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The map label for this gene is atrC1 [H]

Identifier: 189183734

GI number: 189183734

Start: 868246

End: 869664

Strand: Direct

Name: atrC1 [H]

Synonym: OTT_0827

Alternate gene names: 189183734

Gene position: 868246-869664 (Clockwise)

Preceding gene: 189183732

Following gene: 189183736

Centisome position: 43.22

GC content: 33.12

Gene sequence:

>1419_bases
ATGAGTATATTCAGAAAAAAAAGTTTTGACTTAGCTAAGTCTACGACAAATGTCAACAACTTAAAAAAAAGCTTTACTGC
TTTTGATTTAATATTATTAGGGCTTGGAGCTATTATTGGTACTGGAGTATTTTCGTTAACTGGTATGGTAGCTGCTAAAT
ATTCTGGACCTGCAGTAACAATATCTTATATTATAGCTGGAGTTGTTTGTATATTAGTAGCTTTAGCATATACTGAACTT
GCAGTTATGATTCCTGCATCTGGTAGCGTTTATACTTATTCTTATATAGCGCTTGGGGAAGTGTTTGCTTGGATAATGGC
TAGTGTTATAATTTTAGAATTAACATTTGGAGCTGCTACTGTAGCAGCTAGTTGGTCAGCTTATACTCAGGGGATATTAG
AGGCAGGTGGAATAATTATACCAAAAATATATGCAGCCACTCCATTTGAAGGTGGTATTATAAATCTACCTGCAGTATTA
ATTGTTGCATTTGCTAGCTTTGTTTTATATTTAGGAACACGCGATAGCAAAAGGTTAAATATAATTTTAGTTATTGTTAA
GCTTTTATCAGTTGGAATTTTTATAATTGTTGCAGCTCCACATTTTCAAGCAGAAAATTGGAAAAATTTTATGCCTTTTA
CAGTTAACAGCACTTTGGTTGGAGCATCCATTTTATTTTTTGCATTTACTGGATTTAGTGTACTAGCAGCAGCTGCTGAA
GAATGTAAAAATCCTACAAAGGATTTGACAGTGGGTATCATAGGATCTCTAATAATCTCAACAATAGTTTATGTTATTAT
TGCTGGATTATTAACTGGTATGGCTCCATTTGATCAGCTTGATAATGCTCAACCTTTAGCTTATGCTTTAAAGCTTAATG
GTAGTACTGTTGGCTCAGCGATTGTTGCAGTTGGAGCAATTAGTGGCATGACTACAGTTTTAATGCTAAATATTTATGGC
CAATCAAGAATATTCTTTGCTATTGCTAGAGATGGATTATTGCCAAAAATATTTCAAAAAGTACATCCTACATATGATAG
CCCATATGTTGCTATTTTATTTTTTGCGCTAATAGTAGCATTAATTGGAGGGTTTTTCCCTTATCAAACAGTAGCTCAGC
TATCAAGTATGGGAGCGCTTATTGATTATATGGTAGTATCTGTAATAGTAATGCTGCTTAGGATCCAAATGCCTGATGCT
GTTAGAGCATTTAAGTGTCCTGCTGTATTTGTTGTTGCTCCGATATCATTAGTATCTTGTATTTATTTGTTGTTTAAGCA
AATTCTTGATGAAGATGGTAATTTACTTGATACTGGAAAAATAATTATTGCTTGGATGGTATTGGTATTGGTATTATATT
TTATCTTCTATTATGCAAAACAATCTTGTCAAGCATTAGCTTATAAGAGCAAGCAATGA

Upstream 100 bases:

>100_bases
AATATTTAATCTTAAAATACTTCATAAATTTTTCTTTTTAGAATTTTTAGAAATGCTGATATAAATGTAGAGCAGTTAAT
TTTAGTATTTAGTATAATGT

Downstream 100 bases:

>100_bases
TATATTAATAGGGCGATTAGCTCAGTTGGTTAGAGCATTACGTTGACGTCGTAAGGGTCAGTGGTTCGAATCCTCTATCG
CCCACCAACCAAAGCTTTTA

Product: cationic amino acid transporter-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSIFRKKSFDLAKSTTNVNNLKKSFTAFDLILLGLGAIIGTGVFSLTGMVAAKYSGPAVTISYIIAGVVCILVALAYTEL
AVMIPASGSVYTYSYIALGEVFAWIMASVIILELTFGAATVAASWSAYTQGILEAGGIIIPKIYAATPFEGGIINLPAVL
IVAFASFVLYLGTRDSKRLNIILVIVKLLSVGIFIIVAAPHFQAENWKNFMPFTVNSTLVGASILFFAFTGFSVLAAAAE
ECKNPTKDLTVGIIGSLIISTIVYVIIAGLLTGMAPFDQLDNAQPLAYALKLNGSTVGSAIVAVGAISGMTTVLMLNIYG
QSRIFFAIARDGLLPKIFQKVHPTYDSPYVAILFFALIVALIGGFFPYQTVAQLSSMGALIDYMVVSVIVMLLRIQMPDA
VRAFKCPAVFVVAPISLVSCIYLLFKQILDEDGNLLDTGKIIIAWMVLVLVLYFIFYYAKQSCQALAYKSKQ

Sequences:

>Translated_472_residues
MSIFRKKSFDLAKSTTNVNNLKKSFTAFDLILLGLGAIIGTGVFSLTGMVAAKYSGPAVTISYIIAGVVCILVALAYTEL
AVMIPASGSVYTYSYIALGEVFAWIMASVIILELTFGAATVAASWSAYTQGILEAGGIIIPKIYAATPFEGGIINLPAVL
IVAFASFVLYLGTRDSKRLNIILVIVKLLSVGIFIIVAAPHFQAENWKNFMPFTVNSTLVGASILFFAFTGFSVLAAAAE
ECKNPTKDLTVGIIGSLIISTIVYVIIAGLLTGMAPFDQLDNAQPLAYALKLNGSTVGSAIVAVGAISGMTTVLMLNIYG
QSRIFFAIARDGLLPKIFQKVHPTYDSPYVAILFFALIVALIGGFFPYQTVAQLSSMGALIDYMVVSVIVMLLRIQMPDA
VRAFKCPAVFVVAPISLVSCIYLLFKQILDEDGNLLDTGKIIIAWMVLVLVLYFIFYYAKQSCQALAYKSKQ
>Mature_471_residues
SIFRKKSFDLAKSTTNVNNLKKSFTAFDLILLGLGAIIGTGVFSLTGMVAAKYSGPAVTISYIIAGVVCILVALAYTELA
VMIPASGSVYTYSYIALGEVFAWIMASVIILELTFGAATVAASWSAYTQGILEAGGIIIPKIYAATPFEGGIINLPAVLI
VAFASFVLYLGTRDSKRLNIILVIVKLLSVGIFIIVAAPHFQAENWKNFMPFTVNSTLVGASILFFAFTGFSVLAAAAEE
CKNPTKDLTVGIIGSLIISTIVYVIIAGLLTGMAPFDQLDNAQPLAYALKLNGSTVGSAIVAVGAISGMTTVLMLNIYGQ
SRIFFAIARDGLLPKIFQKVHPTYDSPYVAILFFALIVALIGGFFPYQTVAQLSSMGALIDYMVVSVIVMLLRIQMPDAV
RAFKCPAVFVVAPISLVSCIYLLFKQILDEDGNLLDTGKIIIAWMVLVLVLYFIFYYAKQSCQALAYKSKQ

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=436, Percent_Identity=30.9633027522936, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI110347453, Length=392, Percent_Identity=32.3979591836735, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI258614005, Length=420, Percent_Identity=29.2857142857143, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI258614003, Length=420, Percent_Identity=29.2857142857143, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI258645169, Length=420, Percent_Identity=30.2380952380952, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI181337167, Length=404, Percent_Identity=31.9306930693069, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI114326544, Length=432, Percent_Identity=29.1666666666667, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI114326550, Length=432, Percent_Identity=29.1666666666667, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI33286428, Length=413, Percent_Identity=28.3292978208232, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI115648063, Length=437, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI115648022, Length=437, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI186910308, Length=425, Percent_Identity=25.6470588235294, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI186910306, Length=425, Percent_Identity=25.6470588235294, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI186910304, Length=425, Percent_Identity=25.6470588235294, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI7657683, Length=407, Percent_Identity=26.5356265356265, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI87082250, Length=347, Percent_Identity=27.3775216138329, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786694, Length=386, Percent_Identity=24.6113989637306, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87081869, Length=393, Percent_Identity=23.6641221374046, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082023, Length=410, Percent_Identity=23.9024390243902, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081708, Length=484, Percent_Identity=21.4876033057851, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786789, Length=345, Percent_Identity=24.0579710144928, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1788480, Length=359, Percent_Identity=24.5125348189415, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=412, Percent_Identity=33.252427184466, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17533459, Length=407, Percent_Identity=30.958230958231, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17531343, Length=458, Percent_Identity=30.3493449781659, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI32566699, Length=362, Percent_Identity=25.9668508287293, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17540018, Length=448, Percent_Identity=25.8928571428571, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17568033, Length=506, Percent_Identity=25.296442687747, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982612, Length=404, Percent_Identity=24.5049504950495, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982608, Length=404, Percent_Identity=24.5049504950495, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24667468, Length=401, Percent_Identity=31.9201995012469, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI221512776, Length=413, Percent_Identity=30.0242130750605, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24666159, Length=413, Percent_Identity=30.0242130750605, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24668806, Length=423, Percent_Identity=28.6052009456265, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21356285, Length=423, Percent_Identity=28.6052009456265, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24668802, Length=423, Percent_Identity=28.6052009456265, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281366235, Length=411, Percent_Identity=30.9002433090024, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI116007820, Length=411, Percent_Identity=30.9002433090024, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI116007818, Length=411, Percent_Identity=30.9002433090024, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI85725152, Length=411, Percent_Identity=30.9002433090024, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI161077963, Length=399, Percent_Identity=30.0751879699248, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI45550968, Length=436, Percent_Identity=25.4587155963303, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19921172, Length=436, Percent_Identity=25.4587155963303, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357367, Length=360, Percent_Identity=24.7222222222222, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24651635, Length=403, Percent_Identity=26.7990074441687, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651633, Length=403, Percent_Identity=26.7990074441687, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331183, Length=428, Percent_Identity=27.1028037383178, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17647653, Length=428, Percent_Identity=27.1028037383178, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24664379, Length=428, Percent_Identity=27.1028037383178, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50667; Mature: 50536

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFRKKSFDLAKSTTNVNNLKKSFTAFDLILLGLGAIIGTGVFSLTGMVAAKYSGPAVT
CCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHH
ISYIIAGVVCILVALAYTELAVMIPASGSVYTYSYIALGEVFAWIMASVIILELTFGAAT
HHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VAASWSAYTQGILEAGGIIIPKIYAATPFEGGIINLPAVLIVAFASFVLYLGTRDSKRLN
HHHHHHHHHHHHHHCCCEEECCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHH
IILVIVKLLSVGIFIIVAAPHFQAENWKNFMPFTVNSTLVGASILFFAFTGFSVLAAAAE
HHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
ECKNPTKDLTVGIIGSLIISTIVYVIIAGLLTGMAPFDQLDNAQPLAYALKLNGSTVGSA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEECCCHHHHH
IVAVGAISGMTTVLMLNIYGQSRIFFAIARDGLLPKIFQKVHPTYDSPYVAILFFALIVA
HHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
LIGGFFPYQTVAQLSSMGALIDYMVVSVIVMLLRIQMPDAVRAFKCPAVFVVAPISLVSC
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHH
IYLLFKQILDEDGNLLDTGKIIIAWMVLVLVLYFIFYYAKQSCQALAYKSKQ
HHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SIFRKKSFDLAKSTTNVNNLKKSFTAFDLILLGLGAIIGTGVFSLTGMVAAKYSGPAVT
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHH
ISYIIAGVVCILVALAYTELAVMIPASGSVYTYSYIALGEVFAWIMASVIILELTFGAAT
HHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VAASWSAYTQGILEAGGIIIPKIYAATPFEGGIINLPAVLIVAFASFVLYLGTRDSKRLN
HHHHHHHHHHHHHHCCCEEECCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHH
IILVIVKLLSVGIFIIVAAPHFQAENWKNFMPFTVNSTLVGASILFFAFTGFSVLAAAAE
HHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
ECKNPTKDLTVGIIGSLIISTIVYVIIAGLLTGMAPFDQLDNAQPLAYALKLNGSTVGSA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEECCCHHHHH
IVAVGAISGMTTVLMLNIYGQSRIFFAIARDGLLPKIFQKVHPTYDSPYVAILFFALIVA
HHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
LIGGFFPYQTVAQLSSMGALIDYMVVSVIVMLLRIQMPDAVRAFKCPAVFVVAPISLVSC
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHH
IYLLFKQILDEDGNLLDTGKIIIAWMVLVLVLYFIFYYAKQSCQALAYKSKQ
HHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]