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The map label for this gene is abgR [H]

Identifier: 189353925

GI number: 189353925

Start: 2241348

End: 2242268

Strand: Direct

Name: abgR [H]

Synonym: BMULJ_05178

Alternate gene names: 189353925

Gene position: 2241348-2242268 (Clockwise)

Preceding gene: 189353924

Following gene: 189353926

Centisome position: 90.63

GC content: 70.68

Gene sequence:

>921_bases
ATGACGCGCATCCGAAATCACCTGAACGTCGCGCAACTGCAGGCCTTCGTCTGCGCCGCGCATCACAAGAGCCTGCGCGC
CGCCGCGCGCGAACTCGGCGTCACGCAGCCGGCGATCACGCATACGATCCGCGAGCTCGAAACCGCGCTCAACGCCGAGT
TGCTCGTGCGCAGCGTGCGCGGCGTCGAGCTGACGGCCTGCGGCCACGCGCTGCTGCCGCGCGCGGAGCAGCTGCTCGGC
GACATGCGCCGCACGCTCGAAGCGGTCGAACAGGTGAAGGGCGAAATGTCCGGGCGCGTCGCGGTCGGCACGATGCCGTC
GATCGCGCTGACGGCGCTGCCGCACGCGGTCACCGCGTTTCGCCGTGCGATGCCGAACGTGAGCCTGCATCTCGAGGAAG
TGACGGTGCCCGACGCGCTCGCGCAGCTGCGCAACGGCACGCTCGACATCGCCGCGATGCACCACGTGCCGGCGCTCGAC
CGCGATTTCACGCAGTCGCCGCTGCTGTCGACCGAGTTCGTCGTCGCGATGCGCGACGGCCATCCGCTCGCGCACGCGCG
CCGTTTAGAGGAATTGCTCGACGCGGAGTGGATCGTCACGGTCGGCGCCGAGCAGTTTCCGCACAGCGTGATGACGGCGA
TGTTCGACGCGCGTGGGCTGCCGCTGCCGAAGCGCCTGCTGCGCTCGCCGATGTCGTTCGCGGTCACGCTCGGGCTCGTC
GCGCGCTCGGACGTGATCGGCTGCTTCACGCGCCCGCTCGCGGCGATGGTCGCGCCGCTCGGCATCCGCACGGCCGAGCT
CGACGACGCGATGCCGCGCTTCGACCTGTCGATCATCGCGCGGCGCGACCTGCTGCCGACGCCCGCCGTGTCGCAGTTCG
TCGCGTGTCTGCGGCGCGCGGTCAACGAAACGCTCGGCTGA

Upstream 100 bases:

>100_bases
CGCGCGGCGCGCTACCCTATCGGTCTTCGCACCGCCGCCCGCGGCGAGCCGGCCCCGTGCACCGGCCGCCGCCGGGCGCG
CCCGCTCCCGAACCCGACCG

Downstream 100 bases:

>100_bases
AGCGTTCCGGAAGGCAGGCACGCGCGACAAGTCGCCGCGCGGCCGCCCGATCCGGTATCGGGGCATGTCCTAGGCGCCGC
GCCGGTATTTTGTCTTGATA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTRIRNHLNVAQLQAFVCAAHHKSLRAAARELGVTQPAITHTIRELETALNAELLVRSVRGVELTACGHALLPRAEQLLG
DMRRTLEAVEQVKGEMSGRVAVGTMPSIALTALPHAVTAFRRAMPNVSLHLEEVTVPDALAQLRNGTLDIAAMHHVPALD
RDFTQSPLLSTEFVVAMRDGHPLAHARRLEELLDAEWIVTVGAEQFPHSVMTAMFDARGLPLPKRLLRSPMSFAVTLGLV
ARSDVIGCFTRPLAAMVAPLGIRTAELDDAMPRFDLSIIARRDLLPTPAVSQFVACLRRAVNETLG

Sequences:

>Translated_306_residues
MTRIRNHLNVAQLQAFVCAAHHKSLRAAARELGVTQPAITHTIRELETALNAELLVRSVRGVELTACGHALLPRAEQLLG
DMRRTLEAVEQVKGEMSGRVAVGTMPSIALTALPHAVTAFRRAMPNVSLHLEEVTVPDALAQLRNGTLDIAAMHHVPALD
RDFTQSPLLSTEFVVAMRDGHPLAHARRLEELLDAEWIVTVGAEQFPHSVMTAMFDARGLPLPKRLLRSPMSFAVTLGLV
ARSDVIGCFTRPLAAMVAPLGIRTAELDDAMPRFDLSIIARRDLLPTPAVSQFVACLRRAVNETLG
>Mature_305_residues
TRIRNHLNVAQLQAFVCAAHHKSLRAAARELGVTQPAITHTIRELETALNAELLVRSVRGVELTACGHALLPRAEQLLGD
MRRTLEAVEQVKGEMSGRVAVGTMPSIALTALPHAVTAFRRAMPNVSLHLEEVTVPDALAQLRNGTLDIAAMHHVPALDR
DFTQSPLLSTEFVVAMRDGHPLAHARRLEELLDAEWIVTVGAEQFPHSVMTAMFDARGLPLPKRLLRSPMSFAVTLGLVA
RSDVIGCFTRPLAAMVAPLGIRTAELDDAMPRFDLSIIARRDLLPTPAVSQFVACLRRAVNETLG

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=297, Percent_Identity=27.9461279461279, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI145693105, Length=303, Percent_Identity=28.3828382838284, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789506, Length=177, Percent_Identity=28.2485875706215, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790399, Length=178, Percent_Identity=30.3370786516854, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87081904, Length=237, Percent_Identity=27.0042194092827, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788887, Length=177, Percent_Identity=28.8135593220339, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788706, Length=128, Percent_Identity=33.59375, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=173, Percent_Identity=29.4797687861272, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788748, Length=145, Percent_Identity=28.9655172413793, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=266, Percent_Identity=24.812030075188, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367136, Length=191, Percent_Identity=28.7958115183246, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789440, Length=145, Percent_Identity=32.4137931034483, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33357; Mature: 33226

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS50931 HTH_LYSR ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIRNHLNVAQLQAFVCAAHHKSLRAAARELGVTQPAITHTIRELETALNAELLVRSVR
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GVELTACGHALLPRAEQLLGDMRRTLEAVEQVKGEMSGRVAVGTMPSIALTALPHAVTAF
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHH
RRAMPNVSLHLEEVTVPDALAQLRNGTLDIAAMHHVPALDRDFTQSPLLSTEFVVAMRDG
HHHCCCCEEEEHHCCHHHHHHHHCCCCEEEEHHHHCCCCCCCCCCCCCCCHHEEEEECCC
HPLAHARRLEELLDAEWIVTVGAEQFPHSVMTAMFDARGLPLPKRLLRSPMSFAVTLGLV
CCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHH
ARSDVIGCFTRPLAAMVAPLGIRTAELDDAMPRFDLSIIARRDLLPTPAVSQFVACLRRA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
VNETLG
HHHCCC
>Mature Secondary Structure 
TRIRNHLNVAQLQAFVCAAHHKSLRAAARELGVTQPAITHTIRELETALNAELLVRSVR
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GVELTACGHALLPRAEQLLGDMRRTLEAVEQVKGEMSGRVAVGTMPSIALTALPHAVTAF
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHH
RRAMPNVSLHLEEVTVPDALAQLRNGTLDIAAMHHVPALDRDFTQSPLLSTEFVVAMRDG
HHHCCCCEEEEHHCCHHHHHHHHCCCCEEEEHHHHCCCCCCCCCCCCCCCHHEEEEECCC
HPLAHARRLEELLDAEWIVTVGAEQFPHSVMTAMFDARGLPLPKRLLRSPMSFAVTLGLV
CCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHH
ARSDVIGCFTRPLAAMVAPLGIRTAELDDAMPRFDLSIIARRDLLPTPAVSQFVACLRRA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
VNETLG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]