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The map label for this gene is pbuG [H]

Identifier: 189353924

GI number: 189353924

Start: 2239722

End: 2241110

Strand: Direct

Name: pbuG [H]

Synonym: BMULJ_05177

Alternate gene names: 189353924

Gene position: 2239722-2241110 (Clockwise)

Preceding gene: 189353923

Following gene: 189353925

Centisome position: 90.56

GC content: 68.32

Gene sequence:

>1389_bases
ATGAGTGATACCCCGGTGCAGCCGACGGTCGGCGTCGGCACGGAAGAAAACGACTTCGGCACGCCGGGCGTCATCGACCG
GTATTTCGGCATATCGACGCGCGGCAGCACGCAGCGCCGCGAGATCGTCGCGGGCGTAACGACGTTCCTCGCGATGGTTT
ATTCGGTCTTCGTCGTGCCGGGCATGTTCGGCAAGGCCGGCTTCGACACGAGCGCCGTGTTCGTCGCGGTCTGCCTGACG
ACCGCGTTCGGTTCGCTGCTGATGGGCCTGTGGGCGAAGCTGCCGATCGCGATCGGCTGCGCGATCTCGCTGACGGCCTT
CACCGCGTTCGGCCTCGTGCTCGGCAAGGGGCTGCATCCGACCGTCGCGCTCGGCGCGGTGTTTCTGATGGGTCTCGTGT
TCACCGGCATCTCGATCACCGGCGTGCGCTCGTGGATCCTGCGCAATCTGCCCGCGGGCGTCGCGCACGGCACCGGCATC
GGCATCGGCCTGTTCCTGCTGCTGATCGCGTCGAACGACGTCGGCCTCGTGATCAAGAACCCCGGCGCCGGCCTGCCGGT
CTCGCTCGGTCAGATCACCGCGTTCCCGGTCATCATGTCGGTGATCGGCCTGGCGGCGATCTTCGGCCTCGAGAAGCGCC
GCGTGCCGGGCGGCATCCTGCTCGTCGTGATCGCGATCTCGCTGTTCGGCCTCGGGTTCGATCCGGCGGTGAAGTACCGC
GGCGTCTTCGCGCTGCCGTCGCTGAGCACGCCGGGCCATGCATCGCTGATCGGCGCGATGGACCTTCGCGGCGCGCTGTC
GATGGCCGTGCTGCCGAGCGTGCTCGCCCTCGTGATGACGGCCGTGTTCGACGCGACCGGCACGATCCGCGCGGTTGCCG
GCCAGGCCGGTCAGCTCGACGAAAACGGCCGCATCGTCAACGGCGGCCGCGCGCTGACCGCCGATTCGGTCAGCTCGATC
TTCTCCGGCTTCCTCGGCGGCGCACCGGCGGCGGCCTATATCGAATCGAGCGTCGGCGTGGCCGCCGGCGCGAAGACGGG
CCTCGCGGCCGCGGTGGTCGGCCTGCTGTTCCTCGTCGTGATGTTCTTCTCGCCGCTCGCCGCGCTCGTGCCGTCGTACG
CGACCGCGCCCGCGCTGATGTACGTCGGGCTGCTGATGCTCGGCAGCGTCGCGAAGCTGCATATGGACGACATGGTCGAC
GCGATGTCGGGGCTCGTCTGCGCGGTGTTCATCGTGCTGACCGCGAACATCGTGACGGGCATCATGCTCGGCTTCTCGAC
GCTCGTGATCGGCCGCATCGCGAGCGGCGAATTCCGCAAGCTGAATGCGGGCACCGTGATCATCGCGGCCGTGCTCGTCA
CGTTCTATCTCGGCGGCTGGGCGATCTGA

Upstream 100 bases:

>100_bases
ATTCGTCCCCACGACGATGCCGACATTCCAACCAGATACGAGACACCCTGACGACGGCGCGCAACGCGCCGTTTCAGCAC
GCTGATAAAGGAGCAAGCTC

Downstream 100 bases:

>100_bases
CCACGCACCGCGCGTGCCGCGGCGGCGGGCGCGCATCCCGATAACGGCGTCTCCTCCACCATCATCGTTGATGGCCTCCG
GGCCCGGAAACGCAGGTTTC

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSDTPVQPTVGVGTEENDFGTPGVIDRYFGISTRGSTQRREIVAGVTTFLAMVYSVFVVPGMFGKAGFDTSAVFVAVCLT
TAFGSLLMGLWAKLPIAIGCAISLTAFTAFGLVLGKGLHPTVALGAVFLMGLVFTGISITGVRSWILRNLPAGVAHGTGI
GIGLFLLLIASNDVGLVIKNPGAGLPVSLGQITAFPVIMSVIGLAAIFGLEKRRVPGGILLVVIAISLFGLGFDPAVKYR
GVFALPSLSTPGHASLIGAMDLRGALSMAVLPSVLALVMTAVFDATGTIRAVAGQAGQLDENGRIVNGGRALTADSVSSI
FSGFLGGAPAAAYIESSVGVAAGAKTGLAAAVVGLLFLVVMFFSPLAALVPSYATAPALMYVGLLMLGSVAKLHMDDMVD
AMSGLVCAVFIVLTANIVTGIMLGFSTLVIGRIASGEFRKLNAGTVIIAAVLVTFYLGGWAI

Sequences:

>Translated_462_residues
MSDTPVQPTVGVGTEENDFGTPGVIDRYFGISTRGSTQRREIVAGVTTFLAMVYSVFVVPGMFGKAGFDTSAVFVAVCLT
TAFGSLLMGLWAKLPIAIGCAISLTAFTAFGLVLGKGLHPTVALGAVFLMGLVFTGISITGVRSWILRNLPAGVAHGTGI
GIGLFLLLIASNDVGLVIKNPGAGLPVSLGQITAFPVIMSVIGLAAIFGLEKRRVPGGILLVVIAISLFGLGFDPAVKYR
GVFALPSLSTPGHASLIGAMDLRGALSMAVLPSVLALVMTAVFDATGTIRAVAGQAGQLDENGRIVNGGRALTADSVSSI
FSGFLGGAPAAAYIESSVGVAAGAKTGLAAAVVGLLFLVVMFFSPLAALVPSYATAPALMYVGLLMLGSVAKLHMDDMVD
AMSGLVCAVFIVLTANIVTGIMLGFSTLVIGRIASGEFRKLNAGTVIIAAVLVTFYLGGWAI
>Mature_461_residues
SDTPVQPTVGVGTEENDFGTPGVIDRYFGISTRGSTQRREIVAGVTTFLAMVYSVFVVPGMFGKAGFDTSAVFVAVCLTT
AFGSLLMGLWAKLPIAIGCAISLTAFTAFGLVLGKGLHPTVALGAVFLMGLVFTGISITGVRSWILRNLPAGVAHGTGIG
IGLFLLLIASNDVGLVIKNPGAGLPVSLGQITAFPVIMSVIGLAAIFGLEKRRVPGGILLVVIAISLFGLGFDPAVKYRG
VFALPSLSTPGHASLIGAMDLRGALSMAVLPSVLALVMTAVFDATGTIRAVAGQAGQLDENGRIVNGGRALTADSVSSIF
SGFLGGAPAAAYIESSVGVAAGAKTGLAAAVVGLLFLVVMFFSPLAALVPSYATAPALMYVGLLMLGSVAKLHMDDMVDA
MSGLVCAVFIVLTANIVTGIMLGFSTLVIGRIASGEFRKLNAGTVIIAAVLVTFYLGGWAI

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790499, Length=442, Percent_Identity=71.4932126696833, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI48994909, Length=440, Percent_Identity=72.0454545454545, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI87082309, Length=443, Percent_Identity=36.7945823927765, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI1790150, Length=431, Percent_Identity=38.2830626450116, Blast_Score=271, Evalue=9e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47007; Mature: 46875

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDTPVQPTVGVGTEENDFGTPGVIDRYFGISTRGSTQRREIVAGVTTFLAMVYSVFVVP
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC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HHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]