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The map label for this gene is gtaB [H]

Identifier: 189423578

GI number: 189423578

Start: 481819

End: 482694

Strand: Reverse

Name: gtaB [H]

Synonym: Glov_0507

Alternate gene names: 189423578

Gene position: 482694-481819 (Counterclockwise)

Preceding gene: 189423579

Following gene: 189423575

Centisome position: 12.32

GC content: 57.88

Gene sequence:

>876_bases
ATGAAAGTCCGCAAGGCGATCTTTCCGGTGGCCGGCCTGGGAACCCGCTTCCTGCCTGCCACCAAATCATCTCCCAAAGA
GATGCTACCGCTGATCGACAAGCCGCTGGTGCAGTATGTGGTTGAAGAGGCGGTGGCAGCCGGTATTGAGCAGATCATCT
TTGTGACCGGCCGCACCAAGCGTTCCATTGAGGACCACTTTGACAGCTCACCCGAGCTGGAAAACCATCTTGAAGAAAAG
GGCAAAGACGAGACCCTGCAGGCGGTACGCTGTATTGCCGACCTGGTTGATATCTTTTATGTGCGCCAGAAAAAGGCCCT
GGGGCTGGGGCATGCCATCCTCTGTGCCCGCGACTTTATCGGCAATGAACCGTTTGCCGTGTTGCTGGGGGACGACATCA
TCGACACCCCTGGCAGCGCCCCCTGCCTGCGGCAGCTGCTGGATGTCTACGAGCACTATAAAGGCAGTGTGCTGGCCCTT
GAGCAGGTGCCGATGGAACAGATCTCCTCCTACGGCTGTGTTGCGGTCAACCGGATCACTGATCATGTGATGGAGGTGAC
CGATATGGTGGAAAAACCGCCACAGGCGGAGGCCCCTTCCAACCTTGCCATCATAGGTCGCTACGTCTTGACCCCGGCCA
TCTTCCCGCTTCTGGAACAGCAGCAACCGGGCCGGGGCGGCGAGATCCAGCTGACCGACGCCATCAAACGGCTGTCTCAG
GACGAGGCGGTGTATGGTTGTCTGTTTGAAGGGTTACGCCATGACTGCGGGGACAAGCTGGGGTTCCTGAAGGCAACGGT
GGATCTGGCACTGAAGCGGGATGAGTTCAAGGAGGATTTTACCGCCTACCTGAAACAGCGGCTGGGATGTTTGTAA

Upstream 100 bases:

>100_bases
CGCGATCACCCCGGTACCGGGCGGTGTTGGCCCGATGACCATTGCCATGCTGCTGCAAAATACGCTTGAATCTGCCCAAC
GGGCTGCAACGAGGTAATCC

Downstream 100 bases:

>100_bases
GCTGATAAGGGCGAGGCCTGCTGCCTCGCCCTACTTTTCGTTCAACAGTTTTTTAACCAGGTTTTCGATCACCTTGCCGG
CCTGATCAGAAAAGCCCATG

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKVRKAIFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVAAGIEQIIFVTGRTKRSIEDHFDSSPELENHLEEK
GKDETLQAVRCIADLVDIFYVRQKKALGLGHAILCARDFIGNEPFAVLLGDDIIDTPGSAPCLRQLLDVYEHYKGSVLAL
EQVPMEQISSYGCVAVNRITDHVMEVTDMVEKPPQAEAPSNLAIIGRYVLTPAIFPLLEQQQPGRGGEIQLTDAIKRLSQ
DEAVYGCLFEGLRHDCGDKLGFLKATVDLALKRDEFKEDFTAYLKQRLGCL

Sequences:

>Translated_291_residues
MKVRKAIFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVAAGIEQIIFVTGRTKRSIEDHFDSSPELENHLEEK
GKDETLQAVRCIADLVDIFYVRQKKALGLGHAILCARDFIGNEPFAVLLGDDIIDTPGSAPCLRQLLDVYEHYKGSVLAL
EQVPMEQISSYGCVAVNRITDHVMEVTDMVEKPPQAEAPSNLAIIGRYVLTPAIFPLLEQQQPGRGGEIQLTDAIKRLSQ
DEAVYGCLFEGLRHDCGDKLGFLKATVDLALKRDEFKEDFTAYLKQRLGCL
>Mature_291_residues
MKVRKAIFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVAAGIEQIIFVTGRTKRSIEDHFDSSPELENHLEEK
GKDETLQAVRCIADLVDIFYVRQKKALGLGHAILCARDFIGNEPFAVLLGDDIIDTPGSAPCLRQLLDVYEHYKGSVLAL
EQVPMEQISSYGCVAVNRITDHVMEVTDMVEKPPQAEAPSNLAIIGRYVLTPAIFPLLEQQQPGRGGEIQLTDAIKRLSQ
DEAVYGCLFEGLRHDCGDKLGFLKATVDLALKRDEFKEDFTAYLKQRLGCL

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=265, Percent_Identity=25.6603773584906, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI11761619, Length=265, Percent_Identity=25.6603773584906, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787488, Length=295, Percent_Identity=46.4406779661017, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1788355, Length=278, Percent_Identity=43.1654676258993, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1790224, Length=229, Percent_Identity=25.764192139738, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788351, Length=291, Percent_Identity=23.0240549828179, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32270; Mature: 32270

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRKAIFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVAAGIEQIIFVTGRTK
CCCHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCH
RSIEDHFDSSPELENHLEEKGKDETLQAVRCIADLVDIFYVRQKKALGLGHAILCARDFI
HHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GNEPFAVLLGDDIIDTPGSAPCLRQLLDVYEHYKGSVLALEQVPMEQISSYGCVAVNRIT
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHCCHHHHHCCCCHHHHHHH
DHVMEVTDMVEKPPQAEAPSNLAIIGRYVLTPAIFPLLEQQQPGRGGEIQLTDAIKRLSQ
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
DEAVYGCLFEGLRHDCGDKLGFLKATVDLALKRDEFKEDFTAYLKQRLGCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVRKAIFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVAAGIEQIIFVTGRTK
CCCHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCH
RSIEDHFDSSPELENHLEEKGKDETLQAVRCIADLVDIFYVRQKKALGLGHAILCARDFI
HHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GNEPFAVLLGDDIIDTPGSAPCLRQLLDVYEHYKGSVLALEQVPMEQISSYGCVAVNRIT
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHCCHHHHHCCCCHHHHHHH
DHVMEVTDMVEKPPQAEAPSNLAIIGRYVLTPAIFPLLEQQQPGRGGEIQLTDAIKRLSQ
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
DEAVYGCLFEGLRHDCGDKLGFLKATVDLALKRDEFKEDFTAYLKQRLGCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]