Click here to switch to the map view.

The map label for this gene is ahpC [H]

Identifier: 189025739

GI number: 189025739

Start: 545826

End: 546392

Strand: Direct

Name: ahpC [H]

Synonym: TPASS_0509

Alternate gene names: 189025739

Gene position: 545826-546392 (Clockwise)

Preceding gene: 189025738

Following gene: 189025741

Centisome position: 47.9

GC content: 51.32

Gene sequence:

>567_bases
ATGGAGAGTCTCATAGGCAAGAGGGTTATAGACTTTAAGCTTCCTGCGTATGTCGGGGGGAAGTTTACGGAGGTCTCTAA
CGCATCCATTAAGGGTAGCTGGGCGGTGTTTATGTTTTACCCGGCCGACTTCACCTTTGTGTGCCCCACCGAGCTTGCGG
ATCTCGCGCGCGTATATCCGTCTTTTGTGGAGATTGGTTGTAAGGTATATTCGGTTTCTACGGACAGTGAGTACGTGCAC
AAGGCATGGGCGGATGCGACAGACACGATAAAGAATCTGCCCTACGAGATGATTTCTGACAAGGCGGGAAAGCTTGCGGG
TTTCTTTGGAGTGTTGTTGCCAGACACTTGGCATGCGCTGCGGGGTACGTTCGTGGTCGATCCTGAAGGCCTTGTGAAAG
CTTTCGAGGTACACGACATGGGTATTGGGCGCGATGCGGATGAGCTTTTGCGCAAGGTTCAGTCAGCACAGTTTGTGGCT
AAGCATGGGGATCAGGTTTGTCCTGCTCGTTGGAAGCCTGGAGCAAAGACGTTGAAGCCTGGTATTGATTTAATCGGTAA
GATTTAG

Upstream 100 bases:

>100_bases
GTGATGGTGTGGTGACCCGGGGGATACGTGTGAAAGACTTTACTTTTCCCCGTTTGTTTCCTATAGTTTGCGCTAGAGTG
CGAACGTTTGGGAGGTTGCT

Downstream 100 bases:

>100_bases
TGCGGCCCGGAGGGCGCGCGTCGCCCTCCCCGCCTGTTCTTTTTCTGTTTTTGCTGCGTATAATGTGTGTTCTGTCTACT
TATCCAGATACCTAAGTCTA

Product: alkyl hydroperoxide reductase

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; General stress protein 22; Peroxiredoxin; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MESLIGKRVIDFKLPAYVGGKFTEVSNASIKGSWAVFMFYPADFTFVCPTELADLARVYPSFVEIGCKVYSVSTDSEYVH
KAWADATDTIKNLPYEMISDKAGKLAGFFGVLLPDTWHALRGTFVVDPEGLVKAFEVHDMGIGRDADELLRKVQSAQFVA
KHGDQVCPARWKPGAKTLKPGIDLIGKI

Sequences:

>Translated_188_residues
MESLIGKRVIDFKLPAYVGGKFTEVSNASIKGSWAVFMFYPADFTFVCPTELADLARVYPSFVEIGCKVYSVSTDSEYVH
KAWADATDTIKNLPYEMISDKAGKLAGFFGVLLPDTWHALRGTFVVDPEGLVKAFEVHDMGIGRDADELLRKVQSAQFVA
KHGDQVCPARWKPGAKTLKPGIDLIGKI
>Mature_188_residues
MESLIGKRVIDFKLPAYVGGKFTEVSNASIKGSWAVFMFYPADFTFVCPTELADLARVYPSFVEIGCKVYSVSTDSEYVH
KAWADATDTIKNLPYEMISDKAGKLAGFFGVLLPDTWHALRGTFVVDPEGLVKAFEVHDMGIGRDADELLRKVQSAQFVA
KHGDQVCPARWKPGAKTLKPGIDLIGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=41.7582417582418, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI32483377, Length=172, Percent_Identity=39.5348837209302, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI5802974, Length=172, Percent_Identity=39.5348837209302, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI4505591, Length=184, Percent_Identity=39.6739130434783, Blast_Score=138, Evalue=3e-33,
Organism=Homo sapiens, GI32455266, Length=184, Percent_Identity=39.6739130434783, Blast_Score=138, Evalue=3e-33,
Organism=Homo sapiens, GI32455264, Length=184, Percent_Identity=39.6739130434783, Blast_Score=138, Evalue=3e-33,
Organism=Homo sapiens, GI5453549, Length=176, Percent_Identity=38.0681818181818, Blast_Score=133, Evalue=9e-32,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=46.9135802469136, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758638, Length=154, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1786822, Length=186, Percent_Identity=50, Blast_Score=199, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI193204376, Length=184, Percent_Identity=39.6739130434783, Blast_Score=140, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32565831, Length=184, Percent_Identity=39.6739130434783, Blast_Score=140, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17554494, Length=174, Percent_Identity=38.5057471264368, Blast_Score=128, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25153706, Length=158, Percent_Identity=28.4810126582279, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=188, Percent_Identity=37.7659574468085, Blast_Score=126, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320661, Length=192, Percent_Identity=35.9375, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319407, Length=159, Percent_Identity=27.0440251572327, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357347, Length=180, Percent_Identity=41.6666666666667, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI17738015, Length=178, Percent_Identity=38.2022471910112, Blast_Score=140, Evalue=6e-34,
Organism=Drosophila melanogaster, GI17157991, Length=166, Percent_Identity=38.5542168674699, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24641739, Length=166, Percent_Identity=38.5542168674699, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24656348, Length=183, Percent_Identity=35.5191256830601, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17864676, Length=183, Percent_Identity=35.5191256830601, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24652436, Length=158, Percent_Identity=31.6455696202532, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=31.6455696202532, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=31.6455696202532, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=32.2784810126582, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20709; Mature: 20709

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLIGKRVIDFKLPAYVGGKFTEVSNASIKGSWAVFMFYPADFTFVCPTELADLARVYP
CCCHHHCEEEEEECCHHHCCCEEECCCCEECCCEEEEEEECCCEEEECHHHHHHHHHHHH
SFVEIGCKVYSVSTDSEYVHKAWADATDTIKNLPYEMISDKAGKLAGFFGVLLPDTWHAL
HHHHHCCEEEEECCCHHHHHHHHCCHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCHHHH
RGTFVVDPEGLVKAFEVHDMGIGRDADELLRKVQSAQFVAKHGDQVCPARWKPGAKTLKP
CCCEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCC
GIDLIGKI
CHHHHCCC
>Mature Secondary Structure
MESLIGKRVIDFKLPAYVGGKFTEVSNASIKGSWAVFMFYPADFTFVCPTELADLARVYP
CCCHHHCEEEEEECCHHHCCCEEECCCCEECCCEEEEEEECCCEEEECHHHHHHHHHHHH
SFVEIGCKVYSVSTDSEYVHKAWADATDTIKNLPYEMISDKAGKLAGFFGVLLPDTWHAL
HHHHHCCEEEEECCCHHHHHHHHCCHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCHHHH
RGTFVVDPEGLVKAFEVHDMGIGRDADELLRKVQSAQFVAKHGDQVCPARWKPGAKTLKP
CCCEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCC
GIDLIGKI
CHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 8180695; 8012595 [H]