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The map label for this gene is tctE [H]

Identifier: 189352930

GI number: 189352930

Start: 1082869

End: 1084299

Strand: Direct

Name: tctE [H]

Synonym: BMULJ_04164

Alternate gene names: 189352930

Gene position: 1082869-1084299 (Clockwise)

Preceding gene: 189352929

Following gene: 189352939

Centisome position: 43.78

GC content: 70.16

Gene sequence:

>1431_bases
GTGAAGCAGCCGAACCTGCGGGCGCAGGTCGCGCTGTGGTTGCTGCTGCCGCTGCTCGGCCTGCTCGCCTTCGATTCCTG
GCTCACCTACCAGCGCGCGATGAGCGCCGCACACGTCGCGTTCGATCGCACGTTGTCGTCGTCGCTGAAGTCGATCCGCG
AAGGCGTGCGGCTCAATGACGGCGACATCGAGGTCGACCTGCCGTATCTCGCACTCGAGATGTTCGAATCCGGCGACGGC
GGCAAGATCTACTACCTGATCCGCGAGGACAACGGCCGCACGATCACGGGCTATCCCGACCTGCCGCTGCCGCCCGGCGA
CGACGCGGCCGCGGCCGGCGATCGTACGCTGTTCGTCACGCACTACTACGACGTCGTCTATCGCGGCGAGCAGCTGCGCA
TGGCCGCGCTGCGCGTGCCGGTGCACGACGTGCCGACCGCGCAGACGCGCATCGTCTGGGTGATGGTCGGCGAGACGATC
GAGGCGCGCCAGGCGCTGGCGCGGCAGATTCTCGTCGGCTCGCTGCTGCAGGAAGGGTTGCTCGTCGTGCTCGCGCTCGG
CATCGTATGGCTCGGCGTCGGGCGCGGGCTGCGGCCGCTGAACCGGCTCTCGGCGACGGTCGCCGCGCGCAGCGAGGACG
ACCCGACGCCGCTCGATACGGGCGGGATGCCGAGCGAACTCGCGCCGCTCGTCGAGTCGATCAACCAGTACATCGGTCGC
ACGCAGCGGATGCAGGTCGCGCGGCGGCGCTTCTTCGCGGACGCCGCGCATCAGCTGAAGACGCCGCTCGCGGCCGTGCA
GGCCGGCGTCGAACTCGCGCTGCGTCCCGACGAGCAGCCGCGCGTGAACGTGCATCTGCGTCGCGTGAACGGCGCGGTGC
GGCAGGCCGCGAAGATCGTCCAGCAATTGCTATCGTTGTCGCGGCTCGATTCGGACAGCGGCCATGCGGCCGCGCACAAG
ACGGTCGCGCTGCATCGGCTCGCGCGCAGCGTGACGCTCGACTGGTCGCCGGTCGCGCGCGCACGCGACATCGATCTCGG
CTTCGAGCACGATGCCGACGTCACGGTGCACGGCCAGCCCGATCTGCTCGGCGAGATGATCGGCAACCTGATCGACAACG
CGATCCGCTATGCGGGCGACCGCGCGGTGATCACGGTGCGCGTGTCGCGCGAGGGCGAGTGCGCGCGGCTCGACGTGATC
GACAACGGGCCCGGTATTCCCGAAGACGAGCGCGAGGCGGTGTTCGAGCGCTTCCATCGCGGCAGCACGACGCAGACGGT
GGAAGGCACGGGGCTCGGGTTGTCGATCGTGCGCGAGATTGCGCGCGTGCATCGGGGCAGTGTGGTGCTAGCCCCTGCAG
CGGGCGGCGGCTTGATCGTGACGGTGCGCTTGCCGGCGGCGGCGGACGCCGCCGCGTCGCGCGTGCGCTGA

Upstream 100 bases:

>100_bases
AGATCTACGTGTACCGGCTGCGCAAGAAGCTCGAGAACAGCGGCGTCGCGATCGTCACGCTGCGCGGGCTCGGCTATCTG
CTCGAAGCGAAGGCCGACGC

Downstream 100 bases:

>100_bases
GCTTGATTAAATTTAATCGCCGAAGCCGATCTCCGCATCGAGCGGCTGGCCGACCTCGAGCCACGCACCGGCGCCTTCGA
CGACGATCGCATTGATGCCG

Product: OmpR family two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MKQPNLRAQVALWLLLPLLGLLAFDSWLTYQRAMSAAHVAFDRTLSSSLKSIREGVRLNDGDIEVDLPYLALEMFESGDG
GKIYYLIREDNGRTITGYPDLPLPPGDDAAAAGDRTLFVTHYYDVVYRGEQLRMAALRVPVHDVPTAQTRIVWVMVGETI
EARQALARQILVGSLLQEGLLVVLALGIVWLGVGRGLRPLNRLSATVAARSEDDPTPLDTGGMPSELAPLVESINQYIGR
TQRMQVARRRFFADAAHQLKTPLAAVQAGVELALRPDEQPRVNVHLRRVNGAVRQAAKIVQQLLSLSRLDSDSGHAAAHK
TVALHRLARSVTLDWSPVARARDIDLGFEHDADVTVHGQPDLLGEMIGNLIDNAIRYAGDRAVITVRVSREGECARLDVI
DNGPGIPEDEREAVFERFHRGSTTQTVEGTGLGLSIVREIARVHRGSVVLAPAAGGGLIVTVRLPAAADAAASRVR

Sequences:

>Translated_476_residues
MKQPNLRAQVALWLLLPLLGLLAFDSWLTYQRAMSAAHVAFDRTLSSSLKSIREGVRLNDGDIEVDLPYLALEMFESGDG
GKIYYLIREDNGRTITGYPDLPLPPGDDAAAAGDRTLFVTHYYDVVYRGEQLRMAALRVPVHDVPTAQTRIVWVMVGETI
EARQALARQILVGSLLQEGLLVVLALGIVWLGVGRGLRPLNRLSATVAARSEDDPTPLDTGGMPSELAPLVESINQYIGR
TQRMQVARRRFFADAAHQLKTPLAAVQAGVELALRPDEQPRVNVHLRRVNGAVRQAAKIVQQLLSLSRLDSDSGHAAAHK
TVALHRLARSVTLDWSPVARARDIDLGFEHDADVTVHGQPDLLGEMIGNLIDNAIRYAGDRAVITVRVSREGECARLDVI
DNGPGIPEDEREAVFERFHRGSTTQTVEGTGLGLSIVREIARVHRGSVVLAPAAGGGLIVTVRLPAAADAAASRVR
>Mature_476_residues
MKQPNLRAQVALWLLLPLLGLLAFDSWLTYQRAMSAAHVAFDRTLSSSLKSIREGVRLNDGDIEVDLPYLALEMFESGDG
GKIYYLIREDNGRTITGYPDLPLPPGDDAAAAGDRTLFVTHYYDVVYRGEQLRMAALRVPVHDVPTAQTRIVWVMVGETI
EARQALARQILVGSLLQEGLLVVLALGIVWLGVGRGLRPLNRLSATVAARSEDDPTPLDTGGMPSELAPLVESINQYIGR
TQRMQVARRRFFADAAHQLKTPLAAVQAGVELALRPDEQPRVNVHLRRVNGAVRQAAKIVQQLLSLSRLDSDSGHAAAHK
TVALHRLARSVTLDWSPVARARDIDLGFEHDADVTVHGQPDLLGEMIGNLIDNAIRYAGDRAVITVRVSREGECARLDVI
DNGPGIPEDEREAVFERFHRGSTTQTVEGTGLGLSIVREIARVHRGSVVLAPAAGGGLIVTVRLPAAADAAASRVR

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=317, Percent_Identity=37.2239747634069, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI87082128, Length=256, Percent_Identity=30.859375, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=30.0724637681159, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790861, Length=306, Percent_Identity=30.0653594771242, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790551, Length=298, Percent_Identity=31.5436241610738, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=250, Percent_Identity=29.6, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788279, Length=355, Percent_Identity=24.7887323943662, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786783, Length=299, Percent_Identity=29.0969899665552, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=30.7017543859649, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790346, Length=247, Percent_Identity=27.9352226720648, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1787374, Length=277, Percent_Identity=25.6317689530686, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=25.8741258741259, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI145693157, Length=239, Percent_Identity=26.3598326359833, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=29.7777777777778, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=21.3438735177866, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=218, Percent_Identity=25.6880733944954, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=271, Percent_Identity=23.9852398523985, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51793; Mature: 51793

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQPNLRAQVALWLLLPLLGLLAFDSWLTYQRAMSAAHVAFDRTLSSSLKSIREGVRLND
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GDIEVDLPYLALEMFESGDGGKIYYLIREDNGRTITGYPDLPLPPGDDAAAAGDRTLFVT
CCEEEECHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCEEEEE
HYYDVVYRGEQLRMAALRVPVHDVPTAQTRIVWVMVGETIEARQALARQILVGSLLQEGL
EEEEHHCCCCHHEEHHEECCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
LVVLALGIVWLGVGRGLRPLNRLSATVAARSEDDPTPLDTGGMPSELAPLVESINQYIGR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCH
TQRMQVARRRFFADAAHQLKTPLAAVQAGVELALRPDEQPRVNVHLRRVNGAVRQAAKIV
HHHHHHHHHHHHHHHHHHHHCHHHHHHHCCEEEECCCCCCCEEEEEEHHHHHHHHHHHHH
QQLLSLSRLDSDSGHAAAHKTVALHRLARSVTLDWSPVARARDIDLGFEHDADVTVHGQP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCH
DLLGEMIGNLIDNAIRYAGDRAVITVRVSREGECARLDVIDNGPGIPEDEREAVFERFHR
HHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHC
GSTTQTVEGTGLGLSIVREIARVHRGSVVLAPAAGGGLIVTVRLPAAADAAASRVR
CCCCCEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHCCC
>Mature Secondary Structure
MKQPNLRAQVALWLLLPLLGLLAFDSWLTYQRAMSAAHVAFDRTLSSSLKSIREGVRLND
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GDIEVDLPYLALEMFESGDGGKIYYLIREDNGRTITGYPDLPLPPGDDAAAAGDRTLFVT
CCEEEECHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCEEEEE
HYYDVVYRGEQLRMAALRVPVHDVPTAQTRIVWVMVGETIEARQALARQILVGSLLQEGL
EEEEHHCCCCHHEEHHEECCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
LVVLALGIVWLGVGRGLRPLNRLSATVAARSEDDPTPLDTGGMPSELAPLVESINQYIGR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCH
TQRMQVARRRFFADAAHQLKTPLAAVQAGVELALRPDEQPRVNVHLRRVNGAVRQAAKIV
HHHHHHHHHHHHHHHHHHHHCHHHHHHHCCEEEECCCCCCCEEEEEEHHHHHHHHHHHHH
QQLLSLSRLDSDSGHAAAHKTVALHRLARSVTLDWSPVARARDIDLGFEHDADVTVHGQP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCH
DLLGEMIGNLIDNAIRYAGDRAVITVRVSREGECARLDVIDNGPGIPEDEREAVFERFHR
HHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHC
GSTTQTVEGTGLGLSIVREIARVHRGSVVLAPAAGGGLIVTVRLPAAADAAASRVR
CCCCCEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]