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The map label for this gene is hbpA [H]

Identifier: 188587013

GI number: 188587013

Start: 2570043

End: 2571641

Strand: Reverse

Name: hbpA [H]

Synonym: Nther_2405

Alternate gene names: 188587013

Gene position: 2571641-2570043 (Counterclockwise)

Preceding gene: 188587014

Following gene: 188587012

Centisome position: 81.24

GC content: 41.4

Gene sequence:

>1599_bases
GTGAAAAAATTTAACAAAAAGCCATTTTGGCTAGCAATTGTGCTATCTGGTCTTTTGGTGTTCACCTTGACAGGCTGTGG
AGAGCCTGATGTTGAGGACGAAGCCGAAGCACCAGAAGGAGAAGAAGAGGAAGAAATGGAAGAACGACTTGAAGAAGATC
ACTTGGTAGTTGCCCAGGGGGCAGATGCACCAACACTAGATCCTATTGGTGAAAACGATCAACCTTCTGCAAGAATTACA
GAGCAAATTTTTGACACTCTTGTGGAGCAGGACGAGAATATGGAGGTTCAGCCAGGACTGGCTGAAGACTGGGAACAGAT
CGATGATACTACTTACGAATTCTATCTTCGCGAAGGCGTTAAATTTCACAATGGTGAAGAGCTAACAGCTGAAGATGTTA
AATATTCATATCAAAGATTGTTAGATGAAGACGAAGCTTCCCCGGGAGCTTTTATTTTAGAAATGGTTGATGTTGATAAT
ATTGAAATTGTAGATGATTATACCGTGCAAATTCCTCTAGAAGAACCTTTTGCACCAATTCTTTATCATCTTGGTCACTC
AGTAACTGCCATTGTCAATGAAGATGCAGTTGAAGAACATGGCGATGACTTTGGACAGAATCCTGTAGGAACTGGGCCAT
TTAAATTTGACGATTGGGATATTGGAAACAGAATTGACCTAGTTAGTTTTGATGACCACTGGAGAGGAGAAGCTGGTGTA
GAGCAGCTTTCTTTCAGAAACATTGAAGAGGACACAAACAGAACTATTGAATTAGAAACAGGTGGTGCTGATATTATTTA
CGATGTAGCACCAACAGATCTTGAAAGAGTAGAAGATCATGAAGAATTAACTCTTTTAAGAGAACCTAACTTGTCAACTG
AGTATATTGGCTTTAATATTGACAAAGAACCCTTTGATGATGAAAGGGTACGACAAGCAATTAACTATGCATTAGATATG
GAACCAATTGTCGAAGGAGTATATTATGGACTGGGAGAACCTGCTAGAAGTCCCCTTGCTCCAGCAGTAGTGCACAATAA
TCAAGATGTAAAATCTTATGAGCAGGATATGGAGAGAGCTGAAGAACTACTGGCTGAAGCTGGCTATGAAGACGGATTTG
AAGCAGAAATCTGGACTAATGACCAGCAGCAGCGTCAGGACATCGCTGAAATGGTACAAGGCCAGTTGTCTCAACTGGGT
ATTGACCTAAACATCAGCATTCGCGAGTGGGGAACTTATCTTGAAGAAACTGCCCAAGGAGAGCATGATATGTTCATACT
TGGCTGGGTTTCAGTAACCGGTGATGCCGATTACGGATTATACTCCCTATTCCATGGTGATGAGCATGGAGCAGCCGGAA
ACAGAACTTTCTATGATAATGACAGAGTAGACGAACTTCTAGACGAAGGTCGTAGAACTTTCGATGAAGATGAGCGTGCT
GAGATCTATGCGGAAATTCAAGAAATAGTTACTGAAGAAGCTCCTTGGATCTTTACTCAAGTGGGTGAAGAAGCAGTTGG
TACTAGAGATTTTGTAGAGAACTTTACTATTAATCCTGCAGGCCACCATGACCTGTTTGAGGTAACTATTGCAGATTAA

Upstream 100 bases:

>100_bases
AGAAAATTAGAAAGATTGAGGGGGTGAGAAGGCCGACTGCAGGATGTTTGGGCGCTTTAAATTACAAAAGCGTTAAAATC
GAAACAAGGAGGGGACAATA

Downstream 100 bases:

>100_bases
TCTGATTGCGTTCTTTTCTGACTAAGGAATTTGTAGGCCATGGATCGTCTCCATGGCCTATTTATAGAAAACATGAAGTA
TAACAGTTTAAAATAGCATA

Product: extracellular solute-binding protein family 5

Products: NA

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MKKFNKKPFWLAIVLSGLLVFTLTGCGEPDVEDEAEAPEGEEEEEMEERLEEDHLVVAQGADAPTLDPIGENDQPSARIT
EQIFDTLVEQDENMEVQPGLAEDWEQIDDTTYEFYLREGVKFHNGEELTAEDVKYSYQRLLDEDEASPGAFILEMVDVDN
IEIVDDYTVQIPLEEPFAPILYHLGHSVTAIVNEDAVEEHGDDFGQNPVGTGPFKFDDWDIGNRIDLVSFDDHWRGEAGV
EQLSFRNIEEDTNRTIELETGGADIIYDVAPTDLERVEDHEELTLLREPNLSTEYIGFNIDKEPFDDERVRQAINYALDM
EPIVEGVYYGLGEPARSPLAPAVVHNNQDVKSYEQDMERAEELLAEAGYEDGFEAEIWTNDQQQRQDIAEMVQGQLSQLG
IDLNISIREWGTYLEETAQGEHDMFILGWVSVTGDADYGLYSLFHGDEHGAAGNRTFYDNDRVDELLDEGRRTFDEDERA
EIYAEIQEIVTEEAPWIFTQVGEEAVGTRDFVENFTINPAGHHDLFEVTIAD

Sequences:

>Translated_532_residues
MKKFNKKPFWLAIVLSGLLVFTLTGCGEPDVEDEAEAPEGEEEEEMEERLEEDHLVVAQGADAPTLDPIGENDQPSARIT
EQIFDTLVEQDENMEVQPGLAEDWEQIDDTTYEFYLREGVKFHNGEELTAEDVKYSYQRLLDEDEASPGAFILEMVDVDN
IEIVDDYTVQIPLEEPFAPILYHLGHSVTAIVNEDAVEEHGDDFGQNPVGTGPFKFDDWDIGNRIDLVSFDDHWRGEAGV
EQLSFRNIEEDTNRTIELETGGADIIYDVAPTDLERVEDHEELTLLREPNLSTEYIGFNIDKEPFDDERVRQAINYALDM
EPIVEGVYYGLGEPARSPLAPAVVHNNQDVKSYEQDMERAEELLAEAGYEDGFEAEIWTNDQQQRQDIAEMVQGQLSQLG
IDLNISIREWGTYLEETAQGEHDMFILGWVSVTGDADYGLYSLFHGDEHGAAGNRTFYDNDRVDELLDEGRRTFDEDERA
EIYAEIQEIVTEEAPWIFTQVGEEAVGTRDFVENFTINPAGHHDLFEVTIAD
>Mature_532_residues
MKKFNKKPFWLAIVLSGLLVFTLTGCGEPDVEDEAEAPEGEEEEEMEERLEEDHLVVAQGADAPTLDPIGENDQPSARIT
EQIFDTLVEQDENMEVQPGLAEDWEQIDDTTYEFYLREGVKFHNGEELTAEDVKYSYQRLLDEDEASPGAFILEMVDVDN
IEIVDDYTVQIPLEEPFAPILYHLGHSVTAIVNEDAVEEHGDDFGQNPVGTGPFKFDDWDIGNRIDLVSFDDHWRGEAGV
EQLSFRNIEEDTNRTIELETGGADIIYDVAPTDLERVEDHEELTLLREPNLSTEYIGFNIDKEPFDDERVRQAINYALDM
EPIVEGVYYGLGEPARSPLAPAVVHNNQDVKSYEQDMERAEELLAEAGYEDGFEAEIWTNDQQQRQDIAEMVQGQLSQLG
IDLNISIREWGTYLEETAQGEHDMFILGWVSVTGDADYGLYSLFHGDEHGAAGNRTFYDNDRVDELLDEGRRTFDEDERA
EIYAEIQEIVTEEAPWIFTQVGEEAVGTRDFVENFTINPAGHHDLFEVTIAD

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787052, Length=455, Percent_Identity=30.989010989011, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI1789966, Length=477, Percent_Identity=30.398322851153, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1787762, Length=483, Percent_Identity=27.536231884058, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1787551, Length=472, Percent_Identity=25.4237288135593, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787495, Length=506, Percent_Identity=26.2845849802372, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1789397, Length=464, Percent_Identity=26.5086206896552, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI87081878, Length=514, Percent_Identity=24.7081712062257, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1789887, Length=472, Percent_Identity=23.9406779661017, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87082063, Length=277, Percent_Identity=24.9097472924188, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786256, Length=157, Percent_Identity=30.5732484076433, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60417; Mature: 60417

Theoretical pI: Translated: 3.71; Mature: 3.71

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFNKKPFWLAIVLSGLLVFTLTGCGEPDVEDEAEAPEGEEEEEMEERLEEDHLVVAQG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECC
ADAPTLDPIGENDQPSARITEQIFDTLVEQDENMEVQPGLAEDWEQIDDTTYEFYLREGV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHCCHHHHHHHHCCC
KFHNGEELTAEDVKYSYQRLLDEDEASPGAFILEMVDVDNIEIVDDYTVQIPLEEPFAPI
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEECEEEEEECCCCHHHH
LYHLGHSVTAIVNEDAVEEHGDDFGQNPVGTGPFKFDDWDIGNRIDLVSFDDHWRGEAGV
HHHHCCCEEEEECHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCH
EQLSFRNIEEDTNRTIELETGGADIIYDVAPTDLERVEDHEELTLLREPNLSTEYIGFNI
HHHHHCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHCCHHHEEEEECCCCCCEEEEECC
DKEPFDDERVRQAINYALDMEPIVEGVYYGLGEPARSPLAPAVVHNNQDVKSYEQDMERA
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHH
EELLAEAGYEDGFEAEIWTNDQQQRQDIAEMVQGQLSQLGIDLNISIREWGTYLEETAQG
HHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCC
EHDMFILGWVSVTGDADYGLYSLFHGDEHGAAGNRTFYDNDRVDELLDEGRRTFDEDERA
CCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
EIYAEIQEIVTEEAPWIFTQVGEEAVGTRDFVENFTINPAGHHDLFEVTIAD
HHHHHHHHHHHCCCCEEHHHHCHHHCCCHHHHHCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MKKFNKKPFWLAIVLSGLLVFTLTGCGEPDVEDEAEAPEGEEEEEMEERLEEDHLVVAQG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECC
ADAPTLDPIGENDQPSARITEQIFDTLVEQDENMEVQPGLAEDWEQIDDTTYEFYLREGV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHCCHHHHHHHHCCC
KFHNGEELTAEDVKYSYQRLLDEDEASPGAFILEMVDVDNIEIVDDYTVQIPLEEPFAPI
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEECEEEEEECCCCHHHH
LYHLGHSVTAIVNEDAVEEHGDDFGQNPVGTGPFKFDDWDIGNRIDLVSFDDHWRGEAGV
HHHHCCCEEEEECHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCH
EQLSFRNIEEDTNRTIELETGGADIIYDVAPTDLERVEDHEELTLLREPNLSTEYIGFNI
HHHHHCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHCCHHHEEEEECCCCCCEEEEECC
DKEPFDDERVRQAINYALDMEPIVEGVYYGLGEPARSPLAPAVVHNNQDVKSYEQDMERA
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHH
EELLAEAGYEDGFEAEIWTNDQQQRQDIAEMVQGQLSQLGIDLNISIREWGTYLEETAQG
HHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCC
EHDMFILGWVSVTGDADYGLYSLFHGDEHGAAGNRTFYDNDRVDELLDEGRRTFDEDERA
CCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
EIYAEIQEIVTEEAPWIFTQVGEEAVGTRDFVENFTINPAGHHDLFEVTIAD
HHHHHHHHHHHCCCCEEHHHHCHHHCCCHHHHHCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]