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The map label for this gene is 189183138

Identifier: 189183138

GI number: 189183138

Start: 219424

End: 220932

Strand: Direct

Name: 189183138

Synonym: OTT_0231

Alternate gene names: NA

Gene position: 219424-220932 (Clockwise)

Preceding gene: 189183137

Following gene: 189183139

Centisome position: 10.92

GC content: 26.97

Gene sequence:

>1509_bases
ATGAAATTTGTAAAATATATAACAGCTATTTTATTATTAACACTGTTAAATACAACCATTGCATCAAAACGAAACAACAA
TCAACCTGTACAACAGAAATTAATTCATGATAAAGCTATATTAGCAGAAAAACATTTTTATGTTGGAATTTCATTTCTTA
AGTTAAACAAATATCAAGAAGCGATAGAAAATTTTGATTTAGCTATTAAGTATAATCCTAATTGTGCAGAAGCTTATTAT
AATAAAGGAATTTGTTTAGATAAATTAGGACAATTGCAGAAAGCAATAGAAAATTTTGATTTAACTATTAAGTATAAGTC
CAATTGCGAAGAAGCATACCTTAGTAAAGGAGTTAGTTTAGGTAAATTAGGACAATTACAGAAAGCGATAGAAAATTTCG
ATTTAGCTATTAAGCATAATATTAATTATGAAACAGCATACCTTAATAAAGGAATTTGTTTGTATAAATTAGGACAATAT
CATGAGGCAATAGAATGTTGTAATCTAGCTATTAAATATGAGCCCTATAATCCAGATGCTTATCATAGTAAAGGAATGTG
TTTAGACAAATTAGGACAATATCATGAGGCAATAGAAAATTTTGATTTAGCTATTAAATATGAGCCCTATAATCCAGATA
CTTATAATAATAAAGGAGTTTGTGTAGATAAATTAGGACAACATCAAGAGGCAATAAAAATTTTTAATTTAGCTATTAAG
TATAAACCTAATTGTGAAGAAGCATACCTTAATAAAGGAATGTGTTTGTATCAATTAGAACAATATAAAGAGGCAATAGA
AAATTTTGATTTAGCTATTAAGTATAAGTCAAACTATGTAGGAGCATACCTTAATAAAGGAGCTTGTTTAAGCAAATTGG
AACAACATCAAGAAGCAATAGAAAATTTTGATTTAGCTATTAAATATGAGCTCTGTAATCCAGATACTTATTATAATAAA
GGCGCTTGTTTATATGAATTAAGGCAATATCAGGAAGCAGTAGAAAATTTTGATTTAGCTATTAAGTATAATCCTAATTT
TGAAAAAGCATACCTTAGTAAAGGCGCTTGTTTATATGAATTAAGGCAATATCAGGAAGCAATAGAATGTTGTAATCTAG
CTATTAAGTATAATCCTAATGATGCAGAGGCTTATTATAATAAAGGAGTTTGTTTATTCAAATTAGGACAACATCAAGCA
GCGGTAGAAAATTATGATTTAGCTATTAAGTATAACCCTAATTATGTAGACGCTTATTATAATAAAGGACTTTGTTTAAG
TAAATTAGGACAAGCTCAAGAAGCAGTAGAAAATTTTAATTTAGCTATTAAGTATAATCCTAATGATGCAGAGGCTTATT
ATAATAAAGGACTTTGTTTATATGAATTAAGGCAATATCAGGCAGCAATAGCAAATTTTGATTTAGCTATTAAATATGAT
CCTAATAATGGAACGTTATACCAGTTAATAAATATACTCAAACAAGAAATTGCAGGTATTAAAAAGTAA

Upstream 100 bases:

>100_bases
AAAAAAAATATAAAAGAAAGAATAATTACAATACCTCTAATTCAGTAATTATTTGGTGTTCAGTAGCTAATCAAAAATTT
AAAGGGTAATTAATAATCAT

Downstream 100 bases:

>100_bases
TCTTGATTTTTAACACAAGATCTGTAATAAGCAGGTATTATAAGGCATTATCATGATTTATTTGTGATACAAATTGTTAT
AAAATAGTCATAAGATATAA

Product: TPR repeat-containing protein 03

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MKFVKYITAILLLTLLNTTIASKRNNNQPVQQKLIHDKAILAEKHFYVGISFLKLNKYQEAIENFDLAIKYNPNCAEAYY
NKGICLDKLGQLQKAIENFDLTIKYKSNCEEAYLSKGVSLGKLGQLQKAIENFDLAIKHNINYETAYLNKGICLYKLGQY
HEAIECCNLAIKYEPYNPDAYHSKGMCLDKLGQYHEAIENFDLAIKYEPYNPDTYNNKGVCVDKLGQHQEAIKIFNLAIK
YKPNCEEAYLNKGMCLYQLEQYKEAIENFDLAIKYKSNYVGAYLNKGACLSKLEQHQEAIENFDLAIKYELCNPDTYYNK
GACLYELRQYQEAVENFDLAIKYNPNFEKAYLSKGACLYELRQYQEAIECCNLAIKYNPNDAEAYYNKGVCLFKLGQHQA
AVENYDLAIKYNPNYVDAYYNKGLCLSKLGQAQEAVENFNLAIKYNPNDAEAYYNKGLCLYELRQYQAAIANFDLAIKYD
PNNGTLYQLINILKQEIAGIKK

Sequences:

>Translated_502_residues
MKFVKYITAILLLTLLNTTIASKRNNNQPVQQKLIHDKAILAEKHFYVGISFLKLNKYQEAIENFDLAIKYNPNCAEAYY
NKGICLDKLGQLQKAIENFDLTIKYKSNCEEAYLSKGVSLGKLGQLQKAIENFDLAIKHNINYETAYLNKGICLYKLGQY
HEAIECCNLAIKYEPYNPDAYHSKGMCLDKLGQYHEAIENFDLAIKYEPYNPDTYNNKGVCVDKLGQHQEAIKIFNLAIK
YKPNCEEAYLNKGMCLYQLEQYKEAIENFDLAIKYKSNYVGAYLNKGACLSKLEQHQEAIENFDLAIKYELCNPDTYYNK
GACLYELRQYQEAVENFDLAIKYNPNFEKAYLSKGACLYELRQYQEAIECCNLAIKYNPNDAEAYYNKGVCLFKLGQHQA
AVENYDLAIKYNPNYVDAYYNKGLCLSKLGQAQEAVENFNLAIKYNPNDAEAYYNKGLCLYELRQYQAAIANFDLAIKYD
PNNGTLYQLINILKQEIAGIKK
>Mature_502_residues
MKFVKYITAILLLTLLNTTIASKRNNNQPVQQKLIHDKAILAEKHFYVGISFLKLNKYQEAIENFDLAIKYNPNCAEAYY
NKGICLDKLGQLQKAIENFDLTIKYKSNCEEAYLSKGVSLGKLGQLQKAIENFDLAIKHNINYETAYLNKGICLYKLGQY
HEAIECCNLAIKYEPYNPDAYHSKGMCLDKLGQYHEAIENFDLAIKYEPYNPDTYNNKGVCVDKLGQHQEAIKIFNLAIK
YKPNCEEAYLNKGMCLYQLEQYKEAIENFDLAIKYKSNYVGAYLNKGACLSKLEQHQEAIENFDLAIKYELCNPDTYYNK
GACLYELRQYQEAVENFDLAIKYNPNFEKAYLSKGACLYELRQYQEAIECCNLAIKYNPNDAEAYYNKGVCLFKLGQHQA
AVENYDLAIKYNPNYVDAYYNKGLCLSKLGQAQEAVENFNLAIKYNPNDAEAYYNKGLCLYELRQYQAAIANFDLAIKYD
PNNGTLYQLINILKQEIAGIKK

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=394, Percent_Identity=27.6649746192893, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI32307148, Length=394, Percent_Identity=27.6649746192893, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI310123097, Length=434, Percent_Identity=23.7327188940092, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI310110582, Length=491, Percent_Identity=23.6252545824847, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI310131789, Length=434, Percent_Identity=23.7327188940092, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI83415184, Length=432, Percent_Identity=23.3796296296296, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI301336134, Length=430, Percent_Identity=23.2558139534884, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI170784867, Length=264, Percent_Identity=25, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI118766330, Length=288, Percent_Identity=23.2638888888889, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI118766328, Length=288, Percent_Identity=23.2638888888889, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI296531396, Length=200, Percent_Identity=29, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI224809432, Length=243, Percent_Identity=24.6913580246914, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI221219056, Length=333, Percent_Identity=23.1231231231231, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI262206280, Length=346, Percent_Identity=22.5433526011561, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI25952122, Length=312, Percent_Identity=25.9615384615385, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=393, Percent_Identity=27.4809160305344, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI115532690, Length=393, Percent_Identity=27.4809160305344, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25147174, Length=276, Percent_Identity=20.6521739130435, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17551190, Length=334, Percent_Identity=20.059880239521, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6319387, Length=304, Percent_Identity=25.6578947368421, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17647755, Length=394, Percent_Identity=27.1573604060914, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24585827, Length=394, Percent_Identity=27.1573604060914, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24585829, Length=394, Percent_Identity=27.1573604060914, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI19920486, Length=331, Percent_Identity=26.2839879154079, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI161076610, Length=331, Percent_Identity=26.2839879154079, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24647123, Length=252, Percent_Identity=25.3968253968254, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17137540, Length=425, Percent_Identity=20.2352941176471, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24656717, Length=331, Percent_Identity=25.3776435045317, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18110006, Length=331, Percent_Identity=25.3776435045317, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24659892, Length=299, Percent_Identity=22.4080267558528, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24584630, Length=340, Percent_Identity=22.3529411764706, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 57799; Mature: 57799

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVKYITAILLLTLLNTTIASKRNNNQPVQQKLIHDKAILAEKHFYVGISFLKLNKYQE
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEEHHHHHH
AIENFDLAIKYNPNCAEAYYNKGICLDKLGQLQKAIENFDLTIKYKSNCEEAYLSKGVSL
HHCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCC
GKLGQLQKAIENFDLAIKHNINYETAYLNKGICLYKLGQYHEAIECCNLAIKYEPYNPDA
CHHHHHHHHHHCCCEEEEECCCEEEEEECCCEEEEEHHHHHHHHHHCCEEEEECCCCCCC
YHSKGMCLDKLGQYHEAIENFDLAIKYEPYNPDTYNNKGVCVDKLGQHQEAIKIFNLAIK
CCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHCCHHHHHHHEEEEEE
YKPNCEEAYLNKGMCLYQLEQYKEAIENFDLAIKYKSNYVGAYLNKGACLSKLEQHQEAI
ECCCCHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHH
ENFDLAIKYELCNPDTYYNKGACLYELRQYQEAVENFDLAIKYNPNFEKAYLSKGACLYE
HCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCCHHHHH
LRQYQEAIECCNLAIKYNPNDAEAYYNKGVCLFKLGQHQAAVENYDLAIKYNPNYVDAYY
HHHHHHHHHHCCEEEEECCCCHHHHHCCCEEEEEECCCHHHHCCCEEEEEECCCEEEHHH
NKGLCLSKLGQAQEAVENFNLAIKYNPNDAEAYYNKGLCLYELRQYQAAIANFDLAIKYD
CCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEE
PNNGTLYQLINILKQEIAGIKK
CCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFVKYITAILLLTLLNTTIASKRNNNQPVQQKLIHDKAILAEKHFYVGISFLKLNKYQE
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEEHHHHHH
AIENFDLAIKYNPNCAEAYYNKGICLDKLGQLQKAIENFDLTIKYKSNCEEAYLSKGVSL
HHCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCC
GKLGQLQKAIENFDLAIKHNINYETAYLNKGICLYKLGQYHEAIECCNLAIKYEPYNPDA
CHHHHHHHHHHCCCEEEEECCCEEEEEECCCEEEEEHHHHHHHHHHCCEEEEECCCCCCC
YHSKGMCLDKLGQYHEAIENFDLAIKYEPYNPDTYNNKGVCVDKLGQHQEAIKIFNLAIK
CCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHCCHHHHHHHEEEEEE
YKPNCEEAYLNKGMCLYQLEQYKEAIENFDLAIKYKSNYVGAYLNKGACLSKLEQHQEAI
ECCCCHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHH
ENFDLAIKYELCNPDTYYNKGACLYELRQYQEAVENFDLAIKYNPNFEKAYLSKGACLYE
HCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCCHHHHH
LRQYQEAIECCNLAIKYNPNDAEAYYNKGVCLFKLGQHQAAVENYDLAIKYNPNYVDAYY
HHHHHHHHHHCCEEEEECCCCHHHHHCCCEEEEEECCCHHHHCCCEEEEEECCCEEEHHH
NKGLCLSKLGQAQEAVENFNLAIKYNPNDAEAYYNKGLCLYELRQYQAAIANFDLAIKYD
CCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEE
PNNGTLYQLINILKQEIAGIKK
CCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]