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The map label for this gene is cusR [H]

Identifier: 189352957

GI number: 189352957

Start: 1112678

End: 1113376

Strand: Reverse

Name: cusR [H]

Synonym: BMULJ_04191

Alternate gene names: 189352957

Gene position: 1113376-1112678 (Counterclockwise)

Preceding gene: 189352958

Following gene: 189352956

Centisome position: 45.02

GC content: 65.95

Gene sequence:

>699_bases
ATGAAAGTACTGATCATCGAAGACGAACCGAAAGTCGTCGAATATCTGAAGAGCGGACTGACCGAGGAAGGCTGGGTCGT
CGATACCGCGCTCGACGGCGAGGACGGTGCATGGAAGGCGGTCGAGTTCGACTACGACGTGGTCGTGCTCGACGTGATGC
TGCCGAAGCTCGACGGCTTCGGCGTGCTGCGCGCCTTGCGCGCGCAGAAGCAGACGCCCGTCATCATGCTGACTGCGCGC
GACCGCGTCGACGATCGCGTGCGCGGGCTGCGCGGCGGCGCCGACGACTATCTGACCAAGCCGTTCTCGTTCCTCGAACT
GATCGAGCGGCTGCGCGCATTGACGCGTCGCGCGCGCGTGCAGGAATCGACGCTGATCTCGATCGGCGACCTGCGTGTCG
ACCTGATCGGCCGCCGCGCGACGCGCGACGGCACGCGGCTCGATCTGACCGCGCAGGAATTCCAGCTGCTCGGCGTGCTC
GCGCGGCGCAGCGGCGAGGTGCTGTCGAAGACGACGATCGCCGAGCTCGTCTGGGACGTGAATTTCGACAGCAACGCGAA
CGTCGTCGAAACCGCGATCAAGCGGCTGCGCGCGAAGCTCGACGGCCCGTTCCCGGAGAAGCTGCTGCATACGATTCGCG
GCATGGGCTACGTGCTCGAAGCGCGCGACGACGGCGGCGACACGGAGAAGCGCACATGA

Upstream 100 bases:

>100_bases
GCGGCGGCTGGAACGGCGCGGCCCCGACCTCCTCCGACATGGCGGCCGCGGACGCCGCCGGCACGCGCCCGTCGGCGGTC
ACGCGATAACGGATCCGAAC

Downstream 100 bases:

>100_bases
AACGCTCGATCGCGCTGCGGCTGTCGACGATGTTCGGCATCGTGTCGCTGCTCGTCTTTACGCTCGTCGGCTGCGGGCTG
TTCGTGATGATGGAGCGCCA

Product: two-component system copper resistance phosphate regulon response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKVLIIEDEPKVVEYLKSGLTEEGWVVDTALDGEDGAWKAVEFDYDVVVLDVMLPKLDGFGVLRALRAQKQTPVIMLTAR
DRVDDRVRGLRGGADDYLTKPFSFLELIERLRALTRRARVQESTLISIGDLRVDLIGRRATRDGTRLDLTAQEFQLLGVL
ARRSGEVLSKTTIAELVWDVNFDSNANVVETAIKRLRAKLDGPFPEKLLHTIRGMGYVLEARDDGGDTEKRT

Sequences:

>Translated_232_residues
MKVLIIEDEPKVVEYLKSGLTEEGWVVDTALDGEDGAWKAVEFDYDVVVLDVMLPKLDGFGVLRALRAQKQTPVIMLTAR
DRVDDRVRGLRGGADDYLTKPFSFLELIERLRALTRRARVQESTLISIGDLRVDLIGRRATRDGTRLDLTAQEFQLLGVL
ARRSGEVLSKTTIAELVWDVNFDSNANVVETAIKRLRAKLDGPFPEKLLHTIRGMGYVLEARDDGGDTEKRT
>Mature_232_residues
MKVLIIEDEPKVVEYLKSGLTEEGWVVDTALDGEDGAWKAVEFDYDVVVLDVMLPKLDGFGVLRALRAQKQTPVIMLTAR
DRVDDRVRGLRGGADDYLTKPFSFLELIERLRALTRRARVQESTLISIGDLRVDLIGRRATRDGTRLDLTAQEFQLLGVL
ARRSGEVLSKTTIAELVWDVNFDSNANVVETAIKRLRAKLDGPFPEKLLHTIRGMGYVLEARDDGGDTEKRT

Specific function: Member of the two-component regulatory system CzcS/CzcR involved in the control of cobalt, zinc and cadmium homeostasis [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=53.393665158371, Blast_Score=242, Evalue=2e-65,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=50.6666666666667, Blast_Score=223, Evalue=8e-60,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=40.4545454545455, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.4821428571429, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=33.6283185840708, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.2608695652174, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=32.5991189427313, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=35.6164383561644, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=38.4615384615385, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=32.8888888888889, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=32.4444444444444, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=30.8695652173913, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=30.2631578947368, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=27.8260869565217, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=34.5794392523364, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788713, Length=121, Percent_Identity=33.8842975206612, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26055; Mature: 26055

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIIEDEPKVVEYLKSGLTEEGWVVDTALDGEDGAWKAVEFDYDVVVLDVMLPKLDGF
CEEEEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEECCCCEEEEEEHHCCCCCH
GVLRALRAQKQTPVIMLTARDRVDDRVRGLRGGADDYLTKPFSFLELIERLRALTRRARV
HHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
QESTLISIGDLRVDLIGRRATRDGTRLDLTAQEFQLLGVLARRSGEVLSKTTIAELVWDV
HHHHEEEECCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEC
NFDSNANVVETAIKRLRAKLDGPFPEKLLHTIRGMGYVLEARDDGGDTEKRT
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKVLIIEDEPKVVEYLKSGLTEEGWVVDTALDGEDGAWKAVEFDYDVVVLDVMLPKLDGF
CEEEEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEECCCCEEEEEEHHCCCCCH
GVLRALRAQKQTPVIMLTARDRVDDRVRGLRGGADDYLTKPFSFLELIERLRALTRRARV
HHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
QESTLISIGDLRVDLIGRRATRDGTRLDLTAQEFQLLGVLARRSGEVLSKTTIAELVWDV
HHHHEEEECCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEC
NFDSNANVVETAIKRLRAKLDGPFPEKLLHTIRGMGYVLEARDDGGDTEKRT
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9044283 [H]