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The map label for this gene is aer [H]

Identifier: 189353912

GI number: 189353912

Start: 2224403

End: 2225947

Strand: Reverse

Name: aer [H]

Synonym: BMULJ_05164

Alternate gene names: 189353912

Gene position: 2225947-2224403 (Counterclockwise)

Preceding gene: 189353913

Following gene: 189353909

Centisome position: 90.0

GC content: 68.67

Gene sequence:

>1545_bases
ATGCGCAACAACCAGCCTGTTACCCAACAAGAATTCGATTTTCCCGACGACGCGACGCTGATGTCGACGACCGATGCCGA
CAGCGTCATCACGTATGCGAACACCGCGTTCGCCCAGGTCAGCGGCTTTTCGAACGACGAACTCGTCGGTCAGCCGCACA
ACGTCGTGCGCCATCCCGACATGCCGCGCGACGCGTTCGCCGATATGTGGGCGACGCTCAGGCGCGGCGAGCCGTGGACC
GCGCTCGTCAAGAACCGCCGCAAGAACGGCGATCACTACTGGGTGCGCGCGAATGCGGTGCCGATGATGCGCGACGGCGT
GCCGGTCGGCTACATGTCGGTGCGCACCAAGCCGCCGCGCGACGAAATCGATGGCGCCGAGGCGCTGTATCGCGCGATTC
GCGAGGGCAAGGCGGGCCGTCGCCGGTTTCACAAGGGGCTCGTCATCCGTACGGGGCTACTGCGCGTCGCGTCGCTGACG
CAGACGATGTCGGTGCGCACGCGCGTGCACGCGGCGCTCGCCGTGCTCGCACCGGCGGTCGTCGGCGCCGCATATGCATG
CGGACTCTCGGGCGCGGGGCTTGCCGCATTCGGCGCGGCGGCTGTCGGTGCGACCGCCGTCGCCGCGCTGTGGCTCGACG
CGCAGATCGTGCGTCCGCTGAAGCGGCTGCACGACCAGGCGCTGAACGTCGCGACCGGCGCGAGCCGGCGCGGCGTGCGG
ATGAACCGCGTCGACGAGATCGGCATGACGCTGCGCACGATCAACCAGCTCGGGCTGATGCTGCGCTGGCTCGTCGACGA
CGTCACCGAGCAGGTGCACACCGTGCAGCGCGCGAGCAACGAGATCGCGCAGGGCAACGACGATCTGAGCGCACGCACCG
AACAGGCCGCATCGAGCGTGCAGGAGACGGCCGCGTCGATGGCCGAGATGACGACGACCGTCGACAGCAATGCGGAAACG
GCACTGCAGGCGAACCGGCTCGCGATGTCGGCGAGCGATGCGGCCGAGCGCGGCGGTCAAGCCGTGTCGGACGTCGTCGC
GACGATGCGCGAGATCACCGACAGCTCGCGCAAGATCGCCGACATCATCGGCGTGATCGACGGCATCGCGTTCCAGACCA
ACATCCTCGCGCTGAACGCGGCCGTCGAAGCGGCGCGCGCGGGCGAGCAGGGGCGCGGCTTCGCGGTCGTCGCCGGCGAA
GTGCGTGCGCTCGCGCAGCGCAGCGCGCATGCGGCGAAAGAGATCAAGACGCTGATCGGCGCGAGCGTCGAGCGTGTCGA
ATCGGGTGCGCGGCGCGTGGATGAAGCGGGCCGCACGATGGAGGACATCGTCGCGCAGGTGAAGCGCGTGTCGGATTTGA
TTGCGGCGATCAGCGCGTCGACGGCCGAGCAGAGCACCGGCGTCGCGCAGGTCGATCAGGCGGTCGTGCATCTCGACACG
ATCACGCAGCAGAATGCGGCGCTCGTCGAACAAAGTGCGGCGGCGTCGGCGAGCCTGAAGCAGCAGGCCGCGCGGCTCGT
GGATGCGATCGAGGTGTTTCGCTGA

Upstream 100 bases:

>100_bases
CAGTAACGGGAAGGCCGTCATCGAGCGATCCATCGCTGTCCGGCTACGGAGCACGGTCGTCCGCATTGCGCGGTCGATCG
CTCCGCCTTTCGGAGCCCGC

Downstream 100 bases:

>100_bases
ACGCGTGCGACGCGAGGAGGAAAGTGACGCGGGCGCGGCGGAGAGGGCACCGGCCCGCGTCGGGTCCGCCCGGTTCCGGC
CGGGCGGGCCGCGCCGTCAG

Product: aerotaxis receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MRNNQPVTQQEFDFPDDATLMSTTDADSVITYANTAFAQVSGFSNDELVGQPHNVVRHPDMPRDAFADMWATLRRGEPWT
ALVKNRRKNGDHYWVRANAVPMMRDGVPVGYMSVRTKPPRDEIDGAEALYRAIREGKAGRRRFHKGLVIRTGLLRVASLT
QTMSVRTRVHAALAVLAPAVVGAAYACGLSGAGLAAFGAAAVGATAVAALWLDAQIVRPLKRLHDQALNVATGASRRGVR
MNRVDEIGMTLRTINQLGLMLRWLVDDVTEQVHTVQRASNEIAQGNDDLSARTEQAASSVQETAASMAEMTTTVDSNAET
ALQANRLAMSASDAAERGGQAVSDVVATMREITDSSRKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRALAQRSAHAAKEIKTLIGASVERVESGARRVDEAGRTMEDIVAQVKRVSDLIAAISASTAEQSTGVAQVDQAVVHLDT
ITQQNAALVEQSAAASASLKQQAARLVDAIEVFR

Sequences:

>Translated_514_residues
MRNNQPVTQQEFDFPDDATLMSTTDADSVITYANTAFAQVSGFSNDELVGQPHNVVRHPDMPRDAFADMWATLRRGEPWT
ALVKNRRKNGDHYWVRANAVPMMRDGVPVGYMSVRTKPPRDEIDGAEALYRAIREGKAGRRRFHKGLVIRTGLLRVASLT
QTMSVRTRVHAALAVLAPAVVGAAYACGLSGAGLAAFGAAAVGATAVAALWLDAQIVRPLKRLHDQALNVATGASRRGVR
MNRVDEIGMTLRTINQLGLMLRWLVDDVTEQVHTVQRASNEIAQGNDDLSARTEQAASSVQETAASMAEMTTTVDSNAET
ALQANRLAMSASDAAERGGQAVSDVVATMREITDSSRKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRALAQRSAHAAKEIKTLIGASVERVESGARRVDEAGRTMEDIVAQVKRVSDLIAAISASTAEQSTGVAQVDQAVVHLDT
ITQQNAALVEQSAAASASLKQQAARLVDAIEVFR
>Mature_514_residues
MRNNQPVTQQEFDFPDDATLMSTTDADSVITYANTAFAQVSGFSNDELVGQPHNVVRHPDMPRDAFADMWATLRRGEPWT
ALVKNRRKNGDHYWVRANAVPMMRDGVPVGYMSVRTKPPRDEIDGAEALYRAIREGKAGRRRFHKGLVIRTGLLRVASLT
QTMSVRTRVHAALAVLAPAVVGAAYACGLSGAGLAAFGAAAVGATAVAALWLDAQIVRPLKRLHDQALNVATGASRRGVR
MNRVDEIGMTLRTINQLGLMLRWLVDDVTEQVHTVQRASNEIAQGNDDLSARTEQAASSVQETAASMAEMTTTVDSNAET
ALQANRLAMSASDAAERGGQAVSDVVATMREITDSSRKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRALAQRSAHAAKEIKTLIGASVERVESGARRVDEAGRTMEDIVAQVKRVSDLIAAISASTAEQSTGVAQVDQAVVHLDT
ITQQNAALVEQSAAASASLKQQAARLVDAIEVFR

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=521, Percent_Identity=51.2476007677543, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI2367378, Length=310, Percent_Identity=54.1935483870968, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=53.9735099337748, Blast_Score=261, Evalue=6e-71,
Organism=Escherichia coli, GI1788194, Length=309, Percent_Identity=50.8090614886731, Blast_Score=259, Evalue=4e-70,
Organism=Escherichia coli, GI1787690, Length=328, Percent_Identity=47.5609756097561, Blast_Score=258, Evalue=8e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 54880; Mature: 54880

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNQPVTQQEFDFPDDATLMSTTDADSVITYANTAFAQVSGFSNDELVGQPHNVVRHPD
CCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCC
MPRDAFADMWATLRRGEPWTALVKNRRKNGDHYWVRANAVPMMRDGVPVGYMSVRTKPPR
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCEEEECCCCCC
DEIDGAEALYRAIREGKAGRRRFHKGLVIRTGLLRVASLTQTMSVRTRVHAALAVLAPAV
CCCCHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAAYACGLSGAGLAAFGAAAVGATAVAALWLDAQIVRPLKRLHDQALNVATGASRRGVR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
MNRVDEIGMTLRTINQLGLMLRWLVDDVTEQVHTVQRASNEIAQGNDDLSARTEQAASSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QETAASMAEMTTTVDSNAETALQANRLAMSASDAAERGGQAVSDVVATMREITDSSRKIA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAQRSAHAAKEIKTLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
ASVERVESGARRVDEAGRTMEDIVAQVKRVSDLIAAISASTAEQSTGVAQVDQAVVHLDT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHH
ITQQNAALVEQSAAASASLKQQAARLVDAIEVFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRNNQPVTQQEFDFPDDATLMSTTDADSVITYANTAFAQVSGFSNDELVGQPHNVVRHPD
CCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCC
MPRDAFADMWATLRRGEPWTALVKNRRKNGDHYWVRANAVPMMRDGVPVGYMSVRTKPPR
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCEEEECCCCCC
DEIDGAEALYRAIREGKAGRRRFHKGLVIRTGLLRVASLTQTMSVRTRVHAALAVLAPAV
CCCCHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAAYACGLSGAGLAAFGAAAVGATAVAALWLDAQIVRPLKRLHDQALNVATGASRRGVR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
MNRVDEIGMTLRTINQLGLMLRWLVDDVTEQVHTVQRASNEIAQGNDDLSARTEQAASSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QETAASMAEMTTTVDSNAETALQANRLAMSASDAAERGGQAVSDVVATMREITDSSRKIA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAQRSAHAAKEIKTLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
ASVERVESGARRVDEAGRTMEDIVAQVKRVSDLIAAISASTAEQSTGVAQVDQAVVHLDT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHH
ITQQNAALVEQSAAASASLKQQAARLVDAIEVFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]