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The map label for this gene is 189184738

Identifier: 189184738

GI number: 189184738

Start: 1862337

End: 1863476

Strand: Direct

Name: 189184738

Synonym: OTT_1831

Alternate gene names: NA

Gene position: 1862337-1863476 (Clockwise)

Preceding gene: 189184737

Following gene: 189184739

Centisome position: 92.7

GC content: 27.72

Gene sequence:

>1140_bases
ATGAAAAACGTGTGTAAAAAATTAGCCATTATTTTATCATTAATATTATTAAATACAGCAGCTGTTGCAGCAGAGCAAAG
CATACAACAAGATTTAATTCAAGATAGAGCTATACTAGCTAAGGAATATTTTAATATTGGAAGCTCTTTTTTAAAATTAA
AAAAATATCAAGAAGCTATAGAAAATTTTGATATTGCTATTAAGTATGATCCAAGTTATGCGTCATCATATAATAGCAAA
GGAATAGCTTTAGATGATTTGGGAAAGCCACTGGAAGCTGTAGAAAATTTTAATTTGGCTATTAAATACGATCCTAGTTT
TGTAGGAGCGTATAATAACAAAGCTATGTCTTATAGAAAACTTGGAAAAAATGAAGAAGCTATAACACTGTGTAATCTTG
CAATCAAATATAAACCTAATTTTTCAGAAGCTTATATTAATAAAGGAGCTTCGTTGAATGACTTAGGACGGTATGAAGAA
GCAATGGAAAACTTTGATGTTGCTATTAGGTATAACTCTAGTTATCCAGAAGCTTATTATAACAAAGGCATAGCGTTAAT
GAATTTAGGATCCATTCAAGAAGCTATTGAAAGCTGTGATATAGCTATTAAATACAGACCAAATTATTCAGAAGCATATC
ATAATAAAGGTTTAACTTTAGCAATTTTGGGACAATTTCAGAATGCAATAGAACATTTTGATTTAGCTATTAAATACGAT
CCTAATGATTTAAAAGCATATAATAATAAAGGATATGTATTAAATCTATTAAAGAGATATGCAGAAGCAATGGAAAGTTG
TAACCTAGCTATTGAAATTGATCCAAATTGTGCAGATGCTTATTGTCTTAAAGGAATGGTTTTTGAGAAATTAGGAAAAC
ATCAAGAAGCAATTAAAAATTATGATATAGCTATTAAATATAATCCTAATTTTGATAAAAATTATCTTGAAAAAGGAATT
TCATTAGTAAACTTAGGGCAGTACTCAAGCGCTAAAGAGAATTTTTTATTAGCTATTAAATATAATCCTAATATCATTTC
AGAACATGAAACAATGTTAAAAAGGTTAACAAAATTGAAGAATTTTACTGGAGTAAAAGAGTATGAGCAAAAACTACAGA
TATTGAAAAAATACTCTTGA

Upstream 100 bases:

>100_bases
AATACAGGATGAATTTAATAATACTTCTAATTCAGCAGTTATTTTAACTGTCAAACAAGCAGTAAAAAATTTAAAGGATA
ATAAATGATTAGTAATTAAT

Downstream 100 bases:

>100_bases
TGAATTTTCAGAATCAAGGCAATTTCACAAGGGGATCGCAGTTATTTGCCCATAAGTTAAGAATGTTTGGGCAAGGTAGT
ACCAACGTTTTTATAATTGG

Product: TPR repeat-containing protein 01_10

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKNVCKKLAIILSLILLNTAAVAAEQSIQQDLIQDRAILAKEYFNIGSSFLKLKKYQEAIENFDIAIKYDPSYASSYNSK
GIALDDLGKPLEAVENFNLAIKYDPSFVGAYNNKAMSYRKLGKNEEAITLCNLAIKYKPNFSEAYINKGASLNDLGRYEE
AMENFDVAIRYNSSYPEAYYNKGIALMNLGSIQEAIESCDIAIKYRPNYSEAYHNKGLTLAILGQFQNAIEHFDLAIKYD
PNDLKAYNNKGYVLNLLKRYAEAMESCNLAIEIDPNCADAYCLKGMVFEKLGKHQEAIKNYDIAIKYNPNFDKNYLEKGI
SLVNLGQYSSAKENFLLAIKYNPNIISEHETMLKRLTKLKNFTGVKEYEQKLQILKKYS

Sequences:

>Translated_379_residues
MKNVCKKLAIILSLILLNTAAVAAEQSIQQDLIQDRAILAKEYFNIGSSFLKLKKYQEAIENFDIAIKYDPSYASSYNSK
GIALDDLGKPLEAVENFNLAIKYDPSFVGAYNNKAMSYRKLGKNEEAITLCNLAIKYKPNFSEAYINKGASLNDLGRYEE
AMENFDVAIRYNSSYPEAYYNKGIALMNLGSIQEAIESCDIAIKYRPNYSEAYHNKGLTLAILGQFQNAIEHFDLAIKYD
PNDLKAYNNKGYVLNLLKRYAEAMESCNLAIEIDPNCADAYCLKGMVFEKLGKHQEAIKNYDIAIKYNPNFDKNYLEKGI
SLVNLGQYSSAKENFLLAIKYNPNIISEHETMLKRLTKLKNFTGVKEYEQKLQILKKYS
>Mature_379_residues
MKNVCKKLAIILSLILLNTAAVAAEQSIQQDLIQDRAILAKEYFNIGSSFLKLKKYQEAIENFDIAIKYDPSYASSYNSK
GIALDDLGKPLEAVENFNLAIKYDPSFVGAYNNKAMSYRKLGKNEEAITLCNLAIKYKPNFSEAYINKGASLNDLGRYEE
AMENFDVAIRYNSSYPEAYYNKGIALMNLGSIQEAIESCDIAIKYRPNYSEAYHNKGLTLAILGQFQNAIEHFDLAIKYD
PNDLKAYNNKGYVLNLLKRYAEAMESCNLAIEIDPNCADAYCLKGMVFEKLGKHQEAIKNYDIAIKYNPNFDKNYLEKGI
SLVNLGQYSSAKENFLLAIKYNPNIISEHETMLKRLTKLKNFTGVKEYEQKLQILKKYS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=288, Percent_Identity=29.8611111111111, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI32307150, Length=288, Percent_Identity=29.8611111111111, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI118766330, Length=296, Percent_Identity=24.6621621621622, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI118766328, Length=296, Percent_Identity=24.6621621621622, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI310123097, Length=266, Percent_Identity=28.1954887218045, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310110582, Length=266, Percent_Identity=28.1954887218045, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI310131789, Length=266, Percent_Identity=28.1954887218045, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI170784867, Length=268, Percent_Identity=26.865671641791, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI83415184, Length=389, Percent_Identity=22.879177377892, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI301336134, Length=389, Percent_Identity=22.879177377892, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI221219056, Length=288, Percent_Identity=22.9166666666667, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI262206280, Length=288, Percent_Identity=22.9166666666667, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI22749211, Length=341, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=348, Percent_Identity=25.8620689655172, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115532690, Length=348, Percent_Identity=25.8620689655172, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25147174, Length=237, Percent_Identity=25.7383966244726, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647755, Length=277, Percent_Identity=28.158844765343, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24585827, Length=277, Percent_Identity=28.158844765343, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24585829, Length=277, Percent_Identity=28.158844765343, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24647123, Length=244, Percent_Identity=27.4590163934426, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI161076610, Length=244, Percent_Identity=28.6885245901639, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920486, Length=244, Percent_Identity=28.6885245901639, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17137540, Length=283, Percent_Identity=21.9081272084806, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 43052; Mature: 43052

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVCKKLAIILSLILLNTAAVAAEQSIQQDLIQDRAILAKEYFNIGSSFLKLKKYQEAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ENFDIAIKYDPSYASSYNSKGIALDDLGKPLEAVENFNLAIKYDPSFVGAYNNKAMSYRK
HCCCEEEEECCCHHCCCCCCCCCHHHCCCHHHHHCCCCEEEEECCCEEECCCCCHHHHHH
LGKNEEAITLCNLAIKYKPNFSEAYINKGASLNDLGRYEEAMENFDVAIRYNSSYPEAYY
CCCCCCEEEEEEEEEEECCCCHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHH
NKGIALMNLGSIQEAIESCDIAIKYRPNYSEAYHNKGLTLAILGQFQNAIEHFDLAIKYD
HCCEEEEECHHHHHHHHHCCEEEEECCCHHHHHHCCCCEEEEHHHHHHHHHHCEEEEEEC
PNDLKAYNNKGYVLNLLKRYAEAMESCNLAIEIDPNCADAYCLKGMVFEKLGKHQEAIKN
CCHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHC
YDIAIKYNPNFDKNYLEKGISLVNLGQYSSAKENFLLAIKYNPNIISEHETMLKRLTKLK
CCEEEEECCCCCHHHHHCCCCEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
NFTGVKEYEQKLQILKKYS
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNVCKKLAIILSLILLNTAAVAAEQSIQQDLIQDRAILAKEYFNIGSSFLKLKKYQEAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ENFDIAIKYDPSYASSYNSKGIALDDLGKPLEAVENFNLAIKYDPSFVGAYNNKAMSYRK
HCCCEEEEECCCHHCCCCCCCCCHHHCCCHHHHHCCCCEEEEECCCEEECCCCCHHHHHH
LGKNEEAITLCNLAIKYKPNFSEAYINKGASLNDLGRYEEAMENFDVAIRYNSSYPEAYY
CCCCCCEEEEEEEEEEECCCCHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHH
NKGIALMNLGSIQEAIESCDIAIKYRPNYSEAYHNKGLTLAILGQFQNAIEHFDLAIKYD
HCCEEEEECHHHHHHHHHCCEEEEECCCHHHHHHCCCCEEEEHHHHHHHHHHCEEEEEEC
PNDLKAYNNKGYVLNLLKRYAEAMESCNLAIEIDPNCADAYCLKGMVFEKLGKHQEAIKN
CCHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHC
YDIAIKYNPNFDKNYLEKGISLVNLGQYSSAKENFLLAIKYNPNIISEHETMLKRLTKLK
CCEEEEECCCCCHHHHHCCCCEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
NFTGVKEYEQKLQILKKYS
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]