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The map label for this gene is murA [H]

Identifier: 189183813

GI number: 189183813

Start: 946736

End: 948001

Strand: Reverse

Name: murA [H]

Synonym: OTT_0906

Alternate gene names: 189183813

Gene position: 948001-946736 (Counterclockwise)

Preceding gene: 189183815

Following gene: 189183812

Centisome position: 47.19

GC content: 34.52

Gene sequence:

>1266_bases
GTGAGTAGTATATTAGTTGAAGGTGGCAAATCATTAAGGGGCGAGATAAATATTAGTGGTGCTAAAAATGCAGCTTTACC
AATTATAGTTGCAAGCTTATTAAGTTCTAAAACTTTAGTTATCAATAATGTACCACAATTGTCAGATGTTAGTGATATGC
TATTCATATTGAAAAGTTGTGGTGTTCATGTAGAAATTGTTGAAAGCGGAACTATTGCATTAACAGCTAATAACATTAGC
TGTCACTTTTCTCCTCCATGTAATATAGTTAAAAAAATGAGGGCTTCTATTTGGATATTAGCTCCTTTATTATTACGTCT
TGGGCAAGTTAGAATAGCATTGCCAGGTGGATGTGCAATTGGGCAGAGACGTATTGACCTACATTTAGCTGCATTAAAGG
CATTTGGTGCTAATATTCAATTAGAGGAAGACTATATTAGCGCGAATTGTAGTAGTAGAATGCACGGTATAAGTTTCAAG
TTTGATAAGGTTTCAGTAGGAGCAACTATTACTGCTATTATGTGTGCAGTGCTAGCTAATGGTAGTACTAAACTTGCTAA
TTGTGCTCAAGAACCTGAAATTGCTGATTTATGTTATTGTTTAAGAAAAATGGGAGCAAACATTACAGGCATTGGTACTG
CTAATATTAGTATCATAGGAGTTAAAGAGCTTAATGGGGCTAATTACAGTATTATTCCTGACCGTATTGAAGCTGGCACT
TATATGGTAGCAGCAGCTATAACGCAAGGGAAAATTAAGCTTAATAATGTTATATTTAAACATCTTAAATCAGCAATTAC
AAAACTGCGGTTATCAGGCGCAATAATACAATATCAGAATGAAAATAGTTTAATTATCGAAGGAGCTAATATTATTAAGC
CTCTTAATATACAAACTAATCCATATCCAAATTTTCCAACTGACCTTCAAGCTCAATTTATGAGCCTAATGTCTATTGCA
GATGGAGTATCAATTATTACCGAGAATATATATGAAAATCGCTACATGCATGTATTTGAGCTAATTAAAATGGGAGCAAA
TATTGTCATTCAATCCAGAGAAGCAATAGTTACAGGAGTCAAGAAATTACATGGTGCTGATGTAATAGCAACAGACCTTA
GAGCTTCAGTATCTTTGGTTTTAGCTGGATTATCAGCTGCAGGGATTACTAGAGTTAAACGCATGCATCACTTAGACCGC
GGATATGAGTCTTTAGTTGAGAAATTACAGAACTGTAATGCAAGAGTCCAAAGAATTCCTGATTAG

Upstream 100 bases:

>100_bases
TTTATATAAGTTTATATACAAAGTAAAGTTTGGTCTAATAACGTTTAGAATTATAAGCATTAATAGTTCATAAAGTTAAA
ATTGTAAATGTTAATAATCG

Downstream 100 bases:

>100_bases
TATTTAGAAATTTGTATTTTATAATTGAGCTTGATATGCTATTATAAATAGGCTATATGTTAAGTTTAAGAGCAGTAATT
ACCATTATTATAGTATAAAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MSSILVEGGKSLRGEINISGAKNAALPIIVASLLSSKTLVINNVPQLSDVSDMLFILKSCGVHVEIVESGTIALTANNIS
CHFSPPCNIVKKMRASIWILAPLLLRLGQVRIALPGGCAIGQRRIDLHLAALKAFGANIQLEEDYISANCSSRMHGISFK
FDKVSVGATITAIMCAVLANGSTKLANCAQEPEIADLCYCLRKMGANITGIGTANISIIGVKELNGANYSIIPDRIEAGT
YMVAAAITQGKIKLNNVIFKHLKSAITKLRLSGAIIQYQNENSLIIEGANIIKPLNIQTNPYPNFPTDLQAQFMSLMSIA
DGVSIITENIYENRYMHVFELIKMGANIVIQSREAIVTGVKKLHGADVIATDLRASVSLVLAGLSAAGITRVKRMHHLDR
GYESLVEKLQNCNARVQRIPD

Sequences:

>Translated_421_residues
MSSILVEGGKSLRGEINISGAKNAALPIIVASLLSSKTLVINNVPQLSDVSDMLFILKSCGVHVEIVESGTIALTANNIS
CHFSPPCNIVKKMRASIWILAPLLLRLGQVRIALPGGCAIGQRRIDLHLAALKAFGANIQLEEDYISANCSSRMHGISFK
FDKVSVGATITAIMCAVLANGSTKLANCAQEPEIADLCYCLRKMGANITGIGTANISIIGVKELNGANYSIIPDRIEAGT
YMVAAAITQGKIKLNNVIFKHLKSAITKLRLSGAIIQYQNENSLIIEGANIIKPLNIQTNPYPNFPTDLQAQFMSLMSIA
DGVSIITENIYENRYMHVFELIKMGANIVIQSREAIVTGVKKLHGADVIATDLRASVSLVLAGLSAAGITRVKRMHHLDR
GYESLVEKLQNCNARVQRIPD
>Mature_420_residues
SSILVEGGKSLRGEINISGAKNAALPIIVASLLSSKTLVINNVPQLSDVSDMLFILKSCGVHVEIVESGTIALTANNISC
HFSPPCNIVKKMRASIWILAPLLLRLGQVRIALPGGCAIGQRRIDLHLAALKAFGANIQLEEDYISANCSSRMHGISFKF
DKVSVGATITAIMCAVLANGSTKLANCAQEPEIADLCYCLRKMGANITGIGTANISIIGVKELNGANYSIIPDRIEAGTY
MVAAAITQGKIKLNNVIFKHLKSAITKLRLSGAIIQYQNENSLIIEGANIIKPLNIQTNPYPNFPTDLQAQFMSLMSIAD
GVSIITENIYENRYMHVFELIKMGANIVIQSREAIVTGVKKLHGADVIATDLRASVSLVLAGLSAAGITRVKRMHHLDRG
YESLVEKLQNCNARVQRIPD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=47.6190476190476, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45343; Mature: 45212

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSILVEGGKSLRGEINISGAKNAALPIIVASLLSSKTLVINNVPQLSDVSDMLFILKSC
CCCEEECCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHC
GVHVEIVESGTIALTANNISCHFSPPCNIVKKMRASIWILAPLLLRLGQVRIALPGGCAI
CCEEEEEECCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
GQRRIDLHLAALKAFGANIQLEEDYISANCSSRMHGISFKFDKVSVGATITAIMCAVLAN
CCHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHCC
GSTKLANCAQEPEIADLCYCLRKMGANITGIGTANISIIGVKELNGANYSIIPDRIEAGT
CCCHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCEECCCCCCCCC
YMVAAAITQGKIKLNNVIFKHLKSAITKLRLSGAIIQYQNENSLIIEGANIIKPLNIQTN
EEEEEEEECCCEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCCEEECCCCCC
PYPNFPTDLQAQFMSLMSIADGVSIITENIYENRYMHVFELIKMGANIVIQSREAIVTGV
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHCCCCEEEECHHHHHHHH
KKLHGADVIATDLRASVSLVLAGLSAAGITRVKRMHHLDRGYESLVEKLQNCNARVQRIP
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
D
C
>Mature Secondary Structure 
SSILVEGGKSLRGEINISGAKNAALPIIVASLLSSKTLVINNVPQLSDVSDMLFILKSC
CCEEECCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHC
GVHVEIVESGTIALTANNISCHFSPPCNIVKKMRASIWILAPLLLRLGQVRIALPGGCAI
CCEEEEEECCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
GQRRIDLHLAALKAFGANIQLEEDYISANCSSRMHGISFKFDKVSVGATITAIMCAVLAN
CCHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHCC
GSTKLANCAQEPEIADLCYCLRKMGANITGIGTANISIIGVKELNGANYSIIPDRIEAGT
CCCHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCEECCCCCCCCC
YMVAAAITQGKIKLNNVIFKHLKSAITKLRLSGAIIQYQNENSLIIEGANIIKPLNIQTN
EEEEEEEECCCEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCCEEECCCCCC
PYPNFPTDLQAQFMSLMSIADGVSIITENIYENRYMHVFELIKMGANIVIQSREAIVTGV
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHCCCCEEEECHHHHHHHH
KKLHGADVIATDLRASVSLVLAGLSAAGITRVKRMHHLDRGYESLVEKLQNCNARVQRIP
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA