| Definition | Treponema pallidum subsp. pallidum SS14, complete genome. |
|---|---|
| Accession | NC_010741 |
| Length | 1,139,457 |
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The map label for this gene is lysK [H]
Identifier: 189025869
GI number: 189025869
Start: 706897
End: 708483
Strand: Reverse
Name: lysK [H]
Synonym: TPASS_0644
Alternate gene names: 189025869
Gene position: 708483-706897 (Counterclockwise)
Preceding gene: 189025870
Following gene: 189025866
Centisome position: 62.18
GC content: 47.39
Gene sequence:
>1587_bases ATGAGTATCTGTGAAAAGTCACTTCATTGGGCTGACAAGGTTGCGCACAAGATTATCAAGGAATGTGCTGACTGTGATCA ATACACCTGTGCATCGGGGATTACCCCCTCAGGAACGGTACATATTGGTAATTTCAGAGAGATTATTTCCGTTGACCTTG TAGTGCGGGCCCTGCGTGACCAGGGGAAATCAGTGCGCTTTGTACATTCGTGGGACGATTATGACGTTTTTCGTAGGATT CCCGACAATGTACCTGCTCAAGATGAATTGAAGCAGTATATTCGCATGCCTATCACTTCAGTTCCTGATCCCTTTCAGCA GGAAGATAGCTACGCGCGGCACCATGAGCGGGAAATTGAATCGGCGCTCCCGGAGGTAGGTATTTATCCTGAATACGTTT ATCAGTCAAAGCAATACCAGGCGGGGGTATACGCACAGGAAATAAAGATTGCGCTCGACAATCGGCACCGTATTCAAGCG ATTTTAAACGAATATCGAGATGAGCAGCATAAAATCAGTGGAACGTATTGGCCCGTATCGGTGTTTTGTACAGCGTGCCA TAAAGACTGCACCACGGTTGATGCGTGGGATAGCCACTGGTGTCTTCAGTATCATTGCGAGTGTGGGCATGGGGAGCAGG TGGATTTACGCCAGACGTCTGCGGTAAAACTTAGCTGGCGCGTTGATTGGGCTATGCGGTGGAGTAAGGAGCATGTGGTA TTTGAGCCTGCAGGGAAGGATCATCATTCTCAGGGAGGTTCTTTTGACACTGCGCGTTTAATTTCTGATCACATTTATCA CTGGCCTGCGCCTGTTTCTTTTCGTTATGATTTTATTGGATTAAAAGGTTTGCCTGGGAAGATGTCTTCGTCCGCGGGAA AAGTGGTTGGGCTGCGTGATGTGCTTGAAGTATATCAGCCTGAAGTATTGCGATACCTTTTTGTTTCCACACGTCCAAAT ACCGAGTTTTCCATTAGTTTTGATCTTGATGTTCTTAAGATATACGAGGATTACGATAAAAGTGAGCGTGTTGCGTGGGG AATACATGCGGCAAAAAGCGAACACGAATTTATGCGGCATAAAAGGATCTACGAATTGTCACAAGTGCGTGGTATGCCGC CGTGCATTTCGTACCAGGTACCATTCCGGCATGTATGCAATATATTGCAAATTAATTCGGGAGATATTTCTGCAGTGCTC GCGTTTTTCTCTGATATACACAAAGATCAGATAGAGCGCTTTGTGCGCCGTTGCCAATGTGCGTGGAACTGGATCCGGGA CGCTGGTGCACCCGATGACTTTAAATTTACCCTGAAAGAAGATGGTGTGCGCGTGCCGCTCTCTGCAGAGATAACTGAAG CACTGAGACTCATTCGTGATACGCTTGTGCCACGCACTGACGTACTCAGCGAAAAGGAACTTTCTGCTGAGTTGTATGCG GTTGCCAGACAGATACCTGTTGGCTCGAAGGAACTGTTCACTGCACTATACCAGGTACTGATCGGAAAGAATCAGGGGCC ACGGCTTGCGGGTTTCATGAAAGTCATCGGTACACAGCGTTTGCACCGCATGCTTAGCGTATACTAA
Upstream 100 bases:
>100_bases TATTCGGCACTGCCACCTATGTGGAAGTGTAGGATGTGCGCGTGGGAAGTGCGTACTGGCTTGGCTTTAAAAATATTTTG CGTACCTGTAAGGAAGGATC
Downstream 100 bases:
>100_bases AACAGCTCCTGGGAACAGTCAGTGCTCGATGCCTGTATCTCCTGTATTAATTTTTTTATGGTGGGGCTTTGTGCATGATT TACACAGTGTCCGTTTTGTT
Product: lysyl-tRNA synthetase
Products: NA
Alternate protein names: Lysine--tRNA ligase; LysRS [H]
Number of amino acids: Translated: 528; Mature: 527
Protein sequence:
>528_residues MSICEKSLHWADKVAHKIIKECADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRDQGKSVRFVHSWDDYDVFRRI PDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIESALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQA ILNEYRDEQHKISGTYWPVSVFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVV FEPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRDVLEVYQPEVLRYLFVSTRPN TEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRHKRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVL AFFSDIHKDQIERFVRRCQCAWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYA VARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY
Sequences:
>Translated_528_residues MSICEKSLHWADKVAHKIIKECADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRDQGKSVRFVHSWDDYDVFRRI PDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIESALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQA ILNEYRDEQHKISGTYWPVSVFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVV FEPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRDVLEVYQPEVLRYLFVSTRPN TEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRHKRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVL AFFSDIHKDQIERFVRRCQCAWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYA VARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY >Mature_527_residues SICEKSLHWADKVAHKIIKECADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRDQGKSVRFVHSWDDYDVFRRIP DNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIESALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQAI LNEYRDEQHKISGTYWPVSVFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVVF EPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRDVLEVYQPEVLRYLFVSTRPNT EFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRHKRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVLA FFSDIHKDQIERFVRRCQCAWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYAV ARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY
Specific function: Unknown
COG id: COG1384
COG function: function code J; Lysyl-tRNA synthetase (class I)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008925 - InterPro: IPR020751 - InterPro: IPR001412 - InterPro: IPR002904 - InterPro: IPR020754 - InterPro: IPR020756 - InterPro: IPR014729 [H]
Pfam domain/function: PF01921 tRNA-synt_1f [H]
EC number: =6.1.1.6 [H]
Molecular weight: Translated: 60849; Mature: 60718
Theoretical pI: Translated: 6.92; Mature: 6.92
Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS00178 AA_TRNA_LIGASE_I
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.7 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 2.7 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSICEKSLHWADKVAHKIIKECADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRD CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHH QGKSVRFVHSWDDYDVFRRIPDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIE CCCEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH SALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQAILNEYRDEQHKISGTYWPVS HHCCCCCCCHHHHHCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHCCHHHHCCCCCCHHH VFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVV HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCEEEEEEEEEEHEEECCCEEE FEPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRD ECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCEECHHH VLEVYQPEVLRYLFVSTRPNTEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRH HHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHH KRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVLAFFSDIHKDQIERFVRRCQC HHHHHHHHHCCCCCCEECCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH AWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYA HHHHHHCCCCCCCEEEEEECCCEECCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHH VARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY HHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure SICEKSLHWADKVAHKIIKECADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRD CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHH QGKSVRFVHSWDDYDVFRRIPDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIE CCCEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH SALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQAILNEYRDEQHKISGTYWPVS HHCCCCCCCHHHHHCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHCCHHHHCCCCCCHHH VFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVV HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCEEEEEEEEEEHEEECCCEEE FEPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRD ECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCEECHHH VLEVYQPEVLRYLFVSTRPNTEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRH HHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHH KRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVLAFFSDIHKDQIERFVRRCQC HHHHHHHHHCCCCCCEECCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH AWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYA HHHHHHCCCCCCCEEEEEECCCEECCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHH VARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY HHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9665876 [H]