_Identity=24.0654205607477, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI13676857, Length=440, Percent_Identity=22.5, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI167466173, Length=423, Percent_Identity=23.1678486997636, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI194248072, Length=423, Percent_Identity=23.1678486997636, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI124256496, Length=420, Percent_Identity=22.3809523809524, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI24234688, Length=424, Percent_Identity=23.1132075471698, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI87082035, Length=454, Percent_Identity=23.3480176211454, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786196, Length=428, Percent_Identity=25.9345794392523, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786870, Length=194, Percent_Identity=31.4432989690722, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788875, Length=418, Percent_Identity=25.1196172248804, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17568549, Length=428, Percent_Identity=26.8691588785047, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17534771, Length=429, Percent_Identity=26.5734265734266, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17534015, Length=437, Percent_Identity=24.2562929061785, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17534013, Length=437, Percent_Identity=24.2562929061785, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562024, Length=425, Percent_Identity=24.9411764705882, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17541098, Length=420, Percent_Identity=22.6190476190476, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17507981, Length=437, Percent_Identity=23.1121281464531, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322426, Length=424, Percent_Identity=24.5283018867925, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322505, Length=421, Percent_Identity=23.2779097387173, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323004, Length=445, Percent_Identity=23.1460674157303, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6319314, Length=445, Percent_Identity=23.1460674157303, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324120, Length=435, Percent_Identity=23.448275862069, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319972, Length=435, Percent_Identity=23.448275862069, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320805, Length=421, Percent_Identity=23.2779097387173, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17737941, Length=439, Percent_Identity=24.6013667425968, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24653595, Length=426, Percent_Identity=24.6478873239437, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24647034, Length=428, Percent_Identity=24.0654205607477, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647038, Length=428, Percent_Identity=24.0654205607477, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647036, Length=428, Percent_Identity=24.0654205607477, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17737967, Length=428, Percent_Identity=24.0654205607477, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571721, Length=428, Percent_Identity=24.0654205607477, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571719, Length=428, Percent_Identity=24.0654205607477, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571678, Length=429, Percent_Identity=24.009324009324, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17647515, Length=424, Percent_Identity=23.8207547169811, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646318, Length=429, Percent_Identity=24.009324009324, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646324, Length=429, Percent_Identity=24.009324009324, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646322, Length=429, Percent_Identity=24.009324009324, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646137, Length=429, Percent_Identity=23.7762237762238, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24646135, Length=429, Percent_Identity=23.7762237762238, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17738165, Length=425, Percent_Identity=23.2941176470588, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641406, Length=250, Percent_Identity=29.2, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641408, Length=250, Percent_Identity=29.2, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641402, Length=250, Percent_Identity=29.2, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641404, Length=250, Percent_Identity=29.2, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 47739; Mature: 47739

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPVFGIDFGTTNSALSIYHNGTVEVVAVDGTDRSGELMRSVLYFNEDNEIFAGNEAVRQ
CCCCEECCCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCEECCCHHHHH
YVGDGAAGRFMQSIKTFLPNTSFDSTEIFGKRYAIDDLVAIILRQIKARGETHLGCPVER
HHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VVLGRPVLFSTDPAKDAVAEQRLEKAARKAGFKQIRFQYEPVAAALAFEETLQPGQERIV
HHCCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHEEEECHHHHHHHHHHHHCCCCCEEE
FIGDFGGGTSDFSVIRVKGGAFARSDRRSDVLSLGGVYVAGDKFDSQIMWDKVAHYFGRT
EEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCC
ARYKTLGKDDWVTVPRSIIYTLCQWHRIPLLRARKTREHIRVIKGSTDNRQAIQHLENII
HHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHH
DDNFGYFLFQAIESAKCRLSDQEQARISFTERDLCISEQLSKLEFESINRENFRQIADCI
CCCCHHHHHHHHHHHHCCCCCCHHHHEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DDVLARSGLLPDRIDSVFLTGGTSRIPHIQALFAERFGREKLHTRQAFTSVVHGLGASVP
HHHHHHCCCCHHHHCEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
LFTWS
EEECC
>Mature Secondary Structure
MQPVFGIDFGTTNSALSIYHNGTVEVVAVDGTDRSGELMRSVLYFNEDNEIFAGNEAVRQ
CCCCEECCCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCEECCCHHHHH
YVGDGAAGRFMQSIKTFLPNTSFDSTEIFGKRYAIDDLVAIILRQIKARGETHLGCPVER
HHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VVLGRPVLFSTDPAKDAVAEQRLEKAARKAGFKQIRFQYEPVAAALAFEETLQPGQERIV
HHCCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHEEEECHHHHHHHHHHHHCCCCCEEE
FIGDFGGGTSDFSVIRVKGGAFARSDRRSDVLSLGGVYVAGDKFDSQIMWDKVAHYFGRT
EEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCC
ARYKTLGKDDWVTVPRSIIYTLCQWHRIPLLRARKTREHIRVIKGSTDNRQAIQHLENII
HHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHH
DDNFGYFLFQAIESAKCRLSDQEQARISFTERDLCISEQLSKLEFESINRENFRQIADCI
CCCCHHHHHHHHHHHHCCCCCCHHHHEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DDVLARSGLLPDRIDSVFLTGGTSRIPHIQALFAERFGREKLHTRQAFTSVVHGLGASVP
HHHHHHCCCCHHHHCEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
LFTWS
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA