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The map label for this gene is fabH [H]

Identifier: 188587326

GI number: 188587326

Start: 2948058

End: 2949056

Strand: Reverse

Name: fabH [H]

Synonym: Nther_2731

Alternate gene names: 188587326

Gene position: 2949056-2948058 (Counterclockwise)

Preceding gene: 188587327

Following gene: 188587325

Centisome position: 93.16

GC content: 39.94

Gene sequence:

>999_bases
ATGAATAGCTTAGTACAAAATGCCGTGATTACAGGTACAGGCAAGTATCTTCCTCCACATCTGTACACTAATAATGATAT
TGCAGAAATATTAGGCCATCCTTTGAAGGATGGCCTTGAGACAAAACTTGGGATAAAACAGCGGTATTTTACTGGAAAAG
ATGAAAGCACTGCTGATATGGCTGTGAAAGCCGGAGAACAAGCCATAGCAAATGCGGGTTTATCCAAAGATGATATTCAG
TTATTGATTATAGCTACAGACACTCCGGAATACATCACACCGGCTACTTCCTCGGTGGTTCAAGGACGTTTAGAGACTTT
TAATGCGGGGACCTTTGACTTAAATGCTTCCTGTGCCGGATTTGTTAGTGGACTGGAAGTGGCTTCAAGGATGATACAAA
CGGGAGCTTATCGACACATATTATTAATCGGAGTTTATAATATGTCTAAATTCGTAGACAAATCAGACTCCAGTGCTCTA
CCTATTTTTGCCGATGGTGCCGGAGCCGTAGTTTTATCAGGCACCAAAAATCAGGATAGGGGTTTTATGAACGGTAAAAT
GATCGCTGATGGAACCCAGTATGATTTCCTAGGAATCTATGGGGGAGGCGCTAAAAACCCTATGAATGAAGAACGGTTGC
AAAAAGGAGAACATCAACTGACATTTTTAAAACCTTTGCCCCCTGATCGCAATATTAAAATATGGCCTCCTCTAATAGAA
GAAGTGTTACAATCCCAGGGACTTAACTATCAAGATATTGATCATATATTCTTTACTCAAATAAATAAGATGGTAATCCA
GGAAGTTATGAAAATAATAGATCTTCCCGAAGAAAAAACCACTTATATTATGGGTGAATACGGTTATACCGGTTCCTCTT
GCATTCCCATTGCCCTTAACAAAGCTTTAAGCGAAGATAAACTATCTCCAGGAGATTTAGTATTATTCGTCGGATCTGGT
GTGGGATTTGCAGTAGCCTGTGCTGCATTTAGATGGTAA

Upstream 100 bases:

>100_bases
TCGCCTGGAACTATTATCAGAAGGTGGGCACTTGTTTTTTATGGAGAGACCTGACACAGCTAATAATTTAATTCGGGAGT
TTTTGAAGGAGGATTAATCA

Downstream 100 bases:

>100_bases
TAAATTTAAAACTCGTTTATTAGCCGAGCTGCCTTGTAGTTAACTAAGGTAGCTCGGCATTTTTTATAGCTGCTTATTAA
ATTTATTTTTTATTGTTCTT

Product: Beta-ketoacyl-acyl-carrier-protein synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNSLVQNAVITGTGKYLPPHLYTNNDIAEILGHPLKDGLETKLGIKQRYFTGKDESTADMAVKAGEQAIANAGLSKDDIQ
LLIIATDTPEYITPATSSVVQGRLETFNAGTFDLNASCAGFVSGLEVASRMIQTGAYRHILLIGVYNMSKFVDKSDSSAL
PIFADGAGAVVLSGTKNQDRGFMNGKMIADGTQYDFLGIYGGGAKNPMNEERLQKGEHQLTFLKPLPPDRNIKIWPPLIE
EVLQSQGLNYQDIDHIFFTQINKMVIQEVMKIIDLPEEKTTYIMGEYGYTGSSCIPIALNKALSEDKLSPGDLVLFVGSG
VGFAVACAAFRW

Sequences:

>Translated_332_residues
MNSLVQNAVITGTGKYLPPHLYTNNDIAEILGHPLKDGLETKLGIKQRYFTGKDESTADMAVKAGEQAIANAGLSKDDIQ
LLIIATDTPEYITPATSSVVQGRLETFNAGTFDLNASCAGFVSGLEVASRMIQTGAYRHILLIGVYNMSKFVDKSDSSAL
PIFADGAGAVVLSGTKNQDRGFMNGKMIADGTQYDFLGIYGGGAKNPMNEERLQKGEHQLTFLKPLPPDRNIKIWPPLIE
EVLQSQGLNYQDIDHIFFTQINKMVIQEVMKIIDLPEEKTTYIMGEYGYTGSSCIPIALNKALSEDKLSPGDLVLFVGSG
VGFAVACAAFRW
>Mature_332_residues
MNSLVQNAVITGTGKYLPPHLYTNNDIAEILGHPLKDGLETKLGIKQRYFTGKDESTADMAVKAGEQAIANAGLSKDDIQ
LLIIATDTPEYITPATSSVVQGRLETFNAGTFDLNASCAGFVSGLEVASRMIQTGAYRHILLIGVYNMSKFVDKSDSSAL
PIFADGAGAVVLSGTKNQDRGFMNGKMIADGTQYDFLGIYGGGAKNPMNEERLQKGEHQLTFLKPLPPDRNIKIWPPLIE
EVLQSQGLNYQDIDHIFFTQINKMVIQEVMKIIDLPEEKTTYIMGEYGYTGSSCIPIALNKALSEDKLSPGDLVLFVGSG
VGFAVACAAFRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=323, Percent_Identity=27.2445820433437, Blast_Score=151, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36057; Mature: 36057

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLVQNAVITGTGKYLPPHLYTNNDIAEILGHPLKDGLETKLGIKQRYFTGKDESTADM
CCCHHCCCEEECCCCCCCCCEECCCCHHHHCCCHHHCCHHHHHCCHHHEECCCCCCHHHH
AVKAGEQAIANAGLSKDDIQLLIIATDTPEYITPATSSVVQGRLETFNAGTFDLNASCAG
HHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEECCCHHHH
FVSGLEVASRMIQTGAYRHILLIGVYNMSKFVDKSDSSALPIFADGAGAVVLSGTKNQDR
HHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHCCCCCCCCCEEECCCCEEEEECCCCCCC
GFMNGKMIADGTQYDFLGIYGGGAKNPMNEERLQKGEHQLTFLKPLPPDRNIKIWPPLIE
CCCCCEEEECCCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCCCCEEECCHHHH
EVLQSQGLNYQDIDHIFFTQINKMVIQEVMKIIDLPEEKTTYIMGEYGYTGSSCIPIALN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEHHHHH
KALSEDKLSPGDLVLFVGSGVGFAVACAAFRW
HHHHHCCCCCCCEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure
MNSLVQNAVITGTGKYLPPHLYTNNDIAEILGHPLKDGLETKLGIKQRYFTGKDESTADM
CCCHHCCCEEECCCCCCCCCEECCCCHHHHCCCHHHCCHHHHHCCHHHEECCCCCCHHHH
AVKAGEQAIANAGLSKDDIQLLIIATDTPEYITPATSSVVQGRLETFNAGTFDLNASCAG
HHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEECCCHHHH
FVSGLEVASRMIQTGAYRHILLIGVYNMSKFVDKSDSSALPIFADGAGAVVLSGTKNQDR
HHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHCCCCCCCCCEEECCCCEEEEECCCCCCC
GFMNGKMIADGTQYDFLGIYGGGAKNPMNEERLQKGEHQLTFLKPLPPDRNIKIWPPLIE
CCCCCEEEECCCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCCCCEEECCHHHH
EVLQSQGLNYQDIDHIFFTQINKMVIQEVMKIIDLPEEKTTYIMGEYGYTGSSCIPIALN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEHHHHH
KALSEDKLSPGDLVLFVGSGVGFAVACAAFRW
HHHHHCCCCCCCEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]