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The map label for this gene is ubiA [H]

Identifier: 189184302

GI number: 189184302

Start: 1427733

End: 1428608

Strand: Direct

Name: ubiA [H]

Synonym: OTT_1395

Alternate gene names: 189184302

Gene position: 1427733-1428608 (Clockwise)

Preceding gene: 189184299

Following gene: 189184304

Centisome position: 71.07

GC content: 28.88

Gene sequence:

>876_bases
ATGACTACTTTTTTAAGGATAATATACCAATTTAATCTTTTAATAAAGCTATCTCGTTTAAACAATCCAGTTGGTATTTT
TTTGTTATTTTTTCCATGTTGTTTTGGAATAGGATTAGTTTCATTAGAACAAGTCAAATATAACAGTTTAGTTATTTTTT
TCATTGGTAGTATATTAATGCGCAGTTTTGGCTGCATAGTAAATGATATTGTAGATAAAGATATTGACTCTCGAGTTGCT
AGAACTAAACTTCGTCCACTTGCAAACAATCAAATAACAGTTACTAGTGCAGTTATATATCTAATAGTTATATCACTGGC
TGCGTTAATGCTGCTAATACAACTATCAGATTTAGCAATTATTTTGGCTATTTTAGCATCAACATTAATCTTTATTTACC
CATTTATGAAGCGCCTTACTTATTATCCTCAGGTTATTTTAGGCATTACTTTTAATTCTGGAGCTTTGATATCTTATGCT
AACATCACCAATAATTTAACTATAGCAAGTGTTGTAATGTATATTGGCTGTATTTTTTGGACTATTGGTTATGATACAAT
TTATGCCTTTGCAGATGCTGGTGATGATGAAAAGATAAAAGTTAAATCTTTAGCATTAGTGCTTAAAAATAACAAGTATA
AGCTATGGATTTTAGCATCACTATATCTTATATTTATCAGTATGTTCGTTGAATCAATATTATTATCTGCTTTTAAATTA
TCAATTTTTGCTGTGCTATTTATAGTTGCTGCTACATGCTTATTAATGTGGCAAATTGCTACATTAGATGTTACTCAACC
ACTGAATTGTTTAACACGGTTTAAAGCAAATACTATTGTCGGATTGCTGCTTTTTATAGCTATGATTTTGCTATAA

Upstream 100 bases:

>100_bases
TTTCTGCCAATCATTTTGCCACTTTGGTTCATTTTCTAGATAGTTGTAATTTGCTGACAATTTTGCCATAATTTTCCTTT
ACATTTGATAGATATGATAA

Downstream 100 bases:

>100_bases
TAACATGAGTTTGATATAAGAAATAAGACTGTATGTGGTAACTCTTTACATTTTTTATTAAAAAGCTACTTTAAAATATC
CTTTTTAAAAGCCTACAAAA

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTTFLRIIYQFNLLIKLSRLNNPVGIFLLFFPCCFGIGLVSLEQVKYNSLVIFFIGSILMRSFGCIVNDIVDKDIDSRVA
RTKLRPLANNQITVTSAVIYLIVISLAALMLLIQLSDLAIILAILASTLIFIYPFMKRLTYYPQVILGITFNSGALISYA
NITNNLTIASVVMYIGCIFWTIGYDTIYAFADAGDDEKIKVKSLALVLKNNKYKLWILASLYLIFISMFVESILLSAFKL
SIFAVLFIVAATCLLMWQIATLDVTQPLNCLTRFKANTIVGLLLFIAMILL

Sequences:

>Translated_291_residues
MTTFLRIIYQFNLLIKLSRLNNPVGIFLLFFPCCFGIGLVSLEQVKYNSLVIFFIGSILMRSFGCIVNDIVDKDIDSRVA
RTKLRPLANNQITVTSAVIYLIVISLAALMLLIQLSDLAIILAILASTLIFIYPFMKRLTYYPQVILGITFNSGALISYA
NITNNLTIASVVMYIGCIFWTIGYDTIYAFADAGDDEKIKVKSLALVLKNNKYKLWILASLYLIFISMFVESILLSAFKL
SIFAVLFIVAATCLLMWQIATLDVTQPLNCLTRFKANTIVGLLLFIAMILL
>Mature_290_residues
TTFLRIIYQFNLLIKLSRLNNPVGIFLLFFPCCFGIGLVSLEQVKYNSLVIFFIGSILMRSFGCIVNDIVDKDIDSRVAR
TKLRPLANNQITVTSAVIYLIVISLAALMLLIQLSDLAIILAILASTLIFIYPFMKRLTYYPQVILGITFNSGALISYAN
ITNNLTIASVVMYIGCIFWTIGYDTIYAFADAGDDEKIKVKSLALVLKNNKYKLWILASLYLIFISMFVESILLSAFKLS
IFAVLFIVAATCLLMWQIATLDVTQPLNCLTRFKANTIVGLLLFIAMILL

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=286, Percent_Identity=34.965034965035, Blast_Score=165, Evalue=5e-41,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=29.8181818181818, Blast_Score=134, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17553718, Length=278, Percent_Identity=34.8920863309352, Blast_Score=168, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI32565247, Length=279, Percent_Identity=33.6917562724014, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17553720, Length=332, Percent_Identity=28.9156626506024, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32565245, Length=136, Percent_Identity=37.5, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=135, Percent_Identity=37.037037037037, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324370, Length=274, Percent_Identity=30.6569343065693, Blast_Score=133, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21355567, Length=279, Percent_Identity=36.5591397849462, Blast_Score=184, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32629; Mature: 32498

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFLRIIYQFNLLIKLSRLNNPVGIFLLFFPCCFGIGLVSLEQVKYNSLVIFFIGSILM
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSFGCIVNDIVDKDIDSRVARTKLRPLANNQITVTSAVIYLIVISLAALMLLIQLSDLAI
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAILASTLIFIYPFMKRLTYYPQVILGITFNSGALISYANITNNLTIASVVMYIGCIFW
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHH
TIGYDTIYAFADAGDDEKIKVKSLALVLKNNKYKLWILASLYLIFISMFVESILLSAFKL
HHHHHHHHHHHCCCCCCCCHHHHHHHEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
SIFAVLFIVAATCLLMWQIATLDVTQPLNCLTRFKANTIVGLLLFIAMILL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TTFLRIIYQFNLLIKLSRLNNPVGIFLLFFPCCFGIGLVSLEQVKYNSLVIFFIGSILM
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSFGCIVNDIVDKDIDSRVARTKLRPLANNQITVTSAVIYLIVISLAALMLLIQLSDLAI
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAILASTLIFIYPFMKRLTYYPQVILGITFNSGALISYANITNNLTIASVVMYIGCIFW
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHH
TIGYDTIYAFADAGDDEKIKVKSLALVLKNNKYKLWILASLYLIFISMFVESILLSAFKL
HHHHHHHHHHHCCCCCCCCHHHHHHHEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
SIFAVLFIVAATCLLMWQIATLDVTQPLNCLTRFKANTIVGLLLFIAMILL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA