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The map label for this gene is mocR [H]

Identifier: 189353909

GI number: 189353909

Start: 2219840

End: 2221351

Strand: Reverse

Name: mocR [H]

Synonym: BMULJ_05161

Alternate gene names: 189353909

Gene position: 2221351-2219840 (Counterclockwise)

Preceding gene: 189353912

Following gene: 189353907

Centisome position: 89.82

GC content: 71.16

Gene sequence:

>1512_bases
ATGCGCGCAAGCGTGTTGTCGGACTGGCTTGCGCAGCGCCTCGTGCGCGGCGGCGAGCAGCCGATCTACCGGCAGCTGCA
TCGGCTGCTGCAGCAGGCGATCCTGTCGCGCGAACTGCCGGCCGGCGCGCGCGTGCCGTCGTCGCGGCTGCTCGCGGCCG
AGCTCGGGATCGCGCGCAACACGGTCACGCAGGTGTACGAGCAGCTCGCGCTCGAAGGCTATGTGCATTCGGCGACCGGC
CGCGGCACGTTCGTCGCCGACAGCGCGCCCGACGAGATCGTCGGCGCGCCGCCGGAGACGGGCGCGCGGCATGCGGCCGT
GCAGCCGTCGGCGCGCGCGTTGTCGGCGCGCGGCACGCGGCTCGTCGAAGGCGCCGGCGTGTCGAAGCGGCAGGGCGGCG
CGTTCATGCCGGGCGTGCCCGATGTGTCGCGATTTCCGGCGCGCGTGTGGACGCGGCTGCACAACAAGTACTGGCGGCGG
CTGCGCCCCGATCTCCTGACTTACGCGCCGGGCGGCGGGCTCGCGCTGCTGCGCGAGGCGCTGGCCGACTATCTGCGCAC
GTCGCGCTCGGTGCGCTGCACGCCCGAGCAGATCGTGATCACGACCGGCATCCACCAGTCGATCGACCTGGCGGTGCGGC
TGCTGACCGATCCCGGCGACGCAATCTGGACCGAGGACCCGTGCTATTGGGGCGTGCGCAGCGTGCTGAACGTGTCGGGG
CTCACGACGCGGCCGATTCCGGTCGACGACGAAGGGATCGCGCCGAGCGCCGCCGATCTCGCCGAGCCGCCGAAGCTGAT
GCTCGTCACGCCGTCGCATCAGTATCCGCTCGGCATGGTGATGAGCCTCGCGCGGCGGCGGATGCTGCTCGAATATGCGC
GCCAGCACGGCTGCTGGATCATCGAGGACGACTACGACAGCGAGTTCCGCTACGGCAGCCGGCCGCTCGCGTCGCTGCAG
GGCCTCGATACGGCCGGGCAGGTGATCTACGTCGGCAGCTTCGGCAAGACGCTGTTTCCGGGCCTGCGCGTCGGCTATCT
GGTGGCGCCGGAGCCGCTCGCGGAAAGCTTCGCGACCGCGAGCGCCGAGCTCTATCGCGAAGGTCAGCTGCTGCAGCAGG
CGGTGCTCGCGGAGTTCATCGCCGAAGGGCATTTCGTGTCGCACATCCGCAAGATGCGCACGCTGTACGGCCAGCGCCGC
GAGGTGCTGCTCGACGCGGTCGCGCGCCGCTACGGCGACGCGCTGCAGGCGCTCGGCAGCGATGCGGGGCTGCATCTCGT
CACGCGGCTGCCGGACGGTGTCGACGATCGCGCGGTCGCGCAGGCCGCGCTCGAACGCAATATCGTCGTGCGGCCCTTGT
CCGGCTATTACGCGGATCGTGCACGCGCGTCGTCGGGACTGCTGCTCGGTTACGCGTGCGTGCCCGAAGACGAGATCGAG
ACGGCGTTCGCGACGCTTGCGGAAGCGATCGATGCGCGGGCCTTCGTTGGGCCCGACACCGCGGCCGCGTAG

Upstream 100 bases:

>100_bases
TGAGGTGAGAGGCGGGCGCATCGGCAACCCATGGTCGCGACTATAATCACATTTGGCTCTGGCAATCAGAGCCATTTCAA
TAAATAGTTAGGAGCCAATC

Downstream 100 bases:

>100_bases
CGGCGCGGCACGGACGTGCGCATGCACATGTAGGCGCAGGCGCGCGCTACAGCCGGATCAGCGCCGCGCCCGCGACGACG
AGCGCACACGCGACGAGCCG

Product: DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MRASVLSDWLAQRLVRGGEQPIYRQLHRLLQQAILSRELPAGARVPSSRLLAAELGIARNTVTQVYEQLALEGYVHSATG
RGTFVADSAPDEIVGAPPETGARHAAVQPSARALSARGTRLVEGAGVSKRQGGAFMPGVPDVSRFPARVWTRLHNKYWRR
LRPDLLTYAPGGGLALLREALADYLRTSRSVRCTPEQIVITTGIHQSIDLAVRLLTDPGDAIWTEDPCYWGVRSVLNVSG
LTTRPIPVDDEGIAPSAADLAEPPKLMLVTPSHQYPLGMVMSLARRRMLLEYARQHGCWIIEDDYDSEFRYGSRPLASLQ
GLDTAGQVIYVGSFGKTLFPGLRVGYLVAPEPLAESFATASAELYREGQLLQQAVLAEFIAEGHFVSHIRKMRTLYGQRR
EVLLDAVARRYGDALQALGSDAGLHLVTRLPDGVDDRAVAQAALERNIVVRPLSGYYADRARASSGLLLGYACVPEDEIE
TAFATLAEAIDARAFVGPDTAAA

Sequences:

>Translated_503_residues
MRASVLSDWLAQRLVRGGEQPIYRQLHRLLQQAILSRELPAGARVPSSRLLAAELGIARNTVTQVYEQLALEGYVHSATG
RGTFVADSAPDEIVGAPPETGARHAAVQPSARALSARGTRLVEGAGVSKRQGGAFMPGVPDVSRFPARVWTRLHNKYWRR
LRPDLLTYAPGGGLALLREALADYLRTSRSVRCTPEQIVITTGIHQSIDLAVRLLTDPGDAIWTEDPCYWGVRSVLNVSG
LTTRPIPVDDEGIAPSAADLAEPPKLMLVTPSHQYPLGMVMSLARRRMLLEYARQHGCWIIEDDYDSEFRYGSRPLASLQ
GLDTAGQVIYVGSFGKTLFPGLRVGYLVAPEPLAESFATASAELYREGQLLQQAVLAEFIAEGHFVSHIRKMRTLYGQRR
EVLLDAVARRYGDALQALGSDAGLHLVTRLPDGVDDRAVAQAALERNIVVRPLSGYYADRARASSGLLLGYACVPEDEIE
TAFATLAEAIDARAFVGPDTAAA
>Mature_503_residues
MRASVLSDWLAQRLVRGGEQPIYRQLHRLLQQAILSRELPAGARVPSSRLLAAELGIARNTVTQVYEQLALEGYVHSATG
RGTFVADSAPDEIVGAPPETGARHAAVQPSARALSARGTRLVEGAGVSKRQGGAFMPGVPDVSRFPARVWTRLHNKYWRR
LRPDLLTYAPGGGLALLREALADYLRTSRSVRCTPEQIVITTGIHQSIDLAVRLLTDPGDAIWTEDPCYWGVRSVLNVSG
LTTRPIPVDDEGIAPSAADLAEPPKLMLVTPSHQYPLGMVMSLARRRMLLEYARQHGCWIIEDDYDSEFRYGSRPLASLQ
GLDTAGQVIYVGSFGKTLFPGLRVGYLVAPEPLAESFATASAELYREGQLLQQAVLAEFIAEGHFVSHIRKMRTLYGQRR
EVLLDAVARRYGDALQALGSDAGLHLVTRLPDGVDDRAVAQAALERNIVVRPLSGYYADRARASSGLLLGYACVPEDEIE
TAFATLAEAIDARAFVGPDTAAA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=385, Percent_Identity=23.3766233766234, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI33469970, Length=385, Percent_Identity=23.3766233766234, Blast_Score=115, Evalue=7e-26,
Organism=Escherichia coli, GI1790797, Length=462, Percent_Identity=30.0865800865801, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1787710, Length=444, Percent_Identity=26.1261261261261, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321236, Length=280, Percent_Identity=22.8571428571429, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356535, Length=316, Percent_Identity=22.1518987341772, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54739; Mature: 54739

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASVLSDWLAQRLVRGGEQPIYRQLHRLLQQAILSRELPAGARVPSSRLLAAELGIARN
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
TVTQVYEQLALEGYVHSATGRGTFVADSAPDEIVGAPPETGARHAAVQPSARALSARGTR
HHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCE
LVEGAGVSKRQGGAFMPGVPDVSRFPARVWTRLHNKYWRRLRPDLLTYAPGGGLALLREA
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHH
LADYLRTSRSVRCTPEQIVITTGIHQSIDLAVRLLTDPGDAIWTEDPCYWGVRSVLNVSG
HHHHHHCCCCCCCCCCEEEEECCCCHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHCCC
LTTRPIPVDDEGIAPSAADLAEPPKLMLVTPSHQYPLGMVMSLARRRMLLEYARQHGCWI
CCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
IEDDYDSEFRYGSRPLASLQGLDTAGQVIYVGSFGKTLFPGLRVGYLVAPEPLAESFATA
EECCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCHHHCCCCCEEEEECCHHHHHHHHHH
SAELYREGQLLQQAVLAEFIAEGHFVSHIRKMRTLYGQRREVLLDAVARRYGDALQALGS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DAGLHLVTRLPDGVDDRAVAQAALERNIVVRPLSGYYADRARASSGLLLGYACVPEDEIE
CCCEEEEECCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCEEEEEECCCCHHHH
TAFATLAEAIDARAFVGPDTAAA
HHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRASVLSDWLAQRLVRGGEQPIYRQLHRLLQQAILSRELPAGARVPSSRLLAAELGIARN
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
TVTQVYEQLALEGYVHSATGRGTFVADSAPDEIVGAPPETGARHAAVQPSARALSARGTR
HHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCE
LVEGAGVSKRQGGAFMPGVPDVSRFPARVWTRLHNKYWRRLRPDLLTYAPGGGLALLREA
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHH
LADYLRTSRSVRCTPEQIVITTGIHQSIDLAVRLLTDPGDAIWTEDPCYWGVRSVLNVSG
HHHHHHCCCCCCCCCCEEEEECCCCHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHCCC
LTTRPIPVDDEGIAPSAADLAEPPKLMLVTPSHQYPLGMVMSLARRRMLLEYARQHGCWI
CCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
IEDDYDSEFRYGSRPLASLQGLDTAGQVIYVGSFGKTLFPGLRVGYLVAPEPLAESFATA
EECCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCHHHCCCCCEEEEECCHHHHHHHHHH
SAELYREGQLLQQAVLAEFIAEGHFVSHIRKMRTLYGQRREVLLDAVARRYGDALQALGS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DAGLHLVTRLPDGVDDRAVAQAALERNIVVRPLSGYYADRARASSGLLLGYACVPEDEIE
CCCEEEEECCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCEEEEEECCCCHHHH
TAFATLAEAIDARAFVGPDTAAA
HHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]