Click here to switch to the map view.

The map label for this gene is ftsZ [H]

Identifier: 189183812

GI number: 189183812

Start: 945179

End: 946531

Strand: Reverse

Name: ftsZ [H]

Synonym: OTT_0905

Alternate gene names: 189183812

Gene position: 946531-945179 (Counterclockwise)

Preceding gene: 189183813

Following gene: 189183811

Centisome position: 47.11

GC content: 34.66

Gene sequence:

>1353_bases
ATGAGTGCAGATTTACAAACTCCAGAAAAATTAACGGGAGCTCCAGTGATTACTGTATTTGGAGTAGGAGGAGGAGGAAG
TAACGCTGTAGATAATATGATTACATCCAATTTGCAAGGAGTAACTTTTATTGTCGCAAATACTGATGCTCAGGCATTAA
ACATGTCTTTAGCAGAAAATAAGATTCAGCTTGGAAAAAGTACTATGGGAGCTGGAGCTGATCCTAATGTTGGGGCAGCA
GCAGCAGAAGAGTCAGCCGATGAAATTAAACGTCATATCGAAAATAGTAATATGATATTCATTGCCGCTGGAATGGGTGG
AGGAACTGGAACCGGCGCAGCTCCAGTAGTTGCAAGAATTGCTAAAGAGCTTGGAATTCTCACTGTTGCAGTTGTAACAA
AACCTTTTACTCTTGAAGGTGGGCAAAGAATGAGAATCGCTGAAGCTGGAATTGAAGAATTGCAAAAGAATGTTGATACT
GTAATAATAATTCCAAATCAATATTTATTTAGAGTTAGTAATCATATCACTACTTTTATTGAAGCATTTAAGATGGCTGA
TACTGTGTTAACCGATGCAGTAACTAATATGACTAGTTTAATTAATTTGCCTGGACTAATTAATTTAGATTTTGCTGATG
TTGTTACTATTATCAAAAAAGGAGGAAGGTCAATGATGGGAACAGGAGAAGCTAGCGGCGAAGATAGAGCTATTAAGGCT
GCAGAAATTGCTATATCTAATCCTTTGCTTGATAATTCCTCTATCAGAAAAGCTGAGGGAGTATTGATTCATATTATTGG
TGGAAATGATCTCACTTTAATGGAAGTTGATGAAGCAGTAAATCGTATTCGTAAAGAAATAGATGATGATGAGTCTAGAA
TTATATTCGGCGCAACTTTCAATCCGGATTTACAAGGCAAGATAAAGATATCAGTAATTGCATCATCTATTTGCAATCAA
TTATCAGAAGAAAAGAAATCAGCAGAAGATACTGACTTAGTAGATGATAGTACCATAGAATGTATTAAAACAGATGAAGC
TGATAAATTTAATGCAAGTGAATTAAATTGCAATATGGCACATGACTCATCCAATGCTAATGTTACTAAAAATAGCGGTG
TTATCAACAATAAATTGCAAAAAGATGATAGCTTATCATTATTACACTCCTCATCTATAAGACAATTAGAAGAACCTCAA
ACAAAACCTAAGATGTCAATTTTTGCTAGAATGTGGCGTAGCATAAAATCTGATTATCCAACTGCTAAAGCAAGCGAAGA
TAATGATTCTCAAGTAGCATCTGATGGAAATATTTATGAAATACCAACTTTTTTAAGAAAAAATAAGAAATGA

Upstream 100 bases:

>100_bases
AAATAGTACTTACATACTATGTAAAATAATATAAGCAACTGTATGTATTACATATAAACAATTTATGATTAGTTAAGATT
AATTAAGGGCAGATTTTTTT

Downstream 100 bases:

>100_bases
TGATCAATATTTAGATTGATCTGCTAATTATTTTTACATAGTTATTCAATATCTAACATAAAAATTTAAGGAACTATTTT
TTATGATTACTTTAACCAGT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSADLQTPEKLTGAPVITVFGVGGGGSNAVDNMITSNLQGVTFIVANTDAQALNMSLAENKIQLGKSTMGAGADPNVGAA
AAEESADEIKRHIENSNMIFIAAGMGGGTGTGAAPVVARIAKELGILTVAVVTKPFTLEGGQRMRIAEAGIEELQKNVDT
VIIIPNQYLFRVSNHITTFIEAFKMADTVLTDAVTNMTSLINLPGLINLDFADVVTIIKKGGRSMMGTGEASGEDRAIKA
AEIAISNPLLDNSSIRKAEGVLIHIIGGNDLTLMEVDEAVNRIRKEIDDDESRIIFGATFNPDLQGKIKISVIASSICNQ
LSEEKKSAEDTDLVDDSTIECIKTDEADKFNASELNCNMAHDSSNANVTKNSGVINNKLQKDDSLSLLHSSSIRQLEEPQ
TKPKMSIFARMWRSIKSDYPTAKASEDNDSQVASDGNIYEIPTFLRKNKK

Sequences:

>Translated_450_residues
MSADLQTPEKLTGAPVITVFGVGGGGSNAVDNMITSNLQGVTFIVANTDAQALNMSLAENKIQLGKSTMGAGADPNVGAA
AAEESADEIKRHIENSNMIFIAAGMGGGTGTGAAPVVARIAKELGILTVAVVTKPFTLEGGQRMRIAEAGIEELQKNVDT
VIIIPNQYLFRVSNHITTFIEAFKMADTVLTDAVTNMTSLINLPGLINLDFADVVTIIKKGGRSMMGTGEASGEDRAIKA
AEIAISNPLLDNSSIRKAEGVLIHIIGGNDLTLMEVDEAVNRIRKEIDDDESRIIFGATFNPDLQGKIKISVIASSICNQ
LSEEKKSAEDTDLVDDSTIECIKTDEADKFNASELNCNMAHDSSNANVTKNSGVINNKLQKDDSLSLLHSSSIRQLEEPQ
TKPKMSIFARMWRSIKSDYPTAKASEDNDSQVASDGNIYEIPTFLRKNKK
>Mature_449_residues
SADLQTPEKLTGAPVITVFGVGGGGSNAVDNMITSNLQGVTFIVANTDAQALNMSLAENKIQLGKSTMGAGADPNVGAAA
AEESADEIKRHIENSNMIFIAAGMGGGTGTGAAPVVARIAKELGILTVAVVTKPFTLEGGQRMRIAEAGIEELQKNVDTV
IIIPNQYLFRVSNHITTFIEAFKMADTVLTDAVTNMTSLINLPGLINLDFADVVTIIKKGGRSMMGTGEASGEDRAIKAA
EIAISNPLLDNSSIRKAEGVLIHIIGGNDLTLMEVDEAVNRIRKEIDDDESRIIFGATFNPDLQGKIKISVIASSICNQL
SEEKKSAEDTDLVDDSTIECIKTDEADKFNASELNCNMAHDSSNANVTKNSGVINNKLQKDDSLSLLHSSSIRQLEEPQT
KPKMSIFARMWRSIKSDYPTAKASEDNDSQVASDGNIYEIPTFLRKNKK

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=293, Percent_Identity=48.8054607508532, Blast_Score=241, Evalue=8e-65,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 48121; Mature: 47990

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADLQTPEKLTGAPVITVFGVGGGGSNAVDNMITSNLQGVTFIVANTDAQALNMSLAEN
CCCCCCCCHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
KIQLGKSTMGAGADPNVGAAAAEESADEIKRHIENSNMIFIAAGMGGGTGTGAAPVVARI
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
AKELGILTVAVVTKPFTLEGGQRMRIAEAGIEELQKNVDTVIIIPNQYLFRVSNHITTFI
HHHHCEEEEEEEECCEEECCCCEEEHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHH
EAFKMADTVLTDAVTNMTSLINLPGLINLDFADVVTIIKKGGRSMMGTGEASGEDRAIKA
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
AEIAISNPLLDNSSIRKAEGVLIHIIGGNDLTLMEVDEAVNRIRKEIDDDESRIIFGATF
EEEEECCCCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCEEEEEEEC
NPDLQGKIKISVIASSICNQLSEEKKSAEDTDLVDDSTIECIKTDEADKFNASELNCNMA
CCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEC
HDSSNANVTKNSGVINNKLQKDDSLSLLHSSSIRQLEEPQTKPKMSIFARMWRSIKSDYP
CCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
TAKASEDNDSQVASDGNIYEIPTFLRKNKK
CCCCCCCCCCCCCCCCCEEECCHHHHCCCC
>Mature Secondary Structure 
SADLQTPEKLTGAPVITVFGVGGGGSNAVDNMITSNLQGVTFIVANTDAQALNMSLAEN
CCCCCCCHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
KIQLGKSTMGAGADPNVGAAAAEESADEIKRHIENSNMIFIAAGMGGGTGTGAAPVVARI
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
AKELGILTVAVVTKPFTLEGGQRMRIAEAGIEELQKNVDTVIIIPNQYLFRVSNHITTFI
HHHHCEEEEEEEECCEEECCCCEEEHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHH
EAFKMADTVLTDAVTNMTSLINLPGLINLDFADVVTIIKKGGRSMMGTGEASGEDRAIKA
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
AEIAISNPLLDNSSIRKAEGVLIHIIGGNDLTLMEVDEAVNRIRKEIDDDESRIIFGATF
EEEEECCCCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCEEEEEEEC
NPDLQGKIKISVIASSICNQLSEEKKSAEDTDLVDDSTIECIKTDEADKFNASELNCNMA
CCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEC
HDSSNANVTKNSGVINNKLQKDDSLSLLHSSSIRQLEEPQTKPKMSIFARMWRSIKSDYP
CCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
TAKASEDNDSQVASDGNIYEIPTFLRKNKK
CCCCCCCCCCCCCCCCCEEECCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]