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The map label for this gene is frr [H]

Identifier: 189184500

GI number: 189184500

Start: 1626377

End: 1626940

Strand: Direct

Name: frr [H]

Synonym: OTT_1593

Alternate gene names: 189184500

Gene position: 1626377-1626940 (Clockwise)

Preceding gene: 189184484

Following gene: 189184502

Centisome position: 80.96

GC content: 29.26

Gene sequence:

>564_bases
ATGAATCATGAAGAACTAATTAATTCATTAACAAAAAAAATGAACGGCGCACTACAAGTACTTGATGCAGATCTTAAAGG
CTTAAGAGTTGGACAAGCATCTGCATATTTTTTAGATCCAGTACAAGTTGAAGCATATAATAGCAAAGTTCCAATATTAC
AAGTTGCAACAATTTCAGTATCAGATACAAAAACTATCCTTGTTCAAGTATGGGACAAAAGTCTTGTTAAAGCTGTTAAA
AAAGCAATTATGGAAGCAAATTTAGGAGTTTCTATTATTTCAGATGACAATCAAATAATAAGATTACAGCTTCCTATTCC
AAGTGAGGAACGTAGAAAAGAATTAGTTAAAATAGCGCATAAATATCAAGAAAAAAGCAAAATCATTGTTCGAAATATTA
GACGTGATGGCATAGAGCTCATTAAGCAAATGGAACAAAACACTGAGTGCTCAAAAGATGAAGCACACATATACAGCAAA
GAAATACAGGAATTAACAGATAAATATTGTGATAAAATTGATAAAATAATTAAACTTAAAGAACAAGATATTATTAATTT
ATAA

Upstream 100 bases:

>100_bases
TTATTAGCAAGATAATAAACTTTTAAATTAATTATCCTGCTTGCATAATATAGAGTTATATGATTATTTTTATAGATATT
TAATAATAAATATTAGCGTT

Downstream 100 bases:

>100_bases
ATATTTCAAAATTATTGTATTAATTGTATTAAAAAAAAAACTAAAAAGCTCTCACTTGCTAGCTTACATCACTTAGTATA
ACGCTAATACTTTTCTATCA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNHEELINSLTKKMNGALQVLDADLKGLRVGQASAYFLDPVQVEAYNSKVPILQVATISVSDTKTILVQVWDKSLVKAVK
KAIMEANLGVSIISDDNQIIRLQLPIPSEERRKELVKIAHKYQEKSKIIVRNIRRDGIELIKQMEQNTECSKDEAHIYSK
EIQELTDKYCDKIDKIIKLKEQDIINL

Sequences:

>Translated_187_residues
MNHEELINSLTKKMNGALQVLDADLKGLRVGQASAYFLDPVQVEAYNSKVPILQVATISVSDTKTILVQVWDKSLVKAVK
KAIMEANLGVSIISDDNQIIRLQLPIPSEERRKELVKIAHKYQEKSKIIVRNIRRDGIELIKQMEQNTECSKDEAHIYSK
EIQELTDKYCDKIDKIIKLKEQDIINL
>Mature_187_residues
MNHEELINSLTKKMNGALQVLDADLKGLRVGQASAYFLDPVQVEAYNSKVPILQVATISVSDTKTILVQVWDKSLVKAVK
KAIMEANLGVSIISDDNQIIRLQLPIPSEERRKELVKIAHKYQEKSKIIVRNIRRDGIELIKQMEQNTECSKDEAHIYSK
EIQELTDKYCDKIDKIIKLKEQDIINL

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Escherichia coli, GI1786368, Length=175, Percent_Identity=33.7142857142857, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 21355; Mature: 21355

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHEELINSLTKKMNGALQVLDADLKGLRVGQASAYFLDPVQVEAYNSKVPILQVATISV
CCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCEEEECCEEEEECCCCCCEEEEEEEEE
SDTKTILVQVWDKSLVKAVKKAIMEANLGVSIISDDNQIIRLQLPIPSEERRKELVKIAH
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHH
KYQEKSKIIVRNIRRDGIELIKQMEQNTECSKDEAHIYSKEIQELTDKYCDKIDKIIKLK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQDIINL
HHHHCCC
>Mature Secondary Structure
MNHEELINSLTKKMNGALQVLDADLKGLRVGQASAYFLDPVQVEAYNSKVPILQVATISV
CCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCEEEECCEEEEECCCCCCEEEEEEEEE
SDTKTILVQVWDKSLVKAVKKAIMEANLGVSIISDDNQIIRLQLPIPSEERRKELVKIAH
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHH
KYQEKSKIIVRNIRRDGIELIKQMEQNTECSKDEAHIYSKEIQELTDKYCDKIDKIIKLK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQDIINL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA