Click here to switch to the map view.

The map label for this gene is atpH

Identifier: 188587437

GI number: 188587437

Start: 3081486

End: 3082025

Strand: Reverse

Name: atpH

Synonym: Nther_2847

Alternate gene names: 188587437

Gene position: 3082025-3081486 (Counterclockwise)

Preceding gene: 188587438

Following gene: 188587436

Centisome position: 97.36

GC content: 32.96

Gene sequence:

>540_bases
ATGATAATACCAAAAAGATATGCCGAGGCTTTATTTCAATTAGCAAAAGAACGGGAAAAAATTAATGAGATAACTCAATC
TTTTAATCAATTGATTGAAAGGCTTCGGTCTAATGAGGAAGTTTTTAAACTTCTATCTTATCCTGTCGTTGATATTGCAG
AAAAAAAACAAGTTGCCGATGAGCTAACTGCAGATTTAGAGCAAGAAATACGAGATTATCTAAAAGTTTTAATTGACAAT
AAACGAACTGATGAATTAGCGGAAATTCACGATACTTTCTTAGACCTTGTTAGAACTGAAGAAAATAGAACTTTATGTGA
AGTGAAAACCCCAATACCTTTAGATGAAGATGAACTTAAAAAAATTCAAGATTTACTTGCCCAAATGTCTGAAGGAGAAG
TAGAAATTGAAACTACTACTGATGAATCTATCATTGGTGGCATAGTTGTGAGAATCGGGGACCGAGTCTTTGATTATAGC
TTAAAGGGTCAGTTAAATAGTCTCCGAGAACAACTTAAAAAGACAACTATCACAAGTTGA

Upstream 100 bases:

>100_bases
TAACCATTCAAATAACTGAAAGAGTTCTTAATGACACCATTGACAAGGATCAACAGAAAAAACTTGTGCAAAAATATCTA
AAAGAGGTAGGTAGGGTATC

Downstream 100 bases:

>100_bases
GGTGAAGGTTATGAGTATTCGTCCTGATGAAATTAGTACGGTGTTAAAAGATAAAATTGCAAATTATGAGTCTCAAGTAG
ACGTTTATGAAGTGGGCACC

Product: ATP synthase F1, delta subunit

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MIIPKRYAEALFQLAKEREKINEITQSFNQLIERLRSNEEVFKLLSYPVVDIAEKKQVADELTADLEQEIRDYLKVLIDN
KRTDELAEIHDTFLDLVRTEENRTLCEVKTPIPLDEDELKKIQDLLAQMSEGEVEIETTTDESIIGGIVVRIGDRVFDYS
LKGQLNSLREQLKKTTITS

Sequences:

>Translated_179_residues
MIIPKRYAEALFQLAKEREKINEITQSFNQLIERLRSNEEVFKLLSYPVVDIAEKKQVADELTADLEQEIRDYLKVLIDN
KRTDELAEIHDTFLDLVRTEENRTLCEVKTPIPLDEDELKKIQDLLAQMSEGEVEIETTTDESIIGGIVVRIGDRVFDYS
LKGQLNSLREQLKKTTITS
>Mature_179_residues
MIIPKRYAEALFQLAKEREKINEITQSFNQLIERLRSNEEVFKLLSYPVVDIAEKKQVADELTADLEQEIRDYLKVLIDN
KRTDELAEIHDTFLDLVRTEENRTLCEVKTPIPLDEDELKKIQDLLAQMSEGEVEIETTTDESIIGGIVVRIGDRVFDYS
LKGQLNSLREQLKKTTITS

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=172, Percent_Identity=25, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1790173, Length=175, Percent_Identity=24.5714285714286, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71984717, Length=171, Percent_Identity=22.8070175438596, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984710, Length=174, Percent_Identity=22.4137931034483, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24647054, Length=164, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_NATTJ (B2A3G5)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001918982.1
- ProteinModelPortal:   B2A3G5
- GeneID:   6316462
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_2847
- HOGENOM:   HBG668108
- OMA:   NANKDFV
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 20727; Mature: 20727

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIPKRYAEALFQLAKEREKINEITQSFNQLIERLRSNEEVFKLLSYPVVDIAEKKQVAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
ELTADLEQEIRDYLKVLIDNKRTDELAEIHDTFLDLVRTEENRTLCEVKTPIPLDEDELK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHH
KIQDLLAQMSEGEVEIETTTDESIIGGIVVRIGDRVFDYSLKGQLNSLREQLKKTTITS
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIIPKRYAEALFQLAKEREKINEITQSFNQLIERLRSNEEVFKLLSYPVVDIAEKKQVAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
ELTADLEQEIRDYLKVLIDNKRTDELAEIHDTFLDLVRTEENRTLCEVKTPIPLDEDELK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHH
KIQDLLAQMSEGEVEIETTTDESIIGGIVVRIGDRVFDYSLKGQLNSLREQLKKTTITS
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA