BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is kduD [H]

Identifier: 189351999

GI number: 189351999

Start: 19246

End: 19968

Strand: Reverse

Name: kduD [H]

Synonym: BMULJ_03216

Alternate gene names: 189351999

Gene position: 19968-19246 (Counterclockwise)

Preceding gene: 189352000

Following gene: 189351997

Centisome position: 0.81

GC content: 67.63

Gene sequence:

>723_bases
ATGAGCCAAGCGCAGACGTTTGAGCGCAAGACCGTCGTCGTGACGGGCGGTACATCGGGAATCGGCGCACATACCGCACT
GCGTTTCGCAAAAGCGGGCGCGTCGGTCGTCAGCATCGGGCTGCAGGCCGCGGGCCCGCATGCGCCGGTGCACGAGCGCA
TCCGGCACGTCGAGCTCGACGTGGCCGACAGCGACGCGCTGACGCGCATGATCGGCGCCCTGCCGCGCATCGACGTGCTC
GTCAACGGCGTCGGCATCAGCCGGCACGCGGACGAATATCGGATGGACGAATTCGAGCACGTGCTGAACGTGAATCTCAC
GTCGGTGATGCGGGCGTCGGACGCCGCGCGCCCGGCGCTGTCCGTGGATGGCGGCGCGATCGTCAACATCGCGTCGATGT
ACACGTATTTCGGCAGCAAGGACCGACCCGCGTATAGCGCGAGCAAAGGCGGGATCGCGCAGCTCACACGTTCGCTCGCG
CAGGCCTGGGCCGACCGCGGCATTCGCGTCAATGCGGTCGCGCCGGGCTGGATCGATACGCCGCTCAGCAGCGCGTTGAT
GGCCGATGCGCAGGCGTCGCGTCGAATCCTCGAGCGCACGCCGCTCGGACGATGGGGCAAGCCCGACGAAGTCGCCGACG
TGATCCTGTTTCTCTGCTCGCCCGGCGCGTCGTTCGTGACCGGTGCGATCGTTCCCGTCGACGGCGGCTATTCGACGGTC
TGA

Upstream 100 bases:

>100_bases
GGCTTCGACGCGCTGCTCGCCGACCGCACGCAGATCAAGGTTCTCGTTTCACCGGCGCTCGGCGCGAGCCGCCGCACCTA
TGCCTCGGGGAGCATCGAAC

Downstream 100 bases:

>100_bases
TCGAATGTGCGGCGCTTCGTCGATGCGCGTATGTGGCGGCACGCAGCGCATTCGCTTCGCGCGCCGCCAGGCGCGTCACG
CCGCGCTTTCGCAGTCGCTC

Product: 2-deoxy-D-gluconate 3-dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSQAQTFERKTVVVTGGTSGIGAHTALRFAKAGASVVSIGLQAAGPHAPVHERIRHVELDVADSDALTRMIGALPRIDVL
VNGVGISRHADEYRMDEFEHVLNVNLTSVMRASDAARPALSVDGGAIVNIASMYTYFGSKDRPAYSASKGGIAQLTRSLA
QAWADRGIRVNAVAPGWIDTPLSSALMADAQASRRILERTPLGRWGKPDEVADVILFLCSPGASFVTGAIVPVDGGYSTV

Sequences:

>Translated_240_residues
MSQAQTFERKTVVVTGGTSGIGAHTALRFAKAGASVVSIGLQAAGPHAPVHERIRHVELDVADSDALTRMIGALPRIDVL
VNGVGISRHADEYRMDEFEHVLNVNLTSVMRASDAARPALSVDGGAIVNIASMYTYFGSKDRPAYSASKGGIAQLTRSLA
QAWADRGIRVNAVAPGWIDTPLSSALMADAQASRRILERTPLGRWGKPDEVADVILFLCSPGASFVTGAIVPVDGGYSTV
>Mature_239_residues
SQAQTFERKTVVVTGGTSGIGAHTALRFAKAGASVVSIGLQAAGPHAPVHERIRHVELDVADSDALTRMIGALPRIDVLV
NGVGISRHADEYRMDEFEHVLNVNLTSVMRASDAARPALSVDGGAIVNIASMYTYFGSKDRPAYSASKGGIAQLTRSLAQ
AWADRGIRVNAVAPGWIDTPLSSALMADAQASRRILERTPLGRWGKPDEVADVILFLCSPGASFVTGAIVPVDGGYSTV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=234, Percent_Identity=32.0512820512821, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=32.5670498084291, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI66933014, Length=242, Percent_Identity=30.5785123966942, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI4758504, Length=248, Percent_Identity=32.258064516129, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=29.0836653386454, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=30.46875, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI59889578, Length=223, Percent_Identity=32.7354260089686, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=29.7959183673469, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI10190704, Length=242, Percent_Identity=30.5785123966942, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=27.8048780487805, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI83715985, Length=248, Percent_Identity=29.8387096774194, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI126723750, Length=142, Percent_Identity=31.6901408450704, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4503301, Length=252, Percent_Identity=24.2063492063492, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=36.6935483870968, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=31.0204081632653, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=34.2857142857143, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=32.0158102766798, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=32.9218106995885, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=32.0833333333333, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=32.6530612244898, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=33.4710743801653, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=31.8367346938775, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=29.4354838709677, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=31.3253012048193, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1789057, Length=175, Percent_Identity=30.8571428571429, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=34.5833333333333, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=31.2977099236641, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=31.8181818181818, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=33.7209302325581, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=31.9672131147541, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994600, Length=244, Percent_Identity=34.8360655737705, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=30.9160305343511, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=30, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=28.9795918367347, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=32.1138211382114, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=29.1666666666667, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=30.4182509505703, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=28.4090909090909, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=28.8973384030418, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=30.3149606299213, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=29.1512915129151, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=29.3893129770992, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=27.1698113207547, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=28.6259541984733, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=29.0566037735849, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=29.6, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=30.46875, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=28.030303030303, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=29.0566037735849, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=27.0676691729323, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=30.3501945525292, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=30.1204819277108, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=199, Percent_Identity=27.1356783919598, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=175, Percent_Identity=27.4285714285714, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322861, Length=252, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=249, Percent_Identity=28.1124497991968, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=32.7800829875519, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=35.3909465020576, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=33.9920948616601, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=35.4581673306773, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24643142, Length=236, Percent_Identity=33.4745762711864, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=34.136546184739, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=35.6, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=31.5789473684211, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17737361, Length=247, Percent_Identity=30.3643724696356, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21358495, Length=241, Percent_Identity=30.2904564315353, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665243, Length=226, Percent_Identity=28.7610619469027, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221331218, Length=220, Percent_Identity=28.6363636363636, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25280; Mature: 25149

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAQTFERKTVVVTGGTSGIGAHTALRFAKAGASVVSIGLQAAGPHAPVHERIRHVELD
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHEEECHHCCCCCCCHHHHHHEEEEC
VADSDALTRMIGALPRIDVLVNGVGISRHADEYRMDEFEHVLNVNLTSVMRASDAARPAL
CCCHHHHHHHHHCCCCEEHEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCE
SVDGGAIVNIASMYTYFGSKDRPAYSASKGGIAQLTRSLAQAWADRGIRVNAVAPGWIDT
ECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCC
PLSSALMADAQASRRILERTPLGRWGKPDEVADVILFLCSPGASFVTGAIVPVDGGYSTV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHCCEEEECCCCCCCC
>Mature Secondary Structure 
SQAQTFERKTVVVTGGTSGIGAHTALRFAKAGASVVSIGLQAAGPHAPVHERIRHVELD
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHEEECHHCCCCCCCHHHHHHEEEEC
VADSDALTRMIGALPRIDVLVNGVGISRHADEYRMDEFEHVLNVNLTSVMRASDAARPAL
CCCHHHHHHHHHCCCCEEHEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCE
SVDGGAIVNIASMYTYFGSKDRPAYSASKGGIAQLTRSLAQAWADRGIRVNAVAPGWIDT
ECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCC
PLSSALMADAQASRRILERTPLGRWGKPDEVADVILFLCSPGASFVTGAIVPVDGGYSTV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]