Click here to switch to the map view.

The map label for this gene is thcR [H]

Identifier: 189352230

GI number: 189352230

Start: 270344

End: 271318

Strand: Reverse

Name: thcR [H]

Synonym: BMULJ_03448

Alternate gene names: 189352230

Gene position: 271318-270344 (Counterclockwise)

Preceding gene: 189352233

Following gene: 189352229

Centisome position: 10.97

GC content: 71.69

Gene sequence:

>975_bases
ATGGACATCGCCCTTTCTGGACACGCACCGAACCGGCTCGGCGCGCTGCATGCGCCCGACGAAGTCGAACGCGCGGTCGC
GCACCGGCTCGGCCCGCACCGGATGGCCGCACACGGTCGCGATCCGTTTCATGCGGAGCTGTACGAGGTGCCGCTGCATC
ATGGCGCGCTGCTCGAGCTCTGCTACGGCCGCGAGACGCGCATCGACTTCGGCGACGATGCCGATCACTTCCTGTTCCGG
CTGACGTTGTCGGGCAGCTGCGAACTGCAGGCGGGACAAGCGATCGTGCATGCGGGCCCCGGCGAACTGACCGTGTCGTC
GCCAGCGCGCGCGAGCCGGCTGCGCACGAGCCGCGATTGCCGCAACCTCGTGCTGCGGCTCGAACGCCGCGCGCTCGAAC
GCAAGCTGCAGGACATGCTCGGCACGACGCTCGCGCGGCCGCTGCAGTTCGAAGTCGATGCGAGCCGCCACCGCGCCGGT
GCCGCGCTCGTGCTGCCCACCTTCGACTATCTGTGCCGGCTCGGTACGCAGCCCGCACTCGGCGCGGCCGCCGCGACGTT
CGGCGCGGATCTCAGCGCGTGGCTGATGTCGCTGCTGCTCACGCATCTGCCGCATTCGTACAGCGACGCGCTCGCGCGCG
GCACGCCTCCGCTGCCCGCGCCGGTGCGCCGCGCATGCGCGTACGTCGACGCGCATCTCGGCGAGCCGCTCGCGCTCGCG
GCCCTGGCGCGCGTCGCGGGCGTCGCGCCGCGCACGCTGCAGCACGCGTTTCGCACCTTCCTGAACACCACGCCGGCCGC
GTACGTGCGCGACCGCCGGCTCGCCGCCGTGCACGCGGCGCTGCAACGCGGCGACGCGCGCAGCGTGACCGACGTGCTGC
TCGCGCACGGCATTCACGGTTTCGGTCATTTCGCGAAGGCGTATGCACGGCGTTACGGCCATCCGCCTTCCGTCACTGCG
AGGCAACCGCGATGA

Upstream 100 bases:

>100_bases
CGTCGCTTCAAAACGCGCAACGGCGCGCCCGATCGCGCAACGCAATCGCGTACGTGTGCAGCCGGCCGCTGCGCTGCCCT
ACCCGACACGAGGCCCGCGT

Downstream 100 bases:

>100_bases
CGCCTTCCGTTCCCGGCCGCCCGCCGCCGCTGCGCACCGACGCGCCGCCGACCGATGCCGACGCGTGCGACGGATTGCGC
GTGCAGGACCTCGATCTGAA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MDIALSGHAPNRLGALHAPDEVERAVAHRLGPHRMAAHGRDPFHAELYEVPLHHGALLELCYGRETRIDFGDDADHFLFR
LTLSGSCELQAGQAIVHAGPGELTVSSPARASRLRTSRDCRNLVLRLERRALERKLQDMLGTTLARPLQFEVDASRHRAG
AALVLPTFDYLCRLGTQPALGAAAATFGADLSAWLMSLLLTHLPHSYSDALARGTPPLPAPVRRACAYVDAHLGEPLALA
ALARVAGVAPRTLQHAFRTFLNTTPAAYVRDRRLAAVHAALQRGDARSVTDVLLAHGIHGFGHFAKAYARRYGHPPSVTA
RQPR

Sequences:

>Translated_324_residues
MDIALSGHAPNRLGALHAPDEVERAVAHRLGPHRMAAHGRDPFHAELYEVPLHHGALLELCYGRETRIDFGDDADHFLFR
LTLSGSCELQAGQAIVHAGPGELTVSSPARASRLRTSRDCRNLVLRLERRALERKLQDMLGTTLARPLQFEVDASRHRAG
AALVLPTFDYLCRLGTQPALGAAAATFGADLSAWLMSLLLTHLPHSYSDALARGTPPLPAPVRRACAYVDAHLGEPLALA
ALARVAGVAPRTLQHAFRTFLNTTPAAYVRDRRLAAVHAALQRGDARSVTDVLLAHGIHGFGHFAKAYARRYGHPPSVTA
RQPR
>Mature_324_residues
MDIALSGHAPNRLGALHAPDEVERAVAHRLGPHRMAAHGRDPFHAELYEVPLHHGALLELCYGRETRIDFGDDADHFLFR
LTLSGSCELQAGQAIVHAGPGELTVSSPARASRLRTSRDCRNLVLRLERRALERKLQDMLGTTLARPLQFEVDASRHRAG
AALVLPTFDYLCRLGTQPALGAAAATFGADLSAWLMSLLLTHLPHSYSDALARGTPPLPAPVRRACAYVDAHLGEPLALA
ALARVAGVAPRTLQHAFRTFLNTTPAAYVRDRRLAAVHAALQRGDARSVTDVLLAHGIHGFGHFAKAYARRYGHPPSVTA
RQPR

Specific function: Probably involved in the positive regulation of the thc operon for the degradation of the thiocarbamate herbicide EPTC [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35193; Mature: 35193

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIALSGHAPNRLGALHAPDEVERAVAHRLGPHRMAAHGRDPFHAELYEVPLHHGALLEL
CCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHCCCCCCHHHHH
CYGRETRIDFGDDADHFLFRLTLSGSCELQAGQAIVHAGPGELTVSSPARASRLRTSRDC
HCCCCCCCCCCCCCCEEEEEEEECCCCEEECCCEEEECCCCCEEECCCHHHHHHHHHHHH
RNLVLRLERRALERKLQDMLGTTLARPLQFEVDASRHRAGAALVLPTFDYLCRLGTQPAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHCCCCEEEHHHHHHHHHCCCCCCH
GAAAATFGADLSAWLMSLLLTHLPHSYSDALARGTPPLPAPVRRACAYVDAHLGEPLALA
HHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHH
ALARVAGVAPRTLQHAFRTFLNTTPAAYVRDRRLAAVHAALQRGDARSVTDVLLAHGIHG
HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHH
FGHFAKAYARRYGHPPSVTARQPR
HHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDIALSGHAPNRLGALHAPDEVERAVAHRLGPHRMAAHGRDPFHAELYEVPLHHGALLEL
CCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHCCCCCCHHHHH
CYGRETRIDFGDDADHFLFRLTLSGSCELQAGQAIVHAGPGELTVSSPARASRLRTSRDC
HCCCCCCCCCCCCCCEEEEEEEECCCCEEECCCEEEECCCCCEEECCCHHHHHHHHHHHH
RNLVLRLERRALERKLQDMLGTTLARPLQFEVDASRHRAGAALVLPTFDYLCRLGTQPAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHCCCCEEEHHHHHHHHHCCCCCCH
GAAAATFGADLSAWLMSLLLTHLPHSYSDALARGTPPLPAPVRRACAYVDAHLGEPLALA
HHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHH
ALARVAGVAPRTLQHAFRTFLNTTPAAYVRDRRLAAVHAALQRGDARSVTDVLLAHGIHG
HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHH
FGHFAKAYARRYGHPPSVTARQPR
HHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836301 [H]