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The map label for this gene is gsiC [H]

Identifier: 188587012

GI number: 188587012

Start: 2568930

End: 2569856

Strand: Reverse

Name: gsiC [H]

Synonym: Nther_2404

Alternate gene names: 188587012

Gene position: 2569856-2568930 (Counterclockwise)

Preceding gene: 188587013

Following gene: 188587011

Centisome position: 81.18

GC content: 42.93

Gene sequence:

>927_bases
ATGCATAAGTATATATTTAATCGACTCCTCCAGTTAATCCCTGTCCTTCTAGGAGTAGTTTTCATAGTTTTCACGATTAT
GTATATAACTCCTGGAGACCCGGCACTGATTTTGCTGGGTGAACAAGCTCCAGAACATCAGGTAAAACAACTGCGACGGG
AAATGGGTCTACATTTACCATTCTTTCAACAGTTTTTGAATTACTTGACGGATGTTATACAGGGAGATTTTGGCTACTCC
TTGACAACTGGTAGACCGGTATTGGTTGAGATTATGGCACGGTTTCCAAACACATTAGTTTTATCAACTGGTGCTATCTT
TTTGGCAGTAATAATTGGCATCCCTGCAGGGATAATTTCTGCAGTGCGCCAGAACTCTGCTATTGATAACGTGACTATGG
TGGGAGCCCTCTTAGGTGTGTCACTTCCTAACTTTTGGCAGGGTATGATGGCAATTCTATTATTTTCAGTGTTGTTTCCC
ATATTTCCGTCATCAGGATTTGATACCTGGCAGCATGCCGTGCTTCCAATAGTCACTCTTGGGACGAGCAGTGCTGGTCT
TATTACTCGTATGACCCGTTCATCCATGCTGGAAGTACTGCGTCAGGATTATATCCGTACTGCCAAGGCTAAGGGGCTAA
ATGAGCGTACAGTAATTGTAAAGCACGCTCTAAAAAATGCCTTAATACCGGTAGTAACTGTCATTGGACTTCAGTTCGGG
TTCCTACTGGGAGGAGCAGTATTGACGGAAACTATTTTCTCTATTCCCGGTTTGGGAAGGCTGATAGTGGACAGTATTCG
CGAACAGAACTTTACAGTAGTACAGGGTGGAGTACTGTTCATCGCTATTGTGTTTTCACTAGTCAATTTGTTGGTAGACA
TTTTCTATGCTTTCTTAGACCCACGTATCAAGGCCCAGTATCAGTAA

Upstream 100 bases:

>100_bases
TTTAAAATAGCATAAAAGCAAAAGCATTACAAAGCTTTAAAATAGTATGTAGTTTTATTTATTTGTTCTATAGGTCTTAT
TAAAGGGAGGGAAAACTTGT

Downstream 100 bases:

>100_bases
GAGAAGCAGTTTGACAAGGTCTCTTAACTTTTGTTTTTAAGGAGGTAGATGAGGCATGGCAGAATCAGAAACCCAAAAAA
ATACCTCTGTCACGGAAAGT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MHKYIFNRLLQLIPVLLGVVFIVFTIMYITPGDPALILLGEQAPEHQVKQLRREMGLHLPFFQQFLNYLTDVIQGDFGYS
LTTGRPVLVEIMARFPNTLVLSTGAIFLAVIIGIPAGIISAVRQNSAIDNVTMVGALLGVSLPNFWQGMMAILLFSVLFP
IFPSSGFDTWQHAVLPIVTLGTSSAGLITRMTRSSMLEVLRQDYIRTAKAKGLNERTVIVKHALKNALIPVVTVIGLQFG
FLLGGAVLTETIFSIPGLGRLIVDSIREQNFTVVQGGVLFIAIVFSLVNLLVDIFYAFLDPRIKAQYQ

Sequences:

>Translated_308_residues
MHKYIFNRLLQLIPVLLGVVFIVFTIMYITPGDPALILLGEQAPEHQVKQLRREMGLHLPFFQQFLNYLTDVIQGDFGYS
LTTGRPVLVEIMARFPNTLVLSTGAIFLAVIIGIPAGIISAVRQNSAIDNVTMVGALLGVSLPNFWQGMMAILLFSVLFP
IFPSSGFDTWQHAVLPIVTLGTSSAGLITRMTRSSMLEVLRQDYIRTAKAKGLNERTVIVKHALKNALIPVVTVIGLQFG
FLLGGAVLTETIFSIPGLGRLIVDSIREQNFTVVQGGVLFIAIVFSLVNLLVDIFYAFLDPRIKAQYQ
>Mature_308_residues
MHKYIFNRLLQLIPVLLGVVFIVFTIMYITPGDPALILLGEQAPEHQVKQLRREMGLHLPFFQQFLNYLTDVIQGDFGYS
LTTGRPVLVEIMARFPNTLVLSTGAIFLAVIIGIPAGIISAVRQNSAIDNVTMVGALLGVSLPNFWQGMMAILLFSVLFP
IFPSSGFDTWQHAVLPIVTLGTSSAGLITRMTRSSMLEVLRQDYIRTAKAKGLNERTVIVKHALKNALIPVVTVIGLQFG
FLLGGAVLTETIFSIPGLGRLIVDSIREQNFTVVQGGVLFIAIVFSLVNLLVDIFYAFLDPRIKAQYQ

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=45.0980392156863, Blast_Score=287, Evalue=5e-79,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=43.952802359882, Blast_Score=274, Evalue=5e-75,
Organism=Escherichia coli, GI1787761, Length=326, Percent_Identity=41.7177914110429, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI1789888, Length=309, Percent_Identity=35.5987055016181, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1787497, Length=308, Percent_Identity=34.4155844155844, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=31.0469314079422, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788504, Length=362, Percent_Identity=26.5193370165746, Blast_Score=121, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33960; Mature: 33960

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKYIFNRLLQLIPVLLGVVFIVFTIMYITPGDPALILLGEQAPEHQVKQLRREMGLHLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCH
FFQQFLNYLTDVIQGDFGYSLTTGRPVLVEIMARFPNTLVLSTGAIFLAVIIGIPAGIIS
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCHHHHH
AVRQNSAIDNVTMVGALLGVSLPNFWQGMMAILLFSVLFPIFPSSGFDTWQHAVLPIVTL
HHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEE
GTSSAGLITRMTRSSMLEVLRQDYIRTAKAKGLNERTVIVKHALKNALIPVVTVIGLQFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGAVLTETIFSIPGLGRLIVDSIREQNFTVVQGGVLFIAIVFSLVNLLVDIFYAFLD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHC
PRIKAQYQ
CCHHCCCC
>Mature Secondary Structure
MHKYIFNRLLQLIPVLLGVVFIVFTIMYITPGDPALILLGEQAPEHQVKQLRREMGLHLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCH
FFQQFLNYLTDVIQGDFGYSLTTGRPVLVEIMARFPNTLVLSTGAIFLAVIIGIPAGIIS
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCHHHHH
AVRQNSAIDNVTMVGALLGVSLPNFWQGMMAILLFSVLFPIFPSSGFDTWQHAVLPIVTL
HHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEE
GTSSAGLITRMTRSSMLEVLRQDYIRTAKAKGLNERTVIVKHALKNALIPVVTVIGLQFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGAVLTETIFSIPGLGRLIVDSIREQNFTVVQGGVLFIAIVFSLVNLLVDIFYAFLD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHC
PRIKAQYQ
CCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]