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The map label for this gene is bcd [H]

Identifier: 189352939

GI number: 189352939

Start: 1092796

End: 1094118

Strand: Direct

Name: bcd [H]

Synonym: BMULJ_04173

Alternate gene names: 189352939

Gene position: 1092796-1094118 (Clockwise)

Preceding gene: 189352930

Following gene: 189352941

Centisome position: 44.19

GC content: 73.39

Gene sequence:

>1323_bases
ATGTCCGCCAGCCTTGCTGCTTCGCTGCCGTCGCGCGAGTCGTCGCTGCGCCGCCTGCCCGACGACGAGGCGCGCCTCGC
CGCGCTGCTCGACCGTCTCGTTCCCGAACTCGCGGCCGACGCCGTGCGCAACGATGTCGACGGCCGTTTTCCGCACGAGA
ATCTCGCGCGGCTGCAGCGCGCGGGGCTGATCGCGCAGGTCGTGCCGCGCGAGTTTGGCGGTGCCGGCGCGACGCTCGCG
CGCGCGAGCCGGATCGTCGCGGCCGTCGCACGCGCCGACCCCGCCACCGCGCTCGTGCTGACGATGACGTATCTGCAGCA
CCGTGCGCTCGGCCGGCCCGACAACCGCTGGCCCGCGCACGTGCGGCGCGCCGTGTTCGACAGCGCGGTCGCCGACGGCG
CGCTGATCAACGCGCTGCGCGTCGAGCCGGCGCTCGGTTCGCCGTCGCGCGGCGGGCTGCCCGACACGATTGCGCGTCGC
GACGGCGACGGCTGGCGGCTGTCCGGTCACAAGCTCTACAGCACCGGCATTCCGGCGCTGCGCTGGCTGGCCGTGTGGGC
GCGCACCGACGAGCCGCAGCCGCGTGTCGGCGTGTTCCTCGTTGCGCGCGATCCTCACGTGGACGACGCGCGGATCCGCG
TGATCGAAAGCTGGGATCATCTCGGCCTGCGCGCGTCCGGCAGCCACGAGGTCGTGTTCGACGACGTGCCGCTGCGCGCC
GATCATGCGGTCGACGTGCGTACGCCCGACGCGTGGTCGGTGTCGGCGGCCAGTCATGCGGACGTCGACGCGCAAGCCGA
CCAGCAGGCATGGATGGTCGCGCTGCTCGGCAGTCTCTACGACGCGGTCGCGCGGGCCGCGCACCACTGGCTGCTCGCGT
TCGCGACGACGCGCACGCCGACCGGCGTCGGCGCGCCGCTCGCGACGCTACCGCGCGTGCAGGAGGCCGTCGGCGAGATC
GAGGGCTGGCTGCATGCGAACCGTGTGCTGCTCGACGATCACGTTGCGCGTACCGATGCGGGCAATGCGCCGGCCGTGAC
GACGAGCGGACTCGTGAAGCGCACGGTGACGGAGCAGGCGATCCGCGCGGTCGAACAGGCGCTGAAGCTGTCCGGCAATC
ACGGGTTGAGCCGCCGCAATCCGCTCGAACGCCACTATCGCGACGTGCTGTGCAGCCGCGTGCATACGCCGCAGGACGAC
GCGATCGCGGTCGCGGCCGGACGCGCGGCGCTCGACGCGGCGGCGCGACGCACAGCAGGCGAGGGCGCTGGCGCGGGCCG
GACAACGCCTCGCGCATCGGCATCGGGCCGCTCCGATGCGTGA

Upstream 100 bases:

>100_bases
ACGCAGGCACCGCGTCCGTTCAAGGGCGGCGTCGCCGCCGGTATTGCCGGCGTACGCCGCCGCTTCGTCCCATGTCCCGT
TATCGAGAGAACCCGTACCG

Downstream 100 bases:

>100_bases
GCCTCGGGCGAGACCACGTCTCACGCGCGAGTATCGGGCCGACGCCATGCGTGAGCGTCGGGCGACACGACGTCTCACGC
GCCAGCGTTGGGCCGACGCG

Product: butyryl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSASLAASLPSRESSLRRLPDDEARLAALLDRLVPELAADAVRNDVDGRFPHENLARLQRAGLIAQVVPREFGGAGATLA
RASRIVAAVARADPATALVLTMTYLQHRALGRPDNRWPAHVRRAVFDSAVADGALINALRVEPALGSPSRGGLPDTIARR
DGDGWRLSGHKLYSTGIPALRWLAVWARTDEPQPRVGVFLVARDPHVDDARIRVIESWDHLGLRASGSHEVVFDDVPLRA
DHAVDVRTPDAWSVSAASHADVDAQADQQAWMVALLGSLYDAVARAAHHWLLAFATTRTPTGVGAPLATLPRVQEAVGEI
EGWLHANRVLLDDHVARTDAGNAPAVTTSGLVKRTVTEQAIRAVEQALKLSGNHGLSRRNPLERHYRDVLCSRVHTPQDD
AIAVAAGRAALDAAARRTAGEGAGAGRTTPRASASGRSDA

Sequences:

>Translated_440_residues
MSASLAASLPSRESSLRRLPDDEARLAALLDRLVPELAADAVRNDVDGRFPHENLARLQRAGLIAQVVPREFGGAGATLA
RASRIVAAVARADPATALVLTMTYLQHRALGRPDNRWPAHVRRAVFDSAVADGALINALRVEPALGSPSRGGLPDTIARR
DGDGWRLSGHKLYSTGIPALRWLAVWARTDEPQPRVGVFLVARDPHVDDARIRVIESWDHLGLRASGSHEVVFDDVPLRA
DHAVDVRTPDAWSVSAASHADVDAQADQQAWMVALLGSLYDAVARAAHHWLLAFATTRTPTGVGAPLATLPRVQEAVGEI
EGWLHANRVLLDDHVARTDAGNAPAVTTSGLVKRTVTEQAIRAVEQALKLSGNHGLSRRNPLERHYRDVLCSRVHTPQDD
AIAVAAGRAALDAAARRTAGEGAGAGRTTPRASASGRSDA
>Mature_439_residues
SASLAASLPSRESSLRRLPDDEARLAALLDRLVPELAADAVRNDVDGRFPHENLARLQRAGLIAQVVPREFGGAGATLAR
ASRIVAAVARADPATALVLTMTYLQHRALGRPDNRWPAHVRRAVFDSAVADGALINALRVEPALGSPSRGGLPDTIARRD
GDGWRLSGHKLYSTGIPALRWLAVWARTDEPQPRVGVFLVARDPHVDDARIRVIESWDHLGLRASGSHEVVFDDVPLRAD
HAVDVRTPDAWSVSAASHADVDAQADQQAWMVALLGSLYDAVARAAHHWLLAFATTRTPTGVGAPLATLPRVQEAVGEIE
GWLHANRVLLDDHVARTDAGNAPAVTTSGLVKRTVTEQAIRAVEQALKLSGNHGLSRRNPLERHYRDVLCSRVHTPQDDA
IAVAAGRAALDAAARRTAGEGAGAGRTTPRASASGRSDA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=24.4623655913978, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 46994; Mature: 46863

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASLAASLPSRESSLRRLPDDEARLAALLDRLVPELAADAVRNDVDGRFPHENLARLQR
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AGLIAQVVPREFGGAGATLARASRIVAAVARADPATALVLTMTYLQHRALGRPDNRWPAH
HCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
VRRAVFDSAVADGALINALRVEPALGSPSRGGLPDTIARRDGDGWRLSGHKLYSTGIPAL
HHHHHHHHHHHCCHHHHHHEECCCCCCCCCCCCCHHHHHCCCCCEEECCCEEECCCCHHH
RWLAVWARTDEPQPRVGVFLVARDPHVDDARIRVIESWDHLGLRASGSHEVVFDDVPLRA
HHHHHHHCCCCCCCCEEEEEEECCCCCCCHHEEEEECCCCCCCCCCCCCCEEEECCCCCC
DHAVDVRTPDAWSVSAASHADVDAQADQQAWMVALLGSLYDAVARAAHHWLLAFATTRTP
CCEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
TGVGAPLATLPRVQEAVGEIEGWLHANRVLLDDHVARTDAGNAPAVTTSGLVKRTVTEQA
CCCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCHHHHCCCCCCCCCCHHHHHHHHHHHHH
IRAVEQALKLSGNHGLSRRNPLERHYRDVLCSRVHTPQDDAIAVAAGRAALDAAARRTAG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHCCC
EGAGAGRTTPRASASGRSDA
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SASLAASLPSRESSLRRLPDDEARLAALLDRLVPELAADAVRNDVDGRFPHENLARLQR
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AGLIAQVVPREFGGAGATLARASRIVAAVARADPATALVLTMTYLQHRALGRPDNRWPAH
HCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
VRRAVFDSAVADGALINALRVEPALGSPSRGGLPDTIARRDGDGWRLSGHKLYSTGIPAL
HHHHHHHHHHHCCHHHHHHEECCCCCCCCCCCCCHHHHHCCCCCEEECCCEEECCCCHHH
RWLAVWARTDEPQPRVGVFLVARDPHVDDARIRVIESWDHLGLRASGSHEVVFDDVPLRA
HHHHHHHCCCCCCCCEEEEEEECCCCCCCHHEEEEECCCCCCCCCCCCCCEEEECCCCCC
DHAVDVRTPDAWSVSAASHADVDAQADQQAWMVALLGSLYDAVARAAHHWLLAFATTRTP
CCEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
TGVGAPLATLPRVQEAVGEIEGWLHANRVLLDDHVARTDAGNAPAVTTSGLVKRTVTEQA
CCCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCHHHHCCCCCCCCCCHHHHHHHHHHHHH
IRAVEQALKLSGNHGLSRRNPLERHYRDVLCSRVHTPQDDAIAVAAGRAALDAAARRTAG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHCCC
EGAGAGRTTPRASASGRSDA
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]