BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is fabG [H]

Identifier: 189353273

GI number: 189353273

Start: 1512209

End: 1513006

Strand: Reverse

Name: fabG [H]

Synonym: BMULJ_04513

Alternate gene names: 189353273

Gene position: 1513006-1512209 (Counterclockwise)

Preceding gene: 189353274

Following gene: 189353272

Centisome position: 61.18

GC content: 68.17

Gene sequence:

>798_bases
ATGATTCAGATCGATCTGACCGGGCAGGTCGCGGTGGTGACGGGCGGCTCGTCCGGCATCGGCCTCGCGACGGCCGAACG
GTTCTTGCAGGCCGGCGCGTCGGTCGCGATTTGCGGCCGCGACGGCGACCGTCTCACGCGCGCGGAGACGATGCTCGGCG
AACGGTATCCGGGCGCGCCGCTGCTCGCCGTGCGCTGCAACGTGCTCGACGAAGCCGACGTGAGCGCGTTCGCGCAGGCC
GTGTCGGACCGCTTCGGCCGCACCGACATGCTCGTCAACAACGCCGGCCAGGGCCGCGTGTCGACGTTTGCCGAGACGAC
CGACGAGGCGTGGCGCGACGAGCTCGAGCTCAAGTACTTCAGCATCATCCGCCCGACGCGCGCGTTCCTGCCGATGCTGC
GCGACGCGGCTGCGCCGACGATCACGTGCGTGAACTCGCTGCTCGCGCTGCAGCCGGAGCCGCACATGGTCGCGACCTCG
TCCGCGCGCGCCGGTGTGCTGAGCCTCGTGAAGTCGCTCGCGACGGAACTGGCGCCGCAGCGGATCCGCGTGAACTCGAT
CCTGATCGGGATCGTCGAGTCCGGCCAGTGGCGCCGCCGTTACGAGGCACAGGCACAGCCCGGCGAAAGCTGGGAAGACT
GGACCGGTGCGCTCGCGCGCAAGAAGAACATTCCGCTGAACCGCTTCGGCAAGCCCGACGAGGCCGCCTGGGCGCTTTTT
TATCTCGCAACGCATCTGTCGTCCTACACGACGGGCAGCCATATCGACGTTTCTGGAGGCTTTGCACGCCATGTCTAA

Upstream 100 bases:

>100_bases
GGCTGATCGACAAGGTGCGGCGCGCGGCGGCCGAACTGTCGCGGCGGCTCAATTACCGCTCGGACGACGAGCACACGTTT
TTGAAGGCTTTGGGACTCCG

Downstream 100 bases:

>100_bases
AAAAACCACGGTTGGCGAGCTGATTGCCGCCTTTCTCGAGCAGTGCGGCGTGAAGACCGCATTCGGTGTCATCTCGATCC
ACAACATGCCGATCCTCGAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MIQIDLTGQVAVVTGGSSGIGLATAERFLQAGASVAICGRDGDRLTRAETMLGERYPGAPLLAVRCNVLDEADVSAFAQA
VSDRFGRTDMLVNNAGQGRVSTFAETTDEAWRDELELKYFSIIRPTRAFLPMLRDAAAPTITCVNSLLALQPEPHMVATS
SARAGVLSLVKSLATELAPQRIRVNSILIGIVESGQWRRRYEAQAQPGESWEDWTGALARKKNIPLNRFGKPDEAAWALF
YLATHLSSYTTGSHIDVSGGFARHV

Sequences:

>Translated_265_residues
MIQIDLTGQVAVVTGGSSGIGLATAERFLQAGASVAICGRDGDRLTRAETMLGERYPGAPLLAVRCNVLDEADVSAFAQA
VSDRFGRTDMLVNNAGQGRVSTFAETTDEAWRDELELKYFSIIRPTRAFLPMLRDAAAPTITCVNSLLALQPEPHMVATS
SARAGVLSLVKSLATELAPQRIRVNSILIGIVESGQWRRRYEAQAQPGESWEDWTGALARKKNIPLNRFGKPDEAAWALF
YLATHLSSYTTGSHIDVSGGFARHV
>Mature_265_residues
MIQIDLTGQVAVVTGGSSGIGLATAERFLQAGASVAICGRDGDRLTRAETMLGERYPGAPLLAVRCNVLDEADVSAFAQA
VSDRFGRTDMLVNNAGQGRVSTFAETTDEAWRDELELKYFSIIRPTRAFLPMLRDAAAPTITCVNSLLALQPEPHMVATS
SARAGVLSLVKSLATELAPQRIRVNSILIGIVESGQWRRRYEAQAQPGESWEDWTGALARKKNIPLNRFGKPDEAAWALF
YLATHLSSYTTGSHIDVSGGFARHV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=30.8880308880309, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=28.0155642023346, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=28.8537549407115, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=26.9230769230769, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=29.1828793774319, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=30.5084745762712, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=29.5719844357977, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI66933014, Length=261, Percent_Identity=28.735632183908, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=28.0612244897959, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=29.8969072164948, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=28.4090909090909, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=29.3478260869565, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=31.413612565445, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=27.4725274725275, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=27.8350515463918, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI109715829, Length=256, Percent_Identity=26.171875, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=26.3940520446097, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=29.4573643410853, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=30.3501945525292, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=27.734375, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789378, Length=261, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=28.7878787878788, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=25.968992248062, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367175, Length=258, Percent_Identity=29.8449612403101, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788459, Length=264, Percent_Identity=28.030303030303, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=23.828125, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=24.7104247104247, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082160, Length=269, Percent_Identity=26.3940520446097, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=29.9610894941634, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=30.9433962264151, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=28.1853281853282, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=28.740157480315, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=31.1787072243346, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=29.2490118577075, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=30.3030303030303, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=28.1368821292776, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=30.1960784313725, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=29.3436293436293, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.5171102661597, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=29.0566037735849, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=27.8625954198473, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=29.7397769516729, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=27.2373540856031, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=29.6577946768061, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=28.030303030303, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=28.1954887218045, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=27.7566539923954, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=27.9245283018868, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=27.8195488721804, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=26.7924528301887, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=27.8195488721804, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=25.3731343283582, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=25, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=175, Percent_Identity=29.1428571428571, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=261, Percent_Identity=29.5019157088123, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=266, Percent_Identity=25.187969924812, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=26.8482490272374, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323882, Length=222, Percent_Identity=25.2252252252252, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=30.6513409961686, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=31.3953488372093, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=31.3953488372093, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=28.4046692607004, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=29.0076335877863, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=29.8449612403101, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644337, Length=263, Percent_Identity=30.7984790874525, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17737361, Length=266, Percent_Identity=29.3233082706767, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639444, Length=266, Percent_Identity=27.8195488721804, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28677; Mature: 28677

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQIDLTGQVAVVTGGSSGIGLATAERFLQAGASVAICGRDGDRLTRAETMLGERYPGAP
CEEEEECCEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCC
LLAVRCNVLDEADVSAFAQAVSDRFGRTDMLVNNAGQGRVSTFAETTDEAWRDELELKYF
EEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
SIIRPTRAFLPMLRDAAAPTITCVNSLLALQPEPHMVATSSARAGVLSLVKSLATELAPQ
HHHCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
RIRVNSILIGIVESGQWRRRYEAQAQPGESWEDWTGALARKKNIPLNRFGKPDEAAWALF
CEEEEEEEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
YLATHLSSYTTGSHIDVSGGFARHV
HHHHHHHHCCCCCEEECCCCHHCCC
>Mature Secondary Structure
MIQIDLTGQVAVVTGGSSGIGLATAERFLQAGASVAICGRDGDRLTRAETMLGERYPGAP
CEEEEECCEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCC
LLAVRCNVLDEADVSAFAQAVSDRFGRTDMLVNNAGQGRVSTFAETTDEAWRDELELKYF
EEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
SIIRPTRAFLPMLRDAAAPTITCVNSLLALQPEPHMVATSSARAGVLSLVKSLATELAPQ
HHHCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
RIRVNSILIGIVESGQWRRRYEAQAQPGESWEDWTGALARKKNIPLNRFGKPDEAAWALF
CEEEEEEEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
YLATHLSSYTTGSHIDVSGGFARHV
HHHHHHHHCCCCCEEECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]