| Definition | Orientia tsutsugamushi str. Ikeda, complete genome. |
|---|---|
| Accession | NC_010793 |
| Length | 2,008,987 |
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The map label for this gene is rho [H]
Identifier: 189183421
GI number: 189183421
Start: 538046
End: 539551
Strand: Reverse
Name: rho [H]
Synonym: OTT_0514
Alternate gene names: 189183421
Gene position: 539551-538046 (Counterclockwise)
Preceding gene: 189183427
Following gene: 189183420
Centisome position: 26.86
GC content: 32.93
Gene sequence:
>1506_bases ATGACTACAGAAAAAGAACATAGAATAAAAAACATATTAAAACCTGTATCTAATAATAATCCAGCCAACAGCGAAGCTGC AGATTCTTCAGTTGAAATAACTGCTCATTTGAATGAACCAAAGAAAAAATCTCATGAAGCCTTGCAATGTTACGCTGAAA GTAAAGAACATAGAATAAAAAAAACATCCAAACCTGTATCTAACAATAATCCAGTTAACAGCGAAGCTGCAGGTTCTTCA GTTGAAATAACTGTTCATTTAAACGAACTAAAGAAAAAATCTCCTGAAGCCTTGCAATGTTATGCTGAAAGTTTAGCAAT TGAAAATGCTAGTTCATTAACTAAGAATGAACTAATATCAGCTATTTTAAAAATGGTGGTAGAACGTAACGGTATAGTTA TTGAAGAGGGAGTAATTGAAATTTTAAACGGAGGATTTGGTTTTTTACGATCACCAGAAGTAAATTATTTATCAGGAGCA GGCGATATTTATGTATCTTTAAGTCAGATTAAACGTTGTGAATTACGCACTGGAGATACTGTTGAAGGACAAATTAGAGC TCCTAAGTCTGGAGAACGTTACTTTGCTTTATTAAAAGTACTAAAAGTTAATGGAGAAGATATTAAAAAATCTATTCAAC GGCTACATTTTGATGATTTAGTAGCTTTATACCCAGAGGAAAAAATTTCTTTTGAAGTTGATCTAGATTATAAAAACCTT AGTACTAGAGTTATGGAACTAGTTTCCCCTATGGGAAAAGGGCAACGAGCTCTTATAGTCGCTCCACCTCGTACTGGTAA AACAATTTTATTGCAAAATATTGCTCATTCTATTGCTACTAATCATCCTGAAATTTACCTAATAGTATTGCTAATAGGAG AAAGGCCAGAAGAAGTTACCGATATGATTAGGTCAGTTAAAGGAGAAGTTGTAAGTTCTACTTTTGATGAGCCAGCAGTA CGGCATACTCAACTAGCTGAAATTGTAATTGAAAAAGCAAAAAGATTGGTAGAGCATAAAAGAGATGTAGTAATATTACT GGATTCAATCACTAGACTAGCTAGAGCATACAATACTGTTGTTCCATCTTCAGGTAAGGTACTAACTGGTGGAGTTGATT CAAATGCTTTACAAAAACCAAAAAGCTTTTTTGGAGCAGCTCGTAATATCGAAAATGGTGGGTCTTTAACTATTATTGCA ACTGCATTAGTTGATACAGGTTCTAGAATGGATGAAGTGATTTTTGAGGAGTTTAAAGGAACTGGCAACTCAGAAATTGT ATTAGATAGAAAGATATCTGATAAAAGAATCTATCCAGCAATTGACATTAATAAATCTGGCACTAGAAAAGAGGAGCTGT TAGTTGGTAAATCAGAATTATCAAAAATGTGGATGCTTAGAAGAATCATTCATCAAATGGGTGCTGTGGATGCTATGGAA TTTTTACTTGATAAACTTAAAAACACTAAATCTAATAGTGAATTCTTTGATTTGATGAATTCATAA
Upstream 100 bases:
>100_bases TTAAGTTTACTATACACCTTAATTATCAGTTTAATTAATATTTCATACTAGAAAGCTAATGCATTTATACCAAACTCAAT ATAATCTTTAATAATATATT
Downstream 100 bases:
>100_bases GAAACATAAGATTAGGATAAGTAAATAAAAGAAAAAGAATATGATATAAGATTGGGATTAAGTTTAGATATAGAATAACT TACAACAGAAGATATTATAT
Product: transcription termination factor Rho
Products: NA
Alternate protein names: ATP-dependent helicase Rho [H]
Number of amino acids: Translated: 501; Mature: 500
Protein sequence:
>501_residues MTTEKEHRIKNILKPVSNNNPANSEAADSSVEITAHLNEPKKKSHEALQCYAESKEHRIKKTSKPVSNNNPVNSEAAGSS VEITVHLNELKKKSPEALQCYAESLAIENASSLTKNELISAILKMVVERNGIVIEEGVIEILNGGFGFLRSPEVNYLSGA GDIYVSLSQIKRCELRTGDTVEGQIRAPKSGERYFALLKVLKVNGEDIKKSIQRLHFDDLVALYPEEKISFEVDLDYKNL STRVMELVSPMGKGQRALIVAPPRTGKTILLQNIAHSIATNHPEIYLIVLLIGERPEEVTDMIRSVKGEVVSSTFDEPAV RHTQLAEIVIEKAKRLVEHKRDVVILLDSITRLARAYNTVVPSSGKVLTGGVDSNALQKPKSFFGAARNIENGGSLTIIA TALVDTGSRMDEVIFEEFKGTGNSEIVLDRKISDKRIYPAIDINKSGTRKEELLVGKSELSKMWMLRRIIHQMGAVDAME FLLDKLKNTKSNSEFFDLMNS
Sequences:
>Translated_501_residues MTTEKEHRIKNILKPVSNNNPANSEAADSSVEITAHLNEPKKKSHEALQCYAESKEHRIKKTSKPVSNNNPVNSEAAGSS VEITVHLNELKKKSPEALQCYAESLAIENASSLTKNELISAILKMVVERNGIVIEEGVIEILNGGFGFLRSPEVNYLSGA GDIYVSLSQIKRCELRTGDTVEGQIRAPKSGERYFALLKVLKVNGEDIKKSIQRLHFDDLVALYPEEKISFEVDLDYKNL STRVMELVSPMGKGQRALIVAPPRTGKTILLQNIAHSIATNHPEIYLIVLLIGERPEEVTDMIRSVKGEVVSSTFDEPAV RHTQLAEIVIEKAKRLVEHKRDVVILLDSITRLARAYNTVVPSSGKVLTGGVDSNALQKPKSFFGAARNIENGGSLTIIA TALVDTGSRMDEVIFEEFKGTGNSEIVLDRKISDKRIYPAIDINKSGTRKEELLVGKSELSKMWMLRRIIHQMGAVDAME FLLDKLKNTKSNSEFFDLMNS >Mature_500_residues TTEKEHRIKNILKPVSNNNPANSEAADSSVEITAHLNEPKKKSHEALQCYAESKEHRIKKTSKPVSNNNPVNSEAAGSSV EITVHLNELKKKSPEALQCYAESLAIENASSLTKNELISAILKMVVERNGIVIEEGVIEILNGGFGFLRSPEVNYLSGAG DIYVSLSQIKRCELRTGDTVEGQIRAPKSGERYFALLKVLKVNGEDIKKSIQRLHFDDLVALYPEEKISFEVDLDYKNLS TRVMELVSPMGKGQRALIVAPPRTGKTILLQNIAHSIATNHPEIYLIVLLIGERPEEVTDMIRSVKGEVVSSTFDEPAVR HTQLAEIVIEKAKRLVEHKRDVVILLDSITRLARAYNTVVPSSGKVLTGGVDSNALQKPKSFFGAARNIENGGSLTIIAT ALVDTGSRMDEVIFEEFKGTGNSEIVLDRKISDKRIYPAIDINKSGTRKEELLVGKSELSKMWMLRRIIHQMGAVDAMEF LLDKLKNTKSNSEFFDLMNS
Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]
COG id: COG1158
COG function: function code K; Transcription termination factor
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the Rho family [H]
Homologues:
Organism=Escherichia coli, GI1790217, Length=416, Percent_Identity=62.0192307692308, Blast_Score=528, Evalue=1e-151,
Paralogues:
None
Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000194 - InterPro: IPR003593 - InterPro: IPR011129 - InterPro: IPR012340 - InterPro: IPR016027 - InterPro: IPR011112 - InterPro: IPR011113 - InterPro: IPR004665 [H]
Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]
EC number: NA
Molecular weight: Translated: 55545; Mature: 55414
Theoretical pI: Translated: 7.73; Mature: 7.73
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTEKEHRIKNILKPVSNNNPANSEAADSSVEITAHLNEPKKKSHEALQCYAESKEHRIK CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH KTSKPVSNNNPVNSEAAGSSVEITVHLNELKKKSPEALQCYAESLAIENASSLTKNELIS HHCCCCCCCCCCCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH AILKMVVERNGIVIEEGVIEILNGGFGFLRSPEVNYLSGAGDIYVSLSQIKRCELRTGDT HHHHHHHHCCCEEEECCHHHHHCCCCCCCCCCCCCEECCCCCEEEEHHHHHHHHCCCCCC VEGQIRAPKSGERYFALLKVLKVNGEDIKKSIQRLHFDDLVALYPEEKISFEVDLDYKNL CCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCCCCCEEEEEECCHHHH STRVMELVSPMGKGQRALIVAPPRTGKTILLQNIAHSIATNHPEIYLIVLLIGERPEEVT HHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHH DMIRSVKGEVVSSTFDEPAVRHTQLAEIVIEKAKRLVEHKRDVVILLDSITRLARAYNTV HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHC VPSSGKVLTGGVDSNALQKPKSFFGAARNIENGGSLTIIATALVDTGSRMDEVIFEEFKG CCCCCCEEECCCCCHHHHCHHHHHHHHCCCCCCCCEEEEEEEHHCCCCHHHHHHHHHHCC TGNSEIVLDRKISDKRIYPAIDINKSGTRKEELLVGKSELSKMWMLRRIIHQMGAVDAME CCCCEEEEECCCCCCCCCCEEECCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHH FLLDKLKNTKSNSEFFDLMNS HHHHHHHCCCCCCHHHHHHCC >Mature Secondary Structure TTEKEHRIKNILKPVSNNNPANSEAADSSVEITAHLNEPKKKSHEALQCYAESKEHRIK CCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH KTSKPVSNNNPVNSEAAGSSVEITVHLNELKKKSPEALQCYAESLAIENASSLTKNELIS HHCCCCCCCCCCCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH AILKMVVERNGIVIEEGVIEILNGGFGFLRSPEVNYLSGAGDIYVSLSQIKRCELRTGDT HHHHHHHHCCCEEEECCHHHHHCCCCCCCCCCCCCEECCCCCEEEEHHHHHHHHCCCCCC VEGQIRAPKSGERYFALLKVLKVNGEDIKKSIQRLHFDDLVALYPEEKISFEVDLDYKNL CCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCCCCCEEEEEECCHHHH STRVMELVSPMGKGQRALIVAPPRTGKTILLQNIAHSIATNHPEIYLIVLLIGERPEEVT HHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHH DMIRSVKGEVVSSTFDEPAVRHTQLAEIVIEKAKRLVEHKRDVVILLDSITRLARAYNTV HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHC VPSSGKVLTGGVDSNALQKPKSFFGAARNIENGGSLTIIATALVDTGSRMDEVIFEEFKG CCCCCCEEECCCCCHHHHCHHHHHHHHCCCCCCCCEEEEEEEHHCCCCHHHHHHHHHHCC TGNSEIVLDRKISDKRIYPAIDINKSGTRKEELLVGKSELSKMWMLRRIIHQMGAVDAME CCCCEEEEECCCCCCCCCCEEECCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHH FLLDKLKNTKSNSEFFDLMNS HHHHHHHCCCCCCHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11557893 [H]