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The map label for this gene is ywaD [H]

Identifier: 188587014

GI number: 188587014

Start: 2571967

End: 2573721

Strand: Reverse

Name: ywaD [H]

Synonym: Nther_2406

Alternate gene names: 188587014

Gene position: 2573721-2571967 (Counterclockwise)

Preceding gene: 188587016

Following gene: 188587013

Centisome position: 81.3

GC content: 42.22

Gene sequence:

>1755_bases
ATGTTTAAAGGTGGTAAAAACCTTGGTATAACCGTATTGGCTTTGTTTATTTTACTAATAGGATCCCAGGTAGGATCCCA
AGCGGCTTTTGGGGGTGTAAGCCACATCCAAGAGACTTCAGAACTTTCTCTGGAAATCGACGGACAAGAAATTGAAACAG
ACTTGCAATTAGAACAGGGTCGAACTATGGTAGACGCTTCATCTGTAAATGAATATTTACCCCACGATCTTGACAATGAA
ATAGTACCAGTACGTGAAACCTTTGAAGAAATAGGAGCAGAAGTTAGCTGGGTAAGTGCAACTGAAACCGTAGAAATAAA
TTTAGAAGACAGAGTAGTAGAAGAACTGGAAGAAGATGTGGATGAGGAAGTGATAACAGAAGATGAAGTTTTAGGTATAG
ACCATGAGGTTTTAGAGCAGATTGACGTGGACCATGCTATGGAACATGTTGAATATCTCGCCCAGGACATTGGTACTCGC
CCTGCCGGAACTTCTGATGAACACAAAGCGGCTGACTATTTAGTTGAGTATTATCAGGATTTGGGATACGAAGTAAATAA
ACAAGAATTTCCTGTGGGATTTGCGGGCCCTGAGATGGCAGTTTTGGCTAATGTTGAAATAGAAGATGGAGAGCAGTGGT
ATGGGGAAATCGATTATGATCACGAAACCGAATACGGGGATGATTACCCCTGGGGAACGTTTGAAGAAAGGCATGGCACT
GAATGGGAGATGTGGGCTTCTCCAGGAGGTTTAATTACTGAAGGAAAACAGGAAGTCAGGGCAGAGGTTGTAAATGTCGG
TAGCGGTGATATTGAAGATATTGATGAAAAGGTAGAAGATAAAATTGTTTTAGTCGAAGGAGACTTTCGGCAGCTTGATC
CAGAGGAATTTGGTCAGATAGTGGTAGAAGTTGAAGATGAAGGTGGAGATGGAGTCATAATTTACAATAGCGGAGGCCCT
GGTGGTGCATTAGGGCAAGCATTTCCACCTTATATGAGCGAACAAGCGAATATACCAGTTCTAGGAGCTTCATACATTCA
CGGAATATGGCTTGAGGAAATGGTCGCCAATTCTGATGATGGTGTTGAACTCACTATCGATACAGTCGTCAAAGAAGATT
TAACTTCTTATAATGTAGAAGCTACTAAATCTGCAGATGATGAAAATGCTCCCATAATAGCTGTGACAGGTCACTATGAT
AGTGTGGTTTCAGCTCCAGGGGCCAATGACAATGCTTCGGGTACGGCAGCTACCATGGAGATGGCTCGGGTATTTAAAGA
ATACGATGGCGATGTGGAGCTACGATTTATTAACTTTGGGGCTGAAGAAGTTGGGCTAGTAGGTTCCCGGTATTATGTTG
AACAGTTGTCCCAGGACGAACAGGAGAGATTCAAAGGAGTTTATAATCCTGATATGGTGGCTACCAGTGATCCATATATA
GAGCATTTATTTGCCCAAACAGTAGACGGTGAACCAAACTTGGTTACTGATTCCATGAAGGAAGCAGATAAAGCCCTGGG
TTATGAAGAAGTTGCCCAAGGTCAATTTTCTGCCAGTGATCACCTTCCTTTCCATGAAGCGGGTATTCCAGCAGCTTTGT
TTATCCACATGTCCGGTGAAGGGACTCAAGAAGATTTTTATACGGAACCAGTATACCATACCCCTCTAGATACTGTAGAA
GATAATATCTGTGAAGACCGTTATGAAAAAGCATTGGAGATAATTGGAACAGCAGTCTTGGATGTTATTAATTAA

Upstream 100 bases:

>100_bases
ATAGTGTTTTTAAGATAGAAGTGATTAGTCAACTTGTCATATTTTTAACTCTAGTTACTAAGTTATAGGTGGACAATTTT
TTTACGAAAGGAGTTTTTCA

Downstream 100 bases:

>100_bases
CAATATAAACGTATATTAGATATTTTCTAAGATACTGTGAAAGCCAGCGGAAAACTGCCGCTGGCTTTGTTTTTTAAAGA
TTCTGAGCTTTTTTGTACTT

Product: peptidase M28

Products: NA

Alternate protein names: Arginyl aminopeptidase; BSAP; Leucyl aminopeptidase [H]

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MFKGGKNLGITVLALFILLIGSQVGSQAAFGGVSHIQETSELSLEIDGQEIETDLQLEQGRTMVDASSVNEYLPHDLDNE
IVPVRETFEEIGAEVSWVSATETVEINLEDRVVEELEEDVDEEVITEDEVLGIDHEVLEQIDVDHAMEHVEYLAQDIGTR
PAGTSDEHKAADYLVEYYQDLGYEVNKQEFPVGFAGPEMAVLANVEIEDGEQWYGEIDYDHETEYGDDYPWGTFEERHGT
EWEMWASPGGLITEGKQEVRAEVVNVGSGDIEDIDEKVEDKIVLVEGDFRQLDPEEFGQIVVEVEDEGGDGVIIYNSGGP
GGALGQAFPPYMSEQANIPVLGASYIHGIWLEEMVANSDDGVELTIDTVVKEDLTSYNVEATKSADDENAPIIAVTGHYD
SVVSAPGANDNASGTAATMEMARVFKEYDGDVELRFINFGAEEVGLVGSRYYVEQLSQDEQERFKGVYNPDMVATSDPYI
EHLFAQTVDGEPNLVTDSMKEADKALGYEEVAQGQFSASDHLPFHEAGIPAALFIHMSGEGTQEDFYTEPVYHTPLDTVE
DNICEDRYEKALEIIGTAVLDVIN

Sequences:

>Translated_584_residues
MFKGGKNLGITVLALFILLIGSQVGSQAAFGGVSHIQETSELSLEIDGQEIETDLQLEQGRTMVDASSVNEYLPHDLDNE
IVPVRETFEEIGAEVSWVSATETVEINLEDRVVEELEEDVDEEVITEDEVLGIDHEVLEQIDVDHAMEHVEYLAQDIGTR
PAGTSDEHKAADYLVEYYQDLGYEVNKQEFPVGFAGPEMAVLANVEIEDGEQWYGEIDYDHETEYGDDYPWGTFEERHGT
EWEMWASPGGLITEGKQEVRAEVVNVGSGDIEDIDEKVEDKIVLVEGDFRQLDPEEFGQIVVEVEDEGGDGVIIYNSGGP
GGALGQAFPPYMSEQANIPVLGASYIHGIWLEEMVANSDDGVELTIDTVVKEDLTSYNVEATKSADDENAPIIAVTGHYD
SVVSAPGANDNASGTAATMEMARVFKEYDGDVELRFINFGAEEVGLVGSRYYVEQLSQDEQERFKGVYNPDMVATSDPYI
EHLFAQTVDGEPNLVTDSMKEADKALGYEEVAQGQFSASDHLPFHEAGIPAALFIHMSGEGTQEDFYTEPVYHTPLDTVE
DNICEDRYEKALEIIGTAVLDVIN
>Mature_584_residues
MFKGGKNLGITVLALFILLIGSQVGSQAAFGGVSHIQETSELSLEIDGQEIETDLQLEQGRTMVDASSVNEYLPHDLDNE
IVPVRETFEEIGAEVSWVSATETVEINLEDRVVEELEEDVDEEVITEDEVLGIDHEVLEQIDVDHAMEHVEYLAQDIGTR
PAGTSDEHKAADYLVEYYQDLGYEVNKQEFPVGFAGPEMAVLANVEIEDGEQWYGEIDYDHETEYGDDYPWGTFEERHGT
EWEMWASPGGLITEGKQEVRAEVVNVGSGDIEDIDEKVEDKIVLVEGDFRQLDPEEFGQIVVEVEDEGGDGVIIYNSGGP
GGALGQAFPPYMSEQANIPVLGASYIHGIWLEEMVANSDDGVELTIDTVVKEDLTSYNVEATKSADDENAPIIAVTGHYD
SVVSAPGANDNASGTAATMEMARVFKEYDGDVELRFINFGAEEVGLVGSRYYVEQLSQDEQERFKGVYNPDMVATSDPYI
EHLFAQTVDGEPNLVTDSMKEADKALGYEEVAQGQFSASDHLPFHEAGIPAALFIHMSGEGTQEDFYTEPVYHTPLDTVE
DNICEDRYEKALEIIGTAVLDVIN

Specific function: Catalyzes the hydrolysis of a range of N-terminal amino acids [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28B subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319763, Length=176, Percent_Identity=28.9772727272727, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484
- InterPro:   IPR003137 [H]

Pfam domain/function: PF02225 PA; PF04389 Peptidase_M28 [H]

EC number: =3.4.11.6; =3.4.11.10 [H]

Molecular weight: Translated: 64395; Mature: 64395

Theoretical pI: Translated: 3.67; Mature: 3.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKGGKNLGITVLALFILLIGSQVGSQAAFGGVSHIQETSELSLEIDGQEIETDLQLEQG
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHCCCEEEEECCCHHCCCHHHHCC
RTMVDASSVNEYLPHDLDNEIVPVRETFEEIGAEVSWVSATETVEINLEDRVVEELEEDV
CEEEEHHHHHHHCCCCCCCCEECHHHHHHHHCCCEEEEECCEEEEECCHHHHHHHHHHHH
DEEVITEDEVLGIDHEVLEQIDVDHAMEHVEYLAQDIGTRPAGTSDEHKAADYLVEYYQD
HHHHCCCCHHCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LGYEVNKQEFPVGFAGPEMAVLANVEIEDGEQWYGEIDYDHETEYGDDYPWGTFEERHGT
CCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCHHCCCC
EWEMWASPGGLITEGKQEVRAEVVNVGSGDIEDIDEKVEDKIVLVEGDFRQLDPEEFGQI
CEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHCEE
VVEVEDEGGDGVIIYNSGGPGGALGQAFPPYMSEQANIPVLGASYIHGIWLEEMVANSDD
EEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCC
GVELTIDTVVKEDLTSYNVEATKSADDENAPIIAVTGHYDSVVSAPGANDNASGTAATME
CEEEEHHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCHHHHHH
MARVFKEYDGDVELRFINFGAEEVGLVGSRYYVEQLSQDEQERFKGVYNPDMVATSDPYI
HHHHHHHCCCCEEEEEEECCCHHHCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCHHH
EHLFAQTVDGEPNLVTDSMKEADKALGYEEVAQGQFSASDHLPFHEAGIPAALFIHMSGE
HHHHHHCCCCCCCEEHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHCCCCEEEEEEECCC
GTQEDFYTEPVYHTPLDTVEDNICEDRYEKALEIIGTAVLDVIN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFKGGKNLGITVLALFILLIGSQVGSQAAFGGVSHIQETSELSLEIDGQEIETDLQLEQG
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHCCCEEEEECCCHHCCCHHHHCC
RTMVDASSVNEYLPHDLDNEIVPVRETFEEIGAEVSWVSATETVEINLEDRVVEELEEDV
CEEEEHHHHHHHCCCCCCCCEECHHHHHHHHCCCEEEEECCEEEEECCHHHHHHHHHHHH
DEEVITEDEVLGIDHEVLEQIDVDHAMEHVEYLAQDIGTRPAGTSDEHKAADYLVEYYQD
HHHHCCCCHHCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LGYEVNKQEFPVGFAGPEMAVLANVEIEDGEQWYGEIDYDHETEYGDDYPWGTFEERHGT
CCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCHHCCCC
EWEMWASPGGLITEGKQEVRAEVVNVGSGDIEDIDEKVEDKIVLVEGDFRQLDPEEFGQI
CEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHCEE
VVEVEDEGGDGVIIYNSGGPGGALGQAFPPYMSEQANIPVLGASYIHGIWLEEMVANSDD
EEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCC
GVELTIDTVVKEDLTSYNVEATKSADDENAPIIAVTGHYDSVVSAPGANDNASGTAATME
CEEEEHHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCHHHHHH
MARVFKEYDGDVELRFINFGAEEVGLVGSRYYVEQLSQDEQERFKGVYNPDMVATSDPYI
HHHHHHHCCCCEEEEEEECCCHHHCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCHHH
EHLFAQTVDGEPNLVTDSMKEADKALGYEEVAQGQFSASDHLPFHEAGIPAALFIHMSGE
HHHHHHCCCCCCCEEHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHCCCCEEEEEEECCC
GTQEDFYTEPVYHTPLDTVEDNICEDRYEKALEIIGTAVLDVIN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 1806041 [H]